19 results about "Ascitic fluid" patented technology

The invention provides a postoperative bleeding risk monitoring method and system for a hepatobiliary patient. The method comprises the following steps: collecting real-time multi-modal data; constructing an LSTM-CNN hybrid model by using the time-frequency decomposition features, and obtaining a local tissue hypoxia index and a vasomotor function anomaly probability; the low-frequency impedance change rate and the albumin level are fused through a random forest algorithm, and the ascites occurrence probability and the effusion amount predicted value are obtained; and generating a bleeding point positioning coordinate and a thermodynamic diagram risk grade. And calculating a comprehensive bleeding risk probability and positioning a bleeding area. And generating graded early warning signals and recommending personalized treatment schemes or nursing suggestions. According to the invention, the LSTM-CNN hybrid model, the random forest algorithm and the three-dimensional convolutional neural network are adopted to deeply extract different data features, so that the limitation of single index evaluation is avoided. A causal relationship model is established through the Bayesian network, and the comprehensive risk probability calculation preciseness is improved; the early warning threshold is dynamically adjusted by combining the individual characteristics of the patient, and the traditional problem of easy misjudgment is solved.

The invention discloses a puncture needle for improving the safety and isolation effect of artificial ascites puncture. The puncture needle comprises a hose, a rubber plug, a communicating pipe, a needle body, a needle holding handle and a butterfly wing fixator. The hose is of a venous indwelling needle structure, and the rubber plug is fixedly connected to one end of the hose. The communicating pipe is communicated with the other end of the hose to form a medicine conveying channel. The needle body comprises a steel needle and a soft sleeve wrapping the periphery of the steel needle, the needle holding handle is detachably connected with the needle body, and an isolation plug is arranged in the needle holding handle. And the isolation plug is pulled out together with the steel needle when the needle holding handle is pulled out so as to cover and protect the steel needle. The butterfly wing fixator is arranged at the joint of the needle holding handle and the needle body and comprises a butterfly wing piece and a hydrophilic gel pad fixed to the contact face of the butterfly wing piece and the human skin. The puncture safety in liver cancer ablation treatment is remarkably improved, the risks of mistaken puncture and inaccurate puncture depth are reduced, damage to surrounding important organs and blood vessels is reduced, and the safety and effectiveness of treatment are improved.

The utility model relates to the technical field of infectious diseases, in particular to a hepatopathy ascites aspirator which is matched with an aspiration mechanism to collect hepatopathy ascites, and two collection boxes are arranged to avoid stopping the aspiration work during cleaning, so that the working efficiency is improved, and the practicability is higher. A box door is hinged to the working box, a suction mechanism is arranged on the working box and comprises a pump body, the input end of the pump body communicates with a first communicating pipe, the first communicating pipe communicates with a second communicating pipe, a needle head is arranged on the second communicating pipe, and the output end of the pump body communicates with a third communicating pipe; and two fourth communicating pipes are symmetrically installed on the third communicating pipe in a communicating mode, valves are arranged on the two fourth communicating pipes, two collecting boxes are symmetrically installed on the working box in a sliding mode, the top ends of the two collecting boxes communicate with the two fourth communicating pipes correspondingly, and first observation windows are formed in the two collecting boxes correspondingly.

V1a RECEPTOR PARTIAL AGONISTS AND METHODS OF USE SOLUTION: The present invention provides novel partial V1a agonists for partial activation of V1a receptors. The partial V1a agonists have therapeutic indices of at least 20 (e.g., at least 30, at least 40, at least 50, at least 60, at least 70, at least 80, at least 90, at least 100). Also provided is a method of treating liver fibrosis, hepatocirrhosis, portal hypertension, peritoneal fluid, esophageal varices, fundic varices, hemorrhage, arterial hypotension, and / or hepatorenal syndrome, comprising administering to a subject in need thereof a therapeutically effective dose of a composition comprising one or more of the disclosed partial V1a agonists, optionally in combination with a V2 antagonist.SELECTED DRAWING: None

The application discloses a peritoneal cavity drainage negative pressure adsorption device with detection function, and relates to the field of peritoneal cavity drainage adsorption devices. The application provides a peritoneal cavity drainage negative pressure adsorption device with detection function which can keep a puncture needle stable. The peritoneal cavity drainage negative pressure adsorption device with detection function comprises a U-shaped sliding frame, a sliding plate is slidably connected to the U-shaped sliding frame, symmetrical bases are fixedly connected to the U-shaped sliding frame, a supporting frame is slidably connected to the sliding plate, a puncture needle is arranged between the supporting frame and the sliding plate, an infrared sensor is installed on the supporting frame, a screw rod is fixedly connected to the supporting frame, and a nut is threadedly connected to the screw rod. The turbidity of ascitic fluid drawn out is detected by the infrared sensor, so that the optimal puncture position is determined. The fixing of the puncture needle is completed by the supporting frame, the screw rod and the nut, the discomfort of a patient caused by movement of the puncture needle during puncture can be reduced, and local serious bleeding caused by movement of the puncture needle is prevented.

An indwelling pleural catheter system comprises an indwelling catheter device (2) comprising a catheter tube (7) with a fenestrated distal end (7A) configured to reside in the pleural cavity of a subject and a connection hub (10) fluidically coupled to a proximal end (7B) of the catheter tube, a skin anchoring member (3) to anchor the connection hub (10) to the skin of the subject, and optionally a detachable ambulatory suction module (4) configured for detachable attachment to the connection hub (10). The suction module (4) comprises a fluid inlet (19) configured for fluidic coupling to the catheter tube (7) through the connection hub (10) and a fluid outlet (20) configured for detachable fluidic coupling to a pleural fluid drainage system (5) to drain pleural fluid through the detachable ambulatory suction module. The detachable ambulatory suction module is configured to exert a negative pressure in the catheter tube upon detachment of the pleural fluid drainage system from the suction module. Treatment of pleural effusion using the system of the invention is described. An indwelling catheter system for draining fluid from the peritoneal cavity, and methods of treating ascites, is also described.

This invention provides a reusable ascites drainage device, comprising: a drainage seat, a drainage tube, a negative pressure assembly, and a collection container; one end of the drainage tube is connected to the drainage seat, and the negative pressure assembly and the collection container are both connected to the other end of the drainage tube; the negative pressure assembly is used to generate negative pressure within the drainage tube, allowing ascites fluid from the drainage seat to enter the drainage tube; the collection container is used to collect the ascites fluid draining from the drainage tube; the drainage seat includes an annular shell, one end of which is provided with a self-sealing soft body for sealing; one end of the drainage tube is connected to a puncture needle, which is inserted into and penetrates the self-sealing soft body into the annular shell. This embodiment reduces tissue damage from repeated punctures, improves patient comfort, enhances the precise control of negative pressure within the drainage tube, protects tissues near the drainage seat from damage, and reduces the risk of abdominal infection.

The invention discloses an enteral nutrition infusion regulation and control method and system for patients with cirrhosis ascites, and relates to the technical field of medicines.The enteral nutrition infusion regulation and control method comprises the following steps that basic illness state information, intestinal function information and laboratory nutrition indexes of the patients with cirrhosis ascites are collected; performing analysis to obtain grading characteristics of the basic illness state information, absorption capacity characteristics of the intestinal function information and supply and demand characteristics of the laboratory nutrition indexes, calculating individual enteral nutrition demand parameters of the patient based on the grading characteristics, the absorption capacity characteristics and the supply and demand characteristics, and generating an initial enteral nutrition infusion scheme. Based on comprehensive evaluation of basic illness conditions, intestinal functions and laboratory indexes, nutritional requirement parameters are calculated in combination with correction coefficients, and it is ensured that an initial scheme adapts to individual characteristics of patients. Through set dose trial verification and real-time monitoring, abnormal types such as intestinal tolerance, liquid electrolyte balance, nutritional state and special illness conditions can be identified in time.

The utility model relates to the technical field of digestive system department instruments, and particularly discloses an ascites drainage pipeline fixator which comprises a first positioning seat, a clamping plate is arranged on one side of the first positioning seat, and the clamping plate is connected with the first positioning seat through a spring piece. The second positioning seat is hinged to one side of the first positioning seat, the side, away from the hinged position of the first positioning seat, of the second positioning seat is rotationally connected with a positioning plate, and the positioning plate is connected with the first positioning seat through a fixing piece; the pipeline groove is formed between the first positioning seat and the second positioning seat; in the ascites drainage process, accumulated pipelines can be fixed and guided, winding, pressing, excessive bending and the like are reduced, ascites are drained into the drainage bag through the pipelines to be collected, and when the ascites are large in accumulated liquid amount, thick or not prone to flowing out naturally, the ascites can be sucked out through connection of the negative pressure suction pipe and the connecting pipe. Negative pressure is generated in a corresponding drainage bag connected with the drainage bag connector, the amount of effusion in the abdominal cavity can be rapidly reduced, and abdominal distension and discomfort of a patient are relieved.

The adjustable and controllable ascites drainage device based on the buoy principle comprises a transparent flow velocity device, a containing scale strip is arranged on the front face of the flow velocity device, a cavity is formed in the flow velocity device, a buoy capable of floating on ascites is arranged in the cavity, and a dripping opening used for forming water drops is formed in the upper wall of the cavity. The upper end of the flow velocity device is provided with a liquid inlet used for being connected with an abdominal cavity drainage tube, the liquid inlet is communicated with the dripping opening, the lower end of the flow velocity device is provided with an infusion tube, the infusion tube is a hard tube, the outer end of the infusion tube is connected with a container, the infusion tube is provided with a butterfly valve, a turnable sealing plate is arranged in the butterfly valve, and a knob is arranged outside the butterfly valve. When the knob rotates reversely, the sealing plate is turned over and closed to reduce the flow velocity of ascites. According to the adjustable and controllable ascites drainage device, the ascites drainage speed can be controlled, adverse reactions such as hypotension caused by too high ascites drainage speed are avoided, and the situation that ascites cannot be drained successfully due to too low ascites drainage speed is avoided.

The utility model belongs to the field of ascites aspirators, and particularly relates to a hepatopathy ascites aspirator. The device comprises a liquid storage bottle with an upward bottle opening, the bottle opening of the liquid storage bottle is detachably sleeved with a connecting cover, a liquid suction pipe independently penetrates through the side wall of the connecting cover, an adjuster used for adjusting the flow speed of ascites is installed on the liquid suction pipe, and a puncture needle is installed at the liquid inlet end of the liquid suction pipe. A locking assembly used for locking the liquid suction pipe is arranged between the liquid suction pipe and the connecting cover, an air suction assembly used for sucking air in the liquid storage bottle is arranged at the top of the connecting cover, an insertion rod used for being independently installed in the liquid storage bottle in a penetrating mode is vertically fixed to the air suction assembly, and a clamping groove used for clamping a pipe body at the liquid outlet end of the liquid suction pipe is formed in the insertion rod. An air outlet pipe communicated with the connecting cover is connected to the side wall of the connecting cover, and a valve is installed on the air outlet pipe. Therefore, long-time manual operation is not needed, the workload of medical staff can be reduced, and the medical staff can be more relaxed.

The invention relates to the technical field of medical apparatus and instruments, and discloses an abdominal cavity drainage tube with an inflatable airbag, which comprises a tube body for draining liquid in an abdominal cavity, an airbag configured on the tube body, an inflatable component communicated with the airbag, and an adaptive structure capable of adapting to the change of the internal pressure of the abdominal cavity to maintain the effect that the airbag is attached to the inner wall of the abdominal cavity; by means of the integrally-formed structure of the tube body and the inflation tube and the cooperation of the flat inflation air bag with the anti-skid points, the drainage tube can be evenly attached to the inner wall of the abdominal cavity to form mechanical clamping and friction fixing, displacement and slippage of the tube body are avoided, meanwhile, wound gaps are blocked, ascites leakage is eradicated, and the problems that a traditional drainage tube is poor in fixation and seepage is solved; and the pressure sensor is linked with the processing equipment and the inflating equipment, so that support is provided for dynamic regulation and control of the pressure of the air bag, the device is adaptive to the intraperitoneal pressure change and the whole drainage process working condition, instant automatic air supply can be achieved when the pressure is lower than a threshold value, the device is adaptive to different opening and fitting requirements, and the safety, convenience and suitability of the peritoneal drainage operation are effectively improved.

This invention provides a pressure-adjusting, leak-proof ascites puncture and drainage device, belonging to the field of medical supplies. It includes: a drainage tube; and a leak-proof component. The leak-proof component includes a connecting cap that can be placed on the skin. A polyethylene film that can be adhered to the skin is fixed on the connecting cap. A rubber ring is installed in the mounting hole. After the drainage tube passes through the rubber ring, it can seal against the inner wall of the rubber ring. A pressure-adjusting mechanism is installed on the connecting cap. A connecting ring is fixed to the outside of the connecting cap, and an adhesive ring that adheres to the skin is fixed to the bottom of the connecting ring. This invention increases the pressure between the rubber ring and the skin by adhering the polyethylene film to the skin, thereby further improving the sealing between the rubber ring and the skin. Simultaneously, the adhesion of the polyethylene film to the skin also provides a sealing effect, thus ensuring the seal between the connecting cap and the skin and effectively preventing leakage between the skin and the connecting cap.

The present invention relates to an improved internal drainage tube for ascites drainage, which makes it possible to discharge ascites in the abdominal cavity through urine through the bladder and greatly ensures the fixing force to the bladder wall as a reference that distinguishes the area between the abdominal cavity and the bladder.

The utility model discloses a drainage device for ascites discharge of tumor patients, which comprises a drainage bag, a connecting piece is arranged at the top of the drainage bag, a detachable drainage tube is arranged in the connecting piece, the drainage tube is communicated with an inner cavity of the drainage bag through the connecting piece, and a communicating tube communicated with the inner cavity of the drainage bag is mounted at the top of the drainage bag. The top end of the communicating pipe penetrates through and extends out of the drainage bag, a flow guide pipe communicated with an inner cavity of the communicating pipe is installed at the top end of the communicating pipe, the bottom end of the communicating pipe is sealed, and a first communicating hole communicated with the inner cavity of the communicating pipe is formed in the upper portion of the side face of the communicating pipe. The drainage device for ascites drainage of the tumor patient can be used for drainage of ascites and collection of ascites, medical staff can conveniently judge whether postoperative bleeding, digestive juice leakage and the like exist in the abdominal cavity or not according to information such as the ascites color and the drainage amount, meanwhile, the drainage device can conveniently sample the collected ascites, and the drainage effect is good. And the ascites characteristics can be conveniently detected by medical staff.

The invention relates to a culture method of TIL from pleural effusion and / or ascites. Specifically, the invention provides the in-vitro culture method of the pleural effusion and / or ascites derived TIL, and the method comprises the following steps: 1) obtaining TIL seed cells from pleural effusion and / or ascites, and 2) sorting the TIL seed cells to obtain intermediate cells which are CD45RA-cells, CD39 + cells, or CD45RA-CD39 + cells.

The utility model relates to an ascitic fluid drainage equipment for internal medicine, belongs to drainage equipment technical field, in order to solve the momentary change of negative pressure pump suction load, there is the case of unstable negative pressure, will cause the rate of control loss of electrolyte in vivo, is not favorable for the stable recovery of patient's physical index problem, the invention includes negative pressure equipment, the one side of negative pressure equipment is connected with the collecting bottle, the one end of collecting bottle is connected with liquid inlet pipe, the inside of liquid inlet pipe is installed with negative pressure pressure sensor, the outer surface of liquid inlet pipe is sleeved with telescopic hose, and the one end of telescopic hose is connected with puncture drainage tube, the utility model utilizes double shaft air cylinder to drive clamping seat to drag telescopic hose axial elongation, increases the closed volume of drainage pipeline and forms negative pressure buffer cavity, realizes peak shaving and valley filling to the pressure peak and valley of intermittent air extraction of negative pressure equipment, effectively suppresses the violent fluctuation of negative pressure, simultaneously with the help of telescopic hose flexible characteristic attenuation mechanical pulsation shock wave, blocks the transmission of pressure oscillation to patient's abdominal cavity, avoids peritoneal irritation discomfort.

Provided is a method for culturing a sample of cells, which includes circulating epithelial cells, peripheral blood mononuclear cells (PBMC), or body fluid-derived cell samples (e.g. blood, ascites, pleural effusions, cerebrospinal fluids, perfusion fluids, sputum, and urine), or liquid biopsyderived cell samples in presence of Bone Morphogentic Protein (BMP) inhibitor, a mitogenic growth factor, and a Wnt agonist, when culturing the circulating epithelial cells and relevant blood cells. Also provided is use of cell medium having a BMP inhibitor, a mitogenic growth factor, and a Wnt agonist in obtaining a cell culture of circulating epithelial cells, PBMC and body fluid-derived cells.