89results about How to "Deter engulfment" patented technology

The invention relates to a subtype swine influenza detection device with an easy-to-remove liquid driving component, and belongs to the field of analytical testing. The subtype swine influenza detection device aims to solve related problems that various obstacles exist when cheap and easy-to-process polydimethylsiloxane (PDMS) is utilized to prepare a substrate of a micro-fluidic chip for subtype swine influenza diagnosis, and the effect of targeted surface modification or surface finish is difficult to last due to strong hydrophobicity of the surface of a PDMS material. The subtype swine influenza detection device is characterized in that the substrate adopts the PDMS with an original surface, an elastic clamp with clamping arms equipped with attached miniature ultrasonic transducers is elastically snapped and located in the position adjacent to a sample liquid flow terminal of the micro-fluidic chip, an ultrasonic attenuator is installed in the sample feeding end of the micro-fluidic chip to achieve rapid ultrasonic intensity decrease in a short distance, so that interfacial tension difference is formed at two ends of the chip, and the sample liquid flow is enabled to flow in a direction of the terminal along a capillary channel.

The invention relates to a dual-driving coupling operated micro-fluidic chip device used for syphilis diagnosis and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for syphilis diagnosis. But there exist some problems. The scheme aims to solve the problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure support each other, are intercoupling with each other, adjust and adapt mutually, and operate collaboratively.

The invention relates to a syphilis diagnosis microfluidic device with an easy-to-remove additional liquid flow driving component, and belongs to the field of analytical testing. A technical target is manufacture of a substrate of a syphilis-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the syphilis diagnosis microfluidic device with the easy-to-remove additional liquid flow driving component aims to solve the series of relevant problems. Main points of the syphilis diagnosis microfluidic device with the easy-to-remove additional liquid flow driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to an easily-dismountable multichannel device for cholera diagnosis and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane,namely PDMS for manufacturing a substrate of a microfluidic chip for cholera diagnosis, a series of problems exist. The surface of the PDMS material is strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, a chain-ring electromagnetic fixture attached with a miniature ultrasonic transducer is in cup joint to be positioned near the terminal of a sample liquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension differencebetween two ends of the chip. Thereby, the sample liquid fluid is driven to flow along an originally hydrophobic capillary channel towards the terminal.

The invention relates to an AIDS diagnosing device having an easily removably functional member used for driving an additionally added sample liquid, and belongs to the field of analysis testing. A technical objective is to prepare substrates of micro-fluidic chips used for AIDS diagnosis by utilizing polydimethylsiloxane, namely PDMS that is cheap and easy to process, but the PDMS material has a strongly hydrophobic surface, and targeted surface modification or surface decoration fails to achieve durable effects. The objective of the device is to overcome the series of problems. The device is characterized in that PDMS having an original surface is adopted as a substrate, a chain-ring type electromagnetic clamp equipped with a minitype ultrasonic transducer is positioned at a position near a sample liquid stream terminal of a micro-fluidic chip in a sleeve joint manner, and an ultrasonic attenuator is mounted at a feeding end of the micro-fluidic chip to achieve rapid ultrasonic wave intensity attenuation in a short distance, and therefore an interfacial tension difference is formed between the two ends of the chip, thus allowing the sample liquid stream to flow along originally hydrophobic capillary channels towards the terminal direction.

The invention relates to a six-channel micro-fluidic chip device for combined detection of abridged tumor markers, belonging to the field of analytical testing. The micro-fluidic chip device used for producing a substrate of the micro-fluidic chip for combined detection of classic tumor markers prepared from PDMS (polydimethylsiloxane) has advantages and a series of difficulties; and the invention aims at solving the series of difficulties. The invention is mainly characterized in that PDMS with originally ecological surface is selected as the substrate, a chain ring type electromagnetic clamp with a minitype ultrasonic energy transducer is sheathed at and positioned at a position close to the liquid flow end of a test sample of the micro-fluidic chip, the interfacial tension is reduced ultrasonically, so that the interfacial compatibility between the solid and liquid phases is greatly increased, the ultrasonic intensity is rapidly decreased progressively within short distance by utilizing the strong absorption capability of PDMS to ultrasonic wave, so that the interfacial tension difference is formed at the two ends of the chip, therefore, the liquid flow of the test sample is driven to flow to the end along the direction of originally hydrophobic capillary channel. The device does not use a micropump.

The invention relates to a micro-fluidic chip device for combined detection of multiple female classic tumor markers, belonging to the field of analytical testing. The micro-fluidic chip device used for producing a substrate of the micro-fluidic chip for combined detection of eight female classic tumor markers through PDMS (polydimethylsiloxane) has both price and technology advantages and difficulties. The invention aims at solving the difficulties. The invention has the characteristics that PDMS with originally ecological surface is selected as the substrate, a chain ring type electromagnetic clamp with a minitype ultrasonic energy transducer is sheathed at and positioned at a position close to the liquid flow end of a test sample of the micro-fluidic chip, the interfacial tension is reduced ultrasonically, so that the interfacial compatibility between the solid and liquid phases is greatly increased, the ultrasonic intensity is rapidly decreased progressively within short distance by utilizing the strong absorption capability of PDMS to ultrasonic wave, so that the interfacial tension difference is formed at the two ends of the chip, therefore, the liquid flow of the test sample is driven to flow to the end along the direction of originally hydrophobic capillary channel. The device does not use a micropump.

The invention relates to a micro-fluidic chip device with a dual driving coupling mode and used for diagnosis of AIDS and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for diagnosis of AIDS. But there exist a series of problems. The scheme aims to solve the series of problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure support each other and operate collaboratively. Thus, the problems are solved.

The invention relates to an acquired immune deficiency syndrome diagnosis micro-fluidic chip device adopting a dual drive coupling mode, and belongs to the field of analytical testing. When cheap polydimethylsiloxane, namely, PDMS easy to process is used for manufacturing a substrate of a micro-fluidic chip for acquired immune deficiency syndrome diagnosis, a series of problems exist. The scheme aims at the series of problems. According to the scheme, the PDMS with an original ecological surface is selected in the substrate, a micro ultrasonic transducer is fixedly installed at the position close to a sample liquid flow terminal of the micro-fluidic chip, interfacial tension is reduced through ultrasonic waves, meanwhile, the high absorption capacity of PDMS to the ultrasonic waves is utilized, the ultrasonic intensity is fast reduced within a short distance, and therefore an interfacial tension difference is formed between the two ends of the chip. Power for driving sample liquid flow to flow along a hydrophobic capillary channel in the terminal direction is provided through the difference, the power and the mechanical pumping power of a micropump included in the structure support each other and collaboratively operate, and the series of problems are all solved through the scheme.

The invention relates to an AIDS diagnosis device with an easily-detachable component used for driving a to-be-tested sample liquid, belonging to the fields of analysis and testing. The invention aimsto solve a series of related problems that manufacturing of a substrate of a microfluidic chip used for AIDS diagnosis from cheap and easily-processed polydimethylsiloxane (PDMS) has a technical obstacle; and the PDMS material has highly-hydrophobic surface and is difficult to obtain lasting effects through targeted surface modification or surface decoration. The invention has the following mainpoints: PDMS with original ecological surface is selected as the substrate; a link type electromagnetic fixture equipped with a miniature ultrasonic transducer is in sleeve connection with and is positioned at a position close to the terminal of a sample liquid flow of the microfluidic chip; ultrasonic wave is used to reduce the interfacial tension; meanwhile, strong absorption capacity of the PDMS to the ultrasonic wave is utilized, so rapid decrease of ultrasonic intensity in a short distance is realized, and an interfacial tension difference between two terminals of the chip is formed; thus, the sample liquid flow is driven to flow to the terminal direction along original hydrophobic capillary channels.

The invention relates to a micro-fluidic chip device used for diagnosis of AIDS and based on a dual-driving coupling operation mode and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for diagnosis of AIDS. But there exist a series of problems. The scheme aims to solve the series of problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure are intercoupling with each other. Thus, the problems are solved.

The invention relates to a multichannel cholera diagnosis micro-fluidic chip device operating in a double-drive coupling mode, and belongs to the field of analytical tests. A series of problems exist if polydimethylsiloxane, namely, PDMS which is cheap and very easy to process is used for manufacturing a substrate of a cholera diagnosis micro-fluidic chip, and the micro-fluidic chip device aims at solving the series of problems. The micro-fluidic chip device is characterized in that PDMS with an original surface is selected as a substrate, a micro ultrasonic transducer is fixedly installed at the position close to a sample liquid flow terminal of the micro-fluidic chip to reduce the interfacial tension with ultrasonic waves, meanwhile, the strong absorption capability of PDMS on ultrasonic waves is utilized to rapidly reduce the ultrasonic wave intensity within a short distance, and thus an interface tension difference is formed between the two ends of the chip; the difference provides a force driving sample liquid flow to flow towards the terminal along a hydrophobic capillary channel, and meanwhile the force cooperates with the mechanical pumping force of a micropump included in the structure. Thus, the series of problems are overall solved.

The invention relates to a dual-drive-coupling-operation-mode multichannel micro-fluidic chip device for cholera diagnosis, and belongs to the field of analysis testing. As a series of problems exist when a substrate of a micro-fluidic chip for cholera diagnosis is made by polydimethylsiloxane (PDMS) which is low in cost and extremely easy to process; for solving the series of problems, the dual-drive-coupling-operation-mode multichannel micro-fluidic chip device for cholera diagnosis is characterized in that the substrate is selected from the PDMS with the original ecology surface, a micro-ultrasonic transducer is fixedly installed at the adjacent position of the terminal of sample liquid flow of the micro-fluidic chip, and the interfacial tension is reduced through ultrasonic; meanwhile, the ultrasonic intensity is rapidly and progressively decreased in the short distance through the high absorbing capacity of the PDMS for the ultrasonic, the difference of interfacial tension is formed in the two ends of the chip accordingly, the difference provides force for driving the sample liquid flow to flow to the terminal direction along a hydrophobic capillary channel, the force and the mechanical pumping force of a micro-pump contained in the structure are coupled and collaboratively operate at the same time, and the series of problems are solved together.

The invention relates to a dual-drive coupled mode micro-fluidic chip device for detecting various subtype swine influenzas, and belongs to the field of analysis testing. Low-cost and easily processed PDMS (polydimethylsiloxane) is used for manufacturing a substrate of a micro-fluidic chip for subtype swine influenza diagnosis, and a series of obstacles exist. The device is used for eliminating the obstacles. The scheme mainly includes that the PDMS with an original ecological surface is selected as the substrate, a miniature ultrasonic transducer is fixedly mounted near a sample liquid flow terminal of the micro-fluidic chip, interfacial tension is reduced by ultrasonic waves, ultrasonic intensity is rapidly decreased in a short distance by high ultrasonic wave absorption capacity of the PDMS, so that interfacial tension difference is formed between two ends of the chip and provides force for driving sample liquid flow to flow towards the terminal along a hydrophobic capillary channel, and the force and the mechanical pumping force of a micro-pump in the structure are in collaborative operation to eliminate the obstacles.

The invention relates to an easily-detachable subtype swine influenza multichannel detection apparatus containing an electromagnetic auxiliary member, and belongs to the field of analytical testing. According to the present invention, the use of inexpensive and easily-processed polydimethylsiloxane (PDMS) to produce the substrate of a microfluidic chip for diagnosing subtype swine influenza has the following series of practical problems that the surface of the PDMS material is strongly hydrophobic and the effect of the targeted surface modification or surface modifying is difficult to lasting, and a purpose of the present invention is to solve the series of the related problems; and the apparatus is characterized in that the substrate selects the PDMS having an original ecological surface, a chain ring type electromagnetic fixture provided with a miniature ultrasonic wave transducer is sleeved and positioned at a position close to the sample liquid fluid terminal end of the microfluidic chip so as to reduce the interfacial tension through the ultrasonic wave, and the strong absorption capacity of the PDMS on the ultrasonic wave is used to rapidly decrease the intensity of the ultrasonic wave within a short distance, such that the interfacial tension difference is formed on both ends of the chip so as to promote the sample liquid fluid to flow to the terminal direction along the capillary channel.

The invention relates to a micro-fluidic chip device adopting coupling operation of two drive modes for syphilis diagnosis and belongs to the field of analysis and testing. Aiming at solving the problems caused by adoption of cheap and easy-to-process PDMS (polydimethylsiloxane) for manufacturing a substrate of a micro-fluidic chip for syphilis diagnosis, the scheme is characterized in that the substrate adopts PDMS with an original surface, a miniature ultrasonic transducer is fixedly mounted in the position adjacent to a sample liquid flow terminal of the micro-fluidic chip, interfacial tension is reduced through ultrasonic waves, meanwhile, the ultrasonic intensity is reduced progressively and rapidly in a short distance on the basis of high ultrasonic absorption capacity of PDMS, so that interfacial tension difference is formed between two ends of the chip, and power for driving sample liquid flow to flow towards the terminal along a hydrophobic capillary channel is provided by the difference and is mutually supported, mutually coupled, mutually adjusted and mutually cooperative with mechanical pumping power of a micropump in the structure simultaneously.

The invention relates to a microfluidic chip device for combined detection of various typical female tumor markers, which belongs to the field of analysis and testing. Using PDMS or polydimethylsiloxane to make the substrate of the microfluidic chip for the combined detection of eight typical tumor markers suitable for women has advantages in price and technology, but there are also difficulties; this case aims to overcome this difficulty . The main point of this case is that the substrate is selected from PDMS with an original ecological surface, and the link-type electromagnetic fixture equipped with a micro-ultrasonic transducer is socketed and positioned in the vicinity of the sample liquid flow terminal of the microfluidic chip. Ultrasound is used to reduce the interfacial tension, which greatly increases the interfacial compatibility between the solid and liquid phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming an interface at both ends of the chip. The difference in tension thereby facilitates the flow of the sample fluid toward the terminal along the originally hydrophobic capillary channel. The device eliminates the need for a micropump.