23 results about "Prostate gland" patented technology

This invention discloses a biomarker, reagent kit, and system for diagnosing bladder injury secondary to benign prostatic hyperplasia (BPH), relating to the field of biomedical detection technology. The biomarker for diagnosing bladder injury secondary to BPH is characterized in that it includes urinary DAB2 protein. This invention achieves (1) clinical applicability: accurate quantitative assessment of the degree of injury. The most significant clinical value of urinary DAB2 protein lies in its ability to transform traditional subjective bladder injury assessment into an objective quantitative indicator. (2) convenient detection: non-invasive and rapid assessment using urine samples. As a urine detection biomarker, urinary DAB2 protein completely changes the traditional bladder injury assessment's reliance on invasive or expensive examinations such as cystoscopy and CT. (3) clinical decision support: the grading diagnostic value of urinary DAB2 protein is directly translated into clinical decision support capabilities, helping to avoid the clinical dilemma of "overtreatment" or "undertreatment."

The present application relates to a kind of adjustable angle prostate puncture kit, including outer sheath and inner core, the inner core is arranged in outer sheath;The outer sheath is provided with passive bending part near puncture end;Inner core is provided with active bending part near puncture end;The other end of the inner core is provided with driving part, and the driving part is connected with active bending part;Driving part includes power supply and electrified guide wire, and one end of electrified guide wire is connection end, and one end is free end, connection end is connected with power supply, and free end is contacted with any metal coil on coil ring by rotating part control;The magnetic field attraction generated by the metal coil electrification is greater than the sum of the resistance of tissue and the resistance of material deformation.The circumferential angle of puncture sheath can be adjusted by the rotation control of conductive slip ring and knob, compared with the single direction adjustment structure, the direction selection range of puncture end can be expanded, which helps to avoid pubic obstruction and approach target area in different positions, so as to provide more path selection for lesion puncture sampling.

This invention discloses a prostate balloon dilation catheter, comprising a catheter body; a first balloon disposed outside the catheter body; and a blunt scoring body disposed along the axial direction of the first balloon on its surface, protruding from the surface of the first balloon, the blunt scoring body being used to press against a target location; wherein, in the uninflated state of the first balloon, the blunt scoring body is located at the fold position of the first balloon, the fold being a circumferential depression of the first balloon. This invention utilizes the blunt scoring body to press against the prostate tissue, creating stress concentration and thus assisting the anterior balloon in dilating the prostate at the target location. Compared to existing technologies, this effectively avoids the risk of scratches to the balloon and urethral wall.

This invention discloses a five-cavity urethral infusion catheter specifically designed for prostatectomy. The catheter includes a tube body with five independent cavities: a urination cavity for draining urine, distally connected to a drainage orifice; a urethral infusion cavity for infusing medication, distally connected to a urethral infusion orifice; a first balloon inflation cavity, distally connected to a first balloon for fixation in the bladder trigone; a second balloon inflation cavity, distally connected to a second balloon for urethral closure; and a third balloon inflation cavity, distally connected to a third balloon for compressing the prostatectomy wound. The third balloon, located between the first and second balloons, is apple / pear shaped and, when inflated, conforms to the prostatectomy wound. This invention, through its innovative three-balloon design and five-cavity structure, solves problems such as incomplete postoperative hemostasis and difficulty in medication infusion. The specially designed apple / pear shaped balloon can precisely compress the wound, and in conjunction with the medication infusion channels, significantly improves surgical outcomes.

A kind of auxiliary identification method for bladder neck disconnection of minimally invasive prostate cancer radical surgery, it is related to image recognition field, including obtaining video stream from endoscope, and carrying out pretreatment;Extract the multi-scale feature of real-time image in the video stream after pretreatment, generate multi-scale feature map;Position coding and deep feature extraction are carried out based on multi-scale feature map, obtain global feature map;Global feature map is mapped as the control point of Bezier curve, then a smooth cutting line is fitted;Global feature map and control point are processed, generate Gaussian heat map, output the probability distribution of the best cutting line and the farthest cutting line of bladder neck, and the segmentation result of prostate and bladder;It is used to solve the problems that traditional method is difficult to identify the best disconnection position of bladder neck, and cannot provide clear cutting line guidance.

The present invention relates to compositions comprising a pollen extract from Secale flowers (Secale cereale L, Rye Grass) and Teupolioside, preferably an extract of Ajuga Reptans titrated in Teupolioside. The present invention further relates to the use of such compositions for the prevention and / or treatment of benign prostatic hypertrophy (BPH).

The invention relates to a needle guide designed for use in transperineal prostate biopsy performed in urology and radiology, which enables the biopsy needle to be guided to the desired region of the prostate. The needle guide (1) according to the invention comprises, a body (2) attached to a probe and comprising a vertical body channel (3) perpendicular to the axis of the probe and movement direction of the needle (11), a disc (5) having an extension piece (6) on one surface extending into the body channel (3) or a groove (4), and on the other surface at least one disc channel (7) through which the needle (11) will be inserted, a disc cap (9) provided on the surface of the disc (5) having the cap protrusions (10), which closes over the disc channels (7) by opening and closing, disc cap projections (10) on the surface of the disc cap (9) facing the disc channels (7) and corresponding to the disc channels (7).

This invention relates to a urinary catheter for post-prostatectomy, comprising an outer sheath, a catheter disposed inside the outer sheath, and an expansion component disposed on the surface of the outer sheath. Compared with the prior art, this invention, through the protruding structure on the surface of the balloon, allows the doctor to achieve hemostasis on the wound after prostatectomy via the balloon. The protruding structure can closely fit the uneven interior of the wound after surgery, resulting in better hemostasis compared to the smooth balloon surface in the prior art. At the same time, since the interior of the protrusion is connected to the interior of the balloon, the expansion size of the protrusion during the balloon inflation phase can be affected by the unevenness of the wound surface, avoiding excessive pressure on the post-operative wound area. In addition, the design of multiple sub-protrusions can increase the contact area after the balloon is filled with water or air, resulting in better compression hemostasis.

The present invention relates to a biocompatible, tissue adhesive, chitosan flowable dressing, optionally modified with catechol, and suitable for treating bleeding in a physiological environment, e.g., gastrointestinal tract, bladder (in particular in connection with the TURP procedure). The characteristics and structures of the chitosan dressing are provided. Methods of making and using the chitosan dressing are also provided.

Devices, systems, and methods are claimed for the treatment of male urinary frequency disorders using volumetric tissue heating, e.g., via radiofrequency (RF) or ultrasound (US) energy applied to pelvic floor tissue or penile tissue. In one embodiment, a device for the non-invasive treatment of urinary frequency disorders is disclosed, the device being applicable externally to a perineal region of a male individual, the device comprising: at least one radiofrequency (RF) generator configured to generate RF energy; at least one RF electrode suitable for placement on a target perineal surface; and at least one control circuit connected to the RF generator, wherein the at least one control circuit is operable to cause the RF energy to selectively heat a portion of a urethra, a portion of one or more pelvic floor muscles, a portion of a prostate gland, or a portion of a urinary bladder.

To eliminate or reduce fiber burn-back, to facilitate cauterization and solidification, to obtain an excellent processing parameter, and to control formation and shapes of bubbles.SOLUTION: A laser device is configured to provide one or more laser pulses that are configured by a controller to have enough energy to form one or more steam bubbles in a liquid medium at a fiber distal delivery end. The one or more pulses are configured to perform the following with the controller: first, to form steam bubbles around a distal end of a distal end part of an endoscope and a distal delivery end of an optical fiber; second, to form second bubbles at a distal end of the first bubbles; and third, to expand the second bubbles so as to expand sufficient amount of a considerable part of the liquid medium from a space between the distal delivery end of the fiber and a target tissue when the first bubbles begin to collapse.SELECTED DRAWING: Figure 3B

A dilation device for an intra-body lumen, for example, a urethra partially occluded by an enlarged prostate in the form of a resilient curved body configured to be implanted in a cut around the lumen, and a method for dilating such a lumen by implanting a dilation device in a cut around the outside of the lumen. Also, a deployment system including a delivery device for the implant, and a device for dilating the lumen before and while the cut is being made, and a method of using the implant and the deployment system. The implant may be formed of a strip or a coiled wire. The cut may be performed in part by the implant. The cut may be performed by a sharp edge, and / or by application of electrical current to the area being cut, or by a piezoelectric transducer.

Relates to a muscle strengthening stimulation electrode device for the prostate and urinary incontinence that is used in contact with an electrode. By providing an electrode adapted to the shape of the human body, the treatment efficiency is high. In addition, it is equipped with a leg guide in the center of the front, and due to a more ergonomic shape design considering the curve of the user's legs, it minimizes discomfort, has no fatigue, and has the effect of inducing the legs to open at an appropriate angle.

The invention relates to medical technology and can be used in urology for drainage and treatment for the prophylaxis of postoperative complications in the prostate and urethra after surgical treatment of prostate adenoma.Summary of the invention consists in that the device comprises four symmetrical tubes (1, 2, 3, and 13) of different diameters and connected on a line along their longitudinal axis, one end (8) of the device is made blunt, the tubes at the opposite end (9) of the device are separate, each end of which is equipped with a branch pipe. In the tube (1) of a larger diameter are made three channels (4, 5, 6), where one channel (4) communicates with an elastic balloon (7) placed at the blunt end (8) of the device, and two channels (5, 6) pass through the balloon (7) and each ends with an opening (11) on the sides of the blunt end (8). The tube (2) is made of a smaller diameter than the tube (1) and ends with multiple holes (10) on the side of the blunt end (8) under the elastic balloon (7). The tube (3) is made with the smallest diameter and with the blind end under the elastic balloon (7), and along the path of tube (3) in its wall are made 4…5 holes (12) at a distance of 5…6 cm from each other. The tube (13) is made blind, the diameter of which is equal to the diameter of the tube (1), and in this tube (13) is placed an insulated coaxial cable (14) with one end reaching the balloon (7), where the corresponding end of the cable (14) is equipped with a coaxial dipole antenna (15), and the opposite end of the cable (14) is equipped with a connector (16) for connection to a microwave generator, in the tube (13) is also placed an optical fiber (17) with one end reaching the balloon (7), where the corresponding end of the optical fiber (17) is equipped with a transmitter with a diffuser emitter (18) for infrared waves, and the opposite end of the optical fiber (17) is equipped with a connector (19) for connection to an infrared wave generator. The device has a diameter of 28…30 Fr and is made of silicone or natural latex coated with polytetrafluoroethylene.

A surgical training model for simulating human prostate surgery may include a harvested porcine urethra. A harvested porcine vagina surrounds a portion of the harvested porcine urethra to define a simulated human prostate.

Disclosed is a “benign prostatic hyperplasia surgical device using an anchor assembly and a needle. The benign prostatic hyperplasia surgical device includes a plurality of anchors disposed on the prostate gland compressing the urethra and a ligature thread connecting the plurality of anchors to each other so that the plurality of anchors continuously compress prostatic tissues to allow the urethra to be open. Further, the benign prostatic hyperplasia surgical device of the present invention includes: an elastic needle receiving the plurality of anchors therein and inserted into the urethra to guide the plurality of anchors and the ligature thread so that the plurality of anchors and the ligature thread are located on the prostate gland; and a needle launching means for launching the needle so that the needle is inserted into the urethra to allow the plurality of anchors and the ligature thread to be discharged through the needle.

This invention relates to a prostate stapler device, comprising a drive handle and a gate housing. The drive handle has a mounting groove that mates with and fixes the gate housing. The gate housing contains a needle slider, a wire slider, and an energy-storing slider. The needle slider and the energy-storing slider pass through the bottom of the mounting groove and are connected to the drive handle. A limiting block is located at the endpoint of the needle slider's movement. A limiting hook is provided on the side of the limiting block facing the energy-storing slider. An energy-storing spring is provided on the energy-storing slider. A transmission block connected to the end of the energy-storing spring is located on the side wall of the needle slider. A blocking hook located at the bottom of the mounting groove and connected to the drive handle is provided on the side of the transmission block facing the energy-storing slider. This invention features pre-storing energy at the factory, eliminating the need for doctors to charge energy during surgery, reducing surgical steps, making surgery more labor-saving, convenient, and easy to operate. It also features self-locking of the energy-storing state to prevent accidental activation.

The application belongs to the technical field of medical devices, and particularly relates to a wearable tension display postoperative hemostasis device for prostate, which comprises a catheter and an auxiliary tube connected with the catheter; and further comprises a tensioning mechanism, wherein the tensioning mechanism comprises a connecting seat sleeved on a patient's leg, one side of the connecting seat is provided with a one-way ratchet tightener, the one-way ratchet tightener is internally provided with a tensioning rope, and one end of the tensioning rope is connected with a connecting ring on a first hook and a supporting plate. Compared with the traditional adhesive tape sticking method, the designed structure has multiple beneficial effects. Firstly, the operation is simple and convenient, and one person can complete the catheter pulling and fixing without the cooperation of two persons, thereby solving the problem of time and labor consumption in the traditional method. Secondly, the one-way ratchet tightener can provide continuous, stable and not easy to loosen pulling force, thereby ensuring that the water bag head of the catheter effectively compresses the prostate wound for a long time to stop bleeding, and avoiding the failure of hemostasis caused by insufficient adhesive force of the adhesive tape.

Provided herein are methods and compositions for reducing the expression and / or activity of an oncogenic transfer RNA (tRNA). Composition for treating cancer in the subject are disclosed, comprising an inhibitor of an oncogenic transfer RNA (tRNA) to a subject in need thereof, wherein the oncogenic tRNA comprises an inhibitory nucleic acid such as ARG-TCT-4-1, an siRNA, an shRNA, an miRNA, an antisense oligonucleotide, or a nucleic acid modification such as a locked nucleic acid, a phosphorothioate modification, a 2′—O-methyl modification, a 2′—O-methoxyethyl modification, a 2′-fluoro modification, a phosphorodiamidate modification, or a mesylphosphoramidate modification. The disclosed compositions are disclosed as treating cancers such as a sarcoma, a glioblastoma, an adrenocortical carcinoma, a cholangiocarcinonma, a melanoma, a glioma, a diffuse glioma, a mature B cell neoplasm, a non-small cell lung cancer, an esophagogastric adenocarcinoma, a pheochromocytoma, a hepatocellular carcinoma, an endometrial carcinoma, a pancreatic adenocarcinoma, a breast carcinoma, an invasive breast carcinoma, a head and neck squamous cell carcinoma, a bladder urothelial carcinoma, a colorectal adenocarcinoma, an ovarian epithelial tumor, a prostate adenocarcinoma, a cervical squamous cell carcinoma, a renal non-clear cell carcinoma, or a renal clear cell carcinoma.

The invention relates to medical technology and can be used in urology for drainage for the purposes of prophylaxis of postoperative complications in the prostate and urethra after surgical treatment of prostate adenoma.Summary of the invention consists in that the device comprises three symmetrical tubes (1, 2 and 3) of varying diameters and joined on a line along their longitudinal axis. One end (8) of the device is made blunt, the tubes at the opposite end (9) of the device are separate, each end of which is equipped with a connection, in the tube (1) of a larger diameter are made three channels (4, 5, 6), where one channel (4) communicates with an elastic balloon (7), placed at the blunt end (8) of the device, and two channels (5, 6) pass through the balloon (7) and each ends with an opening (11) on the sides of the blunt end (8). The tube (2) is made of a smaller diameter than the tube (1) and ends with multiple holes (10) on the side of the blunt end (8) under the elastic balloon (7). The tube (3) is made with the smallest diameter and is made with the blind end under the elastic balloon (7), and along the path of the tube (3) in its wall are made 4…5 holes (12) at a distance of 5…6 cm from each other, at the same time the device has a diameter of 28…30 Fr and is made of silicone or natural latex coated with polytetrafluoroethylene.

This invention discloses a prostate enucleator, comprising: an inner sheath, which is tubular; an outer sheath, which is tubular and coaxially sleeved on the inner sheath; a flexible segment comprising an inner flexible tube and an outer flexible tube coaxially arranged; one end of the inner flexible tube is fixedly connected to the inner sheath, and one end of the outer flexible tube is fixedly connected to the outer sheath; the other end of the flexible segment has an end plate; two traction wires are arranged at intervals, one end of which is fixedly connected to the end plate or the flexible segment, and the other end can be pulled to bend the flexible segment to one side, changing the angle of the end plate. The prostate enucleator provided by this invention can adjust the field of view of the enucleator without relying on the lever action of a rigid endoscope, reducing the force on the sphincter muscle.

A method for preventing and treating internal infections, e.g., urinary tract infections, caused by catheters is provided, in particular by reduction in catheter-associated biofilms. A coating composition is used to treat the catheter and applied through the catheter into the bladder or other body urinary tract organ to kill or neutralize microorganisms, including biofilms therein. The composition comprises a humectant and an antimicrobial with the antimicrobial including a monoquaternary ammonium compound or pharmaceutically acceptable salt thereof. The coating layer has antimicrobial cidal or static activity for at least about one hour.