19 results about "Hydrophilic matrix" patented technology

Provided is a grease composition containing a base oil (A), hydrophilic nanofibers (B) having a roughness (d) of 1 nm to 500 nm, and particles (C) having a structure in which the hydrophilic nanofibers (B) are one or more types selected from the group consisting of cellulose nanofibers (B1) and modified cellulose nanofibers (B2), the particles (C) having a hydrophobic group on the outermost surface of the hydrophilic matrix structure, and having a hydrophobic group on the outermost surface of the hydrophilic matrix structure. In the grease composition, the average particle diameter of the particles (C) is 1 nm to 500 nm, and the grease composition has an appropriate oil separation degree and excellent water resistance despite the use of hydrophilic nanofibers.

The present disclosure allows for an anaerobic biofilm also known as a beneficial biofilm, to be grown on a hydrophilic substrate surface and contained within the varied surface and surface-accessible interior of the substrate. This allows for the anaerobic biofilm to remain intact and functional while being exposed to an aerobic environment. The present disclosure further allows for the constituent microbes to interact with an oxygen-rich surrounding without perishing. The present disclosure allows anaerobic biofilm constituent microbes to exist side-by-side with aerobic biofilm constituent microbes and employ various mechanisms to starve or eliminate unhealthy biofilms and sessile and free-floating unwanted microbes, and / or deliver substances to soil to improve soil health or to the body to assist in repair of injuries such as microbial infections, lesions, tumors, cuts, abrasions, burns, and nerve damage.

The invention relates to the technical field of high-molecular separation membranes, and particularly discloses a high-temperature-resistant and high-pressure-resistant moisture-permeable membrane which comprises the following raw materials: a hydrophilic matrix polymer, a skeleton polymer, a hydrophilic filler and a cross-linking agent. A covalent cross-linked network for permanently locking a high-strength skeleton phase and a high-moisture-permeability channel phase is formed by constructing a nano bicontinuous phase separation structure formed by polybenzimidazole and carboxyl-functionalized sulfonated polyetheretherketone and then through a high-temperature in-situ cross-linking reaction. The moisture-permeable film prepared by the invention has excellent comprehensive performance, can realize efficient selective permeation of water vapor under harsh working conditions of 250 DEG C and 3.0 MPa, keeps ultrahigh mechanical strength and long-term operation stability, and effectively solves the problem that the moisture-permeable film in the prior art cannot give consideration to both high temperature and high pressure resistance and high separation performance.

The invention belongs to the technical field of surfactants for foam drilling fluids in petroleum and natural gas development, and relates to a water-based functional gemini surfactant and a preparation method thereof. The preparation method comprises the following steps: S1, mixing a bio-based hydrophilic matrix with a first alcohol solvent, adding a silane pre-activator, and carrying out a nucleophilic transesterification reaction; s2, mixing the pre-activated bio-based hydrophilic matrix, bio-based polyoxyethylene ether glycidyl ether and a second alcohol solvent, adding a supported composite catalyst, and carrying out a nucleophilic ring-opening reaction; and S3, dissolving the bio-based gemini surfactant skeleton in a polar solvent, firstly adding a first sulfonating agent to carry out substitution sulfonation reaction at low temperature, then heating to a certain temperature, and adding a second sulfonating agent to carry out nucleophilic addition sulfonation reaction. The prepared surfactant can remarkably improve the high characteristic value stability of the foam drilling fluid, and is especially suitable for extreme industrial application scenes such as high-temperature deep wells and high-salt oil reservoirs.

A propagation stopper comprising a radiated hydrophilic matrix body comprising a growth medium with bound organic fibers, the matrix body being rewettable and having a moisture content of less than about 20% by weight based on the total weight of the body, as measured according to ASTM Test Method D2216, and being sterile, as measured according to ASTM Test Method D2216, and having a moisture content of less than about 20% by weight based on the total weight of the body. The number of aerobic bacteria measured by the number 4833-1 of the ISO test method is lt; 10 cfu / g.

This invention belongs to the field of hydrogel technology, specifically relating to an organosilicon-reinforced high-strength and tough hydrogel, its preparation method, and its applications. The organosilicon-reinforced high-strength and tough hydrogel and its preparation method involve first preparing a hydrophobic amino-functionalized polysiloxane (APSi) using aminosilane as a raw material. Then, APSi is mixed with polymerizable monoacids and hydrophilic matrix monomers. Uniform dispersion and strong interfacial bonding of the organosilicon are achieved through salt-forming ion interactions. The high-strength and tough hydrogel is obtained through photo-initiated or thermally-initiated polymerization. This invention overcomes the technical bottleneck of limited improvement in the strength and toughness of hydrogels by traditional methods, completely solving the industry problems of poor mechanical properties, weak puncture resistance, poor tear resistance, uneven organosilicon dispersion, and weak interfacial bonding in traditional hydrogels. The resulting hydrogel exhibits high tensile strength, good toughness, excellent puncture and tear resistance, fatigue resistance, and strong stability. The preparation process is mild and simple, and it can be widely applied in high-end fields such as biomedicine, flexible electronics, soft robotics, and smart wearables.

The invention provides a tissue phase homogenizing agent and a preparation method and application thereof, and belongs to the technical field of biological tissue engineering, the homogenizing agent is composed of hydrophilic matrixes (glucose, polyglycerol, poloxamer F127 and polyvinyl alcohol), functional additives (mannose, N-acetylcysteine, sodium hyaluronate and polyethylene glycol) and ultrapure water, and the pH value is 7.0 + / -0.2. Hydrophilic groups and water molecules form a hydrogen bond network, a continuous hydration layer is constructed on a phase interface, phase domain fusion, refractive index homogenization and molecular ordering are achieved, the problem of biological tissue phase homogenization is solved, tissue light transmittance can be improved, the swelling ratio can be stabilized, and the hydrogel has cell proliferation promoting activity and is suitable for tissue transplantation operation and bioengineering tissue preservation.

The invention relates to sustained release oral medicinal product containing tolperisone, that contains tolperisone hydrochloride, betaine hydrochloride and a hydrophilic matrix-forming material and which medicinal product releases at least 80% of the tolperisone hydrochloride active ingredient within 6 hours. Furthermore, the invention relates to the manufacture of the above medicinal product and to its use.

The invention belongs to the technical field of functional food packaging materials, and discloses an intelligent composite film for food freshness monitoring and preservation as well as a preparation method and application of the intelligent composite film. According to the composite membrane, carboxymethyl chitosan serves as a matrix, curcumin (Cur) is stabilized in a hydrophobic micro-area of waterborne polyurethane in a physical embedding mode to form a WPU-Cur dispersion, cellulose nanocrystals (CNC) are introduced to serve as a reinforcing agent, and the technical scheme that Cur is physically packaged through WPU and a ternary composite system is constructed in cooperation with CNC / CMCS is created for the first time. The technical problem that Cur is unstable in a hydrophilic matrix is solved. The obtained composite film has excellent mechanical property, high barrier property, remarkable antioxidant and antibacterial activity (active preservation) and sensitive color response (intelligent indication) to pH / amine gas, and can effectively prolong the shelf life and visually monitor the freshness in real time through color change when being applied to packaging of food (such as meat, aquatic products and dairy products).

The present invention relates to a coated formulation. The formulation contains silodosin, a sustained-release material, and an antioxidant. The sustained-release material is selected from hydrophilic matrix sustained-release materials, and the coating contains a plasticizer. The coated formulation of the present invention can effectively reduce the instability caused by the incompatibility between the silodosin and the sustained-release material, and the coating can further inhibit the continuous reduction of the content of the antioxidant.

Described herein are solid oral sustained release Kv7.2 / 7.3 potassium channel activator formulations for oral administration. In certain aspects, the formulations have a specific dissolution rate profile and / or a specific peak-to-valley ratio. In one aspect, the formulation comprises an intragranular portion comprising a Kv7.2 / 7.3 potassium channel activator, a hydrophilic matrix polymer, a filler, and a binder; and an extragranular fraction comprising a sustained release polymer, optionally a hydrophilic matrix polymer, and a lubricant. The Kv7.2 / 7.3 potassium channel activator has a formula I or a pharmaceutically acceptable salt of the Kv7.2 / 7.3 potassium channel activator. I

The invention discloses a concrete curing coating capable of forming a Janus structure and a preparation method thereof. Hydrophobic components with interface migration tropism are spontaneously enriched on the outer side of a matrix in the film forming process, and a continuous wettability gradient, namely a Janus structure, is formed by the hydrophobic components and the relatively hydrophilic matrix on the inner side. According to the structure, based on the difference between capillary force and surface energy, water molecules in the external environment can permeate inwards, meanwhile, water vapor is prevented from being evaporated outwards, and therefore one-way water retention is achieved. The coating can quickly form a film after being sprayed, effectively delays evaporation of water in concrete, and is especially suitable for concrete structure maintenance under harsh conditions such as plateau, high temperature and strong wind drying.

The application belongs to the technical field of new energy and energy-saving materials, and particularly relates to a sun-proof cooling material with radiation cooling and moisture absorption and volatilization effects, and a preparation method and application thereof. The sun-proof cooling material is prepared by the following steps: adding an organic polymer, a sunscreen agent and inorganic micro-nano particles into an organic solvent to obtain a mixed solution, spraying the mixed solution on a breathable layer I to dry to form a heat dissipation layer, adding a moisture absorbent into a precursor solution prepared from a polymer hydrophilic matrix and deionized water, and freeze-drying the precursor solution to obtain a gel film with moisture absorption function, laminating the heat dissipation layer, the breathable layer I, the gel film and a breathable layer II in sequence to obtain the sun-proof cooling material with the radiation cooling and moisture absorption and volatilization effects. The sun-proof cooling material can reflect most of the sunlight, emit heat outward by emitting mid-far infrared rays, achieve heat dissipation, and realize low-cost and energy-free cooling and sun-proofing by guiding moisture through the breathable layer and cooperating with the heat dissipation layer. The sun-proof cooling material is simple to prepare and can be produced on a large scale.

The invention discloses a preparation method of a genipin cross-linked synergistic nanofiber reinforced carboxymethyl chitosan antifogging preservative film, which comprises the following steps: (1) dissolving carboxymethyl chitosan in deionized water, sequentially adding gelatin, genipin, glycerol and carboxylated cellulose nanofiber, stirring in a water bath, and standing for defoaming to obtain a mixed film solution; and (2) uniformly coating the mixed film solution in a tape casting manner, performing vacuum drying, and balancing to obtain the carboxymethyl chitosan antifogging preservative film. In a gelatin and glycerol system, carboxymethyl chitosan is taken as a main hydrophilic matrix, natural cross-linking agents genipin and carboxylated cellulose nanofibers are introduced, and finally, the high-performance carboxymethyl chitosan-based antifogging preservative film is prepared through a tape casting method, and the antifogging preservative film is good in performance. The invention also discloses an application of the carboxymethyl chitosan antifogging preservative film in preservation of fresh fruits and vegetables.

A composition for UV absorption has a superior UV absorption function, and is superior in dispersibility while absorbing, in particular, UVA (wavelength: 315 to 380 nm) and UVB (wavelength: 280 to 315 nm). The composition for UV absorption includes a carbon-based quantum dot, an aqueous solvent, a surfactant, and an oily base. Alternatively, the composition for UV absorption includes a carbon-based quantum dot, an aqueous solvent, and a hydrophilic base. A method for manufacturing the composition for UV absorption includes mixing an aqueous dispersion containing a carbon-based quantum dot and an aqueous solvent, a surfactant, and an oily base. A method for manufacturing the composition for UV absorption includes mixing an aqueous dispersion containing a carbon-based quantum dot and an aqueous solvent, and a hydrophilic base.

The invention relates to a sustained release pharmaceutical composition comprising a tablet core comprising a therapeutically effective amount of a compound selected from Group 1, or a pharmaceutically acceptable salt thereof, an insoluble matrix forming release agent and a hydrophilic matrix forming release agent.

The invention relates to the technical field of high polymer material compositions, and discloses a high-strength low-water-absorbability polyamide engineering plastic and a preparation method thereof.The preparation method comprises the steps that a non-monotonic temperature path is set in a double-screw extruder, and under the melting point of a polyamide matrix, high shear is applied to enable a hydrophobic phase to be forcibly coated on the surfaces of solid polyamide particles, constructing a core-shell intermediate phase state; then heating to melt a polyamide core part, triggering in-situ grafting of a compatilizer preset on an interface, and chemically fixing the intermediate phase state; a controlled path of a subsequent chemical reaction is restrained through physical shaping, the constructed ordered hydrophobic network phase can form effective physical enclosure for a hydrophilic matrix, and an efficient stress transfer path is established, so that the strength and toughness of the material are synergistically improved while low water absorption is realized.

The invention provides a hirudin cataplasm patch and a preparation method thereof, and belongs to the technical field of cataplasm patches, the hirudin cataplasm patch is composed of lining cloth, gel paste and an anti-sticking isolating membrane, the gel paste comprises active components and a nano particle doped matrix, the active components comprise hirudin and an auxiliary active composition, the nano particle doped matrix comprises a nano particle doped matrix, and the anti-sticking isolating membrane comprises a nano particle doped matrix and a nano particle doped matrix. Wherein the auxiliary active composition comprises the following components in parts by weight: 1.4-1.6 parts of a traditional Chinese medicine extract, 0.2-0.3 part of resveratrol, 0.4-0.6 part of a stable compound and 2-3 parts of pearl powder, the traditional Chinese medicine extract is prepared from pseudo-ginseng, astragalus membranaceus and rhodiola rosea through water extraction, and the nanoparticle doped matrix is prepared from ion modified lignin nanoparticles doped with a hydrophilic matrix glue solution. The hirudin cataplasm prepared by the invention not only has a good whitening effect, but also can keep a relatively high whitening effect after being repeatedly used for multiple times, so that the use cost is reduced, the full release of effective components can be ensured, and the hirudin cataplasm is suitable for the conditioning requirements of long-term chronic whitening and skin care.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and discloses a traditional Chinese medicine patch for treating polycystic ovarian syndrome, a medicine layer of the patch adopts a double-layer structure, and comprises a medicine substrate storage layer far away from a skin application side and an enzymolysis catalysis and sequential release layer facing the skin application side. The drug substrate storage layer comprises a hydrophobic matrix and a traditional Chinese medicine prodrug; the enzymolysis catalysis and sequential release layer comprises a hydrophilic matrix, a biological enzyme source, an osmotic pressure regulator and a pH-sensitive sequential release unit. During application, the application agent drives the prodrug to migrate by utilizing osmotic pressure, and is subjected to in-situ enzymolysis on the skin surface to form an active product which is easy for transdermal absorption; the acidic material generated by the enzymatic reaction further triggers the pH sensitive unit to release the second drug. The transdermal absorption rate of macromolecular traditional Chinese medicine ingredients is improved through in-situ conversion, programmed sequential release of the two medicines is achieved, the synergistic effect is enhanced, and meanwhile the good storage stability of the product is guaranteed through a double-layer physical isolation structure.