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7 results about "Capsular contracture" patented technology

Capsular contracture is a response of the immune system to foreign materials in the human body. Medically, it occurs mostly in context of the complications from breast implants and artificial joint prosthetics.

Composite amnion for improving contracture after tissue repair operation

The invention discloses a composite amnion for improving contracture after tissue repair and a preparation method of the composite amnion. The composite membrane comprises a recombinant humanized collagen nanofiber membrane located in the middle layer and human decellularized amniotic membranes attached to the two faces of the nanofiber membrane. The composite membrane is prepared by preparing a recombinant humanized collagen nanofiber membrane through an electrostatic spinning technology and pressing the recombinant humanized collagen nanofiber membrane and a human decellularized amniotic membrane. The composite membrane has excellent mechanical properties and biological activity. Animal experiment results show that the composite film can effectively inhibit capsule contracture induced by radiotherapy, and the comprehensive effect of the composite film is obviously superior to that of a single-component material in the aspects of inflammation resistance, fibrosis resistance, degradation speed delaying, capsule compliance improving and the like. The composition can be used for improving the capsule contracture of the breast prosthesis, especially the capsule contracture induced by radiotherapy.
Owner:SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV +1

Tissue expander for breast reconstruction capable of MMP sensor-based real-time capsular contracture monitoring and treatment, and patient information system linked thereto

Disclosed are a tissue expander for breast reconstruction comprising an MMP sensor and thus being capable of real-time capsular contracture monitoring and treatment, and a patient information system linked thereto. According to these, a patient or medical staff can easily check and evaluate capsular contracture, which may occur when wearing a tissue expander for breast reconstruction, and whether inflammation, a side effect, or the like is caused thereby, even outside the human body in real time. Accordingly, before or when capsular contracture occurs, effective treatment and response are possible.
Owner:SEOUL NAT UNIV HOSPITAL +1

Degradable breast prosthesis shaping mesh having heterogeneous hierarchical porous structure and preparation method therefor

PCT designated stageWO2026108318A1Mammary implantsBreast prosthesesHierarchical porous
Disclosed is a degradable breast prosthesis shaping mesh (10) having a heterogeneous hierarchical porous structure, comprising a macroporous structure layer (100) and a microporous structure layer (200). The macroporous structure layer (100) and the microporous structure layer (200) are formed by alternately arranging and combining degradable fibers to conform to a breast prosthesis, thereby providing the mechanical properties and tissue adhesion properties required by the mesh (10). The macroporous structure layer and the microporous structure layer cooperate to achieve the function of integrating the prosthesis with the tissue, without the need for an additional suturing fixation device. The overall shape of the mesh (10) is designed as a hemispherical upper cover (11) and a lower end cover rim (12), thereby simplifying the assembly process with the prosthesis and improving the surgical efficiency. The mesh (10) possesses excellent mechanical properties and shaping ability. Moreover, a microporous structure facilitates the adhesion and migration of cells, reduces the rejection reaction of the body, and significantly reduces the incidence of capsular contracture.
Owner:SHENZHEN BIOREGENERATION TECHNOLOGY CO LTD