49 results about "Large artery" patented technology

A method and apparatus for optimizing cardiac resynchronization therapy are provided. An iterative optimization procedure is performed to test the systolic hemodynamic effects of varying A-V-V timing schemes. The hemodynamic effect is assessed based on a surrogate of stroke volume. The stroke volume surrogate is derived from a sensor signal proportional to the blood pressure in the aorta or a major artery. The A-V-V timing scheme corresponding to the greatest stroke volume, as indicated by the stroke volume surrogate, is identified and automatically programmed to maintain optimal A-V-V settings acutely and chronically.

Methods, compositions, and kits for repairing damaged myocardium and/or myocardial cells including the administration cytokines are disclosed and claimed. Methods and compositions for the development of large arteries and vessels are also disclosed and claimed. The present application also discloses and claims methods and media for the growth, expansion, and activation of human cardiac stem cells.

Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites include a main graft or stent-graft deployable in a main artery and a vent device or stent-graft deployable in a branch artery to maintain blood flow through the main artery and from the main artery to the branch artery. Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites may also include a main graft or stent-graft deployable in the main artery, a chimney graft or stent-graft deployable in both branch artery and the main artery to the branch artery and a gutter-sealing device associated with the chimney graft to prevent flow of blood among the chimney graft, the main graft and a wall of the main artery.

A stand-alone continuous cardiac Doppler pulse monitoring patch provides visual and auditory signals that a pulse is detected or not detected in a human subject. The invention is a small patch with a peel-away adhesive surface that is applied to the skin of the subject, preferably near a large artery. The adhesive surface of the patch includes a conductive medium to enhance transmission and reception of ultrasonic waves. The patch includes an integral power source, transmitters and receivers to send and detect reflected ultrasonic waves, a transducer to convert the reflected waves into an electrical signal, a processor to analyze the signal, a light to indicate the presence and strength of a pulse, and a speaker also to indicate the presence and strength of a pulse. The Doppler effect of waves reflecting from blood pumped from a heart is used to detect a pulse in the subject. The presence of a pulse is analyzed by the processor to determine the frequency and strength of blood flow. The processor causes the light to blink at a rate to indicate the frequency of rhythmic blood flow. In a further embodiment, the processor analyzes the strength of the blood flow and causes the light to increase or decrease in intensity to reflect the strength or weakness of the flow. The processor may also drive a speaker to emit sounds, such as beeps, that indicate the frequency and strength of blood flow. The absence of blood flow may be indicated by the absence of light or sound, or by separate light or auditory signals.

The invention relates to a system for measuring the conduction time of pulse waves between cerebral arteries and cerebral veins. The system comprises a signal acquisition device, a signal processing device and a display device, wherein the signal acquisition device is connected with the signal processing device through a communication interface module; and the output end of the signal processing device is connected with the display device. The cerebral blood flow signal acquisition method comprises the following steps: 1) arranging a fixed probe device with two cerebral blood flow signal acquisition devices; 2) synchronously acquiring cerebral blood flow signals; and 3) exchanging the positions of the two cerebral blood flow signal acquisition devices. The medicinal uses of the system are as follows: 1) synchronously acquiring the cerebral blood flow signals of ipsilateral encephalic large arteries (aorta) and encephalic deep veins of a person to be tested at a resting state; and 2) measuring the time difference of the two cerebral blood flow signals. Through the system provided by the invention, noninvasive detection is realized on the conduction time of pulse waves between the cerebral arteries and the cerebral veins; and the clinical practicality is strong, the stiffness of cerebral arteriolae can be accurately and directly reflected, and the risk of apoplexy is estimated, thus being beneficial for early discovering and preventing cerebral arteriosclerosis of patients.

A physical phantom reference to control for variability of computed tomography measurement results duplicates the density curve of blood perfusion of contrast material in a healthy aorta or large artery to normalize observed changes in healthy arterial blood perfusion when calculating the reduction in tumor blood perfusion between two examination times. In one embodiment, a plurality of compartments with different concentrations of contrast material corresponding to a density curve of blood perfusion of a healthy tissue are positioned-in a screening field of a CT machine so the CT machine images the compartments when it images the healthy tissue. In another embodiment, a pipe containing fluid receives an injection of contrast material from the injector when the injector injects the contrast material into the patient, the pipe having sections of varying diameter so the sections together correspond to a blood perfusion curve of the contrast material in a healthy tissue.

A FISH detection probe and kit for aortic dissection are provided. The probe comprises a FISH fluorescent probe used for detecting MiR-4769-3P, has-MiR-636, has-MiR-142-3p, has-MiR-425-3p and has-MiR-191-3p FISH fluorescent probe, the nucleotide sequence of which is as follows: SEQ ID NO: 1-5. The kit of the invention can be used for molecular diagnosis of large artery dissection, auxiliary etiological diagnosis of large artery dissection, and differentiation of dissecting and non-dissecting tissues for surgical and pathological judgment of lesion range.

The invention discloses a temperature-responsive supra-molecular copolymer hydrogel embolization material and a preparation method thereof, wherein two monomers such as acrylamide and N-acryloyl chloride glycinamide are copolymerize under the action of an initiator to obtain a polymer gel PNAGA-PAAm, the polymer gel and iohexol are mixed at a high temperature to obtain a uniform mixture, the iohexol-containing hydrogel can be injected into renal artery through a microcatheter in a molten state at a temperature of slightly above the body temperature to embolize the kidney so as to be used for embolizing large arteries, the hydrogel mixture can undergo sol-gel transition at the temperature near body temperature, and the transition is fast. According to the present invention, the iohexol-containing polymer can be developed under X-rays, such that the embolization material can smoothly enter the target site, and the false embolization can be avoided.

The invention discloses a device for preventing and treating atherosclerosis and symptoms thereof by inputting positive energy into a human body. The invention relates to a thermal therapy system, in particular to a device which is used for inputting positive energy into the human body by two approaches of 1, the respiratory tract or 2, the respiratory tract and the human body superficial large artery and/or veins and/or key acupuncture points of an affected part and gradually eliminating atherosclerosis and symptoms thereof. The device has the additional contributions that a new arterial blood low-temperature pathogenic theory is disclosed in another way by theoretical innovation; and the device is used for breaking through the constraint of a conventional theory and indicates the direction for structure innovation of a positive energy input device for preventing atherosclerosis and the like. The device further has the contribution that by setting and controlling an energy output unit of the positive energy input device for preventing atherosclerosis and the like in a unit for outputting heat energy, magnetic energy, optical energy, plant essence energy and the like, the preventing and treating effects of the positive energy input device on atherosclerosis are greatly improved.

The invention discloses an edible fungus processing method. The method comprises the steps as follows: fresh edible fungi and a large artery of pig or ox are used as raw materials, the edible fungi ismade into a semi-finished product through procedures of rinsing, color protecting, slicing, precooking, salting, desalination and the like, the large artery of pig or ox is made into a semi-finishedproduct through procedures of rinsing, deodorization, precooking, taste enhancement with bone soup, cooling, cutting and the like, the semi-finished product of edible fungi and the semi-finished product of large artery of pig or ox are matched in proportion, flavoring and seasoning materials and auxiliary materials are mixed uniformly, and an edible fungus product is prepared. The product has theadvantages of being green, natural, reasonable in nutrient matching, good in flavor and taste, convenient to eat, long in expiration date and the like.

The invention discloses a method for evaluating collateral vessels and tissue function based on cerebral blood flow, which comprises the following steps of: firstly, registering cerebral blood flow graphs with multiple delay times of a patient diagnosed with major artery occlusion infarction to realize one-to-one correspondence on a spatial anatomical structure; secondly, removing cerebral shellsand extracerebral structures of the cerebral blood flow graphs with multiple delay times after registration, and calculating cerebral blood flow difference graphs with multiple delay times; then, visualizing cerebral collateral blood circulation conditions, and quantifying collateral blood flow related information, such as collateral blood flow distribution range, velocity, flow and the like; andfinally, by combining with the infarction core area of the patient diagnosed with the major artery occlusion infarction, evaluating the ischemic penumbra, such as the size, volume and position of theischemic penumbra.

The invention discloses a system and a method for multi-segment large artery stiffness tests. The system comprises a measuring system, a photoelectric pulse sensor, a signal conditioning device, and a signal display device. The measuring system is used to measure the body surface distance between strongest pulsation points of two arterial pulses. The photoelectric pulse sensor comprises a PPG emission light source, a photosensitive reception member, and a constant current source control circuit. The signal conditioning device is formed by an integrated instrument amplifier, a low pass filter, an A/D converter, and a single-chip microcomputer. The system can be used for noninvasive acquisition of photoelectric plethysmography signals of human main superficial large arteries, including common carotid-femoral artery, common carotid-radial artery, and femoral-arteria dorsalis pedis, and realizes rapid detection of pulse wave speed of upper limbs and lower limbs, so as to more accurately and more directly show stiffness conditions of aortas and upper limb and lower limb aortas, and evaluate risks of cardiovascular and cerebrovascular diseases. The system and the method are beneficial for early discovery and prevention of cardiovascular and cerebrovascular diseases.

The invention discloses a heating device helpful in eliminating atherosclerosis and activating function of human body. The device comprises a carrier, and a thermal energy unit and a magnetic energy unit which are positioned on the carrier, wherein the thermal energy unit is used for the realizing purposes of (1) eliminating the process of forming atherosclerosis caused by fat point accumulation in directional artery, (2) promoting the melting of the fat accumulated in the artery, (3) gradually eliminating the atherosclerosis and related diseases; the magnetic energy unit is used for realizing the following purposes: (1) assisting the thermal energy in removing the salt waste in atherosclerotic plaque; (2) copying the benign information energy in benign information source to the blood for taking effect, (3) positioning a heater arbitrarily on the superficial large artery blood vessels and/or veins and/or lymphatic vessels and/or ashi acupuncture points of the partial disease, with the help of a second magnet or magnetic material and underwear; the carrier further comprises a benign information unit, through the information of treatment based on syndrome differentiation and medicinal guide (heat), twice effect with half effort can be realized.

The present invention relates to at least three orifices which are situated at the junction level of the proximal end close to the heart and the distal end of the medical device and on the cuffed distal end, in order to ensure control of a potential thromboembolism risk, after implantation of the medical device which is used for the purpose of palliative treatment and/or treatment without developing pulmonary hypertension in patients of all age groups who have human heart defects, particularly congenital heart defects, secondary increased pulmonary blood flow and pulmonary hypertension risk; and preparing the left ventricular for systemic circulation in case of development of right ventricular failure following atrial “switch” in patients who have transposition of large arteries with a left ventricular being subjected to involution—to the main pulmonary artery.

The present invention discloses a magnesium alloy renal artery stent and relates to the technical field of medical devices. The magnesium alloy renal artery stent comprises a first support ring frameand a second support ring frame, support sheets are embedded in axial fixing strips, convex belts are arranged on outer surfaces of the first support ring frame and the second support ring frame, anda flexible net is fixedly connected to one side of the second support ring frame. The first support ring frame and the second support ring frame made of magnesium alloy are arranged, the renal arteryintravascular stent can be degraded in blood vessels and can effectively reduce possibility of problems of endangium hyperplasia, restenosis, late thrombus, etc., the flexible net is arranged to avoidrestenosis of a joint of the renal artery blood vessels and major artery blood vessels, the first supporting ring frame and the second supporting ring frame do not need to extend into the major artery blood vessels, therefore normal blood transportation of the major artery blood vessels is not affected, and the convex belts are arranged to play an effect of preventing the first supporting ring frame and the second supporting ring frame from deviating to a certain degree.

The invention relates to the technical field of biological experiments, in particular to a method for analyzing lipid plaque content by fixing major arteries of rabbits. The method comprises the following steps: A, selection of raw materials; B, arterial choice; C, artery shaping: washing an artery sample clean, and soaking the artery sample in a pre-prepared paraformaldehyde stationary liquid for24 hours; D, fat marking: taking out the shaped artery sample, splitting the artery sample from top to bottom, and dyeing the lipid plaques by adopting a Sudan IV dyeing method; E, preparing of a sample plate: adhering a black double-sided adhesive tape to the transparent sample plate, and adhering the dyed artery sample to the surface layer of the black double-sided adhesive tape; and F, scanning analysis. According to the invention, a proper fixing mode is adopted, the artery can be quickly flattened, so that a clear artery inner wall lipid plaque map can be obtained, shaping of the arteries by adopting the paraformaldehyde stationary liquid are fat marking by a Sudan IV coloring agent are completed in order, the arteries can be prevented from curling or being unobviously distinguishedby using the sticking mode, and the arteries can be rapidly and comprehensively scanned by using the finally prepared sample plate, so that the rabbit artery fixing is simplified, and the lipid content analysis efficiency is improved.

The invention, which belongs to the field of medical equipment, especially relates to a cuff device for isolating a main artery inner wall aneurysm cavity and a using method thereof. The cuff device comprises a foldable tubular cuff, a cuff release controller and a monitoring device. A connecting pipe is communicated to the tail end of the foldable tubular cuff. The cuff release controller includes a cuff accommodating cavity and a cuff releaser. The foldable tubular cuff is arranged into the cuff accommodating cavity after being folded and deformed along the long axis of the tubular structure; and the cuff releaser releases the foldable tubular cuff out of the cuff accommodating cavity. The monitoring device includes a cuff pressure monitoring device, a main artery blood pressure monitoring device and a cuff pressure manager. After the cuff device is implanted, fluid is injected through the cuff release controller to enable the cuff device to be expanded into a tubular structure, so that a tumor cavity is isolated; the fluid is extracted through the cuff releaser to enable the cuff device to shrink, so that the cuff device is taken out. Therefore, problems that the existing metalcovered stent cannot be taken out after being implanted and the price of the metal covered stent is high are solved.

The invention discloses a micro needle-shaped electrode for identifying arteries and veins in an operation. The micro needle-shaped electrode comprises the following steps: measuring blood sample saturation values of main arteries, middle arteries and small arteries of normal adult monkeys; measuring blood sample saturation values of main veins, middle veins and small veins, respectively measuring two main arteries, two middle arteries and two small arteries; simultaneously measuring two main veins, two middle veins, two small veins, surgically anatomizing spermatocordia veins; measuring each vein and artery, measuring the blood oxygen saturation degree of each artery and vein, and statistically analyzing arterial and venous differences, and counting the difference between the artery average value and the vein average value, and judging whether the measured value has comparability and overlapping. According to the micro needle-shaped electrode designed according to the arteriovenous blood oxygen saturation degree principle, arteries and veins can be effectively distinguished in an operation by noninvasively detecting the blood oxygen saturation degree in a blood vessel, the micro needle-shaped electrode is used for distinguishing arteries and veins in a varicocele operation, operation accidental injuries can be effectively reduced, and the postoperative effect can be effectively improved.

Disclosed delivery catheters have a three-dimensional curvature that facilitates reaching the RAA from the inferior vena cava, positioning the distal end of the catheter generally parallel to the plane of the pericardial space at the puncture location within the RAA, orienting the puncturing device in a direction that avoids the right coronary artery, aorta, pulmonary artery, and other structuresto prevent bystander injury to such structures, and provides sufficient rigidity to puncture through a wall of the RAA into the pericardial space.