The invention relates to a medicament formula and a preparation thereof for preventing and curing an altitude reaction and a
coronary heart disease. The medicament formula comprises 10 to 40g of
rhodiola rosea, 60 to 150g of
salvia miltiorrhiza, 1 to 5g of
ginkgo biloba extract and 0.3 to 1.5g of artificial musk or
borneol. The preparation comprises oral
solid preparations of dripping pills, troches, capsulas, granules, pills,
powder, and the like. The preparation method of dripping pills is characterized by extracting
salvianolic acid B of
salvia miltiorrhiza extract by adopting a method combining
alcohol extraction and
ethyl acetate extraction, the purifying method adopts macroporous adsorbent resins, and an eluent is 20% to 60%
ethanol. The extraction of
salidroside of
rhodiola rosea extract adopts 30 to 90%
ethanol for heating and
backflow, the purifying method adopts the macroporous adsorbent resins, and the eluent is 10 to 50%
ethanol. A
salvia miltiorrhiza purified matter (
salvianolic acid B), a
rhodiola rosea purified matter (high-purity
salidroside), the
ginkgo biloba extract and the artificial musk or
borneol are mixed with PEG (polyethyleneglycol) 4000 and PEG 6000 which are 0.5-3 times the amount of the
salvia miltiorrhiza purified matter (
salvianolic acid B), the
rhodiola rosea purified matter (high-purity
salidroside), the
ginkgo biloba extract and the artificial musk or
borneol, the , the mixture is heated for fusion and kept at 60 to 80 DEG C, and the mixture is dropped to a
coolant, condensated, screened and dried to obtain the preparation.