Continuous blood oxygen monitoring system in extracorporeal circulation and control method thereof

Abstract

The embodiment of the invention provides a continuous blood oxygen monitoring system in extracorporeal circulation and a control method thereof. The continuous blood oxygen monitoring system comprises a vein sensor, an artery sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a controller and a display, the vein sensor monitors the vein blood oxygen saturation degree; the artery sensor monitors arterial oxygen saturation and hematocrit; the blood flow sensor monitors the blood flow of the artery pipeline; the oxygen sensor monitors the oxygen concentration of the oxygenator; the carbon dioxide sensor monitors the carbon dioxide concentration of the oxygenator; the display provides an interaction control, responds to a trigger operation acting on the interaction control, sends an interaction instruction to the controller, and updates information displayed in an interaction interface according to the control of the controller; the controller receives the interaction instruction and executes processing corresponding to the interaction instruction; the processing includes controlling display information of the display; the display information comprises information corresponding to the monitoring parameters. The scheme ensures the safety and effectiveness of the treatment process.

Description

Technical Field

[0001] This invention relates to the field of blood oxygen monitoring technology, and in particular to a continuous blood oxygen monitoring system and its control method in extracorporeal circulation. Background Technology

[0002] Currently, the implementation of extracorporeal membrane oxygenation (ECMO) technology typically requires continuous monitoring of parameters such as blood oxygenation. Monitoring generally falls into two categories: manual blood sampling and analysis, and non-contact measurement. Manual blood sampling requires medical personnel to collect and test blood regularly and frequently, and the process is time-consuming, failing to reflect real-time blood parameters. Furthermore, existing monitoring devices mostly perform single-parameter detection; detecting more blood parameters requires additional equipment to be integrated into the ECMO system, increasing the complexity of system operation.

[0003] Overall, existing technologies suffer from operational complexity, low efficiency, and an inability to reflect real-time blood parameters. Summary of the Invention

[0004] The purpose of this invention is to provide a continuous blood oxygen monitoring system and its control method in extracorporeal circulation, so as to alleviate the problems of low operation complexity, low efficiency and inability to reflect real-time blood indicators in the prior art, thereby reducing operation complexity, improving efficiency and being able to reflect real-time blood indicators.

[0005] In a first aspect, embodiments of the present invention provide a continuous blood oxygen monitoring system for extracorporeal circulation. The system includes: a venous sensor, an arterial sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a spectrometer, a controller, and a display. The venous sensor and the arterial sensor are respectively disposed in the venous and arterial lines of an extracorporeal membrane oxygenation (ECMO) device. The oxygen sensor and the carbon dioxide sensor are both connected to the gas lines of the ECMO device. The arterial sensor and the venous sensor are both connected to the spectrometer. The spectrometer and the display are both connected to the controller. The venous sensor is used to monitor the blood oxygen saturation signal in the venous line; the arterial sensor is used to monitor the blood oxygen saturation signal and hematocrit in the arterial line; the blood flow sensor is used to monitor the blood flow rate in the ECMO device lines; and the oxygen sensor is used to monitor the blood entering the extracorporeal membrane oxygenation (ECMO) device. The oxygen concentration of the gas in the oxygenator; the carbon dioxide sensor for monitoring the carbon dioxide concentration of the gas output from the oxygenator; the spectrometer for converting the venous oxygen saturation signal and the arterial oxygen saturation signal into digital signals corresponding to venous oxygen saturation and arterial oxygen saturation, respectively; the interactive interface of the display for providing interactive controls, responding to trigger operations applied to the interactive controls, sending interactive instructions of the interactive controls to the controller, and updating the information displayed on the interactive interface according to the control of the controller; the controller for receiving the interactive instructions and executing the processing of the interactive instructions; the processing includes controlling the display information of the display; the display information includes at least some monitoring parameters; the monitoring parameters include: the venous oxygen saturation, the arterial oxygen saturation, the hematocrit, the blood flow, the oxygen concentration, and the carbon dioxide concentration.

[0006] In a preferred embodiment of the present invention, the above-mentioned display information further includes: the patient's patient information; the patient information includes: the patient's body surface area.

[0007] In a preferred embodiment of the present invention, the interactive interface is further configured to provide a detail information query control for displaying patient details, respond to a trigger operation applied to the detail information query control, send an interactive instruction of the detail information query control to the controller, and display the patient details of the patient according to the control of the controller; the patient details include: the patient's ID, height, and weight.

[0008] In a preferred embodiment of the present invention, the display is a touch device and the interactive control is a virtual control in the interactive interface; or, the display is a non-touch device and the interactive control is a physical button on the display.

[0009] In a preferred embodiment of the present invention, the interactive control further includes a plurality of curve selection controls, each of which corresponds to a different monitoring parameter; the interactive instruction is a first target instruction corresponding to the first target curve selection control; the first target curve selection control is one of the plurality of curve selection controls; the controller is used to receive the first target instruction and control the main interface of the interactive interface in the display to display the information of the monitoring parameter corresponding to the target curve selection control.

[0010] In a preferred embodiment of the present invention, the monitoring parameters further include: the hemoglobin concentration, the cardiac index, the oxygen consumption index, the oxygen supply index, the oxygen uptake rate, the membrane lung carbon dioxide excretion index, and the oxygen supply index and membrane lung carbon dioxide removal ratio. The controller is further configured to calculate the hemoglobin concentration based on the hematocrit; calculate the cardiac index based on the blood flow rate; calculate the oxygen consumption index based on the hemoglobin concentration, the cardiac index, the arterial oxygen saturation, and the venous oxygen saturation; calculate the oxygen supply index based on the hemoglobin concentration, the arterial oxygen saturation, and the cardiac index; calculate the oxygen uptake rate based on the arterial oxygen saturation and the venous oxygen saturation; calculate the membrane lung carbon dioxide excretion index based on the gas flow rate and the carbon dioxide concentration; and calculate the oxygen supply index and membrane lung carbon dioxide removal ratio based on the membrane lung carbon dioxide excretion index and the oxygen supply index.

[0011] In a preferred embodiment of the present invention, the monitoring parameters are arranged vertically in the preset vertical coordinate of the interactive interface; the horizontal coordinate corresponding to the vertical coordinate is the time coordinate; the time coordinates corresponding to the monitoring parameters are the same.

[0012] In a preferred embodiment of the present invention, the display is further configured to respond to a viewing operation of the target monitoring parameters at the current moment in the interactive interface, and to display the target monitoring parameters corresponding to the first parameter change information within a first set time period prior to the current moment.

[0013] In a preferred embodiment of the present invention, the system further includes a memory connected to the controller; the vein sensor and the arterial sensor acquire the venous blood oxygen saturation signal and the arterial blood oxygen saturation signal respectively through the vein sensor probe and the arterial sensor probe; the memory is used to store historical calibration data of the vein sensor probe and the arterial sensor probe.

[0014] In a preferred embodiment of the present invention, the display is further configured to, in response to a screenshot operation on the interactive interface at the current moment, capture information on the change of the second parameter of the monitoring parameter within a second set time period before and after the current moment; the memory is further configured to store the information on the change of the second parameter.

[0015] In a preferred embodiment of the present invention, the display is further configured to control the interactive interface to magnify the display information of the specified area in response to a magnification command for the specified area of ​​the interactive interface.

[0016] Secondly, embodiments of the present invention also provide a control method for a continuous blood oxygen monitoring system in extracorporeal circulation, applied to the aforementioned continuous blood oxygen monitoring system in extracorporeal circulation; the method includes: monitoring the blood oxygen saturation signal of blood in the venous tubing using a venous sensor; monitoring the blood oxygen saturation signal and hematocrit of blood in the arterial tubing using an arterial sensor; monitoring the blood flow rate in the tubing of the extracorporeal membrane oxygenation (ECMO) device using a blood flow sensor; monitoring the oxygen concentration of gas entering the oxygenator using an oxygen sensor; monitoring the carbon dioxide concentration of gas output from the oxygenator using a carbon dioxide sensor; and separating the venous blood oxygen saturation signal and the arterial blood oxygen saturation signal using a spectrometer. The oxygen saturation is converted into digital signals corresponding to venous oxygen saturation and arterial oxygen saturation. An interactive control is provided via a display. In response to a trigger operation applied to the interactive control, an interactive instruction corresponding to the interactive control is sent to the controller, and the information displayed in the interactive interface is updated according to the control of the controller. The controller receives the interactive instruction and executes the processing corresponding to the interactive instruction. The processing includes controlling the display information. The displayed information includes information corresponding to at least some of the monitored parameters. The monitored parameters include: venous oxygen saturation, arterial oxygen saturation, hematocrit, blood flow, oxygen concentration, and carbon dioxide concentration.

[0017] The embodiments of the present invention have the following beneficial technical effects: This invention provides a continuous blood oxygen monitoring system and control method for extracorporeal circulation. The system includes: a venous sensor, an arterial sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a spectrometer, a controller, and a display. The venous sensor and the arterial sensor are respectively installed in the venous and arterial lines of an extracorporeal membrane oxygenation (ECMO) device. The oxygen sensor and the carbon dioxide sensor are both connected to the oxygenator of the ECMO device. The arterial sensor and the venous sensor are both connected to the spectrometer. The spectrometer and the display are both connected to the controller. The venous sensor is used to monitor the venous blood oxygen saturation signal of the venous line. The arterial sensor is used to monitor the arterial blood oxygen saturation signal and hematocrit of the arterial line. The blood flow sensor is used to monitor the blood flow of the arterial line. The oxygen sensor is used to monitor the blood flow of the arterial line. The system integrates multiple sensors and a spectrometer to monitor the oxygen concentration in the oxygenator; a carbon dioxide sensor monitors the carbon dioxide concentration in the oxygenator; a spectrometer converts the venous oxygen saturation signal and the arterial oxygen saturation signal into venous oxygen saturation and arterial oxygen saturation, respectively; an interactive interface provides interactive controls, responds to trigger operations on the interactive controls, sends interactive instructions to the controller, and updates the information displayed on the interactive interface according to the controller's control; the controller receives the interactive instructions and processes them; the processing includes controlling the display information; the displayed information includes at least some monitoring parameters; the monitoring parameters include: venous oxygen saturation, arterial oxygen saturation, hematocrit, blood flow, oxygen concentration, and carbon dioxide concentration. This continuous oxygenation monitoring system for extracorporeal circulation integrates multiple sensors and a spectrometer to monitor and analyze key blood parameters in real time, and uses an interactive interface to achieve dynamic data display and patient control. It enables continuous monitoring of multiple parameters, significantly improving monitoring accuracy and ease of operation, and ensuring the safety and effectiveness of the treatment process.

[0018] Meanwhile, this continuous blood oxygenation monitoring system in extracorporeal circulation can achieve consumable-free monitoring by combining it with arteriovenous probe components, and does not come into direct contact with blood during the monitoring process. Attached Figure Description

[0019] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0020] Figure 1This is a schematic diagram of a continuous blood oxygen monitoring system in extracorporeal circulation provided by an embodiment of the present invention; Figure 2 A schematic diagram of an interactive interface provided in an embodiment of the present invention; Figure 3 A schematic diagram of a second interactive interface provided in an embodiment of the present invention; Figure 4 A schematic diagram of a third interactive interface provided in an embodiment of the present invention; Figure 5 A schematic diagram of a fourth interactive interface provided in an embodiment of the present invention; Figure 6 A schematic diagram of the fifth interactive interface provided in an embodiment of the present invention; Figure 7 This is a flowchart illustrating a control method for a continuous blood oxygen monitoring system in extracorporeal circulation, as provided in an embodiment of the present invention.

[0021] Icons: 11-Vein sensor; 12-Artery sensor; 13-Blood flow sensor; 14-Oxygen sensor; 15-Carbon dioxide sensor; 16-Spectrometer; 17-Controller; 18-Display; 19-Interface; 21-Vein line; 22-Artery line; 23-Oxygenator; 40-Power adapter; 41-Battery; 42-Air-oxygen mixer; 43-Oxygen source; 44-Air source. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. The components of the embodiments of the present invention described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0023] During extracorporeal membrane oxygenation (ECMO), continuous monitoring of parameters such as blood oxygenation is typically required. Monitoring generally falls into two categories: manual blood sampling and analysis, and non-contact measurement. Manual blood sampling requires medical personnel to collect and test blood regularly and frequently, and the process is time-consuming, failing to reflect real-time blood parameters. Furthermore, existing monitoring devices mostly perform single-parameter detection; detecting more blood parameters requires additional equipment to be integrated into the ECMO system, increasing operational complexity. Overall, current technologies suffer from operational complexity, low efficiency, and the inability to reflect real-time blood parameters.

[0024] Based on this, embodiments of the present invention provide a continuous blood oxygen monitoring system and its control method for extracorporeal circulation. This technology integrates multiple sensors and a spectrometer to monitor and analyze key blood parameters in real time, and utilizes an interactive interface to achieve dynamic data display and patient control, significantly improving monitoring accuracy and ease of operation, and ensuring the safety and effectiveness of the treatment process. For ease of understanding, a continuous blood oxygen monitoring system for extracorporeal circulation is first introduced.

[0025] Example 1 In an embodiment of the present invention, Figure 1 This is a schematic diagram of a continuous blood oxygen monitoring system in extracorporeal circulation provided in an embodiment of the present invention.

[0026] Depend on Figure 1As seen, the continuous oxygenation monitoring system for extracorporeal circulation includes: a venous sensor 11, an arterial sensor 12, a blood flow sensor 13, an oxygen sensor 14, a carbon dioxide sensor 15, a spectrometer 16, a controller 17, and a display 18. The venous sensor 11 and the arterial sensor 12 are respectively installed in the venous line 21 and the arterial line of the extracorporeal membrane oxygenation (ECMO) device. The oxygen sensor 14 and the carbon dioxide sensor 15 are both connected to the gas line of the ECMO device, specifically, to the gas line connecting to the oxygenator 23. The arterial sensor 12 and the venous sensor 11 are both connected to the spectrometer 16. The spectrometer 16 and the display 18 are both connected to the controller 17. The venous sensor 11 is used to monitor the blood oxygen saturation signal in the venous line 21. The arterial sensor 12 is used to monitor the blood oxygen saturation signal and hematocrit in the arterial line 22. The blood flow sensor 13 is used to monitor the blood flow rate in the lines of the ECMO device, specifically, in the arterial line 22. The blood flow rate can be the blood flow rate of the aforementioned venous line 21; the aforementioned oxygen sensor 14 is used to monitor the oxygen concentration of the gas entering the aforementioned oxygenator 23; the aforementioned carbon dioxide sensor 15 is used to monitor the carbon dioxide concentration of the gas output from the aforementioned oxygenator 23; the aforementioned spectrometer 16 is used to convert the aforementioned venous blood oxygen saturation signal and the aforementioned arterial blood oxygen saturation signal into digital signals corresponding to venous blood oxygen saturation and arterial blood oxygen saturation, respectively; the aforementioned display 18's interactive interface is used to provide interactive controls, respond to trigger operations acting on the aforementioned interactive controls, send interactive instructions of the aforementioned interactive controls to the aforementioned controller 17, and update the information displayed on the aforementioned interactive interface according to the control of the aforementioned controller 17; the aforementioned controller 17 is used to receive the aforementioned interactive instructions and execute the processing of the aforementioned interactive instructions; the aforementioned processing includes controlling the display information of the aforementioned display 18; the aforementioned display information includes at least some monitoring parameters; the aforementioned monitoring parameters include: the aforementioned venous blood oxygen saturation, the aforementioned arterial blood oxygen saturation, the aforementioned hematocrit, the aforementioned blood flow rate, the aforementioned oxygen concentration, and the aforementioned carbon dioxide concentration.

[0027] The aforementioned venous sensor 11 and arterial sensor 12 are both connected to the aforementioned spectrometer 16 via interface 19; the aforementioned blood flow sensor 13, oxygen sensor 14, and carbon dioxide sensor 15 are respectively connected to the aforementioned controller 17 via interface 19; the aforementioned controller 17 is connected to battery 41; the aforementioned system is also connected to the power adapter 40 of the external device; the aforementioned extracorporeal membrane oxygenation device also includes an air-oxygen mixer 42, an oxygen source 43, and an air source 44; the aforementioned oxygen source 43 and air source 44 are both connected to the air-oxygen mixer 42.

[0028] Furthermore, the displayed information also includes: the patient's patient information; the patient information includes: the patient's body surface area.

[0029] Furthermore, the aforementioned interactive interface is also used to provide a detailed information query control for displaying patient details, respond to a trigger operation applied to the detailed information query control, send an interactive instruction for the detailed information query control to the controller, and display the patient details according to the control of the controller 17; the patient details include: the patient's ID, height, and weight.

[0030] For ease of understanding, Figure 2 A schematic diagram of an interactive interface provided in an embodiment of the present invention; Figure 3 This is a schematic diagram of a second interactive interface provided in an embodiment of the present invention.

[0031] Among them, there are Figure 2 As seen in option 3, the aforementioned display 18 is a touch device, and the aforementioned interactive controls are virtual controls in the aforementioned interactive interface; or, the aforementioned display is a non-touch device, and the aforementioned interactive controls are physical buttons on the aforementioned display 18.

[0032] Depend on Figure 3 As can be seen, the above patient information first displays BSA body surface area information on the interface ( Figure 3 The patient details will be displayed in the upper left corner. Medical staff can click once or multiple times, or long-press, to see further details about the patient. Figure 3 (Information in the pop-up sub-display box).

[0033] By directly displaying BSA information, medical staff can more easily make a preliminary confirmation of whether the patient information entered in the device matches the actual patient. The patient details displayed after clicking once help medical staff to quickly conduct a secondary review.

[0034] In practical applications, displaying the above patient information facilitates information review by medical staff.

[0035] Furthermore, the interactive control includes multiple curve selection controls, each of which corresponds to different monitoring parameters; the interactive instruction is a first target instruction corresponding to the first target curve selection control; the first target curve selection control is one of the multiple curve selection controls; the controller 17 is used to receive the first target instruction and control the main interface of the interactive interface in the display 18 to display the information of the monitoring parameters corresponding to the target curve selection control.

[0036] Depend on Figure 4As can be seen, in actual operation, medical staff can choose any of the monitoring parameters corresponding to the above target curve selection control according to their needs, thus achieving a higher degree of autonomy.

[0037] Furthermore, the aforementioned monitoring parameters also include: the hemoglobin concentration, the cardiac index, the oxygen consumption index, the oxygen supply index, the oxygen uptake rate, the membrane lung carbon dioxide excretion index, and the oxygen supply index and membrane lung carbon dioxide removal ratio. The controller 17 is also used to calculate the hemoglobin concentration based on the hematocrit; calculate the cardiac index based on the blood flow rate; calculate the oxygen consumption index based on the hemoglobin concentration, the cardiac index, the arterial oxygen saturation, and the venous oxygen saturation; calculate the oxygen supply index based on the hemoglobin concentration, the arterial oxygen saturation, and the cardiac index; calculate the oxygen uptake rate based on the arterial oxygen saturation and the venous oxygen saturation; calculate the membrane lung carbon dioxide excretion index based on the gas flow rate and the carbon dioxide concentration; and calculate the oxygen supply index and membrane lung carbon dioxide removal ratio based on the membrane lung carbon dioxide excretion index and the oxygen supply index.

[0038] The formula for calculating hemoglobin concentration based on the hematocrit is as follows: HB=HCT / 3 HCT stands for hematocrit.

[0039] Furthermore, based on the above blood flow calculation, the formula for calculating the cardiac index is as follows: CI=(a_QBlood) / BSA Where CI is the cardiac index, BSA is the body surface area, and a_QBlood is the blood flow.

[0040] Furthermore, based on the aforementioned hemoglobin concentration, arterial oxygen saturation, and venous oxygen saturation, the formula for calculating the oxygen consumption index is as follows: VO2i=((0.0138×Hb×SaO2)–(0.0138×Hb×SvO2))×CI×10 Wherein, VO2i is the oxygen consumption index, SvO2 is the venous blood oxygen saturation, and SaO2 is the arterial blood oxygen saturation.

[0041] Furthermore, based on the aforementioned hemoglobin concentration, arterial oxygen saturation, and cardiac index, the formula for calculating the oxygen supply index is as follows: DO2i=(0.0138×Hb×SaO2)×CI×10 Wherein, DO2i is the oxygen supply index.

[0042] Furthermore, based on the aforementioned arterial and venous oxygen saturation, the formula for calculating the oxygen uptake rate is as follows: O2ER=(SaO2-SvO2) / SaO2×100(%) O2ER is the oxygen uptake rate.

[0043] Furthermore, based on the aforementioned gas flow rate and carbon dioxide concentration, the formula for calculating the membrane lung carbon dioxide excretion index is as follows: VCO2i = GF × CO2 × 100 (%) Wherein, VCO2i is the carbon dioxide excretion index of the membrane lung, GF is the gas flow rate (the gas flow rate can be input from the value fed back by the extracorporeal membrane oxygenation device, or it can be detected by the flow sensor. Specifically, the gas flow rate refers to the flow rate of gas entering the oxygenator. In one embodiment, the oxygen sensor integrates a gas flow rate detection function, and the gas flow rate GF entering the oxygenator can be obtained by the oxygen sensor), and CO2 is the carbon dioxide concentration.

[0044] Furthermore, based on the aforementioned membrane lung carbon dioxide excretion index and oxygen supply index, the calculation formula for the oxygen supply index and membrane lung carbon dioxide removal ratio is: DO2i / VCO2i.

[0045] The monitoring parameters are arranged vertically on the preset vertical axis of the interactive interface; the horizontal axis corresponding to the vertical axis is the time axis; the monitoring parameters have the same time axis.

[0046] For ease of understanding, Figure 5 This is a schematic diagram of a fourth interactive interface provided in an embodiment of the present invention.

[0047] Depend on Figure 5 As can be seen, based on the correlation between the monitoring parameters, the monitoring parameters are vertically arranged in the preset vertical axis of the interactive interface, so that the monitoring parameters corresponding to the same time can be seen. For example, venous blood oxygen saturation, arterial blood oxygen saturation, and oxygen uptake rate are vertically arranged in the first preset vertical axis of the interactive interface.

[0048] Furthermore, the aforementioned display 18 is also used to display, in response to a viewing operation of the target monitoring parameters at the current moment in the aforementioned interactive interface, the first parameter change information of the target monitoring parameters within a first set time period prior to the current moment.

[0049] For ease of understanding, Figure 6 This is a schematic diagram of the fifth interactive interface provided in an embodiment of the present invention.

[0050] Depend on Figure 6As can be seen, medical staff can perform the above-mentioned viewing operation on the target monitoring parameters at the current moment in the above-mentioned interactive interface, so as to display the first parameter change information of the target monitoring parameters within the first set time period before the current moment, and magnify the first parameter change information.

[0051] In some examples, the system further includes a memory connected to the controller 17; the vein sensor and the arterial sensor acquire the venous blood oxygen saturation signal and the arterial blood oxygen saturation signal respectively through the vein sensor probe and the arterial sensor probe; the memory is used to store historical calibration data of the vein sensor probe and the arterial sensor probe.

[0052] For ease of understanding, Figure 7 This is a schematic diagram of the sixth interactive interface provided in an embodiment of the present invention.

[0053] Furthermore, the display 18 is also used to capture the second parameter change information of the monitoring parameter within a second set time period before and after the current time in response to a screenshot operation on the interactive interface at the current moment; the memory is also used to store the second parameter change information.

[0054] Furthermore, the aforementioned display 18 is also used to control the aforementioned interactive interface to magnify the aforementioned display information of the specified area in response to a magnification command for the specified area of ​​the aforementioned interactive interface.

[0055] In actual operation, the above-mentioned interactive controls include a screen lock control, and the above-mentioned interactive instructions are screen lock instructions; the above-mentioned controller is used to control the above-mentioned display to enter the screen lock state according to the above-mentioned screen lock instructions, and the above-mentioned display in the screen lock state will lock the above-mentioned interactive interface.

[0056] Furthermore, the aforementioned interactive control includes an alarm control, the aforementioned interactive instruction is an alarm instruction, and the aforementioned controller is used to control the alarm device of the aforementioned system to issue a warning signal according to the aforementioned alarm instruction, and to control the aforementioned display 18 to display alarm information.

[0057] This invention provides a continuous blood oxygen monitoring system and control method for extracorporeal circulation. The system includes: a venous sensor, an arterial sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a spectrometer, a controller, and a display for presenting an interactive interface. The venous sensor and the arterial sensor are respectively installed in the venous and arterial lines of an external extracorporeal membrane oxygenation (ECMO) device. The inlet and outlet lines of the oxygenator of the ECMO device are respectively connected to the oxygen sensor and the carbon dioxide sensor. The arterial sensor and the venous sensor are respectively connected to the spectrometer. The spectrometer and the display are respectively connected to the controller. The venous sensor is used to monitor the venous blood oxygen saturation signal of the venous line. The arterial sensor is used to monitor the arterial blood oxygen saturation signal and hematocrit of the arterial line. The blood flow sensor is used to monitor the blood flow of the arterial or venous line. The sensor monitors the oxygen concentration of the gas entering the oxygenator; the carbon dioxide sensor monitors the carbon dioxide concentration of the gas output from the oxygenator; the spectrometer converts the venous oxygen saturation signal and the arterial oxygen saturation signal into digital signals corresponding to venous and arterial oxygen saturation, respectively; the display provides interactive controls, responding to trigger operations on the interactive controls by sending interactive instructions corresponding to the interactive controls to the controller, and updating the information displayed in the interactive interface according to the control of the controller; the controller receives the interactive instructions and executes the processing corresponding to the interactive instructions; the processing includes controlling the display information; the displayed information includes information corresponding to at least some of the monitored parameters; the monitored parameters include: venous oxygen saturation, arterial oxygen saturation, hematocrit, blood flow, oxygen concentration, and carbon dioxide concentration. This continuous oxygenation monitoring system in extracorporeal circulation, by integrating multiple sensors and a spectrometer, monitors and analyzes key blood parameters in real time, and achieves dynamic data display and patient control through an interactive interface, significantly improving monitoring accuracy and ease of operation, and ensuring the safety and effectiveness of the treatment process.

[0058] Example 2 Based on the above embodiments, Figure 7 This is a flowchart illustrating a control method for a continuous blood oxygen monitoring system in extracorporeal circulation, as provided in an embodiment of the present invention.

[0059] Depend on Figure 7 As seen, the method includes: Step S101: Monitor the blood oxygen saturation signal of the blood in the venous tubing using a venous sensor; monitor the blood oxygen saturation signal and hematocrit of the blood in the arterial tubing using an arterial sensor; monitor the blood flow of the arterial or venous tubing using a blood flow sensor; monitor the oxygen concentration of the gas entering the oxygenator using an oxygen sensor; and monitor the carbon dioxide concentration of the gas output from the oxygenator using a carbon dioxide sensor.

[0060] Step S102: The above-mentioned venous blood oxygen saturation signal and the above-mentioned arterial blood oxygen saturation signal are converted into digital signals corresponding to venous blood oxygen saturation and arterial blood oxygen saturation respectively by a spectrometer.

[0061] Step S103: Provide interactive controls through the display, and in response to the trigger operation applied to the interactive controls, send the interactive instructions corresponding to the interactive controls to the controller, and update the information displayed in the interactive interface according to the control of the controller.

[0062] Step S104: Receive the interaction instruction through the controller and execute the processing corresponding to the interaction instruction; the processing includes controlling the display information of the display; the display information includes information corresponding to at least some monitoring parameters; the monitoring parameters include: venous blood oxygen saturation, arterial blood oxygen saturation, hematocrit, blood flow, oxygen concentration and carbon dioxide concentration.

[0063] In actual operation, after step S108, the method further includes: calculating the hemoglobin concentration based on the hematocrit using the controller; calculating the cardiac index based on the blood flow rate; calculating the oxygen consumption index based on the hemoglobin concentration, arterial oxygen saturation, and venous oxygen saturation; calculating the oxygen supply index based on the hemoglobin concentration, arterial oxygen saturation, and cardiac index; calculating the oxygen uptake rate based on the arterial oxygen saturation and venous oxygen saturation; calculating the membrane lung carbon dioxide removal index based on the gas flow rate and carbon dioxide concentration; and calculating the oxygen supply index and membrane lung carbon dioxide removal ratio based on the membrane lung carbon dioxide removal index and the oxygen supply index. The monitoring parameters also include: the hemoglobin concentration, cardiac index, oxygen consumption index, oxygen supply index, oxygen uptake rate, membrane lung carbon dioxide removal index, oxygen supply index, and membrane lung carbon dioxide removal ratio.

[0064] Furthermore, the above method also includes: displaying, in response to a viewing operation of the target monitoring parameters at the current moment in the above interactive interface, information on the change of the first parameter of the target monitoring parameters within a first set time period prior to the current moment.

[0065] The system further includes a memory connected to the controller; the vein sensor and the arterial sensor acquire the venous blood oxygen saturation signal and the arterial blood oxygen saturation signal respectively through the vein sensor probe and the arterial sensor probe; the method further includes storing historical calibration data of the vein sensor probe and the arterial sensor probe in the memory.

[0066] Furthermore, the above method also includes: in response to a screenshot operation on the interactive interface at the current moment, capturing the second parameter change information of the monitoring parameter within a second set time period before and after the current moment; and storing the second parameter change information in the memory.

[0067] Furthermore, the above method also includes: controlling the interactive interface to magnify the display information of the specified area in response to a magnification command for the specified area of ​​the interactive interface.

[0068] The present invention provides a control method for a continuous blood oxygen monitoring system in extracorporeal circulation. Its implementation principle and the resulting technical effects are the same as those of the aforementioned continuous blood oxygen monitoring system in extracorporeal circulation. For the sake of brevity, any parts not mentioned in the embodiments of the control method for the continuous blood oxygen monitoring system in extracorporeal circulation can be referred to the corresponding content in the aforementioned embodiments of the continuous blood oxygen monitoring system in extracorporeal circulation.

[0069] Therefore, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the invention without inventive effort are within the scope of protection of the invention.

[0070] Furthermore, in the description of the embodiments of the present invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in the present invention based on the specific circumstances.

[0071] In the description of this invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. Finally, it should be noted that the above embodiments are merely specific implementations of the present invention, used to illustrate the technical solutions of the present invention, and not to limit them. The scope of protection of the present invention is not limited thereto. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that any person skilled in the art can still modify or easily conceive of changes to the technical solutions described in the foregoing embodiments within the scope of the technology disclosed in the present invention, or make equivalent substitutions for some of the technical features; and these modifications, changes, or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention, and should all be covered within the scope of protection of the present invention.

Claims

1. A continuous blood oxygen monitoring system for extracorporeal circulation, characterized in that, The system includes: a vein sensor, an artery sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a spectrometer, a controller, and a display; the vein sensor and the artery sensor are respectively installed in the vein and artery lines of the extracorporeal membrane oxygenation (ECMO) device; the oxygen sensor and the carbon dioxide sensor are both connected to the gas lines of the ECMO device; the artery sensor and the vein sensor are both connected to the spectrometer; the spectrometer and the display are both connected to the controller; The vein sensor is used to monitor the blood oxygen saturation signal of the blood in the vein. The arterial sensor is used to monitor the blood oxygen saturation signal and hematocrit of the blood in the arterial tubing; The blood flow sensor is used to monitor the blood flow in the tubing of the extracorporeal membrane oxygenation (ECMO) device. The oxygen sensor is used to monitor the oxygen concentration of the gas entering the oxygenator; The carbon dioxide sensor is used to monitor the carbon dioxide concentration of the gas output from the oxygenator; The spectrometer is used to convert the venous blood oxygen saturation signal and the arterial blood oxygen saturation signal into digital signals corresponding to venous blood oxygen saturation and arterial blood oxygen saturation, respectively. The interactive interface of the display is used to provide interactive controls, respond to trigger operations applied to the interactive controls, send interactive instructions of the interactive controls to the controller, and update the information displayed on the interactive interface according to the control of the controller. The controller is used to receive the interactive instruction and execute the processing of the interactive instruction; the processing includes controlling the display information of the display; the display information includes at least some monitoring parameters; the monitoring parameters include: venous blood oxygen saturation, arterial blood oxygen saturation, hematocrit, blood flow, oxygen concentration, and carbon dioxide concentration.

2. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 1, characterized in that, The displayed information also includes: the patient's patient information; the patient information includes: the patient's body surface area.

3. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 2, characterized in that, The interactive interface is also used to provide a detailed information query control for displaying patient details, respond to a trigger operation applied to the detailed information query control, send an interactive instruction of the detailed information query control to the controller, and display the patient details according to the control of the controller; The patient details include: the patient's ID, height, and weight.

4. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 1, characterized in that, The display is a touch device, and the interactive control is a virtual control in the interactive interface; or, the display is a non-touch device, and the interactive control is a physical button on the display.

5. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 1, characterized in that, The interactive control also includes multiple curve selection controls, each of which corresponds to a different monitoring parameter; the interactive instruction is a first target instruction corresponding to the first target curve selection control; the first target curve selection control is one of the multiple curve selection controls. The controller is used to receive the first target instruction and control the main interface of the interactive interface in the display to display the monitoring parameter information corresponding to the target curve selection control.

6. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 1, characterized in that, The monitoring parameters also include: the hemoglobin concentration, the cardiac index, the oxygen consumption index, the oxygen supply index, the oxygen uptake rate, the membrane lung carbon dioxide excretion index, and the oxygen supply index and membrane lung carbon dioxide removal ratio; The controller is further configured to calculate hemoglobin concentration based on the hematocrit; calculate cardiac index based on blood flow; calculate oxygen consumption index based on hemoglobin concentration, cardiac index, arterial oxygen saturation, and venous oxygen saturation; calculate oxygen supply index based on hemoglobin concentration, arterial oxygen saturation, and cardiac index; calculate oxygen uptake rate based on arterial oxygen saturation and venous oxygen saturation; calculate membrane lung carbon dioxide removal index based on gas flow and carbon dioxide concentration; and calculate oxygen supply index and membrane lung carbon dioxide removal ratio based on membrane lung carbon dioxide removal index and oxygen supply index.

7. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 6, characterized in that, The monitoring parameters are arranged vertically in the preset vertical coordinate of the interactive interface; the horizontal coordinate corresponding to the vertical coordinate is the time coordinate; the monitoring parameters have the same time coordinate.

8. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 1, characterized in that, The display is also used to respond to a viewing operation of the target monitoring parameters at the current moment in the interactive interface, and to display the target monitoring parameters corresponding to the first parameter change information within a first set time period before the current moment.

9. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 8, characterized in that, The system also includes a memory connected to the controller; the vein sensor and the arterial sensor acquire the venous blood oxygen saturation signal and the arterial blood oxygen saturation signal respectively through the vein sensor probe and the arterial sensor probe; the memory is used to store the historical calibration data of the vein sensor probe and the arterial sensor probe.

10. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 9, characterized in that, The display is also configured to respond to a screenshot operation on the interactive interface at the current moment, and capture the second parameter change information of the monitoring parameter within a second set time period before and after the current moment; The memory is also used to store information about changes in the second parameter.

11. The continuous blood oxygen monitoring system during extracorporeal circulation according to claim 1, characterized in that, The display is also configured to respond to a zoom command for a specified area of ​​the interactive interface, and control the interactive interface to zoom in on the display information of the specified area.

12. A control method for a continuous blood oxygen monitoring system during extracorporeal circulation, characterized in that, The method is applied to the continuous oxygenation monitoring system in extracorporeal circulation as described in any one of claims 1 to 11; the method includes: The oxygen saturation signal of the blood in the vein is monitored by a vein sensor; The blood oxygen saturation signal and hematocrit of the blood in the arterial tubing are monitored by an arterial sensor. The blood flow rate in the tubing of the extracorporeal membrane oxygenation (ECMO) device is monitored using a blood flow sensor. The oxygen concentration of the gas entering the oxygenator is monitored by an oxygen sensor; The carbon dioxide concentration of the gas output from the oxygenator is monitored by a carbon dioxide sensor. The venous oxygen saturation signal and the arterial oxygen saturation signal are converted into digital signals corresponding to venous oxygen saturation and arterial oxygen saturation, respectively, using a spectrometer. The system provides interactive controls via a display, responds to trigger operations applied to the interactive controls, sends interactive instructions corresponding to the interactive controls to the controller, and updates the information displayed in the interactive interface according to the control of the controller. The controller receives the interactive command and executes the corresponding processing; the processing includes controlling the display information of the display; the display information includes information corresponding to at least some monitoring parameters; the monitoring parameters include: venous blood oxygen saturation, arterial blood oxygen saturation, hematocrit, blood flow, oxygen concentration, and carbon dioxide concentration.

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