23 results about "Implantable Neurostimulators" patented technology

The invention relates to an in-vitro program controller and a control method thereof. The in-vitro program controller comprises a sensor and a processor, and the processor sets the working power of the implantable nerve stimulator, a temperature early warning value and a temperature upper limit value greater than the temperature early warning value according to the stimulation parameters; when the movement of the in-vitro program control instrument is determined at every reference time interval or according to the posture change detected by the sensor, a data reading instruction is sent to the implantable nerve stimulator so as to read the working power and temperature of the implantable nerve stimulator; increasing, decreasing or maintaining the transmitting power according to the comparison between the read working power and the set working power; according to the fact that the read temperature is larger than or equal to the set temperature early warning value and smaller than the set temperature upper limit value, the transmitting power is reduced; and sending a stimulation stop instruction when the read temperature is greater than or equal to a set temperature upper limit value. According to the invention, the working power, temperature and the like of the implantable nerve stimulator can be monitored and adjusted, so that safe treatment of a patient is ensured.

The utility model discloses a nerve stimulator assembly implanted into a skull, and belongs to the technical field of medical instruments. The nerve stimulator assembly implanted into the skull comprises a stimulator with a through hole, a fixing base and a fixing piece, the fixing base comprises a base plate and a limiting table arranged on the base plate, and the stimulator is detachably connected with the fixing base; the fixing column penetrates through the through hole to be fixedly held with the limiting table. According to the nerve stimulator assembly implanted into the skull, the stimulator and the fixed base can be fixedly connected, and the stimulator and the fixed base are prevented from being disengaged and losing efficacy.

The application provides an implantable nerve stimulator suitable for human limbs, and belongs to the technical field of medical devices, and comprises: sequentially connected cylindrical end part, shell part and tail part; the shell part is internally provided with a circuit board; the end part is internally provided with a wireless charging coil, and the central axis of the wireless charging coil is parallel to the length direction of the shell part; the tail part is internally provided with an electrode connector for inserting an electrode, and the electrode connector connection channel is arranged in parallel to the length direction of the shell part; the implantable nerve stimulator of the application optimizes the layout of internal components, thereby reducing the overall width and thickness of the nerve stimulation electrode, so as to facilitate implantation in the human limb part.

A system is provided for driving an implantable neurostimulator lead, the lead having an associated plurality of electrodes disposed in at least one array on the lead. The system comprises an implantable pulse generator (IPG), the IPG including an electrode driver, a load system for determining load requirements, an IPG power coupler, and an IPG communication system. The system also includes an external unit, which includes an external variable power generator, an external power coupler, an external communication system, and a controller for varying the power level of the variable power generator.

The present invention relates to a stimulation generator suitable for use in an implantable neurostimulator, including an injectable neurostimulator. The stimulation generator is adapted to provide a configurable stimulation signal comprising a component, such as a pulse. The stimulation generator comprises circuitry to receive and combine an amplitude control signal and a duty cycle signal to produce a preliminary output voltage signal which includes the component of the stimulation signal. It further comprises a voltage-controlled current source adapted to be driven by the preliminary output voltage signal; and a mode selector controlled by a stimulation mode signal to output the component from the preliminary output voltage signal as a current-controlled component of the stimulation signal via the voltage-controlled current source or as a voltage-controlled component of the stimulation signal.

The present disclosure provides a potential signal acquisition method and an implantable nerve stimulator, wherein the method comprises: outputting a pulse stimulation signal to a stimulation target; performing passive charge balance on the stimulation target after the end of the stimulation pulse of the pulse stimulation signal; and acquiring a potential signal of the target stimulation target after the end of the passive charge balance and before the start of the next stimulation pulse.

A method of treatment with an implantable neurostimulator device in which a low frequency waveform is applied by a pulse generator configured therein through a plurality of electrodes to a network of target interactive brain regions subject to an abnormal communication connection, in particular a central execution network, a default mode network and / or a highlight network, in some embodiments, the network may be configured to restore normal correlation or anti-correlation communication connections within and between networks to deal with brain-related dysfunctions.

The invention relates to an RFID protocol based communication method for an implantable nerve stimulator system. The implantable nerve stimulator system comprises an in-vitro program control instrument and an implantable nerve stimulator, and the in-vitro program control instrument and the implantable nerve stimulator are in wireless communication by adopting a predetermined RFID protocol. The in-vitro program controller is configured to send a signal containing energy and control information to the implantable nerve stimulator. The implantable nerve stimulator is configured to: generate a sequence of stimulation pulses for application to the electrodes using the received stimulation parameters; self-state self-checking is executed according to a preset self-checking period; and when a query instruction from the in-vitro program controller is received, a state self-checking result is fed back to the in-vitro program controller. The frame structure of the predetermined RFID protocol comprises a seeker and a command field, and the seeker adopts a configuration mode of forbidding a lead code extension control bit; the command field includes a 4-bit command code, 8-bit or more valid data bits, and 5-bit CRC check bits.

The present disclosure provides a potential signal acquisition method and an implantable nerve stimulator, wherein the method comprises: outputting a pulse stimulation signal to a stimulation target; actively balancing charges of the stimulation target after the stimulation pulse of the pulse stimulation signal ends; and acquiring a potential signal of the target after the active charge balancing ends and before the next stimulation pulse starts.

The invention relates to a wireless directional energy transfer system of a medical in-vitro program controller. The wireless directional energy transfer system comprises: a control device configured to generate a control signal for stimulation parameters of an in-vivo implantable nerve stimulator; a transceiver configured to convert the received control signal into an initial radio frequency signal; the transmitting link is used for transmitting the received initial radio-frequency signal to each of the plurality of transmitting branches, and each of the plurality of transmitting branches is used for processing the initial radio-frequency signal into a transmitting radio-frequency signal; the in-vitro antenna is used for transmitting a transmitted radio-frequency signal to the in-vivo antenna or receiving a radio-frequency signal from the in-vivo antenna; and the receiving link sends the received radio frequency signal to one of the plurality of receiving branches, and each of the plurality of receiving branches processes the received radio frequency signal into a received radio frequency signal and sends the received radio frequency signal to the transceiver, so that the transceiver converts the received radio frequency signal into a control signal and sends the control signal to the control device.

Systems and methods for customizable titration of an implantable neurostimulator are provided. A method of titrating a neurostimulation signal delivered to a patient from an implantable pulse generator includes delivering a first neurostimulation signal with a first set of parameters, increasing a first value of the first neurostimulation signal at a first rate for a first period of time while delivering the first neurostimulation signal, ceasing delivery of the first neurostimulation signal when the first value reaches a first target value, delivering a second neurostimulation signal with a second set of parameters, and increasing the second neurostimulation signal at a second rate for a second period of time while delivering the second neurostimulation signal.

Devices and systems for providing neurostimulation to a target location, may include an implantable neurostimulator device including a first transducer device that includes a gas matrix piezoelectric (GMP) array or a piezoelectric micromachined ultra-sound transducer (pMUT) array; the implantable neurostimulator device has a length of 5 mm to 20 mm and a diameter of 1 mm to 5 mm and an energy delivery device including a second transducer device; the second transducer device includes a gas matrix piezoelectric (GMP) array, a polymer matrix piezocomposite array, a capacitive micro-machined acoustic transducer (cMUT) array, or a pMUT ar-2024 / 097917 ray; and a beam-forming processor to cause the second transducer device to produce an acoustic wave, the implantable neurostimulator device is to receive the acoustic wave from the energy delivery device, convert the acoustic wave to an electrical energy signal, and apply the electrical energy signal.

An implant system is provided, which includes an implant, including an implant body and an electrode disposed on the implant body; and a hollow needle, which is configured to be percutaneously advanceable into tissue of a subject. The hollow needle is shaped so as to define a lumen dimensioned to house the implant; at a distal end of the hollow needle, a distal end opening configured to facilitate passage of the implant therethrough from the lumen; and a lateral wall shaped so as to define a window therethrough to the lumen. Other embodiments are also described.

The application discloses a closed-loop synergistic electrical stimulation system for diuresis and defecation dysfunction. The closed-loop synergistic electrical stimulation system comprises an implantable nerve stimulator, a bladder puncture probe electrode, a pressure sensor integrated with a tip for real-time acquisition of intravesical pressure signals, a sacral nerve stimulation electrode for implantation of sacral foramen to regulate micturition reflex and defecation reflex, the implantable nerve stimulator adjusts the pulse electrical stimulation output to the sacral nerve stimulation electrode to assist the user in urination according to the intravesical pressure signals collected by the pressure sensor, and the implantable nerve stimulator outputs pulse electrical stimulation to the sacral nerve stimulation electrode to assist the user in defecation in response to a manual trigger instruction issued by the user through an external program control instrument. The application realizes the integration and synergy of automatic regulation of micturition and manual assistance of defecation, adopts a single nerve stimulator two-drag-two design which can be implanted for a long time, and provides a safe and effective solution for diuresis and defecation dysfunction.

The present application relates to an implantable nerve stimulator, an external programmer and an implantable nerve stimulator system. The implantable nerve stimulator comprises an antenna, a stimulation parameter register, a CRC register and a processor. The processor generates a stimulation voltage by using received energy, and generates a stimulation pulse sequence by using stimulation parameters stored in the stimulation parameter register; when antenna position offset is determined according to the stimulation voltage during stimulation, the stimulation is paused, and a state of the stimulation pause is sent to the external programmer; when it is determined that the external programmer reads the CRC code stored in the CRC register, the CRC code of the stimulation parameters stored in the stimulation parameter register is calculated by using the CRC register, and the calculated CRC code is sent to the external programmer to determine whether the antenna position offset causes the stimulation parameters stored in the stimulation parameter register to change. The present application can cope with the decrease of the stimulation voltage and the mutation of the stimulation parameters caused by the antenna offset.

The application discloses a biodegradable vagus nerve stimulation system and a preparation method and application thereof, and belongs to the field of medical devices. The biodegradable vagus nerve stimulation system comprises an implantable vagus nerve stimulator and an external focused ultrasound emission device used in cooperation with the implantable vagus nerve stimulator. The implantable vagus nerve stimulator comprises an ultrasound-driven degradable friction nanogenerator and a vagus nerve interface lead. The biodegradable vagus nerve stimulation system provided by the application realizes wireless energy supply for the implantable device and vagus nerve stimulation by constructing an ultrasound-driven frictional electric energy conversion mechanism, and fundamentally solves the dependence of traditional implantable devices on built-in batteries.

According to another disclosed embodiment, an energy efficient implantable neurostimulator for delivering one or more electrical pulses to a target region within a patient's body is provided. The neurostimulator includes a converter for generating the stimulation current, wherein the converter includes a voltage increasing circuit and a voltage reducing circuit. The stimulator may also include a current source that includes a pair of cascode arranged transistors that are controlled to maintain an amplitude of the stimulation current substantially constant. The neurostimulator may also include a bias voltage power supply that powers a selecting circuit for selecting one of the voltage increasing or voltage decreasing circuits.

A method of providing a sleep apnea nerve stimulation therapy to a subject may include detecting a respiratory waveform of the subject with a sensor. The sensor may be configured for coupling to the subject. The respiratory waveform may include a plurality of respiratory cycles each corresponding to at least one of a breath and an attempted breath of the subject. The method may also include identifying a breathing pattern within the respiratory waveform over a period of time. The breathing pattern may include a repeating pattern of a plurality of respiratory cycles followed by at least one respiratory cycle corresponding to a disordered breathing event. The method may also include generating a series of stimulation pulses with an implantable nerve stimulator configured for coupling to a hypoglossal nerve of the subject. The series of stimulation pulses may be coordinated with the breathing pattern.

The invention discloses a wireless charging positioning instrument based on an implantable nerve stimulator. The wireless charging locator comprises a shell, the shell comprises an upper cover plate and a lower cover plate, and the two ends of the upper cover plate are provided with connecting structures used for being connected with a fixing waistband. The mainboard is arranged in the shell; the wireless charging transmitting coil is used for wirelessly charging the implantable nerve stimulator through electromagnetic induction; the wireless communication coil is in information communication with the implantable nerve stimulator; the external cable interface is arranged on the side face of the shell, the mainboard is electrically connected with the external cable interface, and the wireless charging locator is electrically connected with the in-vitro program control charger through the external cable interface so that the wireless charging locator can wirelessly charge the implantable nerve stimulator. The wireless charging positioning instrument has the advantages of being accurate in positioning, reliable in communication, efficient in charging, electromagnetic compatible, safe in protection, comfortable to wear, high in impact resistance, convenient and fast to assemble and the like.

The invention provides a flexible electrode implantation assembly, a temporary nerve stimulator system and an implantable nerve stimulator system. The flexible electrode implantation assembly comprises a flexible paddle electrode, a flexible traction tube and a first guide wire. The flexible paddle electrode comprises a far-end contact part, and the far-end contact part is provided with an auxiliary fixing part. The flexible traction tube is provided with a far-end outlet and a far-end inlet. The first guide wire is movably arranged in the flexible traction tube in a penetrating mode, the far end of the first guide wire penetrates out of the far-end outlet, then is connected with the auxiliary fixing part and penetrates back into the tube cavity through the far-end inlet, and therefore a detachable traction ring part is formed outside the flexible traction tube, and the auxiliary fixing part is restrained on the outer wall of the flexible traction tube. According to the structure, when the flexible paddle-shaped electrode is conveyed, reliable conveying can be achieved through the flexible traction tube and the first guide wire, the far end of the flexible paddle-shaped electrode is attached to the outer wall of the flexible traction tube, and the problem that the flexible paddle-shaped electrode cannot be implanted to a target position in a minimally invasive and accurate mode due to the size of the flexible paddle-shaped electrode can be effectively solved.

The application provides a flexible electrode implanting assembly, a temporary nerve stimulator system and an implantable nerve stimulator system. The flexible electrode implanting assembly comprises a flexible paddle electrode, a flexible traction tube and a first guide wire. The flexible paddle electrode comprises a distal contact portion, and the distal contact portion is provided with an auxiliary fixing portion. The flexible traction tube is provided with a distal outlet and a distal inlet. The first guide wire is movably arranged in the flexible traction tube, the distal end of the first guide wire is connected with the auxiliary fixing portion after being led out of the distal outlet, and the first guide wire is led back into the lumen through the distal inlet, so that a detachable traction ring portion is formed outside the flexible traction tube to constrain the auxiliary fixing portion to the outer wall of the flexible traction tube. The above structure can realize reliable delivery through the flexible traction tube and the first guide wire when the flexible paddle electrode is delivered, and the distal end of the flexible paddle electrode is attached to the outer wall of the flexible traction tube, which can effectively solve the problem that the flexible paddle electrode cannot be minimally invasively and accurately implanted into the target position due to its own size.

The application relates to the technical field of medical products, and discloses a channel module and an implantable nerve stimulator. The channel module comprises a substrate, elastic conductive pieces and a module upper cover. The substrate is provided with a plurality of through holes for penetrating conductors. The elastic conductive pieces are installed on the substrate at intervals, and the elastic conductive pieces can be electrically connected to the conductors. The module upper cover is installed on the substrate and covers the elastic conductive pieces from above, and a channel for penetrating a wire is formed between the module upper cover and the elastic conductive pieces. The elastic conductive pieces replace the whole connector assembly in the prior art, the overall size of the channel module can be reduced, and the implantable nerve stimulator can be designed to be small.

The invention relates to a stimulation current error measurement device for an implantable nerve stimulator. The stimulation current error measurement apparatus may include: an actual stimulation voltage generation module configured to generate a sampling value of an actual stimulation voltage of a stimulation electrode; the stimulation error voltage generation module is configured to generate a plurality of preset stimulation error voltage thresholds; the stimulation voltage error comparison module is electrically connected with the stimulation voltage error generation module and the actual stimulation voltage generation module, and the stimulation voltage error comparison module is configured to receive a sampling value of the actual stimulation voltage and a plurality of preset stimulation error voltage thresholds; comparing the sampling value of the actual stimulation voltage with one or more of a plurality of preset stimulation error voltage thresholds, and generating a comparison result; and the control module is electrically connected with the stimulation voltage error comparison module, and the control module is configured to judge the relative error of the actual stimulation current based on the comparison result.