Multi-channel microfluidic chip apparatus for simultaneous detection of a variety of subtype swine influenzas

A microfluidic chip, swine flu technology, applied in the field of analysis and testing, can solve problems such as large flow resistance, troublesome modification of the inner surface of the PDMS channel, and has not been properly solved.
CN107490702AInactive Publication Date: 2017-12-19ๆŽๆฆ•็”Ÿ
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
ๆŽๆฆ•็”Ÿ
Publication Date
2017-12-19
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The invention relates to a multi-channel microfluidic chip device for simultaneously detecting multiple subtypes of swine influenza, belonging to the field of analysis and testing. There are many obstacles in using cheap and easy-to-process polydimethylsiloxane (PDMS) to fabricate the substrate of microfluidic chip for subtype swine flu diagnosis; the surface of PDMS is strongly hydrophobic, and the effect of surface chemical modification is difficult to last. The main point of this case is that the substrate material is PDMS with an original surface, and the channels of the chip are filled with doped micron-sized titanium dioxide particles; the titanium dioxide particles are titanium dioxide that can induce super-hydrophilic properties on its surface through prior visible light irradiation Particles; the collection of super-hydrophilic channels between the particles of the titanium dioxide particle filler compensates and surpasses the original strong hydrophobic channel, thereby achieving a constant and super-hydrophilic modification effect; the titanium dioxide filler The function also includes preventing the collapse and deformation of the pipe of the chip, and preventing biological macromolecules from contacting the inner wall of the pipe.
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Description

technical field

[0001] The invention relates to a multi-channel microfluidic chip device for simultaneously detecting multiple subtypes of swine influenza, belonging to the field of analysis and testing. Background technique

[0002] For the technical background of multi-channel microfluidic subtype swine influenza diagnosis, please refer to CN 201110311127.1 and other invention patent applications.

[0003] As far as the overall overview of microfluidic technology itself is concerned, you can refer to the monograph "Illustrated Microfluidic Chip Laboratory" published by the famous microfluidic expert Mr. Lin Bingcheng not long ago, which has been published by Science Press. The past, present, and future prospects of microfluidic technology, etc., have detailed and long-form discussions that go deep into specific details.

[0004] So, let's talk about the key issues of this case.

[0005] The basic structure of a microfluidic chip includes a substrate etched with channels ...

Claims

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