The invention provides a manufacturing process of a spiral seam submerged arc welded pipe. The purpose of the present invention is achieved in this way: 1) raw material inspection, 2) stock preparation, 3) uncoiling, 4) leveling, 5) steel strip alignment, 6) disc shearing, 7) edge milling, 8) steel strip Delivery, 9) Steel strip edge pre-bending, 10) Forming, 11) Forming inspection, 12, 13) Internal and external automatic welding, 14, 15) Initial inspection, internal inspection, 16) Steel pipe cutting, 17) Manual repair welding, 18) X-ray inspection, 19) water pressure, 20) water pressure test inspection, 21) ultrasonic inspection, 22) magnetic particle inspection, 23) chamfering, 24) physical and chemical inspection of products, 25) finished product inspection, 26) spray marking. Submerged arc automatic welding can use large welding current, the arc heat is concentrated, the penetration depth is large, and the welding wire can be fed continuously, so its production efficiency is 5-10 times higher than that of manual arc welding; it saves materials and electric energy, and is environmentally friendly and harmless to the human body.