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184results about How to "Reduce physical and mental damage" patented technology
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Lower cervical spine anterior pedicle screw matching fixing device
InactiveCN104921794AEasy to fixEasy to implantInternal osteosythesisBone platesCervical spineIliac screw
The invention discloses a lower cervical spine anterior pedicle screw matching fixing device which comprises a fixing plate and pedicle screws which are matched. At least two fixing holes matched with the pedicle screws are formed in the fixing plate. The cross section and the longitudinal section of the fixing plate are of an arc structure. The axis of each pedicle screw and the cross section of the fixing plate form a heeling angle of 15-30 degrees. The axis of each pedicle screw and the longitudinal section of the fixing plate form a trimming angle of 0-15 degrees. The pedicle screws are provided with fixing gaskets which are matched respectively. The fixing plate, the pedicle screws and the fixing gaskets are made of biodegradable materials. The implanting operation space of the pedicle screws is increased, and fixing of the fixing plate can be well achieved. When the pedicle screws are implanted completely, the heads of the pedicle screws are placed in the fixing holes. The lower cervical spine anterior pedicle screw matching fixing device is simple in structure and convenient to machine, the cross section and the longitudinal section of the fixing plate are of the arc structure, and accordingly fixing of the fixing plate and a spine body is firm.
Owner:赵刘军
Simple chip device easy to disassemble and assemble and suitable for joint detection of typical tumor markers
PendingCN107199057AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial analysisUltrasonic sensorCapillary channel
The invention relates to a simple chip device easy to disassemble and assemble and suitable for joint detection of typical tumor markers, and belongs to the field of analytical test. PDMS, namely polydimethylsiloxane, has both advantages and serial problems to be solved when used to make a substrate of a microfluidic chip for multichannel joint detection of typical tumor markers; the simple chip device herein is intended to solve the serial problems. The simple chip device is characterized in that PDMS with original ecological surface is selected for a substrate, a hinged clamp with an attached miniature ultrasonic transducer is manually fastened and positioned to a positon close to a sample flow terminal of the microfluidic chip, and an ultrasonic reducer is fitted to a sample injecting end of the microfluidic chip; therefore, ultrasonic strength is gradually decreased fast within a short range, an interfacial tension difference occurs between the two ends of the chip, and a sample flow is driven to flow along an originally hydrophobic capillary passage to the terminal. The simple chip device has no need for a miniature pump.
Owner:葛宇杰
Traditional Chinese medicine composition for diabetic foot
InactiveCN108210693AReduce morbidityReduce physical and mental damageMetabolism disorderDermatological disorderTherapeutic effectDiabetic foot
The invention discloses a traditional Chinese medicine composition for a diabetic foot. The traditional Chinese medicine composition is an external-use dosage form, and the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine components: radix angelicae dahuricae, radix angelicae pubescentis, ramulus cinnamomi, herba ephedrae, radix sophorae flavescentis, cortex phellodendri, rhizoma coptidis, radix scutellariae lateriflorae, airpotato yam rhizome, radix clematidis, common threewingnut roots, rhizoma atractylodis, rhizoma typhonii, rhizoma smilacis glabrae, rhizoma chuanxiong, radix et rhizoma salviae miltiorrhizaef, radix astragali and radix angelicae sinensis. Through in vitro drug administration, in accordance with traditional Chinese medicine theory, circulation is carried out from head to wei chung point, so that a blood circulation condition of a foot part and sensory disturbance of a patient are improved, regeneration of necrotic parts of the foot part can be promoted, and the traditional Chinese medicine composition has a good treatment effect on the diabetic foot.
Owner:吴蓓莉
Conveniently disassembled/assembled concise chip device for combined detection of typical tumor markers
InactiveCN107694647AGood compatibilityRapid reversible binding reactionLaboratory glasswaresMaterial electrochemical variablesShortest distanceCapillary Tubing
The invention relates to a simple disassembled and assembled chip device for combined detection of typical tumor markers, which belongs to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for multi-channel joint detection of typical tumor markers. It has advantages and a series of problems that need to be solved; this case is aimed at this series of problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned in the vicinity of the sample liquid flow terminal of the microfluidic chip, so as to Ultrasound reduces the interfacial tension, which greatly increases the interfacial compatibility between the relevant solid-liquid two phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming an interface at both ends of the chip. The difference in tension thereby facilitates the flow of the sample fluid toward the terminal along the originally hydrophobic capillary channel. The device does not require a micropump.
Owner:洪小女
Dual-drive-coupled chip unit with PDMS as substrate for combined detection of tumor markers
InactiveCN107754941AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial analysisStream flowEngineering
The invention relates to a dual-drive chip device for joint detection of tumor markers with PDMS as a substrate, belonging to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for multi-channel combined detection of typical tumor markers, and there are several problems. The main point of this case is that the PDMS with the original ecological surface is selected as the substrate, and the hinged fixture with the micro-ultrasonic transducer is manually fastened and positioned at the terminal position of the sample liquid flow of the chip, and the interface is formed by ultrasonic induction. The driving force of the tension difference, coupled with the driving force of the micropump, synergistically drives the sample liquid to flow in the direction of the terminal. The pipe of the chip is filled with micron-sized silica particle fillers. The functions of the filler include supporting The inner wall of the pipeline, and a collection of hydrophilic micro-channels are used to compensate the original hydrophobic pipeline, and the inner wall of the pipeline is squeezed and covered to reduce the chance of biomacromolecules in contact with the inner wall.
Owner:蒋剑萍
Chip device for jointly detecting typical tumor markers for physical examination and screening for women
PendingCN107199059AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial electrochemical variablesMicrofluidic chipMicro fluidic
The invention relates to a chip device for jointly detecting typical tumor markers for physical examination and screening for women, and belongs to the field of analysis and tests. Substrates of micro-fluidic chips which are used for jointly detecting eight typical tumor markers and are applicable to women are made of PDMS, namely polydimethylsiloxane, and have merits in the aspects of prices and processes, but difficult shortcomings can be caused. The chip device aims to overcome the difficult shortcomings. The scheme mainly includes that a substrate is made of selected PDMS with original ecological surfaces, a hinge type fixture attached with miniature ultrasonic transducers is manually fastened and positioned at a location adjacent to a sample liquid flow end point of a micro-fluidic chip, and ultrasonic reducers are arranged at a sample injection end of the micro-fluidic chip, so that the ultrasonic intensity can be quickly progressively reduced in short distances, interfacial tension difference can be formed at two ends of the micro-fluidic chip, and sample liquid flow can be promoted to flow towards the direction of the end point along originally hydrophobic capillary channels. The chip device has the advantage that micro-pumps can be completely omitted.
Owner:葛宇杰
Fifteen-channel microfluidic chip apparatus for general investigation of tumor markers
InactiveCN107754886AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial analysisSilica particleTransducer
The invention relates to a fifteen-channel microfluidic chip device for general screening of tumor markers, belonging to the field of analysis and testing. If PDMS, or polydimethylsiloxane, is used to make the substrate of a microfluidic chip for the joint detection of more than ten tumor markers, there are several technical difficulties. The main point of this case is that the substrate is selected from PDMS with an original ecological surface, and the link-type electromagnetic fixture equipped with a micro-ultrasonic transducer is socketed and positioned in the vicinity of the sample liquid flow terminal of the microfluidic chip. Ultrasonic waves are used to induce the sample liquid to flow from the sample injection end of the chip along the pipe of the chip to the terminal. The pipe of the chip is filled with micron-sized silica particle fillers. The function of the filler includes supporting the inner wall of the pipe. , and, use a collection of hydrophilic micro-channels to compensate the original hydrophobic pipeline, and squeeze and cover the inner wall surface of the pipeline so as to reduce the chance of biomacromolecules contacting the inner wall surface.
Owner:李榕萍
Disposable touch-free induction-type vaginal dilator device
PendingCN111419166AReduce physical and mental damageShorten operation timeEndoscopesObstetrical instrumentsVaginal dilatorEngineering
The invention discloses a disposable touch-free induction-type vaginal dilator device and belongs to the technical field of medical instruments. The disposable touch-free induction-type vaginal dilator device comprises a lower expansion piece and an upper expansion piece, wherein the upper expansion piece and the lower expansion piece are connected through rotating shafts on the left side and theright side; the lower expansion piece is connected to a telescopic belt connecting shaft and a traceless connecting pipe; a power mechanism is rotatably connected to the interior of the traceless connecting pipe through the telescopic belt connecting shaft; an inductor is fixedly connected to the tail end of the power mechanism, and the sensor starts an electric motor and starts an elastic telescopic belt to tighten and rotate downwards through gesture induction, so that the expansion angle is controlled; and meanwhile, the start and the stop of the power mechanism can be controlled through the gesture induction. Compared with traditional manual vaginal dilators, the disposable touch-free induction-type vaginal dilator device controls the opening and closing of the expansion pieces throughthe power mechanism, saves time and labor, and can greatly reduce the operation time and reduce the physical and mental injury to a patient.
Owner:WUXI HAIYING ELECTRONICS MEDICAL SYST
Crew seasickness resistance training apparatus
InactiveCN106781963AReduce physical and mental damageImprove securityEducational modelsSimulationResistance training
A crew seasickness resistance training apparatus comprises a heaving motion unit, a pitching motion unit, a rolling motion unit and a fixed pedestal. The heaving motion unit is installed on the pitching motion unit. The pitching motion unit is placed on the rolling motion unit. The rolling motion unit is placed on the fixed pedestal. The fixed pedestal is placed on the ground. The crew seasickness resistance training apparatus of the invention can highly simulate a complex motion form of a ship in a sea environment so that a vivid training platform is provided for crew seasickness resistance capability training.
Owner:CHINA SHIP DEV & DESIGN CENT
Six-channel micro-fluidic chip device for combined detection of abridged tumor markers
InactiveCN106814184AGood compatibilityRapid reversible binding reactionBiological testingMaterial electrochemical variablesAbnormal tissue growthShortest distance
The invention relates to a six-channel micro-fluidic chip device for combined detection of abridged tumor markers, belonging to the field of analytical testing. The micro-fluidic chip device used for producing a substrate of the micro-fluidic chip for combined detection of classic tumor markers prepared from PDMS (polydimethylsiloxane) has advantages and a series of difficulties; and the invention aims at solving the series of difficulties. The invention is mainly characterized in that PDMS with originally ecological surface is selected as the substrate, a chain ring type electromagnetic clamp with a minitype ultrasonic energy transducer is sheathed at and positioned at a position close to the liquid flow end of a test sample of the micro-fluidic chip, the interfacial tension is reduced ultrasonically, so that the interfacial compatibility between the solid and liquid phases is greatly increased, the ultrasonic intensity is rapidly decreased progressively within short distance by utilizing the strong absorption capability of PDMS to ultrasonic wave, so that the interfacial tension difference is formed at the two ends of the chip, therefore, the liquid flow of the test sample is driven to flow to the end along the direction of originally hydrophobic capillary channel. The device does not use a micropump.
Owner:NINGBO UNIV
Dual-drive tumor marker joint inspection chip device with PDMS as substrate
InactiveCN106610429AEasy to processEasy to disassembleMaterial analysisUltrasonic sensorShortest distance
The invention relates to a dual-drive tumor marker joint inspection chip device with PDMS as a substrate and belongs to the field of analysis test. Utilizing polydimethyl siloxane, namely PDMS, to prepare the substrate of a typical tumor marker multichannel joint inspection micro-fluidic chip has advantages and also has problems; aiming at the problems, the dual-drive tumor marker joint inspection chip device is characterized in that the substrate is chosen from the PDMS with the original surface, a hinge type clamp additionally provided with a minitype ultrasonic transducer is manually fastened and located to the neighbor position of a sample fluid terminal of the micro-fluidic chip, the interfacial tension is reduced by ultrasonic wave, and the rapid decreasing of the ultrasonic wave strength in a short distance is achieved through the strong absorption ability of the PDMS to the ultrasonic wave; thus the interfacial tension difference is formed between the two ends of the chip, the difference can provide the force for driving the sample fluid to flow in the direction from a drainage capillary channel to the terminal, and the force is also coupled with and in collaborative operation with the mechanical pumping force of a micro pump contained in the structure of dual-drive tumor marker joint inspection chip device.
Owner:NINGBO UNIV
Microfluidic chip apparatus for multi-channel simultaneous detection of six typical tumor markers
InactiveCN107486268AKeep time shortLong-lasting superhydrophilic propertiesLaboratory glasswaresMaterial electrochemical variablesAbnormal tissue growthMicron scale
The present invention relates to a microfluidic chip apparatus for multi-channel simultaneous detection of six typical tumor markers, and belongs to the field of analytical testing. According to the present invention, the use of inexpensive and easily-processed polydimethylsiloxane (PDMS) to produce the substrate of a microfluidic chip for multi-channel simultaneous detection of six typical tumor markers has a series of problems that the surface of the PDMS is strongly hydrophobic and the surface chemical modification effect is difficult to last. The technical scheme of the present invention is that the substrate material is PDMS with an original ecological surface, the pipeline of the chip is filled with doped micron-scale titanium dioxide particles, the surface super-hydrophilicity of the titanium dioxide particles can be induced by visible light irradiation in advance, and the set of the titanium dioxide particle filler and the super-hydrophilic gap between the particles can compensate and beyond the original strong hydrophobic pipeline, such that the constant and super hydrophilic modification effect is achieved. In addition, the titanium dioxide filler can further be used for preventing the pipeline of the chip from collapsing and deforming, and blocking biological macromolecules from contacting the inner wall of the pipeline.
Owner:李榕生
Micro-fluidic chip device for combined detection of multiple female classic tumor markers
InactiveCN106807457AGood compatibilityRapid reversible binding reactionLaboratory glasswaresShortest distanceCapillary channel
The invention relates to a micro-fluidic chip device for combined detection of multiple female classic tumor markers, belonging to the field of analytical testing. The micro-fluidic chip device used for producing a substrate of the micro-fluidic chip for combined detection of eight female classic tumor markers through PDMS (polydimethylsiloxane) has both price and technology advantages and difficulties. The invention aims at solving the difficulties. The invention has the characteristics that PDMS with originally ecological surface is selected as the substrate, a chain ring type electromagnetic clamp with a minitype ultrasonic energy transducer is sheathed at and positioned at a position close to the liquid flow end of a test sample of the micro-fluidic chip, the interfacial tension is reduced ultrasonically, so that the interfacial compatibility between the solid and liquid phases is greatly increased, the ultrasonic intensity is rapidly decreased progressively within short distance by utilizing the strong absorption capability of PDMS to ultrasonic wave, so that the interfacial tension difference is formed at the two ends of the chip, therefore, the liquid flow of the test sample is driven to flow to the end along the direction of originally hydrophobic capillary channel. The device does not use a micropump.
Owner:NINGBO UNIV
Easily-disassembled chip device for combined detection of typical tumor markers of male
InactiveCN107694632AGood compatibilityRapid reversible binding reactionLaboratory glasswaresMaterial electrochemical variablesAbnormal tissue growthShortest distance
The invention relates to an easily disassembled chip device for joint detection of typical male tumor markers, which belongs to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for the joint detection of seven typical tumor markers in men. It has many advantages, but there are also a series of problems; this case is aimed at this series of problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned at the position adjacent to the sample liquid flow terminal of the microfluidic chip, so as to Ultrasound reduces the interfacial tension and greatly increases the interfacial compatibility between solid and liquid phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming a difference in interfacial tension at both ends of the chip. , thereby promoting the flow of the sample liquid to flow toward the terminal along the originally hydrophobic capillary channel. The device does not require the use of micropumps.
Owner:洪小女
Microfluidic chip apparatus suitable for females and used for combined detection of typical tumor markers
InactiveCN107486269AKeep time shortLong-lasting superhydrophilic propertiesLaboratory glasswaresMaterial analysisMicron scaleEngineering
The present invention relates to a microfluidic chip apparatus suitable for females and used for combined detection of typical tumor markers, and belongs to the field of analytical testing. According to the present invention, the use of PDMS to produce the substrate of a microfluidic chip suitable for females and used for combined detection of typical tumor markers has a series of problems that the surface of the PDMS is strongly hydrophobic and the surface chemical modification effect is difficult to last. The technical scheme of the present invention is that the substrate material is PDMS with an original ecological surface, the pipeline of the chip is filled with doped micron-scale titanium dioxide particles, the surface super-hydrophilicity of the titanium dioxide particles can be induced by visible light irradiation in advance, and the set of the titanium dioxide particle filler and the super-hydrophilic gap between the particles can compensate and beyond the original strong hydrophobic pipeline, such that the constant and super hydrophilic modification effect is achieved. In addition, the titanium dioxide filler can further be used for preventing the pipeline of the chip from collapsing and deforming, and blocking biological macromolecules from contacting the inner wall of the pipeline.
Owner:李榕生
Chip device for female tumor marker joint inspection in multi-driving mode coupling operation
PendingCN107282145AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial analysisMicrofluidic chipMicro fluidic
The invention relates to a chip device for female tumor marker joint inspection in multi-driving mode coupling operation, and belongs to the field of analysis and test. If PDMS (polydimethylsiloxane) is used for manufacturing a substrate of a female applicable micro-fluidic chip for typical tumor marker joint inspection, the advantages in the price and process are realized, but the difficult problems also exist. The scheme aims at the difficult problems and is characterized in that the substrate selects the PDMS with the original ecology surface; a miniature ultrasonic transducer is fixedly arranged in an adjacent position of the specimen liquid flow terminal of the micro-fluidic chip; meanwhile, the sampling end of the micro-fluidic chip is provided with an ultrasonic attenuator; the effect that the ultrasonic intensity is fast decreased progressively in short distance is achieved, so that the interfacial tension difference is formed at two ends of the chip; the difference provides force for driving specimen liquid flow to flow along a hydrophobic capillary channel towards the terminal direction; the power is mutually coupled and collaboratively operated with micropump mechanical pumping power contained in the structure at the same time.
Owner:葛宇杰
Coal gangue grading recycling device
InactiveCN111375455ARealize multi-stage screeningImprove utilization efficiencyDirt cleaningGrain treatmentsElectric machineryProcess engineering
The invention discloses a coal gangue grading recycling device, and relates to the technical field of coal screening equipment. A fixed plate is perpendicularly and fixedly arranged on the right sideof the inner top of a box, a gap is arranged between the fixed plate and the right side wall of the box, a sliding rail is fixedly arranged on the inner top of the box, a sliding block is slidably arranged on the sliding rail, a connecting column is perpendicularly and fixedly arranged at the bottom of the sliding block, a screening mechanism is fixedly arranged at the bottom of the connecting column, a screw rod is fixedly arranged at the output end of a first motor and rotatably arranged in the middle of the connecting column through a thread in a penetrating mode, first and second discharging openings are sequentially formed in the left side wall of the box from top to bottom, a chute is fixedly arranged on the inner side wall of the box at the bottom of the second discharging opening,and the right side of the chute is arranged under the screening mechanism. According to the coal gangue grading recycling device, multi-grade screening can be conducted on crushed coal gangue, the utilization efficiency of the coal gangue can be improved, the pollution of an operating environment is prevented, the physical and mental injury to a worker is reduced, and meanwhile, the waste of materials can be reduced.
Owner:宁夏劲远达新材料科技有限公司
15-channel micro-fluidic chip device for common tumor marker screening
InactiveCN107282151AEasy to disassembleEasy to disengageLaboratory glasswaresMaterial electrochemical variablesAbnormal tissue growthUltrasonic sensor
The invention relates to a fifteen-channel microfluidic chip device for screening common tumor markers, belonging to the field of analysis and testing. If PDMS, polydimethylsiloxane, is used to make the substrate of a microfluidic chip for the joint detection of more than ten kinds of tumor markers, it has both advantages and difficulties; this case aims at this problem. The main point of this case is that the PDMS with the original ecological surface is selected as the substrate, and the elastic clamp with the micro-ultrasonic transducer attached to the clamping arm is elastically positioned on the sample liquid flow terminal of the microfluidic chip and its neighbors. At the same time, an ultrasonic reducer is installed at the sampling end of the microfluidic chip to achieve a rapid decrease in the ultrasonic intensity in a short distance, thereby forming a difference in interfacial tension at both ends of the chip, which provides a way to drive the sample The force of the liquid flow along the hydrophobic capillary channel towards the terminal, and at the same time cooperates with the mechanical pumping force of the micropump contained in the structure.
Owner:李榕生
Mechanical Mechanism and Working Method of Pipe Grinding Robot
ActiveCN111469000BEasy to installImprove securityGrinding carriagesRevolution surface grinding machinesElectric machineryEngineering
The invention discloses a mechanical structure of a pipeline grinding robot, which is used for grinding pipelines. The mechanical structure includes frame parts, pipe clamping device, motion system, and grinding assembly; the motion system drives the grinding assembly to move freely along three dimensions, namely, moving back and forth along the axis of the pipeline, moving circularly around the axis of the pipeline to be polished, and moving toward the The grinding pipeline moves back and forth in the radial direction, and the high-speed rotating motor assembled on the grinding assembly drives the grinding wheel, which can fully polish the area to be polished of the pipeline to be polished. The invention also discloses the working method of the mechanical structure. The motion system can move freely in three dimensions along the pipeline axis direction, the circumferential direction of the pipeline to be polished, and the radial direction of the pipeline to be polished. The grinding component is installed on the motion system, driven by the motion system Next, the grinding assembly can move freely along the above three dimensions, and the area to be polished of the pipeline to be polished is polished under the action of the high-speed rotating grinding wheel on the grinding assembly. Three-dimensional grinding, good flexibility and high grinding precision.
Owner:ZHONGBEI UNIV
Tumor marker combined detection chip device suitable for female physical examination screening
InactiveCN107126983AReduce demandReduce physical and mental damageLaboratory glasswaresBiological testingUltrasonic sensorAbsorption capacity
The invention relates to a tumor marker combined detection chip device suitable for female physical examination screening, and belongs to the field of analysis and testing. If PDMS (polydimethylsiloxane) is used for manufacturing a substrate of a micro-fluidic chip for combined detection of eight typical tumor marker applicable to females, advantages and problems exist, and the device is used for solving the problems. The device is mainly characterized in that the substrate is prepared from the selected PDMS with an original ecological surface, a chain-ring electromagnetic fixture provided with a miniature ultrasonic transducer is positioned near a sample liquid flow terminal of the micro-fluidic chip in a sleeve connection manner, interfacial tension is reduced by ultrasonic waves, ultrasonic intensity is rapidly decreased progressively in a short distance by the aid of strong absorption capacity of the PDMS for the ultrasonic waves, interfacial tension difference is formed at two ends of the chip and provides force for driving sample liquid flow to flow towards the terminal along a hydrophobic capillary channel, and the force is coupled and cooperated with the mechanical pumping force of a micro-pump in the structure.
Owner:NINGBO UNIV
Microfluidic chip device for multi-channel simultaneous detection of six typical tumor markers
InactiveCN107225005AGood compatibilityEliminate adsorptionLaboratory glasswaresMaterial analysisAbnormal tissue growthUltrasonic sensor
The invention relates to a microfluidic chip device for multi-channel simultaneous detection of six typical tumor markers, and belongs to the field of analysis and testing. Polydimethylsiloxane, i.e. PDMS, is used for preparing a substrate of the microfluidic chip for multi-channel combined detection of six typical tumor markers, which has obvious advantages but also has a series of challenges. Aiming at the series of challenges, the invention is provided. The key points of the invention are as follows: the PDMS with an original form surface is selected as the substrate; a micro ultrasonic transducer is attached to a position adjacent to a sample liquid flow terminal of the microfluidic chip; and meanwhile, the sample injection end of the microfluidic chip is provided with an ultrasonic attenuator, so that the ultrasonic strength quickly descends within a short distance, an interfacial tension difference is thus formed between the two ends of the chip, the interfacial tension difference causes a pressure difference between the two ends, and the pressure difference drives a liquid flow to flow towards the terminal along an original high-hydrophobicity pipeline.
Owner:葛宇杰
Micro-fluidic chip device for simultaneously detecting women's various typical tumor markers
InactiveCN106568952AReduce demandReduce physical and mental damageMaterial analysisAbnormal tissue growthUltrasonic sensor
The invention relates to a micro-fluidic chip device for simultaneously detecting women's various typical tumor markers and belongs to the field of analytical test. PDMS, namely polydimethylsiloxane, is used for preparation of a substrate of a micro-fluidic chip suitable for combined detection of women's eight typical tumor markers. There are advantages in price and process, but difficulties also exist. The invention aims to overcome the difficulties. Main points of the scheme are as follows: the PDMS with an original ecological surface is selected as the substrate, and an elastic clamp with a miniature ultrasonic transducer attached to the clamping arm is, by elastic clenching, positioned at the neighboring position of a sample fluid terminal of the micro-fluidic chip, so as to reduce interfacial tension and increase interfacial compatibility by means of ultrasonic wave; meanwhile, by strong ultrasonic wave absorption power of PDMS, ultrasonic intensity is rapidly decreased progressively within a short distance such that an interfacial tension difference is formed across the two ends of the chip and thereby the sample fluid flows towards the direction of the terminal along the original hydrophobous capillary channel. The device is completely used without a micropump.
Owner:NINGBO UNIV
Micro fluidic chip device for combined detection of multiple typical tumor marker of female
InactiveCN107694637AGood compatibilityRapid reversible binding reactionLaboratory glasswaresMaterial analysisAbnormal tissue growthShortest distance
The invention relates to a microfluidic chip device for combined detection of various typical female tumor markers, which belongs to the field of analysis and testing. Using PDMS or polydimethylsiloxane to make the substrate of the microfluidic chip for the combined detection of eight typical tumor markers suitable for women has advantages in price and technology, but there are also difficulties; this case aims to overcome this difficulty . The main point of this case is that the substrate is selected from PDMS with an original ecological surface, and the link-type electromagnetic fixture equipped with a micro-ultrasonic transducer is socketed and positioned in the vicinity of the sample liquid flow terminal of the microfluidic chip. Ultrasound is used to reduce the interfacial tension, which greatly increases the interfacial compatibility between the solid and liquid phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming an interface at both ends of the chip. The difference in tension thereby facilitates the flow of the sample fluid toward the terminal along the originally hydrophobic capillary channel. The device eliminates the need for a micropump.
Owner:宋岳
Microfluidic chip device used for fifteen-channel combined detection on plurality of tumor makers
InactiveCN107213926AGood compatibilityRapid reversible binding reactionLaboratory glasswaresMaterial electrochemical variablesMicrofluidic chipTumor marker
The invention relates to a microfluidic chip device used for fifteen-channel combined detection on a plurality of tumor makers, and belongs to the field of analysis and testing. Advantages are obvious if PDMS, which is polydimethylsiloxane, is adopted to prepare a substrate of a universal-type microfluidic chip device used for combined detection on more than ten tumor makers, whereas, a plurality of problems which need to be overcome exist, and the invention aims to solve the problems. The key points of the invention comprise PDMS which has an original ecology surface is selected as a substrate, and an elastic clamp which is equipped with a micro ultrasonic wave transducer on a clamping arm is located at a neighbouring position of a sample liquid terminal of a microfluidic chip by elastic occlusion, and in addition, an ultrasonic wave attenuator is arranged on a sample introduction terminal of the microfluidic chip, so as to achieve a rapid decrease of ultrasonic wave intensity in a short distance, so that interfacial tension difference is formed at two ends of the chip, and accordingly, a sample liquid is forced to flow along an originally hydrophobic capillary tube channel to the terminal direction. The device can work without using a micropump.
Owner:李榕生
Universal chip device easy to disassemble and suitable for joint detection of various tumor markers
PendingCN107199058AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial electrochemical variablesMicrofluidic chipBiomedical engineering
The invention relates to a universal chip device easy to disassemble and suitable for joint detection of various tumor markers, and belongs to the field of analytical test. PDMS, namely polydimethylsiloxane, has both significant advantages and multiple problems to be solved when used to make a substrate of a universal microfluidic chip for joint detection of more than ten tumor markers; the universal chip device is intended to solve the problems. The universal chip device is characterized in that PDMS with original ecological surface is selected for a substrate, a hinged clamp with an attached miniature ultrasonic transducer is manually fastened and positioned to a position close to a sample flow terminal of the microfluidic chip, an ultrasonic reducer is fitted to a sample injection end of the microfluidic chip, and accordingly ultrasonic strength can be gradually decreased quickly within a short range; therefore, an interfacial tension difference occurs between two ends of the chip, and a sample flow is driven to flow to the terminal along an originally hydrophobic capillary passage.
Owner:葛宇杰
Microfluidic chip device for combined detection of typical tumor markers for female
InactiveCN107225002AGood compatibilityEliminate adsorptionLaboratory glasswaresMaterial electrochemical variablesAbnormal tissue growthUltrasonic sensor
The invention relates to a microfluidic chip device for combined detection of typical tumor markers for a female, and belongs to the field of analysis and testing. PDMS, i.e. polydimethylsiloxane, is used for preparing a substrate of the microfluidic chip for combined detection of typical tumor markers for a female, which has price and process advantages but also has challenges. Aiming at the challenges, the invention is provided. The key points of the invention are as follows: the PDMS with an original form surface is selected as the substrate; a micro ultrasonic transducer is attached to a position adjacent to a sample liquid flow terminal of the microfluidic chip; and meanwhile, the sample injection end of the microfluidic chip is provided with an ultrasonic attenuator, so that the ultrasonic strength quickly descends within a short distance, an interfacial tension difference is thus formed between the two ends of the chip, the interfacial tension difference causes a pressure difference between the two ends, and the pressure difference drives a sample liquid flow to flow towards the terminal along an original high-hydrophobicity capillary level channel.
Owner:葛宇杰
Microfluidic chip device for combined detection of typical tumor markers of male
InactiveCN107213925AGood compatibilityRapid reversible binding reactionMaterial analysis by electric/magnetic meansLaboratory glasswaresAbnormal tissue growthUltrasonic sensor
The invention relates to a microfluidic chip device for combined detection of typical tumor markers of a male, and belongs to the field of analysis and testing. Polydimethylsiloxane, i.e. PDMS, is used as a substrate for preparing the microfluidic chip for combined detection of seven typical tumor markers of a male, which has a plurality of advantages but also has a series of challenges. Aiming at the series of challenges, the invention is provided. The key points of the invention are as follows: the PDMS with an original form surface is selected as the substrate; an elastic clamp is elastically clamped and located in a position adjacent to a sample liquid flow terminal of the microfluidic chip, wherein a micro ultrasonic transducer is attached to clamping arms of the elastic clamp; and meanwhile, the sample injection end of the microfluidic chip is provided with an ultrasonic attenuator, so that the ultrasonic strength quickly descends within a short distance, and an interfacial tension difference is formed between both ends of the chip, thereby urging a sample liquid flow to flow towards the terminal along an original hydrophobic capillary channel. Besides, the device avoids the use of a micropump.
Owner:李榕生
Iron wire fixing plier for reinforcing steel and using method of iron wire fixing plier
PendingCN110593577AQuick wrap bundleReduce labor intensityBuilding material handlingEngineeringRebar
Owner:浙江中正岩土技术有限公司
Easily-disassembled chip device for joint inspection of male typical tumor markers
InactiveCN107436353AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial analysisSilica particleAbnormal tissue growth
The invention relates to an easily disassembled chip device for joint detection of typical male tumor markers, which belongs to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for the joint detection of seven typical tumor markers in men, and there are a series of problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned at the position adjacent to the sample liquid flow terminal of the microfluidic chip, so as to The ultrasonic wave induces the sample liquid flow to flow from the sample injection end of the chip along the pipe of the chip to the terminal. The pipe of the chip is filled with micron-sized silicon dioxide particle fillers. The function of the filler includes supporting the inner wall of the pipe, And, a collection of hydrophilic micro-channels is used to compensate the originally hydrophobic channels, and the inner wall of the channel is squeezed and covered to reduce the chance of biomacromolecules in contact with the inner wall.
Owner:李榕生
Chip device with multiple coupled drive modes and for combined detection of tumor markers of female
InactiveCN107694629AReduce demandReduce physical and mental damageLaboratory glasswaresMaterial analysisUltrasonic sensorStream flow
The invention relates to a chip device for joint inspection of female tumor markers with multi-drive mode coupling operation, belonging to the field of analysis and testing. The use of PDMS (polydimethylsiloxane) to make the substrate of a microfluidic chip for the combined detection of typical tumor markers for women has advantages in price and technology, but also has difficulties; this case aims to overcome this difficulty. The main point of this case is that the substrate selects PDMS with an original surface, and a micro ultrasonic transducer is fixedly installed in the vicinity of the sample liquid flow terminal of the microfluidic chip to reduce the interfacial tension with ultrasonic waves. The strong absorption capacity of ultrasonic waves makes it possible to rapidly decrease the ultrasonic intensity in a short distance, thereby forming a difference in interfacial tension between the two ends of the chip. This force is also coupled to and works in concert with the mechanical pumping force of the micropump contained in the structure.
Owner:李榕萍
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