82results about "Ureters" patented technology

Set forth are vascular valves and servovalves and methods of using the same that may be positioned in the circulatory system without interrupting blood flow to facilitate solid organ transplantation so as to reduce graft organ anoxia and degradation before and after harvesting and storage, thereby minimizing late-term cardiac allograft vasculopathy as a major cause of graft failure. Along the urinary tract, bypassing bladder-generated urge sensation by diverting urine directly from the ureters to a neobladder or collection bag alleviates intractable incontinence, nocturia, urethral syndrome, overactive bladder, dysuria, or frequency. Where the lower tract is missing, a prosthesis can thwart disease and preclude the degenerative metaplastic transition to carcinoma risked when gut is used to construct a conduit for urine, a neobladder, and / or high-maintenance stoma. Druglines to valves and servovalves can directly pipeline-target medication to nidi, anastomoses, or any other trouble spots.

A stent comprising a tubular member, a lumen extending through the tubular member, a first retention structure and a second retention structure at opposite ends of the tubular member. The first retention structure comprises multiple coils and a removable anti-coiling material over the multiple coils of the first retention structure to present the multiple coils as an elongated extension of the tubular member, whereupon removal of the removable anti-coiling material at least one of the multiple coils of the first retention structure is presented and any excess coils can be trimmed.

The invention relates to a ureteral access sheath (10) for insertion in the ureter (56) of a human or animal patient, wherein the access sheath (10) has, at a proximal end, an introduction portion (16) for a medical instrument and has an elongate portion (18) which extends from the proximal introduction portion (16) to a distal end (12) of the access sheath (10), wherein the elongate portion (18) comprises, over at least substantially the length of the elongate portion (18), at least one lumen (20) for guiding through the medical instrument. According to the invention, at least in some regions along the elongate portion (18), an elastically deformable cover element (22) is arranged on an outer wall of the lumen (20), wherein the cover element (22) can be deformed between a basic position, in which the cover element (22) rests against the outer wall of the lumen (20), and a guide-wire position, in which the cover element (22) is moved away from the outer wall of the lumen (20) by a guide wire (24) and forms a guide channel (26) for the guide wire (24).

A stent is disclosed that is configured to maintain patency of the prostatic urethra despite an enlarged prostate. The stent can include a handle that, in an undeflected position, is disposed outside of the flow path of the stent. When the handle is pulled, the handle can deflect to generally aligned with a central axis of the stent. A capture device is disclosed that includes a tapered tip to navigate a working channel of a delivery device and a hook that can capture the stent handle and be moved into a tube to retain the stent handle to facilitate maneuvering of the stent in and out of the working channel of the delivery device. A loading adapter with a tapered port is disclosed that can be disposed on the delivery device to distribute compressive forces applied by the port on the stent during loading into the working channel.

Apparatus and methods are described for dilating a portion of a urethra surrounded by an enlarged prostate. The apparatus includes dilation device, and a delivery device including a balloon. The delivery device is configured to deliver the dilation device and the balloon to the portion of the urethra, while the dilation device is disposed in a helical configuration on the delivery device. Upon the balloon and the dilation device being disposed at the portion of the urethra, the delivery device is configured to expand the balloon, thereby expanding the portion of the urethra, and to cause the dilation device to radially expand from the helical configuration to an arc configuration. Subsequently, the delivery device is configured to implant the dilation device, from outside the balloon, into tissue of the prostate surrounding the portion of the urethra, while the portion of the urethra is expanded by the balloon.

A stent is disclosed that has an elongated body composed of a bioabsorbable polymer having a proximal end, a distal end, two open spiral channels formed on the exterior surface of the body to provide fluid communication between the proximal end and the distal end. The stent also has a central lumen open at the proximal and distal ends of the stent for the passage of a guide wire. A method for using the stent and a kit containing the stent are also disclosed.

A method for expanding a constricted location of a urethra of a subject, the method including inserting a urethral implant, and an implant sheath that covers the urethral implant, through the urethra for implanting the urethral implant in the constricted location, the urethral implant being in a compressed configuration within the implant sheath, releasing the urethral implant from the implant sheath until the urethral implant exits from the implant sheath, thereby expanding the urethral implant from the compressed configuration to an expanded configuration, applying, by the urethral implant, continuous pressure on tissues of the urethra at the constricted location, and retracting the implant sheath from the urethra.

Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.

A method for expanding a constricted location of a urethra of a subject, the method including inserting a urethral implant, and an implant sheath that covers the urethral implant, through the urethra for implanting the urethral implant in the constricted location, the urethral implant being in a compressed configuration within the implant sheath, releasing the urethral implant from the implant sheath until the urethral implant exits from the implant sheath, thereby expanding the urethral implant from the compressed configuration to an expanded configuration, applying, by the urethral implant, continuous pressure on tissues of the urethra at the constricted location, and retracting the implant sheath from the urethra.

The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.

A packaging system (10b) is provided that includes a packaging body defining a cavity (14b) and a seal (18b) configured to be joined to the packaging body to fluidly seal the cavity. The packaging system may also include at least one tissue cradle (16b) configured to be disposed within the cavity. A cavity having a single size may be configured to accommodate differently sized tissue cradles. In addition to the cavity the packaging system may include one or more additional reservoirs configured for holding a volume of liquid. Such packaging systems may be used in the storage of wet-preserved or dry-preserved human or animal tissue. Also provided are a packaged tissue specimen and a method for packaging tissue.

The invention relates to a device (1000) for extracting a stent, in particular a ureteral stent, comprising: a casing portion (199) which is tubular and is connected, at a first end, to a handle portion (300) and has an opening (110) at the second end opposite the handle portion (300); and a catching element (200) which can be moved at least translationally in the casing portion (100) in the longitudinal direction of the casing portion (100) and has a catching portion (210) at the end thereof facing the opening (110) of the casing portion (100), the catching portion being designed to be brought into engagement with the stent. The catching portion (210) is designed in such a way that, after the catching portion (210) has been pushed out of the casing portion (100), the catching portion (210) can be folded down with respect to the rest of the catching element (200).

Medical implants that include a containment layer surrounding, or surrounded by, a biodegradable medical device provide the benefit that pieces formed during degradation of the medical device are held within a constrained place and thus do not causes injury to a hosts.

Provided in the present invention are a biodegradable ureteral stent and a preparation method therefor. The biodegradable ureteral stent is of a hollow circular tubular structure (1), a fixing structure (2) for preventing sliding is disposed at two ends or one end, a tube wall is also provided with a plurality of penetrating drainage side holes (3), and a material used is a composite material formed by at least a glycolide-ε-caprolactone copolymer, an ethylene oxide polymer, and a medical developer. In the glycolide-ε-caprolactone copolymer, a weight percentage content of glycolide is 51-58%, such that the copolymer has appropriate mechanical strength and softness and hardness and gradually becomes soft with prolonging of the degradation time. Meanwhile, a certain proportion of the ethylene oxide polymer is added, such that the polymer has a lower constant stretch modulus after degradation and is softer and smoother. Thus, degraded fragments are not prone to getting stuck and are easier to excrete from the body. The composite material of present invention is more suitable for preparing a biodegradable ureter stent.

The present disclosure relates to a gastrointestinal delivery device of a chitosan dressing, where the delivery device is capable of stop bleeding, in particular in connection with TURP procedures. The delivery device may be used in all gastrointestinal bleeding applications and can be used with a biocompatible, foldable, thin profile, chitosan dressing. Various aspects of the device and its uses are provided herein.

A urinary drainage prosthesis for patients following radical cystectomy, characterized in that it comprises a tube which is made of a hydrophilic matrix made of polypropylene or polyester mesh in the shape of a tube, ended with a collar on one side made of micro and / or nanofiber nonwoven fabric prepared from a synthetic fiber-forming polymer or copolymers, natural polymers such as esters and ethers of cellulose, collagen, gelatin, fibrinogen, natural silk, coated on the internal surface with a layer of cross-linked sodium hyaluronate of the average molecular weight from 2000 kD to 2 500 kD in the form of a film with an addition of the plasticizer - a polyol and on the external surface with a layer of type I collagen of the animal origin of the average molecular weight from 250 kD to 350 kD in the form of a nanofiber layer, whereby the sodium hyaluronate layer amounts from 15% w / w to 25% w / w, preferably 20% w / w of the mass of the prosthesis, and the collagen layer - from 20% w / w to 40% w / w, preferably 30% w / w of the mass of the prosthesis.

Implantable medical devices have a zone of high in vivo stability adjacent to a zone of relatively low in vivo stability, such that when these medical devices are implanted in a host, the zone of low in vivo stability degrades first, allowing the formation of a relatively intact band of high in vivo stability, a separate segment small enough to pass harmlessly from the host.

A ureteral stent and a manufacturing method of a ureteral stent are applied to the technical field of medical instruments, to effectively reduce ureteral stent failure in fluid guiding. The ureteral stent comprises an inner structure (200), and an outer structure (100) sleeved on the inner structure (200), wherein the outer structure (100) is a tube-shaped structure, and the outer structure (100) is made from a first wire (110). The ureteral stent can effectively reduce ureteral stent failure in fluid guiding.

An implant 1 comprises a tubular interior section 2 for implantation into a patient and an exterior section 3 connected to the interior section 2. A surface of the exterior section 3 comprises a three-dimensional porous structure 13 at its inner circumference.

A stent is disclosed that is configured to maintain patency of the prostatic urethra despite an enlarged prostate. The stent can include a handle that, in an undeflected position, is disposed outside of the flow path of the stent. When the handle is pulled, the handle can deflect to generally aligned with a central axis of the stent. A capture device is disclosed that includes a tapered tip to navigate a working channel of a delivery device and a hook that can capture the stent handle and be moved into a tube to retain the stent handle to facilitate maneuvering of the stent in and out of the working channel of the delivery device. A loading adapter with a tapered port is disclosed that can be disposed on the delivery device to distribute compressive forces applied by the port on the stent during loading into the working channel.

Medical implants that include a containment layer surrounding, or surrounded by, a biodegradable medical device provide the benefit that pieces formed during degradation of the medical device are held within a constrained place and thus do not causes injury to a hosts.

Embodiments of a Urological implant include an implant with an elongated body having a longitudinal axis. Optionally longitudinal ribs symmetrically oppose each other and are connected to elongated body. The longitudinal ribs are optionally elastically shiftable between a collapsed state and an expanded state relative to the spinal longitudinal axis, in order to retract or / and support periurethral tissue. Optionally the system includes an implant extraction handle. The extraction handle is optionally positioned proximally to the elongated body and connected to the longitudinal rib and subject to a pulling force to facilitate and / or force approximation of the longitudinal supports to the longitudinal axis. In some embodiments, an implant body includes longitudinally spaced arched members, interconnected via arch ends sequentially along a length of a first and second longitudinal rib. Optionally the arched members are elastically bendable to facilitate elastic contractibility of the implant body under a transverse compressive force.

A delivery system for chemotherapy, biologics, and / or drugs includes a series of implantable beads, each bead of the series of implantable beads having a bead core through which a central channel passes. The bead core contains one or more of a chemotherapy agent, a biologic, and a drug. The delivery system further includes a wire configured for guiding each bead, individually or as a group held together by a water-soluble coating, into a target organ, the wire passing through the central channel of each bead while each of the series of implantable beads is positioned in its entirety in the target organ via the wire. The target organ includes a bladder, a ureter, or a kidney. The chemotherapy agent, biologic, and drug include a chemotherapy powder that is effective for treating cancer mixed with a dissolvable compound. Cancer includes urothelial cancer or bladder cancer.

A percutaneous urinary catheter configured to be deployed in a urinary tract, including: (a) a proximal portion; and (b) a distal portion including a retention portion configured to be deployed in a kidney and / or a renal pelvis, the retention portion including one or more drainage holes leading to one or more lumen(s) within the proximal portion, wherein the retention portion, when deployed, defines a three-dimensional shape sized and positioned to maintain patency of fluid flow between the kidney and / or renal pelvis and a proximal end of the catheter by inhibiting mucosal tissue from appreciably occluding the one or more drainage holes when negative pressure is applied through the catheter.

A stent comprising a tubular member, a lumen extending through the tubular member, a first retention structure and a second retention structure at opposite ends of the tubular member. The first retention structure comprises multiple coils and a removable anti-coiling material over the multiple coils of the first retention structure to present the multiple coils as an elongated extension of the tubular member, whereupon removal of the removable anti-coiling material at least one of the multiple coils of the first retention structure is presented and any excess coils can be trimmed.

A drainage stent delivery system is disclosed. The drainage stent delivery system includes a catheter body, a stent member, and a coupling member. In some embodiments the coupling member can include keyed connectors having a non-round shape to facilitate a 1:1 rotation ration of the catheter body and the stent member. In another embodiment, the coupling member can include a telescoping connector having an inner tube and a release wire disposed through the inner tube. A distal portion of the release wire has an outer diameter greater than an inner diameter of the inner tube such that the telescoping connector can be displace by the release wire. In another embodiment, the stent member includes a proximal retention member having arms that are outwardly extendable.

A guidewire for use with ureteral stents has an elongated shape with a proximal end and a distal end. The guidewire has indicia along the proximal end to indicate the length of the guidewire that was introduced into the patient. Based on the indicia or the visual inspection, a physician can select the appropriately sized stent to place in the patient.

A stent configured to maintain patency of the prostatic urethra despite prostatic hyperplasia is disclosed. The stent may include a handle disposed outside the stent flow path in an undeflected position. When the handle is pulled, the handle may deflect to generally coincide with the central axis of the stent. A capturing device is disclosed that includes a tapered tip for moving through the working channel of a delivery device and a hook that can capture the stent handle and move within the tube to hold the stent handle and facilitate manipulation of the stent in and out of the working channel of the delivery device. A loading adapter with a tapered port that can be positioned on a delivery device to distribute compressive forces exerted by the stent port during loading into the working channel is disclosed.

The present invention relates to a medical device (100) for use as a ureteral stent, a biliary stent or a urinary catheter in a human or animal body. The medical device (100) comprises a hollow device body (101) having at least one body lumen (102), an inner body surface (105) and an outer body surface (106), wherein the inner body surface (105) delimits the at least one body lumen (102). The medical device (100) further comprises at least one array (110) of microstructures (111) located on the inner body surface (105) and / or the outer body surface (106) and configured to locally increase fluid-induced shear stress acting on the device body (101) in use of the medical device (100) in response to applying an acoustic field to the medical device (100). The invention further relates to a medical system comprising such as a medical device and an activation device configured to be positioned externally of a human or animal body, wherein the activation device comprises at least one sound transducer configured to generate an acoustic field for application from externally of the human or animal body to the medical device. The invention further relates to as to a method of acoustically activating such a medical device during use in a human or animal body, in particular for cleaning purposes and / or mass transport.

A passive stent removal device, system and method using a series of capturing steps to grasp a stent smoothly and consistently for removal.