52 results about "Large artery" patented technology

The present invention is directed to the use of a stented graft having predetermined and sized lateral openings for the treatment of arterial disease at or around the intersection of multiple arteries, thereby ensuring blood flow through such arteries to collateral organs. In particular, the lateral opening of a main stent supporting a main artery has a collar with either at least two detents or inlets spaced about the annular extent thereof. The main collar mates with a collateral collar provided at the proximal end of the collateral stent having the other of at least two detents or inlets spaced about the annular extent thereof at intervals coincident with the inlets or detents on the main collar to mate and lock the main stent to the collateral stent supporting a collateral artery.

A device and method for protecting a blood vessel, and hence bodily tissues, against damage caused by particulate such as an embolus. The device may be a stent, for insertion in a large artery such as the ascending aorta, and may be combined with a filter. In one embodiment, the device includes an outer wire frame rather than a stent. The stent may be made of at least one layer of mesh, which is typically attached or mounted to the arterial wall. Typically only part of the stent is attached (for example at a reinforcing ring structure). Typically the size of the apertures of the mesh at the top portion of the stent is smaller than the bottom portion of the stent. The device and method are particularly useful in preventing blockages of flow to the brain, but have other uses as well. An electric charge may be placed on the device, for example, to prevent blood components from collecting.

A method and apparatus for optimizing cardiac resynchronization therapy are provided. An iterative optimization procedure is performed to test the systolic hemodynamic effects of varying A-V-V timing schemes. The hemodynamic effect is assessed based on a surrogate of stroke volume. The stroke volume surrogate is derived from a sensor signal proportional to the blood pressure in the aorta or a major artery. The A-V-V timing scheme corresponding to the greatest stroke volume, as indicated by the stroke volume surrogate, is identified and automatically programmed to maintain optimal A-V-V settings acutely and chronically.

Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites include a main graft or stent-graft deployable in a main artery and a vent device or stent-graft deployable in a branch artery to maintain blood flow through the main artery and from the main artery to the branch artery. Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites may also include a main graft or stent-graft deployable in the main artery, a chimney graft or stent-graft deployable in both branch artery and the main artery to the branch artery and a gutter-sealing device associated with the chimney graft to prevent flow of blood among the chimney graft, the main graft and a wall of the main artery.

A method and apparatus for optimizing cardiac resynchronization therapy are provided. An iterative optimization procedure is performed to test the systolic hemodynamic effects of varying A-V-V timing schemes. The hemodynamic effect is assessed based on a surrogate of stroke volume. The stroke volume surrogate is derived from a sensor signal proportional to the blood pressure in the aorta or a major artery. The A-V-V timing scheme corresponding to the highest magnitude stroke volume, as indicated by the stroke volume surrogate, is identified and automatically programmed to maintain optimal A-V-V settings acutely and chronically.

A method and apparatus for optimizing cardiac resynchronization therapy are provided. An iterative optimization procedure is performed to test the systolic hemodynamic effects of varying A-V-V timing schemes. The hemodynamic effect is assessed based on a surrogate of stroke volume. The stroke volume surrogate is derived from a sensor signal proportional to the blood pressure in the aorta or a major artery. The A-V-V timing scheme corresponding to the highest magnitude stroke volume, as indicated by the stroke volume surrogate, is identified and automatically programmed to maintain optimal A-V-V settings acutely and chronically.

The invention is a next generation miniature heart assist device developed in order to maintain the blood circulation in patients with severe heart failure, and is applied endovascularly to the large arteries. This device is technically a kind of synchronous servo electric motor using “direct drive technology”. It provides longer battery life and high blood flow. Small volume and very low energy consumption provide a much longer battery life and a high blood flow. As the outer surface of the parts placed into the blood vessel will be completely covered with the endothelial cells and the intima layer of the arteries in time, there will be no foreign surface contacting directly with blood. As a result, no thromboembolic event or any negative effect on the cellular components of blood is expected.

A stand-alone continuous cardiac Doppler pulse monitoring patch provides visual and auditory signals that a pulse is detected or not detected in a human subject. The invention is a small patch with a peel-away adhesive surface that is applied to the skin of the subject, preferably near a large artery. The adhesive surface of the patch includes a conductive medium to enhance transmission and reception of ultrasonic waves. The patch includes an integral power source, transmitters and receivers to send and detect reflected ultrasonic waves, a transducer to convert the reflected waves into an electrical signal, a processor to analyze the signal, a light to indicate the presence and strength of a pulse, and a speaker also to indicate the presence and strength of a pulse. The Doppler effect of waves reflecting from blood pumped from a heart is used to detect a pulse in the subject. The presence of a pulse is analyzed by the processor to determine the frequency and strength of blood flow. The processor causes the light to blink at a rate to indicate the frequency of rhythmic blood flow. In a further embodiment, the processor analyzes the strength of the blood flow and causes the light to increase or decrease in intensity to reflect the strength or weakness of the flow. The processor may also drive a speaker to emit sounds, such as beeps, that indicate the frequency and strength of blood flow. The absence of blood flow may be indicated by the absence of light or sound, or by separate light or auditory signals.

The invention relates to a system for measuring the conduction time of pulse waves between cerebral arteries and cerebral veins. The system comprises a signal acquisition device, a signal processing device and a display device, wherein the signal acquisition device is connected with the signal processing device through a communication interface module; and the output end of the signal processing device is connected with the display device. The cerebral blood flow signal acquisition method comprises the following steps: 1) arranging a fixed probe device with two cerebral blood flow signal acquisition devices; 2) synchronously acquiring cerebral blood flow signals; and 3) exchanging the positions of the two cerebral blood flow signal acquisition devices. The medicinal uses of the system are as follows: 1) synchronously acquiring the cerebral blood flow signals of ipsilateral encephalic large arteries (aorta) and encephalic deep veins of a person to be tested at a resting state; and 2) measuring the time difference of the two cerebral blood flow signals. Through the system provided by the invention, noninvasive detection is realized on the conduction time of pulse waves between the cerebral arteries and the cerebral veins; and the clinical practicality is strong, the stiffness of cerebral arteriolae can be accurately and directly reflected, and the risk of apoplexy is estimated, thus being beneficial for early discovering and preventing cerebral arteriosclerosis of patients.

A stand-alone continuous cardiac Doppler or acoustic pulse monitoring patch provides visual and auditory signals that a pulse or heartbeat is detected or not detected in a human subject. The invention is a small patch with a peel-away adhesive surface that is applied to the skin of the subject, preferably near a large artery. For the Doppler monitor, the patch includes a pad formed of a conductive medium to enhance transmission and reception of ultrasonic waves. For the acoustic monitor, the pad has a sound focusing portion that permits entry of sounds and focuses the sounds toward a microphone, and the pad also has a sound insulating portion surround the sound focusing portion. The patch includes an integral power source. The Doppler patch has transmitters and receivers to send and detect reflected ultrasonic waves and a transducer to convert the reflected waves into an electrical signal. The acoustic patch has a microphone to detect the sound of a heartbeat and a transducer to convert the sound energy into an electrical signal. A processor analyzes the Doppler wave signals or the acoustic signals. A light indicates the presence and strength of a pulse detected from the Doppler wave signals or a heartbeat detected by the microphone. A speaker and a vibrator may also to indicate the presence and strength of a pulse or a heartbeat. The Doppler effect of waves reflecting from blood pumped from a heart is used to detect a pulse in the subject. The presence of a pulse or heartbeat is analyzed by the processor to determine the frequency and strength of blood flow or beating of the heart. The processor causes the light, speaker or vibrator to blink, beep or vibrate at a rate to indicate the frequency of rhythmic blood flow or heartbeat.

A physical phantom reference to control for variability of computed tomography measurement results duplicates the density curve of blood perfusion of contrast material in a healthy aorta or large artery to normalize observed changes in healthy arterial blood perfusion when calculating the reduction in tumor blood perfusion between two examination times. In one embodiment, a plurality of compartments with different concentrations of contrast material corresponding to a density curve of blood perfusion of a healthy tissue are positioned-in a screening field of a CT machine so the CT machine images the compartments when it images the healthy tissue. In another embodiment, a pipe containing fluid receives an injection of contrast material from the injector when the injector injects the contrast material into the patient, the pipe having sections of varying diameter so the sections together correspond to a blood perfusion curve of the contrast material in a healthy tissue.

A FISH detection probe and kit for aortic dissection are provided. The probe comprises a FISH fluorescent probe used for detecting MiR-4769-3P, has-MiR-636, has-MiR-142-3p, has-MiR-425-3p and has-MiR-191-3p FISH fluorescent probe, the nucleotide sequence of which is as follows: SEQ ID NO: 1-5. The kit of the invention can be used for molecular diagnosis of large artery dissection, auxiliary etiological diagnosis of large artery dissection, and differentiation of dissecting and non-dissecting tissues for surgical and pathological judgment of lesion range.

The invention discloses a temperature-responsive supra-molecular copolymer hydrogel embolization material and a preparation method thereof, wherein two monomers such as acrylamide and N-acryloyl chloride glycinamide are copolymerize under the action of an initiator to obtain a polymer gel PNAGA-PAAm, the polymer gel and iohexol are mixed at a high temperature to obtain a uniform mixture, the iohexol-containing hydrogel can be injected into renal artery through a microcatheter in a molten state at a temperature of slightly above the body temperature to embolize the kidney so as to be used for embolizing large arteries, the hydrogel mixture can undergo sol-gel transition at the temperature near body temperature, and the transition is fast. According to the present invention, the iohexol-containing polymer can be developed under X-rays, such that the embolization material can smoothly enter the target site, and the false embolization can be avoided.

The invention discloses a device for preventing and treating atherosclerosis and symptoms thereof by inputting positive energy into a human body. The invention relates to a thermal therapy system, in particular to a device which is used for inputting positive energy into the human body by two approaches of 1, the respiratory tract or 2, the respiratory tract and the human body superficial large artery and / or veins and / or key acupuncture points of an affected part and gradually eliminating atherosclerosis and symptoms thereof. The device has the additional contributions that a new arterial blood low-temperature pathogenic theory is disclosed in another way by theoretical innovation; and the device is used for breaking through the constraint of a conventional theory and indicates the direction for structure innovation of a positive energy input device for preventing atherosclerosis and the like. The device further has the contribution that by setting and controlling an energy output unit of the positive energy input device for preventing atherosclerosis and the like in a unit for outputting heat energy, magnetic energy, optical energy, plant essence energy and the like, the preventing and treating effects of the positive energy input device on atherosclerosis are greatly improved.

The invention discloses an edible fungus processing method. The method comprises the steps as follows: fresh edible fungi and a large artery of pig or ox are used as raw materials, the edible fungi ismade into a semi-finished product through procedures of rinsing, color protecting, slicing, precooking, salting, desalination and the like, the large artery of pig or ox is made into a semi-finishedproduct through procedures of rinsing, deodorization, precooking, taste enhancement with bone soup, cooling, cutting and the like, the semi-finished product of edible fungi and the semi-finished product of large artery of pig or ox are matched in proportion, flavoring and seasoning materials and auxiliary materials are mixed uniformly, and an edible fungus product is prepared. The product has theadvantages of being green, natural, reasonable in nutrient matching, good in flavor and taste, convenient to eat, long in expiration date and the like.

The invention discloses a green wave bandwidth maximization-based artery green wave coordination control timing method. The method comprises the following steps: (1) investigating geometry setting parameters and basic timing parameters at signal intersections of an artery, and calculating conversion distances Di between the intersections; (2) calculating the value ranges and the iterative steps of ideal signal distances to obtain a value set A of the ideal signal distances; (3) partitioning the relative positions of ideal signals, based on the calculating rule of green wave loss, calculating the largest green wave bandwidths GWBj of the artery under all possible ideal signal distance values Aj; (4) selecting the largest value among GWBj as the optimal green bandwidth GWB*, and calculating the green time difference of each intersection so as to obtain a coordination control timing scheme with the largest artery green wave bandwidth.

The invention discloses a method for evaluating collateral vessels and tissue function based on cerebral blood flow, which comprises the following steps of: firstly, registering cerebral blood flow graphs with multiple delay times of a patient diagnosed with major artery occlusion infarction to realize one-to-one correspondence on a spatial anatomical structure; secondly, removing cerebral shellsand extracerebral structures of the cerebral blood flow graphs with multiple delay times after registration, and calculating cerebral blood flow difference graphs with multiple delay times; then, visualizing cerebral collateral blood circulation conditions, and quantifying collateral blood flow related information, such as collateral blood flow distribution range, velocity, flow and the like; andfinally, by combining with the infarction core area of the patient diagnosed with the major artery occlusion infarction, evaluating the ischemic penumbra, such as the size, volume and position of theischemic penumbra.

Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites include a main graft or stent-graft deployable in a main artery and a vent device or stent-graft deployable in a branch artery to maintain blood flow through the main artery and from the main artery to the branch artery. Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites may also include a main graft or stent-graft deployable in the main artery, a chimney graft or stent-graft deployable in both branch artery and the main artery to the branch artery and a gutter-sealing device associated with the chimney graft to prevent flow of blood among the chimney graft, the main graft and a wall of the main artery.

The invention discloses a system and a method for multi-segment large artery stiffness tests. The system comprises a measuring system, a photoelectric pulse sensor, a signal conditioning device, and a signal display device. The measuring system is used to measure the body surface distance between strongest pulsation points of two arterial pulses. The photoelectric pulse sensor comprises a PPG emission light source, a photosensitive reception member, and a constant current source control circuit. The signal conditioning device is formed by an integrated instrument amplifier, a low pass filter, an A / D converter, and a single-chip microcomputer. The system can be used for noninvasive acquisition of photoelectric plethysmography signals of human main superficial large arteries, including common carotid-femoral artery, common carotid-radial artery, and femoral-arteria dorsalis pedis, and realizes rapid detection of pulse wave speed of upper limbs and lower limbs, so as to more accurately and more directly show stiffness conditions of aortas and upper limb and lower limb aortas, and evaluate risks of cardiovascular and cerebrovascular diseases. The system and the method are beneficial for early discovery and prevention of cardiovascular and cerebrovascular diseases.

The invention discloses a heating device helpful in eliminating atherosclerosis and activating function of human body. The device comprises a carrier, and a thermal energy unit and a magnetic energy unit which are positioned on the carrier, wherein the thermal energy unit is used for the realizing purposes of (1) eliminating the process of forming atherosclerosis caused by fat point accumulation in directional artery, (2) promoting the melting of the fat accumulated in the artery, (3) gradually eliminating the atherosclerosis and related diseases; the magnetic energy unit is used for realizing the following purposes: (1) assisting the thermal energy in removing the salt waste in atherosclerotic plaque; (2) copying the benign information energy in benign information source to the blood for taking effect, (3) positioning a heater arbitrarily on the superficial large artery blood vessels and / or veins and / or lymphatic vessels and / or ashi acupuncture points of the partial disease, with the help of a second magnet or magnetic material and underwear; the carrier further comprises a benign information unit, through the information of treatment based on syndrome differentiation and medicinal guide (heat), twice effect with half effort can be realized.

A stand-alone continuous cardiac Doppler pulse monitoring patch provides visual and auditory signals that a pulse is detected or not detected in a human subject. The invention is a small patch with a peel-away adhesive surface that is applied to the skin of the subject, preferably near a large artery. The adhesive surface of the patch includes a conductive medium to enhance transmission and reception of ultrasonic waves. The patch includes an integral power source, transmitters and receivers to send and detect reflected ultrasonic waves, a transducer to convert the reflected waves into an electrical signal, a processor to analyze the signal, a light to indicate the presence and strength of a pulse, and a speaker also to indicate the presence and strength of a pulse. The Doppler effect of waves reflecting from blood pumped from a heart is used to detect a pulse in the subject. The presence of a pulse is analyzed by the processor to determine the frequency and strength of blood flow. The processor causes the light to blink at a rate to indicate the frequency of rhythmic blood flow. In a further embodiment, the processor analyzes the strength of the blood flow and causes the light to increase or decrease in intensity to reflect the strength or weakness of the flow. The processor may also drive a speaker to emit sounds, such as beeps, that indicate the frequency and strength of blood flow. The absence of blood flow may be indicated by the absence of light or sound, or by separate light or auditory signals.

The invention discloses an anastomotic buckle for aorta and an artificial blood vessel assembly using the same, relates to the technical field of medical devices, and solves the existing technology of inconvenient operation and difficult adjustment when knotting and fixing the collar of an artificial blood vessel with silk threads (or ribbons) question. The anastomotic buckle for aorta according to the present invention comprises: a buckle body, the buckle body is an annular opening structure, and the first instrument operation holes are respectively arranged on the two sides of the opening on the buckle body; one end of the buckle body There is a first fastening part, and a second fastening part is provided at the other end. The first fastening part and the second fastening part are inserted and locked together, so that the anastomotic buckle for the aorta can be set and fixed on the artificial The outer side of the loop of the blood vessel; the more the overlapping parts of the first fastening part and the second fastening part are inserted and locked, the smaller the diameter of the anastomotic buckle for the aorta; the first fastening part and the second fastening part The less overlapping parts are interfitted and locked, the larger the diameter of the anastomotic buckle for the aorta is.

The present invention relates to at least three orifices which are situated at the junction level of the proximal end close to the heart and the distal end of the medical device and on the cuffed distal end, in order to ensure control of a potential thromboembolism risk, after implantation of the medical device which is used for the purpose of palliative treatment and / or treatment without developing pulmonary hypertension in patients of all age groups who have human heart defects, particularly congenital heart defects, secondary increased pulmonary blood flow and pulmonary hypertension risk; and preparing the left ventricular for systemic circulation in case of development of right ventricular failure following atrial “switch” in patients who have transposition of large arteries with a left ventricular being subjected to involution—to the main pulmonary artery.

The present invention discloses a magnesium alloy renal artery stent and relates to the technical field of medical devices. The magnesium alloy renal artery stent comprises a first support ring frameand a second support ring frame, support sheets are embedded in axial fixing strips, convex belts are arranged on outer surfaces of the first support ring frame and the second support ring frame, anda flexible net is fixedly connected to one side of the second support ring frame. The first support ring frame and the second support ring frame made of magnesium alloy are arranged, the renal arteryintravascular stent can be degraded in blood vessels and can effectively reduce possibility of problems of endangium hyperplasia, restenosis, late thrombus, etc., the flexible net is arranged to avoidrestenosis of a joint of the renal artery blood vessels and major artery blood vessels, the first supporting ring frame and the second supporting ring frame do not need to extend into the major artery blood vessels, therefore normal blood transportation of the major artery blood vessels is not affected, and the convex belts are arranged to play an effect of preventing the first supporting ring frame and the second supporting ring frame from deviating to a certain degree.

Disclosed herein is a delivery catheter having a three-dimensional curvature that facilitates access to the RAA from the inferior vena cava, positioning the distal end of the catheter so that the puncture site within the RAA is approximately parallel to the plane of the pericardial cavity, orienting the puncture device to avoid Orientation of the right coronary artery, aorta, pulmonary artery, and other structures to prevent "bystander" injury to these structures and provide sufficient rigidity to penetrate the wall of the RAA into the pericardial cavity.