External preparation of Chinese traditional medicine for improving ascites due to cirrhosis, and preparation method

A technology of liver cirrhosis ascites and external preparations, applied in the field of traditional Chinese medicine preparations

Active Publication Date: 2007-02-21
常熟雷允上制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although traditional Chinese medicine has a long history of applying umbilicus to treat liver cirrhosis ascites, it is widely used and has distinctive characteristics, but there is no new traditional Chinese medicine in the form of external application so far.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment 1 Preparation of Chinese medicine external preparation of the present invention

[0012] 1. Shidiao formula for liver cirrhosis ascites syndrome

[0013] 1. Using the traditional Chinese medicine Radix Astragali, Danfu Tablets, Cinnamon, Rhizoma Cyperi, Clove, Borneolum and Musk to prepare the extract cataplasm for deficiency syndrome. The weight ratio of the pharmaceutically active components is as follows:

[0014] Raw Astragalus 20-500g Danfu Tablets 20-500g

[0015] Cinnamon 20-500g Cyperus 20-500g

[0016] Clove 20-500g Borneol 4-100g Musk 200-500mg (natural or artificial musk)

[0017] The medicinal materials of the above formula totaled 104.2-2600.5g, with an average of 580g, and were made into 20 cataplasms.

[0018] Take a total of 400g of raw astragalus, Danfu tablets, cinnamon, and Cyperus cyperi, add water to decoct twice, the first time 8 times the amount of water, decoct for 2 hours; the second time 6 times the amount of water, decoct for 1 ...

Embodiment 2

[0042] Example 2 The clinical curative effect of catarrh of Shizhang Recipe and Xuzhang Recipe in adjuvant treatment of liver cirrhosis and ascites with excess and deficiency syndromes

[0043] The preparation of the invention has been studied in clinical pharmacodynamics, and the results show that it has a new application of improving liver cirrhosis ascites.

[0044] Diagnostic criteria

[0045] Standards of western medicine: in line with the diagnostic criteria of the 2000 Xi'an National Hepatitis Hepatology Conference [1]: a) decompensated cirrhosis (Child-Pugh grade B / C). b) Signs of abnormal liver function and decompensation, such as serum albumin35μmol / L; or elevated ALT and AST; or thrombin Original activity <60%. The patient develops ascites. c) Imaging diagnosis, B-ultrasound shows that the liver shrinks, the liver surface is obviously uneven, jagged or wavy, the liver edge becomes blunt, the echo of the liver parenchyma is uneven, enhanced, and nodular, and the inn...

Embodiment 3

[0073] Example 3 Example of a typical medical record:

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PUM

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Abstract

An exterior-applied Chinese medicine for treating hepatocirrhosis ascites is prepared from 7 Chinese-medicinal materials including astragalus root (or rhubarb), cloves, borneol, musk, etc. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine preparations. Specifically, it relates to a traditional Chinese medicinal preparation for improving liver cirrhosis ascites and a preparation method thereof. Background technique: [0002] Liver cirrhosis is the end-stage lesion of chronic liver disease, an important disease that causes human death, and seriously endangers human health. There are many causes, including hepatitis virus, schistosomiasis, drugs, alcohol and chemical poisoning. Ascites is the most common complication of liver cirrhosis. In the stage of liver decompensation, ascites is often caused by elevated portal pressure, decreased plasma albumin, infection, and endotoxemia, which seriously affects the health and quality of daily life of patients. . Therefore, it is of great significance to actively prevent and treat ascites and reduce abdominal distension and other symptoms to improve the quality of life of patient...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P1/16A61P7/10A61K35/55
Inventor 刘成海张雅丽冯年平薛惠明蔡俊萍朱华燕史美育
Owner 常熟雷允上制药有限公司
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