48results about How to "Objective reality" patented technology

The invention relates to a cholera diagnosis microfluidic device with a chip using a strong hydrophobic substrate and belongs to the field of analysis and testing. At present, there are practical problems in preparation of a microfluidic chip substrate for diagnosing cholera from cheap and easily processed polydimethylsiloxane PDMS. The PDMS has the strongly hydrophobic surface and the specifically improved or modified surface has no lasting effect. The hydrophobic substrate-containing multi-channel microfluidic chip device solves the above problem. PDMS with the original ecological surface is selected as a substrate, a hinge fixture with a micro-ultrasonic transducer is manually fastened to a position close to a test sample liquid flow terminal of the microfluidic chip, a sample feeding end of the microfluidic chip is provided with an ultrasonic attenuator for fast degression of ultrasonic intensity in a short distance so that two ends of the chip form interfacial tension difference and the sample liquid flows to the terminal along a hydrophobic capillary channel direction.

The invention relates to a subtype swine influenza detection device with an easy-to-remove liquid driving component, and belongs to the field of analytical testing. The subtype swine influenza detection device aims to solve related problems that various obstacles exist when cheap and easy-to-process polydimethylsiloxane (PDMS) is utilized to prepare a substrate of a micro-fluidic chip for subtype swine influenza diagnosis, and the effect of targeted surface modification or surface finish is difficult to last due to strong hydrophobicity of the surface of a PDMS material. The subtype swine influenza detection device is characterized in that the substrate adopts the PDMS with an original surface, an elastic clamp with clamping arms equipped with attached miniature ultrasonic transducers is elastically snapped and located in the position adjacent to a sample liquid flow terminal of the micro-fluidic chip, an ultrasonic attenuator is installed in the sample feeding end of the micro-fluidic chip to achieve rapid ultrasonic intensity decrease in a short distance, so that interfacial tension difference is formed at two ends of the chip, and the sample liquid flow is enabled to flow in a direction of the terminal along a capillary channel.

The invention relates to a cholera diagnosis microfluidic device with a fast-to-remove liquid flow driving accessory, and belongs to the field of analytical testing. The cholera diagnosis microfluidic device with the fast-to-remove liquid flow driving accessory aims to solve related problems that a series of difficulties actually exist when cheap and easy-to-process polydimethylsiloxane (PDMS) is utilized to prepare a substrate of a micro-fluidic chip for cholera diagnosis, and the effect of targeted surface modification or surface finish is difficult to last due to strong hydrophobicity of the surface of a PDMS material. Main points of the cholera diagnosis microfluidic device with the fast-to-remove liquid flow driving accessory are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along a capillary channel to the direction of the terminal.

The invention relates to an AIDS diagnosis device with an easy-to-remove liquid flow driving component, and belongs to the field of analytical testing. A technical obstacle exists in the manufacture of a substrate of an AIDS-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the AIDS diagnosis device with the easy-to-remove liquid flow driving component aims to solve the series of relevant problems. Main points of the AIDS diagnosis device with the easy-to-remove liquid flow driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to a syphilis diagnosis microfluidic device with an easy-to-remove additional liquid flow driving component, and belongs to the field of analytical testing. A technical target is manufacture of a substrate of a syphilis-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the syphilis diagnosis microfluidic device with the easy-to-remove additional liquid flow driving component aims to solve the series of relevant problems. Main points of the syphilis diagnosis microfluidic device with the easy-to-remove additional liquid flow driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to a syphilis diagnosis device with an easy-to-remove additional sample driving component, and belongs to the field of analytical testing. A series of problems exist in manufacture of a substrate of a syphilis-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the syphilis diagnosis device with the easy-to-remove additional sample driving component aims to solve the series of relevant problems. Main points of the syphilis diagnosis device with the easy-to-remove additional sample driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to a simple disassembled and assembled chip device for combined detection of typical tumor markers, which belongs to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for multi-channel joint detection of typical tumor markers. It has advantages and a series of problems that need to be solved; this case is aimed at this series of problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned in the vicinity of the sample liquid flow terminal of the microfluidic chip, so as to Ultrasound reduces the interfacial tension, which greatly increases the interfacial compatibility between the relevant solid-liquid two phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming an interface at both ends of the chip. The difference in tension thereby facilitates the flow of the sample fluid toward the terminal along the originally hydrophobic capillary channel. The device does not require a micropump.

The invention relates to an acquired immunodeficiency syndrome diagnosis apparatus adopting a hydrophobic material as the substrate of a microfluidic chip, and belongs to the field of analysis testing. According to the present invention, the use of inexpensive and easily-processed polydimethylsiloxane (PDMS) to produce the substrate of a microfluidic chip for diagnosing acquired immunodeficiency syndrome is a technical target, but the surface of the PDMS material is strongly hydrophobic and the effect of the targeted surface modification or surface modifying is difficult to lasting, and a purpose of the present invention is to solve the series of the related problems; and the apparatus is characterized in that the substrate selects the PDMS having an original ecological surface, a hinge type fixture provided with a miniature ultrasonic wave transducer is manually fastened and positioned at a position close to the sample liquid fluid terminal end of the microfluidic chip so as to reduce the interfacial tension through the ultrasonic wave, and the strong absorption capacity of the PDMS on the ultrasonic wave is used to rapidly decrease the intensity of the ultrasonic wave within a short distance, such that the interfacial tension difference is formed on both ends of the chip so as to promote the sample liquid fluid to flow to the terminal direction along the originally-hydrophobic capillary channel.

The invention relates to an easily disassembled chip device for joint detection of typical male tumor markers, which belongs to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for the joint detection of seven typical tumor markers in men. It has many advantages, but there are also a series of problems; this case is aimed at this series of problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned at the position adjacent to the sample liquid flow terminal of the microfluidic chip, so as to Ultrasound reduces the interfacial tension and greatly increases the interfacial compatibility between solid and liquid phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming a difference in interfacial tension at both ends of the chip. , thereby promoting the flow of the sample liquid to flow toward the terminal along the originally hydrophobic capillary channel. The device does not require the use of micropumps.

The invention relates to a syphilis diagnosis micro-fluidic apparatus with a liquid flow driving additional member being easy to detach and belongs to the field of analysis and test. In the prior art, a process of producing a substrate of a syphilis diagnosis micro-fluidic chip with polydimethylsiloxane (PDMS), which is low in cost and is easy to process, becomes a technical target. The PDMS has an intensive hydrophobic surface, and effects of specific surface modification and the like cannot be maintained durably, so that the invention aims to solve the related problems. In the embodiment, PDMS having an original ecological surface is employed as the substrate, wherein an elastic clamp, of which a clamping arm is equipped with a micro-ultrasonic transducer, clamps and is located on a position nearby a terminal of a test sample fluid in the micro-fluidic chip through elasticity, so that ultrasonic wave reduces interface tension; and meanwhile, with the strong absorption capability of the PDMS to the ultrasonic wave, quick attenuation of intensity of the ultrasonic wave in a short distance is achieved, thus forming difference between the interface tensions at the two ends of the chip, so that the test sample fluid flows to the direction of the terminal along a capillary path which is originally hydrophobic.

The invention relates to a syphilis diagnosis apparatus used for sample driving and capable of rapidly removing an attached member, belonging to the field of analysis and testing. A substrate used for preparation of syphilis diagnosis micro-fluidic chips and prepared from cheap and easily workable polydimethylsiloxane, i.e., PDMS, have the problems that the PDMS material has a strongly hydrophobic surface; and the effect of directed surface modification cannot last for a long time. The objective of the invention is to overcome the problems. According to main points of a technical scheme in the invention, PDMS with an original surface is selected as a substrate; an elastic clamp, additionally provided with a minisized ultrasonic transducer, of a clamping arm of the substrate is positioned at a position close to a sample liquid flow terminal of a micro-fluidic chip in the manner of elastic occlusion, and ultrasonic waves are used for reducing interfacial tension; meanwhile, in virtue of strong ultrasonic wave absorption capacity of PDMS, rapid and progressive decrease of ultrasonic intensity is realized in a short distance; thus, difference of interfacial tension at two ends of the chip is formed, and sample liquid flow is allowed to flow towards the terminal along an originally-hydrophobic capillary channel.

The invention relates to a cholera diagnosis multi-channel chip device utilizing a PDMS substrate and belongs to the field of analysis and testing. At present, there are practical problems in preparation of a microfluidic chip substrate for diagnosing cholera from cheap and easily processed polydimethylsiloxane PDMS. The PDMS has the strongly hydrophobic surface and the specifically improved or modified surface has no lasting effect. The hydrophobic substrate-containing multi-channel microfluidic chip device solves the above problem. PDMS with the original ecological surface is selected as a substrate, a hinge fixture with a micro-ultrasonic transducer is manually fastened to a position close to a test sample liquid flow terminal of the microfluidic chip, a sample feeding end of the microfluidic chip is provided with an ultrasonic attenuator for fast degression of ultrasonic intensity in a short distance so that two ends of the chip form interfacial tension difference and the sample liquid flows to the terminal along a hydrophobic capillary channel direction.

The invention relates to a multichannel chip device with PDMS as a substrate material and for cholera diagnosis and belongs to the field of analysis and testing. By using cheap and easily-processablepolydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for cholera diagnosis, a series of problems actually exist. The surface of the PDMS material is strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points, PDMS with primitive surface is selected as the substrate, a hinge-type fixture attached with a miniature ultrasonic transducer is manually fastened and positioned near the terminal of a sample liquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension difference between two ends of the chip. Thereby, the sample liquid fluid flows along an originally hydrophobic capillary channel towards the terminal.

The invention relates to a multichannel device with a highly hydrophobic substrate of a microfluidic chip and for syphilis diagnosis and belongs to the field of analysis and testing. It is a technicalobjective to use cheap and easily-processable polydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for syphilis diagnosis. However, the surface of the material is highly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, a hinge-type fixture attached with a miniature ultrasonic transducer is manually fastened and positioned near the terminal of a sample liquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance so as to form interfacial tension difference between two ends of the chip. Thereby, the sample liquid fluid is driven to flow along an originally hydrophobic capillary channel towards the terminal.

The invention relates to a microfluidic chip device used for fifteen-channel combined detection on a plurality of tumor makers, and belongs to the field of analysis and testing. Advantages are obvious if PDMS, which is polydimethylsiloxane, is adopted to prepare a substrate of a universal-type microfluidic chip device used for combined detection on more than ten tumor makers, whereas, a plurality of problems which need to be overcome exist, and the invention aims to solve the problems. The key points of the invention comprise PDMS which has an original ecology surface is selected as a substrate, and an elastic clamp which is equipped with a micro ultrasonic wave transducer on a clamping arm is located at a neighbouring position of a sample liquid terminal of a microfluidic chip by elastic occlusion, and in addition, an ultrasonic wave attenuator is arranged on a sample introduction terminal of the microfluidic chip, so as to achieve a rapid decrease of ultrasonic wave intensity in a short distance, so that interfacial tension difference is formed at two ends of the chip, and accordingly, a sample liquid is forced to flow along an originally hydrophobic capillary tube channel to the terminal direction. The device can work without using a micropump.

The invention relates to a microfluidic chip device for combined detection of typical tumor markers of a male, and belongs to the field of analysis and testing. Polydimethylsiloxane, i.e. PDMS, is used as a substrate for preparing the microfluidic chip for combined detection of seven typical tumor markers of a male, which has a plurality of advantages but also has a series of challenges. Aiming at the series of challenges, the invention is provided. The key points of the invention are as follows: the PDMS with an original form surface is selected as the substrate; an elastic clamp is elastically clamped and located in a position adjacent to a sample liquid flow terminal of the microfluidic chip, wherein a micro ultrasonic transducer is attached to clamping arms of the elastic clamp; and meanwhile, the sample injection end of the microfluidic chip is provided with an ultrasonic attenuator, so that the ultrasonic strength quickly descends within a short distance, and an interfacial tension difference is formed between both ends of the chip, thereby urging a sample liquid flow to flow towards the terminal along an original hydrophobic capillary channel. Besides, the device avoids the use of a micropump.

The invention relates to a sample-driving syphilis diagnosis device with rapidly-removable accessories and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for syphilis diagnosis, some problems exist. The surface of the PDMS material is strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, an elastic clamp with a miniature ultrasonic transducer attached to a clamping arm is in elastic snap-fit to be positioned near the terminal of a sample liquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension difference between two ends of the chip. Thereby, the sample liquid fluid is driven to flow along an originally hydrophobic capillary channel towards the terminal.

The invention relates to an AIDS diagnosis device for liquid flow drive and with easily-removable components and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for AIDS diagnosis, there are technical obstacles. The surface of the material is strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, an elastic clamp with a miniature ultrasonic transducer attached to a clamping arm is in elastic snap-fit to be positioned near the terminal of a sample liquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacialtension difference between two ends of the chip. Thereby, the sample liquid fluid is driven to flow along an originally hydrophobic channel towards the terminal.

The invention relates to a hydrophobic-substrate-containing AIDS-diagnosis multichannel microfluidic chip device, and belongs to the field of analytical testing. A technical obstacle exists in the manufacture of a substrate of an AIDS-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane(PDMS), surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the hydrophobic-substrate-containing AIDS-diagnosis multichannel microfluidic chip device aims to solve the series of relevant problems. Main points of the hydrophobic-substrate-containing AIDS-diagnosis multichannel microfluidic chip device are as follows: the PDMS with original ecological surface is selected as the substrate, a hinge-type fixture is manually fastened and positioned in a position near a sample flow terminal of the microfluidic chip to reduce interfacial tension by ultrasonic wave, wherein a miniature ultrasonic transducer is attached to the hinge-type fixture, meanwhile by use of strong ultrasonic wave absorption ability of the PDMS, a rapid ultrasonic wave intensity decline in a short distance can be achieved, so that interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to a subtype swine influenza detection apparatus with a fluid driving member being rapid to detach and belongs to the field of analysis and test. In the prior art, technical obstacles exist in a process of producing a substrate of a subtype swine influenza diagnosis micro-fluidic chip with polydimethylsiloxane (PDMS) which is low in cost and is easy to process. The PDMS has an intensive hydrophobic surface, and effects of specific surface modification and the like cannot be maintained durably, so that the invention aims to solve the related problems. In the embodiment, PDMS having an original ecologic surface is employed as the substrate, wherein an elastic clamp, of which a clamping arm is equipped with a micro-ultrasonic transducer, clamps and is located on a position nearby a terminal of a test sample fluid in the micro-fluidic chip through elasticity, so that ultrasonic wave reduces interface tension; and meanwhile, with the strong absorption capability of the PDMS to the ultrasonic wave, quick attenuation of intensity of the ultrasonic wave in a short distance is achieved, thus forming difference between the interface tensions at the two ends of the chip, so that the test sample fluid flows to the direction of the terminal along a capillary path which is originally hydrophobic.

The invention relates to a micro fluidic chip device capable of simultaneously detecting multiple typical tumor markers of female, and belongs to the field of analytical test. PDMS (polydimethylsiloxane) is used to manufacture the substrate of a microfluidic chip for combined detection of eight typical tumor markers, the combined detection is suitable for women, there are advantages of price and technology and problems, and the invention aims to solve the problems. PDMS with a raw surface is taken as the substrate; an elastic clamp, whose clamping arms are provided with a micro ultrasonic transducer, is clamped on a position, which is adjacent to the sample liquid flow terminal of the microfluidic chip, by the elastic force; ultrasonic waves are used to reduce the interfacial tension and increase the interfacial compatibility; at the same time, the strong performance of PDMS on absorbing ultrasonic waves is utilized, the strength of ultrasonic waves rapidly decreases in a short distance; thus difference of interfacial tension is formed between two ends of the microfluidic chip; the sample liquid flow is driven to the terminal through a hydrophobic capillary channel by the force generated by the difference, and the device does not need any micro pump.

The invention relates to an easily-disassembled cholera diagnosis device for liquid flow drive by means of interface characteristics and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for cholera diagnosis, a series of problems actually exist. The surface of the PDMS materialis strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS withprimitive surface is selected as the substrate, an elastic clamp with a miniature ultrasonic transducer attached to a clamping arm is in elastic snap-fit to be positioned near the terminal of a sampleliquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension difference between two ends of the chip. Thereby, the sample liquid fluid flows along the capillary channel towards the terminal.

The invention relates to a device for AIDS diagnosis using a hydrophobic material as the substrate of a microfluidic chip, belonging to the field of analysis and testing. It is a technical goal to use cheap and easy-to-process polydimethylsiloxane (PDMS) to make the substrate of microfluidic chips for AIDS diagnosis; however, the surface of this material is strongly hydrophobic, and targeted surface modification or Surface modification, its effect is difficult to last, this case aims to solve this series of related problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned at the position adjacent to the sample liquid flow terminal of the microfluidic chip, so as to Ultrasound reduces the interfacial tension, and at the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves in a short distance, thereby forming a difference in interfacial tension at both ends of the chip, thereby facilitating the flow of the sample along the original hydrophobic capillary The channel flows in the direction of the terminal.

The invention relates to a sub-type swine influenza detection chip device using PDMS as a substrate material and belongs to the field of analysis and testing. At present, there are a series of practical problems in preparation of a microfluidic chip substrate for sub-type swine influenza diagnosis through cheap and easily processed polydimethylsiloxane PDMS. The PDMS material has the strongly hydrophobic surface and the specifically improved or modified surface has no lasting effect. The sub-type swine influenza detection chip device solves the above problem. PDMS with the original ecological surface is selected as a substrate, a hinge fixture with a micro-ultrasonic transducer is manually fastened to a position close to a test sample liquid flow terminal of the microfluidic chip, a sample feeding end of the microfluidic chip is provided with an ultrasonic attenuator for fast degression of ultrasonic intensity in a short distance so that two ends of the chip form interfacial tension difference and the sample liquid flows to the terminal along a capillary channel direction.

The invention relates to a fluid-drive device with rapidly-removable components and for subtype swine influenza detection and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for subtype swine influenza diagnosis, there are many obstacles. The surface of the PDMS material is highly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, an elastic clamp with a miniature ultrasonic transducer attached to a clamping arm is in elastic snap-fit to be positioned near the terminal of a sample liquidfluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension difference between two ends of the chip. Thereby, the sample liquid fluid is driven to flow along an originally hydrophobic channel towards the terminal.

The invention relates to a liquid-flow-drive microfluidic device with rapidly-removable accessories and for cholera diagnosis and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for cholera diagnosis, a series of problems exist. The surface of the PDMS material is strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, an elastic clamp with a miniature ultrasonic transducer attached to a clamping arm is in elastic snap-fit to be positioned near the terminal of a sample liquid fluid ofthe microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension difference between two ends of the chip. Thereby, the sample liquid fluid flows along the capillary channel towards the terminal.

The invention relates to a microfluidic chip device for combined detection of six typical tumor markers, belonging to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for multi-channel combined detection of typical tumor markers. It has advantages and problems; this case addresses this problem. The main point of this case is that the PDMS with the original ecological surface is selected as the substrate, and the elastic clamp with the micro-ultrasonic transducer attached to the clamping arm is elastically positioned on the sample liquid flow terminal of the microfluidic chip and its neighbors. position, using ultrasonic waves to reduce the interfacial tension, greatly increasing the interfacial compatibility between the solid and liquid phases, and at the same time using the strong absorption capacity of PDMS for ultrasonic waves, the intensity of ultrasonic waves decreases rapidly within a short distance, thus forming at both ends of the chip The difference in interfacial tension thereby facilitates the flow of the sample fluid toward the terminal along the originally strongly hydrophobic capillary channel. The device eliminates the need for a micropump.

The invention relates to a microfluidic chip device for joint detection of multiple tumor markers with fifteen channels, belonging to the field of analysis and testing. PDMS, that is, polydimethylsiloxane, has obvious advantages if it is used to make the substrate of a microfluidic chip for the joint detection of more than ten kinds of tumor markers, but there are also some problems that need to be overcome; problem. The main point of this case is that the PDMS with the original ecological surface is selected as the substrate, and the elastic clamp with the micro-ultrasonic transducer attached to the clamping arm is elastically positioned on the sample liquid flow terminal of the microfluidic chip and its neighbors. position, using ultrasonic waves to reduce interfacial tension and increase interfacial compatibility. At the same time, the strong absorption ability of PDMS to ultrasonic waves can be used to achieve a rapid decrease in ultrasonic intensity in a short distance, thereby forming a difference in interfacial tension at both ends of the chip, thereby facilitating the test. The sample liquid flows toward the terminal along the originally hydrophobic capillary channel. The device does not require the use of micropumps.

The invention relates to a subtype swine influenza detection chip device using strong hydrophobic PDMS as a substrate material and belongs to the field of analysis and testing. At present, there are practical problems in preparation of a substrate of a microfluidic chip for diagnosing subtype swine influenza from cheap and easily processed polydimethylsiloxane PDMS. The PDMS material has the strongly hydrophobic surface and the specifically improved or modified surface has no lasting effect. The subtype swine influenza detection chip device solves the above problem. PDMS with the original ecological surface is selected as a substrate, a hinge fixture with a micro-ultrasonic transducer is manually fastened to a position close to a test sample liquid flow terminal of the microfluidic chip, a sample feeding end of the microfluidic chip is provided with an ultrasonic attenuator for fast degression of ultrasonic intensity in a short distance so that two ends of the chip form interfacial tension difference and the sample liquid flows to the terminal along a hydrophobic capillary channel direction.

The invention relates to a syphilis diagnosis multi-channel device with a microfluidic chip using a strong hydrophobic substrate and belongs to the field of analysis and testing. At present, there are practical problems in preparation of a microfluidic chip substrate for diagnosing syphilis through cheap and easily processed polydimethylsiloxane PDMS. The PDMS has the strongly hydrophobic surface and the specifically improved or modified surface has no lasting effect. The hydrophobic substrate-containing multi-channel microfluidic chip device solves the above problem. PDMS with the original ecological surface is selected as a substrate, a hinge fixture with a micro-ultrasonic transducer is manually fastened to a position close to a test sample liquid flow terminal of the microfluidic chip, a sample feeding end of the microfluidic chip is provided with an ultrasonic attenuator for fast degression of ultrasonic intensity in a short distance so that two ends of the chip form interfacial tension difference and the sample liquid flows to the terminal along a capillary channel direction.