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163 results about "Prostate gland" patented technology

Prostate gland: A gland in the male reproductive system that is located just below the bladder. It surrounds part of the urethra, the canal that empties the bladder. ... The prostate gland helps to control urination, and it forms part of the content of semen.

Prostate stent and system thereof

The invention provides a prostate stent which comprises a stent body and a pull rope, the stent body is made of shape memory alloy and comprises at least three supporting ridges extending in the longitudinal direction, and the far ends of every two adjacent supporting ridges are connected through a far side connecting part; the near ends of every two adjacent supporting edges are connected through a near side connecting part. The far end of each pull rope is independently connected with one near side connecting part, the near ends of all the pull ropes are gathered at the far end of the same traction rope, and the support body is folded through the pull ropes.
Owner:ZHEJIANG YIGAO MEDICAL TECH CO LTD

Solabegron zwitterion and uses thereof

This application relates to solabegron zwitterion useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to pharmaceutical compositions and methods of treatment utilizing the solabegron zwitterion for treating lower urinary tract symptoms. This application also relates to methods of preparing solabegron hydrochloride from the solabegron zwitterion.
Owner:B3AR THERAPEUTICS INC

Prostate puncture ultrasonic probe fixing and adjusting device

The utility model discloses a prostate puncture ultrasonic probe fixing and adjusting device, which relates to the field of adjusting devices and comprises a probe rotating and fixing mechanism used for mounting an ultrasonic probe and a multi-axis fine adjustment mechanism connected with the probe rotating and fixing mechanism and used for adjusting the ultrasonic probe. The multi-axis fine adjustment mechanism comprises an axial adjustment assembly, a ball head adjustment assembly and a fixing mechanism installation assembly, and the axial adjustment assembly comprises a Z-axis adjustment component and an X-axis and Y-axis adjustment component installed on the Z-axis adjustment component. By arranging the multi-axis fine adjustment mechanism and the probe rotating and fixing mechanism, the existing structure is optimized, the probe rotating and fixing mechanism uses a probe locking nut to firmly press a probe and the probe rotating and fixing mechanism together, and the problems that in original installation, a screw needs to be screwed manually for fixation, and the loosening risk exists are solved. And the part without sharp protrusion does not scratch a patient during use.
Owner:PUNCTURE (SHANGHAI) ROBOTIC CO LTD

Device and a system for voiding dysfunction diagnosis

The present invention is related to a device and a system for voiding dysfunction diagnosis. By detecting a vibration signal generated by the urine from a patient who suffers from urinary dysfunction, the present invention could efficiently and accurately detect and monitor the condition of the patient. The present invention can be introduced to actual clinical applications achieving continuous monitoring urination status for the patient for home care. The present invention could also provide urinary medication efficiency or urinary status of the patient before or after prostate surgery.
Owner:FENG CHIA UNIVERSITY

A urethral catheter and device with conductive structures

ActiveCN116196083BBalloon catheterMulti-lumen catheterUrethraHuman bladder
The application is a urethral catheter with conductive structure, which comprises a flexible catheter, the flexible catheter enters the human bladder through the urethra, the outer surface of the flexible catheter is partially provided with a conductive structure, the conductive structure is arranged at the prostate part of the outer distal end of the flexible catheter to assist freezing and electric ablation, the flexible catheter is internally provided with a liquid guide channel and a liquid guide opening is arranged at the distal end of the flexible catheter, the urethral catheter has a temperature protection effect, a temperature protection channel is divided into a liquid inlet channel and a liquid outlet channel by an inner sleeve and an outer sleeve, a surface electrode on the outer wall of the inner sleeve is connected to the circuit of a host, and the conductive structure only conducts electricity and does not have an electrochemical reaction. The application is used for cooperating to complete electric effect or electric ablation diagnosis and treatment effect and freezing, radio frequency and microwave and other thermal ablation, can avoid cold and hot damage or electric damage to the urethra or the prostate, has a temperature adjusting function and a simple structure and is easy to adjust and control.
Owner:MEDINUX (TIANJIN) TECH CO LTD

Delivery systems for control of bleeding in transurethral prostatectomy

ActiveUS12508171B2Balloon catheterSurgeryTransurethral prostatectomyBiocompatibility
The present disclosure relates to a gastrointestinal delivery device of a chitosan dressing, where the delivery device is capable of stop bleeding, in particular in connection with TURP procedures. The delivery device may be used in all gastrointestinal bleeding applications and can be used with a biocompatible, foldable, thin profile, chitosan dressing. Various aspects of the device and its uses are provided herein.
Owner:TRICOL BIOMEDICAL INC +1

Systems and methods for regulating organ and / or tumor growth rates, function, and / or development

ActiveUS12369859B2Ultrasound therapyElectrotherapyNerve structureProstate tumours
A system for controlled neuromodulation procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Systems and methods for imaging, monitoring, stimulating, and / or ablating neurological structures coupled to one or more organs of the lower urinary tract (LUT) are disclosed. Such processes may be used to alter the hormonal secretions from one or more organs, to modulate the growth of an organ, alter the growth rate or rate of perineural invasion of a tumor, or the like. In particular such processes may be used to slow, halt and / or reverse the growth of a prostate gland or a prostate tumor.
Owner:AUTONOMIX MEDICAL INC

Prostate massager

ActiveCN309939635SOncologyInternal medicine
1. Name of the product in this design: Prostate Massager. 2. Purpose of this design: A massager for massaging the prostate. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.
Owner:TAIYUAN IRON & STEEL (GRP) CO LTD GENERAL HOSPITAL

Systems and methods for regulating organ and / or tumor growth rates, function, and / or development

PendingUS20250325232A1Ultrasound therapyElectrotherapyNerve structureProstate tumours
A system for controlled neuromodulation procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Systems and methods for imaging, monitoring, stimulating, and / or ablating neurological structures coupled to one or more organs of the lower urinary tract (LUT) are disclosed. Such processes may be used to alter the hormonal secretions from one or more organs, to modulate the growth of an organ, alter the growth rate or rate of perineural invasion of a tumor, or the like. In particular such processes may be used to slow, halt and / or reverse the growth of a prostate gland or a prostate tumor.
Owner:AUTONOMIX MEDICAL INC

Male orgasm enhancement device and method

In some embodiments, the present invention provides a device wherein the device comprises a muscle stimulator configured to be attached to perineal skin surfaces and other skin surfaces of a subject who wishes enhanced orgasm wherein the muscle stimulator comprises electrodes configured to be attached to the perineal skin surfaces and other skin surfaces of a subject who wishes enhanced orgasm. The electrodes are configured to percutaneously send electrical or magnetic impacts to globular cavernous muscles and / or seminal vesicles and / or prostate of a subject, wherein the percutaneously sent impacts are configured to enhance and / or prolong male orgasm.
Owner:VIRILITY MEDICAL LTD

Ablation device and prostate tissue ablation system

The invention provides an ablation device and a prostate tissue ablation system.The ablation tissue comprises a head electrode assembly, a needle electrode assembly and a handle assembly, the head electrode assembly comprises a head end main body and an outer tube which are connected with each other, the head end main body is arranged at the far end of the outer tube, a head electrode is arranged at the far end of the head end main body, and the needle electrode assembly is arranged on the outer tube. A needle electrode channel is arranged in the outer tube, the needle electrode assembly is contained in the needle electrode channel, the needle electrode assembly comprises at least one needle electrode, and the needle electrode assembly extends out of the side face of the ablation device based on operation on the handle assembly. According to the embodiment of the invention, the interventional operation of entering the urethra through a natural orifice and operating under a visual working condition and adopting an irreversible electroporation steep pulse electric field with tissue selectivity can be realized, so that the operation efficiency and the operation safety and effectiveness are greatly improved.
Owner:HUNAN ENDOVASCULAR DEVICES CO LTD

Method for imaging support of transurethral prostate resection and TURP system

A method and a system for navigation and / or control support for transurethral prostate resection, the method including: analyzing endoscopic images provided by a resectoscope and / or additional sensory data from within the resectoscope during TURP for one or more of several options, and at least one of: automatically disabling HF current to the resection electrode under several different outcomes of the analyzing, and outputting visual and / or acoustic information to an operator performing the TURP. The information including at least one of: a visual indication of an anatomical landmark inside and / or outside of the endoscopic image, a visual indication of a distance of the resection electrode to an anatomical landmark, and a visual or acoustic warning signal when the resection electrode comes closer than a predetermined allowable distance to one or more of the bladder neck, the verumontanum and the internal and / or external sphincter muscles.
Owner:OLYMPUS WINTER & IBE GMBH

Thermal vapor treatment device

1. The name of the design product: hot steam treatment equipment. 2. The use of the design product: used with the prostate hot steam treatment instrument to relieve symptoms and obstruction related to benign prostatic hyperplasia (BPH). 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.
Owner:海汛医疗科技(苏州)有限公司

In-vitro prostate pathological tissue positioning identification and sampling device

The utility model discloses an in-vitro prostate pathological tissue positioning identification and sampling device, which relates to the technical field of medical instruments and comprises a support component, a positioning guide component and a plurality of positioning needles. The support assembly comprises a supporting plate and a positioning column, and the positioning column is used for penetrating through the urethra of the prostate to fix the prostate; the positioning and guiding assembly is installed on the support assembly, and scales used for positioning the tumor position in the prostate body are arranged on the positioning and guiding assembly; and the plurality of positioning needles are used for positioning and identifying focuses in the prostate body. Through the arrangement, the preoperative mpMRI image of a patient and a 3D reconstructed digital model can be used as input, and the position of a tumor in a gland can be accurately positioned again under the condition that the prostate tissue is in vitro through the assistance of the in-vitro prostate pathological tissue positioning identifier and the sampling device; therefore, the target tumor tissue can be quickly and accurately taken out from the in-vitro prostate.
Owner:THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIV

Heat dissipation gel for prostate protection cushion and preparation method of heat dissipation gel

The invention discloses a heat dissipation gel for a prostate protection cushion and a preparation method thereof in the technical field of heat dissipation gels, and the heat dissipation gel comprises the following components in parts by weight: 3-5 parts of nano-silver boron nitride, 14-16 parts of poly (1, 4-butanediol adipate), 22-26 parts of isophorone diisocyanate, 10-16 parts of toluene, 3-mercapto-1, 4-butanediol adipate, 2-6 parts of 3-mercapto-1, 4-butanediol adipate, 2-6 parts of 3-mercapto-1, 4-butanediol adipate, 2-6 parts of 3-mercapto-1, 4-butanediol 2 to 3 parts of 1, 2-propylene glycol, 4 to 6 parts of perfluorohexyl ethanol and 1.2 to 1.6 parts of 1, 4-butanediol. The heat dissipation effect is improved by preparing a high-heat-conductivity modified boron nitride-polyurethane material, and meanwhile, the material is subjected to surface hydrophobic modification, so that the moisture absorption of the cushion is reduced, the perspiration ability is improved, the retention of sweat in the cushion is reduced, the air permeability is improved, and the service life of the cushion is prolonged. A disulfide bond is further introduced to form a normal-temperature dynamic repairing structure, so that the self-repairing performance of the seat cushion is improved, and the rebound effect is achieved.
Owner:FOSHAN HOSPITAL OF TCM

Fixed dose combination of flavoxate and beta-3 adrenergic receptor agonists, and formulations and manufacturing processes thereof

PCT designated stageWO2026064392A1Organic active ingredientsPill deliveryFlavoxateAdrenergic
The present disclosure provides for fixed-dose combination formulations comprising flavoxate or a pharmaceutically acceptable salt thereof and at least one β3-adrenergic receptor agonist, along with methods of making and using the same to treat symptoms associated with prostate, bladder, urinary tract, and pelvic conditions.
Owner:FLAVOSTAR LLC

Application of methylation level of aromatase gene CYP19A1 in evaluation of benign prostatic hyperplasia progress degree

The invention provides an application of an aromatase gene CYP19A1 methylation level in evaluation of benign prostatic hyperplasia progress degree. The traditional Chinese medicine composition is used for treating benign prostatic hyperplasia patients from early progression; whether methylation and demethylation occur in CpG islands in promoter regions of aromatase genes CYP19A1 in prostate tissues of bladder cancer patients and elderly benign prostatic hyperplasia patients who are age-matched and subjected to radical bladder resection and prostatic resection are detected and analyzed, and whether methylation and demethylation occur in the CpG islands in the promoter regions of the aromatase genes CYP19A1 in the prostate tissues or not is judged; according to the present invention, the CYP19A1 gene methylation level is low and the CYP19A1 gene demethylation level is high in the prostate tissue of the early stage progression BPH patient, and the aromatase expression of the coding protein of the CYP19A1 gene is up-regulated, such that the aromatase gene CYP19A1 methylation change is related to the benign prostatic hyperplasia progress, and the new thought is provided for the risk stratification of the benign prostatic hyperplasia disease;
Owner:PEKING UNIVERSITY FIRST HOSPITAL (PEKING UNIVERSITY FIRST CLINICAL MEDICAL COLLEGE)

Urinary surgery clinical decision support method and system based on artificial intelligence

PendingCN120565051AMechanical/radiation/invasive therapiesDiagnostic signal processingBLADDER ABNORMALITYIntravesical pressure
The invention relates to the technical field of decision support, in particular to a urinary surgery clinical decision support method and system based on artificial intelligence, and the method comprises the following steps: recording the bladder volume and the pressure data in the bladder of a patient in real time by using a bladder pressure measurement catheter, calculating the bladder compliance and the curve slope change rate, and recognizing the detrusor muscle contraction abnormality type. And generating a bladder anomaly classification result. According to the method, the bladder compliance and the curve slope change rate are calculated, the abnormal detrusor contraction is recognized, the urine flow velocity descending trend, the urine flow velocity peak delay time and the recovery curve slope are extracted in combination with urine flow dynamics data, and quantitative analysis of the urinary tract obstruction degree is achieved. The accuracy of individualized operation risk assessment is enhanced by combining the prostate volume, the lesion site, the operation type suitability and the operation complication probability, the postoperative recovery cycle prediction is optimized by analyzing the bladder compliance, the urine flow rate and the detrusor muscle contraction intensity, and the refinement degree of rehabilitation management is improved.
Owner:THE FIRST PEOPLES HOSPITAL OF NANTONG

Biomarkers, kits and systems for diagnosing prostate hyperplasia secondary bladder damage

PendingCN122130952AEnsemble learningBiological testingBladder injuryUrine sample
This invention discloses a biomarker, reagent kit, and system for diagnosing bladder injury secondary to benign prostatic hyperplasia (BPH), relating to the field of biomedical detection technology. The biomarker for diagnosing bladder injury secondary to BPH is characterized in that it includes urinary DAB2 protein. This invention achieves (1) clinical applicability: accurate quantitative assessment of the degree of injury. The most significant clinical value of urinary DAB2 protein lies in its ability to transform traditional subjective bladder injury assessment into an objective quantitative indicator. (2) convenient detection: non-invasive and rapid assessment using urine samples. As a urine detection biomarker, urinary DAB2 protein completely changes the traditional bladder injury assessment's reliance on invasive or expensive examinations such as cystoscopy and CT. (3) clinical decision support: the grading diagnostic value of urinary DAB2 protein is directly translated into clinical decision support capabilities, helping to avoid the clinical dilemma of "overtreatment" or "undertreatment."
Owner:THE THIRD MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

Clinical prostate expansion device for urinary surgery

The utility model relates to the technical field of prostate expansion equipment, and discloses a urinary surgery clinical prostate expansion device which comprises a pushing pipe, an expansion pipe is installed on the outer wall of the pushing pipe, a urine guide head is installed on the outer wall of the expansion pipe, an expansion air bag is movably connected with an inner cavity of the expansion pipe in a sleeved mode, and a catheter is installed on the inner cavity of the expansion air bag. A supporting rod is movably connected with an inner cavity of the catheterization head in a sleeved mode, and a catheterization channel is formed in an inner cavity of the supporting rod. According to the clinical prostate dilation device for the urinary surgery department, the dilation tube and the dilation air bag can be supported under the action of the supporting rods arranged in the inner cavities of the pushing tube, the dilation tube and the catheterization head, so that the dilation tube and the dilation air bag can be kept in a vertical state when entering a prostate body channel, and the prostate body can be conveniently dilated; and then air is supplied into the inner cavity of the expansion air bag, so that the prostate body channel can be smoothly expanded, and the situation that the air bag in traditional equipment is folded and cannot smoothly enter the prostate channel is avoided.
Owner:DACHUAN DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL DAZHOU CITY

Precision Prostate Partial Resection Device

ActiveCN115040205BIncision instrumentsExcision instrumentsPartial resectionKnife blades
The present invention relates to a precise prostate partial resection device, comprising a tool holder and a plurality of cutting assemblies; the tool holder includes a main shaft, a first rotating seat and a second rotating seat which are axially spaced on the main shaft, the first rotating seat is located at the end of the main shaft, and the outer shape of the first rotating seat is smaller than that of the second rotating seat; the cutting assembly includes a support shaft connected between the first rotating seat and the second rotating seat, and a blade disposed on the support shaft, and one end of the support shaft connected to the second rotating seat deviates outward from the main shaft, so that an included angle is formed between the support shaft and the main shaft; each cutting assembly is arranged circumferentially between the first rotating seat and the second rotating seat, and when the tool holder rotates, it drives the cutting assembly to rotate. The conical small head of each cutting assembly close to the first rotating seat at the front end first removes the hyperplasia in the middle. During the advancing process, the cutting assembly works as a whole to cut the urethral orifice. The working process of the removal device is simple and fast, reducing the pain of the patient, with controllable cutting size and lower risk.
Owner:SHENZHEN UNIV +1

Ultrasound probe holder (precision prostate biopsy)

ActiveCN309669334SRadiologyAcoustics
1. The name of the design product: ultrasonic probe fixator (precise prostate puncture). 2. The use of the design product: used for the precise scale fixed support of ultrasonic probe. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1. 5. The rear view has been embodied in perspective view 2, and the rear view is omitted; the bottom view has been embodied in perspective view 3, and the bottom view is omitted.
Owner:孙在利

Prostate lifting device

The invention relates to a prostate lifting device, and belongs to the technical field of medical instruments. The prostate lifting device comprises a brake box and a conveying shaft rod, the brake box comprises a shell, a needle sliding block, a wire sliding block and an energy storage spring are arranged in the shell, and a needle excitation module is arranged outside the shell; the needle sliding block and the thread sliding block are in sliding connection with the shell, the sliding direction is parallel to the length direction of the conveying shaft rod, and the energy storage spring is used for storing energy for the needle sliding block. A puncture needle and a silk thread are arranged in the conveying shaft rod, the end of the puncture needle is in transmission connection with the needle sliding block, and the end of the silk thread is in transmission connection with the thread sliding block. The needle excitation module comprises an excitation block and an excitation interlock, the excitation interlock is matched with the excitation block, and the excitation block is used for releasing the elastic potential energy of the energy storage spring when the excitation interlock is started. By optimizing the internal structure and the excitation mechanism of the brake box, the whole structure is simple, the assembly is convenient, the requirements of clinical minimally invasive surgery are met, and the application prospect is good.
Owner:ZHEJIANG APELOA JIAYUAN BIOMEDICAL MATERIAL

Electric sighting target for perineal prostate precise puncture

The utility model discloses an electric aiming target for perineal prostate precise puncture, which comprises a target plate for positioning and guiding a puncture needle, and further comprises a card electric cylinder, a mounting seat is fixed on a lifting part of the card electric cylinder, a fixing part of the card electric cylinder is used for fixing an ultrasonic probe, the target plate is provided with a mounting lug, and the mounting seat is provided with a mounting groove. The installation protruding block is assembled in the installation groove in a sliding mode, the installation protruding block is provided with an elastic arm, the groove wall of the installation groove is provided with a first limiting part, the elastic arm is provided with a second limiting part, and the first limiting part and the second limiting part are mutually limited through the elastic force of the elastic arm, so that the target plate is fixed to the installation base in a replaceable mode. In this way, different target plates can be replaced quickly and conveniently, and the target plates can be driven by the card electric cylinder to perform quantitative inching in the vertical direction, so that adjustment of the target plates at different puncture heights is achieved.
Owner:WUHAN LEADWAY TECHNOLOGY CO LTD

Prostate glove, fingertip optical encoder, connector system, and related methods

ActiveUS12527517B2EndoscopesCatheterRectum wallMechanical engineering
Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a finger clip having a roller ring or wheel rotatably mounted thereto is disposed within an inflatable membrane. The roller ring can include a measurement pattern positioned opposite to optical fibers configured to receive light reflected from the measurement pattern. A user can put on the finger clip, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the inside of the membrane, which is pressed against the rectal wall, the roller ring can rotate with respect to the fibers such that the fibers move relative to the measurement pattern. A controller can sense light reflected through the fibers from the reference pattern and calculate or estimate various attributes of the prostate based on the reflected light.
Owner:MEDICAMETRIX

Optical excitation guided planning method and system based on photoacoustic imaging and storage medium

The present application relates to the technical field of medical imaging processing, in particular to a light excitation guide planning method and system based on photoacoustic imaging and a storage medium, comprising the following steps: planning a first path from an entrance end of a urethral region to a target end of a prostate region; acquiring photoacoustic signal data of a flexible optical fiber during the travel of the flexible optical fiber according to the first path in real time; determining position information of a front end of the flexible optical fiber in the photoacoustic signal data, and reconstructing a photoacoustic image in the photoacoustic signal data; registering the first path from the medical image to the photoacoustic image, and determining guide and correction information of the travel process in the registered photoacoustic image by using the first path and the position information of the front end of the flexible optical fiber. The present application pre-plans a guide path for introducing the flexible optical fiber into the prostate region through the urethra, and accurately positions the front end of the flexible optical fiber by using the guide path combined with ultrasonic guidance, so as to accurately guide the flexible optical fiber during the travel process.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Surgical system and its anchor delivery system, magazine and robotic arm

The present invention discloses a surgical system and its anchor delivery system, magazine, and robotic arm. Using rectal ultrasound to perform 3D scanning and imaging of the prostate, the surgeon can intuitively determine the release position and angle. The robotic arm adjusts its posture during surgery, while a servo motor automatically controls the release of the anchor. This system, after 3D ultrasound imaging and positioning of the prostate, automatically calculates the optimal position and angle based on an algorithm, making surgery more convenient and the release more precise.
Owner:HEFEI YILIANLITONG MEDICAL TECHNOLOGY CO LTD

Urethra-insertable ultrasound device for prostate treatment

A urethra-insertable ultrasound device for prostate treatment, which is configured to treat prostate by emitting ultrasound waves while inserted into the urethra, comprises: an ultrasound probe comprising one or more ultrasound transducers for emitting focused ultrasound waves; an imaging device installed on the ultrasound probe to obtain an image of the prostate; and a controller for controlling the operation of the ultrasound transducers by using the prostate image obtained by the imaging device. The controller controls the operation of the ultrasound transducers such that the focal positions of the focused ultrasound waves are not located outside a boundary of the prostate obtained from the prostate image.
Owner:KORUST

Implanted gel type auxiliary balloon catheter

The utility model relates to an implantation gel auxiliary balloon catheter which comprises a catheter body, the catheter body is a double-cavity tube, one of the double-cavity tube is a liquid injection hole, and the other one of the double-cavity tube is a gel injection hole. A forming cavity used for assisting gel filling is formed in the front end of the balloon, the balloon is arranged at the front end of the catheter, an outlet of the liquid injection hole is communicated with an inner cavity of the balloon, and an outlet of the gel injection hole is communicated with the forming cavity. A gel filling space is expanded between the prostate and the rectum by utilizing a balloon filling expansion principle, and the gel is fully and uniformly filled between the prostate and the rectum, so that the prostate and the rectum have enough isolation height and range after being filled with the gel, and a good and controllable isolation effect is achieved during radiotherapy.
Owner:JIANGSU CHANGMEI MEDICAL INSTR CO LTD