8 results about "Hydrophilic matrix" patented technology

The present disclosure allows for an anaerobic biofilm also known as a beneficial biofilm, to be grown on a hydrophilic substrate surface and contained within the varied surface and surface-accessible interior of the substrate. This allows for the anaerobic biofilm to remain intact and functional while being exposed to an aerobic environment. The present disclosure further allows for the constituent microbes to interact with an oxygen-rich surrounding without perishing. The present disclosure allows anaerobic biofilm constituent microbes to exist side-by-side with aerobic biofilm constituent microbes and employ various mechanisms to starve or eliminate unhealthy biofilms and sessile and free-floating unwanted microbes, and / or deliver substances to soil to improve soil health or to the body to assist in repair of injuries such as microbial infections, lesions, tumors, cuts, abrasions, burns, and nerve damage.

The invention relates to the technical field of high-molecular separation membranes, and particularly discloses a high-temperature-resistant and high-pressure-resistant moisture-permeable membrane which comprises the following raw materials: a hydrophilic matrix polymer, a skeleton polymer, a hydrophilic filler and a cross-linking agent. A covalent cross-linked network for permanently locking a high-strength skeleton phase and a high-moisture-permeability channel phase is formed by constructing a nano bicontinuous phase separation structure formed by polybenzimidazole and carboxyl-functionalized sulfonated polyetheretherketone and then through a high-temperature in-situ cross-linking reaction. The moisture-permeable film prepared by the invention has excellent comprehensive performance, can realize efficient selective permeation of water vapor under harsh working conditions of 250 DEG C and 3.0 MPa, keeps ultrahigh mechanical strength and long-term operation stability, and effectively solves the problem that the moisture-permeable film in the prior art cannot give consideration to both high temperature and high pressure resistance and high separation performance.

This invention belongs to the field of hydrogel technology, specifically relating to an organosilicon-reinforced high-strength and tough hydrogel, its preparation method, and its applications. The organosilicon-reinforced high-strength and tough hydrogel and its preparation method involve first preparing a hydrophobic amino-functionalized polysiloxane (APSi) using aminosilane as a raw material. Then, APSi is mixed with polymerizable monoacids and hydrophilic matrix monomers. Uniform dispersion and strong interfacial bonding of the organosilicon are achieved through salt-forming ion interactions. The high-strength and tough hydrogel is obtained through photo-initiated or thermally-initiated polymerization. This invention overcomes the technical bottleneck of limited improvement in the strength and toughness of hydrogels by traditional methods, completely solving the industry problems of poor mechanical properties, weak puncture resistance, poor tear resistance, uneven organosilicon dispersion, and weak interfacial bonding in traditional hydrogels. The resulting hydrogel exhibits high tensile strength, good toughness, excellent puncture and tear resistance, fatigue resistance, and strong stability. The preparation process is mild and simple, and it can be widely applied in high-end fields such as biomedicine, flexible electronics, soft robotics, and smart wearables.

The invention relates to sustained release oral medicinal product containing tolperisone, that contains tolperisone hydrochloride, betaine hydrochloride and a hydrophilic matrix-forming material and which medicinal product releases at least 80% of the tolperisone hydrochloride active ingredient within 6 hours. Furthermore, the invention relates to the manufacture of the above medicinal product and to its use.

Described herein are solid oral sustained release Kv7.2 / 7.3 potassium channel activator formulations for oral administration. In certain aspects, the formulations have a specific dissolution rate profile and / or a specific peak-to-valley ratio. In one aspect, the formulation comprises an intragranular portion comprising a Kv7.2 / 7.3 potassium channel activator, a hydrophilic matrix polymer, a filler, and a binder; and an extragranular fraction comprising a sustained release polymer, optionally a hydrophilic matrix polymer, and a lubricant. The Kv7.2 / 7.3 potassium channel activator has a formula I or a pharmaceutically acceptable salt of the Kv7.2 / 7.3 potassium channel activator. I

The invention discloses a concrete curing coating capable of forming a Janus structure and a preparation method thereof. Hydrophobic components with interface migration tropism are spontaneously enriched on the outer side of a matrix in the film forming process, and a continuous wettability gradient, namely a Janus structure, is formed by the hydrophobic components and the relatively hydrophilic matrix on the inner side. According to the structure, based on the difference between capillary force and surface energy, water molecules in the external environment can permeate inwards, meanwhile, water vapor is prevented from being evaporated outwards, and therefore one-way water retention is achieved. The coating can quickly form a film after being sprayed, effectively delays evaporation of water in concrete, and is especially suitable for concrete structure maintenance under harsh conditions such as plateau, high temperature and strong wind drying.

The invention discloses a preparation method of a genipin cross-linked synergistic nanofiber reinforced carboxymethyl chitosan antifogging preservative film, which comprises the following steps: (1) dissolving carboxymethyl chitosan in deionized water, sequentially adding gelatin, genipin, glycerol and carboxylated cellulose nanofiber, stirring in a water bath, and standing for defoaming to obtain a mixed film solution; and (2) uniformly coating the mixed film solution in a tape casting manner, performing vacuum drying, and balancing to obtain the carboxymethyl chitosan antifogging preservative film. In a gelatin and glycerol system, carboxymethyl chitosan is taken as a main hydrophilic matrix, natural cross-linking agents genipin and carboxylated cellulose nanofibers are introduced, and finally, the high-performance carboxymethyl chitosan-based antifogging preservative film is prepared through a tape casting method, and the antifogging preservative film is good in performance. The invention also discloses an application of the carboxymethyl chitosan antifogging preservative film in preservation of fresh fruits and vegetables.

The invention relates to a sustained release pharmaceutical composition comprising a tablet core comprising a therapeutically effective amount of a compound selected from Group 1, or a pharmaceutically acceptable salt thereof, an insoluble matrix forming release agent and a hydrophilic matrix forming release agent.