Embodiments of the invention include a method and a device for increasing
blood flow and controlling the temperature of a
mammal by applying a desired pressure to extremities of a
mammal. The device generally includes one or more collapsible and pliant body elements, capable of expanding from a first volume into an expanded second volume so the device can receive a portion of an extremity of the
mammal therein and then be reduced from the expanded second volume into a pressurized third volume to conformably enclose the portion of the extremity. One or more thermal exchange units can be positioned in the one or more collapsible and pliant body elements. Accordingly, the temperature of the extremity of a mammal can be regulated by providing a heated or cooled fluid medium or electric
thermal energy to the one or more thermal exchange units. Next, by evacuating the region in which the extremity is enclosed the contact surface area between the extremity of a mammal and the one or more thermal exchange units is increased, due to the external
atmospheric pressure acting on the pliant body elements against the
skin of the extremity of the mammal. The application of pressure assures that sufficient contact and thermal
heat transfer (heating or cooling) is provided to the extremity of the mammal.