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131results about How to "Keep time short" patented technology

Device and method for holding sampling

The invention discloses a sample-and-hold amplifier which comprises a primary sample-and-hold circuit and a secondary sample-and-hold circuit. The input positive terminal and the input negative terminal of the primary sample-and-hold circuit receive an external signal, the output positive terminal and the output negative terminal of the primary sample-and-hold circuit are coupled to the input positive terminal and the input negative terminal of the secondary sample-and-hold circuit, the primary sample-and-hold circuit is provided with a primary operational amplifier with the amplification being less than a multiple, and the secondary sample-and-hold circuit is provided with a secondary operational amplifier which realizes the amplification more than the multiple; after the external signal is sampled, held and amplified, by the primary sample-and-hold circuit and the secondary sample-and-hold circuit, the external signal is output from the output positive terminal and the output negative terminal of the secondary sample-and-hold circuit. Meanwhile, the invention discloses a sample-and-hold method. The sample-and-hold amplifier, as a basic signal processing module, is used for front end processing of the external input signal; and the sample-and-hold amplifier ensures the speed and the precision of the signal conversion with the simple structure on the premise of realizing high reliability.
Owner:北京安策恒兴投资有限公司

Multi-channel microfluidic chip apparatus for simultaneous detection of a variety of subtype swine influenzas

The invention relates to a multi-channel microfluidic chip device for simultaneously detecting multiple subtypes of swine influenza, belonging to the field of analysis and testing. There are many obstacles in using cheap and easy-to-process polydimethylsiloxane (PDMS) to fabricate the substrate of microfluidic chip for subtype swine flu diagnosis; the surface of PDMS is strongly hydrophobic, and the effect of surface chemical modification is difficult to last. The main point of this case is that the substrate material is PDMS with an original surface, and the channels of the chip are filled with doped micron-sized titanium dioxide particles; the titanium dioxide particles are titanium dioxide that can induce super-hydrophilic properties on its surface through prior visible light irradiation Particles; the collection of super-hydrophilic channels between the particles of the titanium dioxide particle filler compensates and surpasses the original strong hydrophobic channel, thereby achieving a constant and super-hydrophilic modification effect; the titanium dioxide filler The function also includes preventing the collapse and deformation of the pipe of the chip, and preventing biological macromolecules from contacting the inner wall of the pipe.
Owner:李榕生

Microfluidic chip apparatus for multi-channel simultaneous detection of six typical tumor markers

The present invention relates to a microfluidic chip apparatus for multi-channel simultaneous detection of six typical tumor markers, and belongs to the field of analytical testing. According to the present invention, the use of inexpensive and easily-processed polydimethylsiloxane (PDMS) to produce the substrate of a microfluidic chip for multi-channel simultaneous detection of six typical tumor markers has a series of problems that the surface of the PDMS is strongly hydrophobic and the surface chemical modification effect is difficult to last. The technical scheme of the present invention is that the substrate material is PDMS with an original ecological surface, the pipeline of the chip is filled with doped micron-scale titanium dioxide particles, the surface super-hydrophilicity of the titanium dioxide particles can be induced by visible light irradiation in advance, and the set of the titanium dioxide particle filler and the super-hydrophilic gap between the particles can compensate and beyond the original strong hydrophobic pipeline, such that the constant and super hydrophilic modification effect is achieved. In addition, the titanium dioxide filler can further be used for preventing the pipeline of the chip from collapsing and deforming, and blocking biological macromolecules from contacting the inner wall of the pipeline.
Owner:李榕生

Microfluidic chip apparatus suitable for females and used for combined detection of typical tumor markers

The present invention relates to a microfluidic chip apparatus suitable for females and used for combined detection of typical tumor markers, and belongs to the field of analytical testing. According to the present invention, the use of PDMS to produce the substrate of a microfluidic chip suitable for females and used for combined detection of typical tumor markers has a series of problems that the surface of the PDMS is strongly hydrophobic and the surface chemical modification effect is difficult to last. The technical scheme of the present invention is that the substrate material is PDMS with an original ecological surface, the pipeline of the chip is filled with doped micron-scale titanium dioxide particles, the surface super-hydrophilicity of the titanium dioxide particles can be induced by visible light irradiation in advance, and the set of the titanium dioxide particle filler and the super-hydrophilic gap between the particles can compensate and beyond the original strong hydrophobic pipeline, such that the constant and super hydrophilic modification effect is achieved. In addition, the titanium dioxide filler can further be used for preventing the pipeline of the chip from collapsing and deforming, and blocking biological macromolecules from contacting the inner wall of the pipeline.
Owner:李榕生

Subtype swine influenza detection chip apparatus with strongly-hydrophobic PDMS substrate

The present invention relates to a subtype swine influenza detection chip apparatus with a strongly-hydrophobic PDMS substrate, and belongs to the field of analysis and testing. According to the present invention, the use of inexpensive and easily-processed polydimethylsiloxane (PDMS) to produce the substrate of a microfluidic chip for diagnosing subtype swine influenza has a plurality of barriers; and the subtype swine influenza detection chip apparatus is characterized in that the substrate selects the PDMS having an original ecological surface, a hinge type fixture provided with a miniatureultrasonic wave transducer is manually fastened and positioned at the position close to the sample liquid flow terminal of the microfluidic chip, ultrasonic waves induce the sample liquid flow to flow from the sample injection end of the chip to the terminal direction along the pipeline of the chip, the pipeline of the chip is filled with a micro-scale silica particle filler, and the micro-scalesilica particle filler is used for supporting the inner wall of the pipeline, compensating the original hydrophobic pipeline with the set of hydrophilic micro-flow channels, and extruding and coveringthe inner wall surface of the pipeline so as to reduce the opportunity of the contact between biological macromolecules and the inner wall surface.
Owner:葛光奇

Acquired immunodeficiency syndrome diagnosis apparatus having easily-detachable member and used for liquid flow drive

The present invention relates to an acquired immunodeficiency syndrome diagnosis apparatus having an easily-detachable member and used for liquid flow drive, and belongs to the field of analysis and testing. In the prior art, the application of the inexpensive and highly-processable polydimethylsiloxane (PDMS) to produce the substrate of the acquired immunodeficiency syndrome diagnosis microfluidic chip has a series of problems. The technical scheme of the present invention is that PDMS having an ecosystem surface is selected as a substrate, an elastic force clamper additionally provided with a miniature ultrasonic wave transducer on the clamping arm is engaged and positioned at the position close to the sample liquid flow terminal end of a microfluidic chip through elastic force, ultrasonic waves induce a sample liquid flow to flow to the terminal end direction from the sample injection end of the chip along the pipeline of the chip, the pipeline of the chip is filled with a micro-scale silica particle filler, and the micro-scale silica particle filler is used for supporting the inner wall of the pipeline, compensating the original hydrophobic pipeline with a hydrophilic micro-channel, and extruding and covering the inner wall surface of the pipeline so as to reduce the opportunity of the contact between biological macromolecules and the inner wall surface.
Owner:李榕生

Inexpensive cholera diagnosis microfluidic apparatus with tortuous liquid flow transmission route

The present invention relates to an inexpensive cholera diagnosis microfluidic apparatus with a tortuous liquid flow transmission route, and belongs to the field of analytical testing. According to the present invention, the use of inexpensive and easily-processed polydimethylsiloxane (PDMS) to produce the substrate of a microfluidic chip for cholera diagnosis has a series of problems that the surface of the PDMS is strongly hydrophobic and the surface chemical modification effect is difficult to last. The technical scheme of the present invention is that the substrate material is PDMS with an original ecological surface, the pipeline of the chip is filled with doped micron-scale titanium dioxide particles, the surface super-hydrophilicity of the titanium dioxide particles can be induced by visible light irradiation in advance, and the set of the titanium dioxide particle filler and the super-hydrophilic gap between the particles can compensate and beyond the original strong hydrophobic pipeline, such that the constant and super hydrophilic modification effect is achieved. In addition, the titanium dioxide filler can further be used for preventing the pipeline of the chip from collapsing and deforming, and blocking biological macromolecules from contacting the inner wall of the pipeline.
Owner:李榕生
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