5results about How to "Improve physical function" patented technology

The invention provides a diabetic patient life management method and system in combination with traditional Chinese medicine knowledge, and relates to the field of medical health data processing, the method comprises the following steps: obtaining multiple groups of sample data, the sample data at least comprising personal information of sample patients and diabetic traditional Chinese medicine syndromes, and the personal information of the sample patients at least comprising diabetes index data; based on the multiple groups of sample data, multiple key traditional Chinese medicine syndrome discrimination units are determined, and a diabetes traditional Chinese medicine syndrome diagnosis scale is generated; based on the multiple groups of sample data, determining music types matched with different diabetes mellitus traditional Chinese medicine syndromes; determining the diabetic traditional Chinese medicine syndrome of the current user based on the personal information of the current user and the filling information of the diabetic traditional Chinese medicine syndrome diagnosis scale; based on the diabetic traditional Chinese medicine syndromes of the current user and the music types matched with different diabetic traditional Chinese medicine syndromes, music, traditional Chinese medicine health maintenance skills and traditional Chinese medicine recipes are recommended, and the method has the advantage of improving the quality of life management of diabetic patients.

The application discloses an engineered exosome targeting human urokinase-type plasminogen activator receptor uPAR and a preparation method and application thereof. Firstly, a high-affinity anti-human uPAR single-domain antibody VHH is prepared; then, a human umbilical cord mesenchymal stem cell engineering cell line expressing a VHH-PTGFRN fusion protein is constructed, and the engineered exosome is prepared and purified by combining three-dimensional hypoxic culture, chemical induction and size-exclusion chromatography technology. The engineered exosome comprises four comparative samples, wherein the core sample Exo^(VHH / miR) can simultaneously display the anti-uPAR VHH on the membrane surface to realize targeted delivery and enrich miR-193b-3p in the chamber to realize gene silencing, and the synergistic effect of the two can efficiently remove the uPAR high-expression senescent cells and inhibit the senescence-associated secretory phenotype SASP. The engineered exosome has the advantages of standardized preparation process, high yield and high purity, strong targeting, excellent curative effect and good safety, and can be used for preparing a treatment preparation for anti-aging and aging-related diseases, and has important clinical application value.

The utility model relates to a welfare cage laying hen house which is characterized in that the welfare cage laying hen house comprises a ground activity area (3), a plurality of activity platforms and a plurality of laying platforms which form at least two layer structures, one layer structure is formed by overlapping the plurality of activity platforms, and the other layer structure is formed by overlapping one or more activity platforms and one or more laying platforms. Or the egg laying platform is formed by stacking a plurality of egg laying platforms; a vertical crossing activity space exists between the two layer structures, and the two layer structures are located on the ground activity area (3) to form a U shape. The laying hens can freely move on any platform between the two layer structures. On the premise that a larger activity space is provided for laying hens, the space height of the henhouse is utilized, a crossed three-dimensional inhabiting platform is provided, the number of the laying hens in unit volume is increased, and the chicken raising cost is reduced.

This invention belongs to the field of biomedical and health care technology. Specifically, this invention relates to a composition of metabiotics and calcium salts and its application. Our unit unexpectedly discovered, through extensive research, that *Lactobacillus delbrueckii* subsp. bulgaricus Lb-87 (… Lactobacillus delbrueckii subsp. Bulgaricus Lb-87 (a metabiotic) can synergistically work with calcium salts to significantly improve the absorption rate of calcium ions in the body, thereby effectively promoting calcium utilization and maintaining normal physiological functions. This discovery provides a new technical path and solution for developing foods, pharmaceuticals, health foods, and dietary supplements with highly efficient calcium absorption-promoting functions and multiple effects.

The present invention provides synthetic compounds having magical biological activity, compositions comprising them, processes for their preparation and their use in the treatment of diseases, symptoms and conditions.