The invention discloses a halogen-free resin composition and a low-fluidity prepreg thereof. The halogen-free resin composition comprises, by weight, 20-80 parts of an epoxy resin composition, 10-50 parts of phenoxy resin, 10-50 parts of a flame retardant, 3-30 parts of a toughening agent, 10-80 parts of an inorganic filler, 1-10 parts of a curing agent, 0-5 parts of an accelerator and 0-80 partsof an additive. The halogen-free resin composition obtained by modifying common epoxy resin with bisphenol F phenoxy resin, liquid epoxy resin and long chain-containing aliphatic epoxy resin has low viscosity and good wettability, and the low-fluidity prepreg produced from the halogen-free resin composition has the advantages of high flexibility, high Tg and bonding strength, excellent heat resistance, greenness, environmental protection, no resin dust, and realization of long-term preservation.