Method for increasing blood flow in or about a cardiac or other vascular or prosthetic structure to prevent thrombosis

a technology of thrombosis and prosthesis, which is applied in the field of apparatus and methods for increasing blood flow in or about a cardiac or other vascular or prosthetic structure to prevent thrombosis, can solve the problems of obliteration and occlusion of the heart, reducing the secretion of the peptide hormone atrial natriuretic factor, and reducing the compliance of the atrial artery, so as to improve the blood flow and prevent thrombo

Active Publication Date: 2012-01-26
THE CLEVELAND CLINIC FOUND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0007]In accordance with another aspect of the present invention, a method is provided for increasing blood flow in a left atrial appendage
[0008](LAA) to prevent thrombosis. One step of the method includes providing an implantable sprayer comprising an elongated tubular body having proximal and distal end portions. The distal end portion includes at least one opening and an anchoring mechanism. The distal end portion of the implantable sprayer is inserted into a cardiac chamber that includes the cardiac structure. The anchoring mechanism is deployed so that the distal end portion of the implantable sprayer is secured in the LAA. The proximal end portion is then anastomosed with a subclavian artery so that blood flows through the elongated tubular body of the implantable sprayer and is sprayed out of the at least one opening to continuously circulate blood in the LAA.
[0009]In accordance with another aspect of the present invention, a method is provided for promoting circulation within a LAA. One step of the method includes providing an implantable sprayer. The implantable sprayer comprises an elongated tubular body having proximal and distal end portions. The distal end portion includes at least one opening and an anchoring mechanism. Next, the distal end portion of the implantable sprayer is inserted into a left atrium that includes the LAA. The anchoring mechanism is then deployed so that the distal end portion of the implantable sprayer is secured in the left atrial appendage. The proximal end portion is anastomosed with a portion of an interatrial septum so that blood is withdrawn from the LAA through the at least one opening and into a right atrium to prevent or mitigate blood stasis in the LAA.

Problems solved by technology

Arrhythmias are abnormal heart rhythms that may cause the heart to function less effectively.
Obliteration and occlusion are controversial because of the uncertain physiological role of the LAA.
Reports have suggested that obliteration of the LAA may decrease atrial compliance and diminish peptide hormone atrial natriuretic factor secretion.
Furthermore, while properly positioned filter devices prevent migration of thrombi into the circulatory system, such devices cannot inhibit thrombus formation within the LAA.

Method used

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  • Method for increasing blood flow in or about a cardiac or other vascular or prosthetic structure to prevent thrombosis
  • Method for increasing blood flow in or about a cardiac or other vascular or prosthetic structure to prevent thrombosis
  • Method for increasing blood flow in or about a cardiac or other vascular or prosthetic structure to prevent thrombosis

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Embodiment Construction

[0031]The present invention relates to apparatus and methods for increasing blood flow in or about a cardiac structure, and more particularly to a method 10 (FIG. 1) and apparatus (FIG. 2) for increasing blood flow in or about a cardiac structure 20 (FIG. 5) or other vascular or prosthetic structure to prevent thrombosis. Certain cardiac structures 20, such as the left atrial appendage 22 (LAA) and implanted prosthetic cardiac valves 24 can lead to thrombus formation as a result of blood stasis on or about the cardiac structures. Current techniques for preventing or mitigating thrombus formation include surgical obliteration of and / or blood flow restriction to such cardiac structures 20. Unlike these techniques, however, the method 10 of the present invention does not restrict blood flow in or about cardiac structures 20. Rather, the present invention enhances or increases blood flow in or about cardiac structures 20. Advantageously, the method 10 of the present invention promotes b...

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Abstract

A method is provided for increasing blood flow in or about a cardiac structure to prevent thrombosis. One step of the method includes providing an implantable sprayer having an elongated tubular body with proximal and distal end portions. The distal end portion includes at least one opening and an anchoring mechanism. The distal end portion of the implantable sprayer is inserted into a cardiac chamber that includes the cardiac structure. The anchoring mechanism is then deployed so that the distal end portion of the implantable sprayer is secured in or about the cardiac structure. Next, the proximal end portion is anastomosed with an artery so that blood flows through the elongated tubular body of the implantable sprayer and is sprayed out of the at least one opening to continuously circulate blood in or about the cardiac structure.

Description

RELATED APPLICATION [0001]This application claims priority from U.S. Provisional Patent Application Ser. No. 61 / 367,472, filed Jul. 26, 2010, the subject matter of which is hereby incorporated by reference in its entirety.FIELD OF THE INVENTION [0002]The present invention relates to apparatus and methods for increasing blood flow in or about a cardiac structure, and more particularly to apparatus and methods for increasing blood flow in or about a cardiac or other vascular or prosthetic structure to prevent thrombosis.BACKGROUND OF THE INVENTION[0003]Arrhythmias are abnormal heart rhythms that may cause the heart to function less effectively. Atrial fibrillation (AF) is the most common abnormal hear rhythm. Research has indicated that as many as ninety-percent of all thrombi formed during AF originate in the left atrial appendage (LAA). The LAA is a remnant of an original embryonic left atrium that develops during the third week of gestation. It is located high on the free wall of l...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61M1/36A61M11/00
CPCA61B17/0057A61B2017/00592A61B2017/00606A61F2002/068A61B2017/00867A61F2/06A61F2/2412A61B2017/00623
Inventor KAPADIA, SAMIR
Owner THE CLEVELAND CLINIC FOUND
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