The invention discloses a seaborne seasickness prevention sleeping bed. The bed comprises a bed body, a bed board and a bedside back cushion, the bed board is riveted to the upper end face of the bedbody, a mattress is placed on the upper end face of the bed board, an air bag structure is glued to the lower end of the mattress and comprises a left air cavity, a middle cavity and a right air cavity, and a plurality of sets of air nozzles are installed at the bottom of the left air cavity and the bottom of the right air cavity respectively. The air bag structure is designed, power is generatedthrough sliding of a gravity sliding block according to the wobble direction of a vessel to discharge air from an air cylinder and inflate the air bag, the corresponding part of the mattress is raiseddue to bulging of the air bag, and the sense of weightlessness brought by inclination of the bed body to one side can be offset to a certain degree; and the whole sleeping bed is simple in design andconvenient to operate, solves the problems of seasickness and insomnia of a user from the aspects of guaranteeing body balance, shielding external information and guaranteeing oxygen supply, is suitable for different working conditions, and brings a good using prospect.