The invention relates to a medicament formula and a preparation thereof for preventing and curing an altitude reaction and a 
coronary heart disease. The medicament formula comprises 10 to 40g of 
rhodiola rosea, 60 to 150g of 
salvia miltiorrhiza, 1 to 5g of 
ginkgo biloba extract and 0.3 to 1.5g of artificial musk or 
borneol. The preparation comprises oral 
solid preparations of dripping pills, troches, capsulas, granules, pills, 
powder, and the like. The preparation method of dripping pills is characterized by extracting 
salvianolic acid B of 
salvia miltiorrhiza extract by adopting a method combining 
alcohol extraction and 
ethyl acetate extraction, the purifying method adopts macroporous adsorbent resins, and an eluent is 20% to 60% 
ethanol. The extraction of 
salidroside of 
rhodiola rosea extract adopts 30 to 90% 
ethanol for heating and 
backflow, the purifying method adopts the macroporous adsorbent resins, and the eluent is 10 to 50% 
ethanol. A 
salvia miltiorrhiza purified matter (
salvianolic acid B), a 
rhodiola rosea purified matter (high-purity 
salidroside), the 
ginkgo biloba extract and the artificial musk or 
borneol are mixed with PEG (polyethyleneglycol) 4000 and PEG 6000 which are 0.5-3 times the amount of the 
salvia miltiorrhiza purified matter (
salvianolic acid B), the 
rhodiola rosea purified matter (high-purity 
salidroside), the 
ginkgo biloba extract and the artificial musk or 
borneol, the , the mixture is heated for fusion and kept at 60 to 80 DEG C, and the mixture is dropped to a 
coolant, condensated, screened and dried to obtain the preparation.