33 results about "Post injury" patented technology

A biomimetic biosynthetic nerve implant (BNI) that uses a hydrogel-based, transparent, multi-channel matrix as a 3-D substrate for nerve repair is disclosed. Novel scaffold-casting devices were designed for reproducible fabrication of grafts containing several micro-conduits, and further tested in vivo using a sciatic nerve animal model and repair of the adult hemitransected spinal cord. At 16 weeks post-injury of the sciatic nerve, empty tubes formed a single nerve cable. In sharp contrast, animals that received the multi-luminal BNI showed multiple nerve cables within the available microchannels, better resembling the multi-fascicular anatomy and ultra structure of the normal nerve. In the injured spinal cord, the BNI loaded with genetically engineered Schwann cells were able to demonstrate survival of the grafted cells inside the BNI, and robust axonal regeneration through the implant up to 45 days after repair.

In the present invention, Applicants demonstrate the effect of a biomembrane sealing agent on the development of chronic pain following tissue injury as well as acute pain in a model of acute inflammation. Applicants demonstrate the ability of this class of agents referred to as “biomembrane sealing agents” to reduce the severity of hyperalgesia and allodynia following mechanical insult to the nervous system as well as their ability to reduce acute pain in a model of acute inflammation. Applicant describes the use of injectable or depot formulations of biomembrane sealing agent(s) for prophylactic treatment such as they could be administered after the insult (i.e. post-injury or post-surgery) but before the onset of acute or chronic pain. Alternatively, biomembrane sealing agents could be used to reduce the severity of acute or chronic pain after onset.

This invention provides a lower-limb off-axis movement training apparatus, which is mounted on the movement part of a sagittal plane exercise machine and allows the user to perform off-axis movement training during sagittal plane functional movements. The said apparatus for the lower limb off-axis training consists of a base, an off-axis movement generating part mounted on the base, and a foot container supported by the off-axis movement generating part. The said off-axis movement generating part comprising at least one of the following two: (1) off-axis pivoting generating part, which generates the pivoting movement of the foot container; (2) off-axis sliding generating part, which generates the sliding movement of the foot container. A feedback training system including the said training apparatus is provided. While the user performs sagittal plane movements of the lower limbs, the said system provides off-axis movement training integrated with the sagittal plane movements. The invented off-axis training apparatus and system can be used to help human subjects improve off-axis and sagittal plane neuromuscular control, reduce the incidence of lower limb injuries and facilitate post-injury rehabilitation.

Embodiments of the present invention generally relate to methods of preventing injury to a person related to job demand. Embodiments generally include comparative monitoring of the current status of the person as related to one or more job demands. The current status is compared to both previous status and desired status to help prevent injury and speed recovery post-injury.

The invention relates to a new use of a butyric acid producing beneficial bacterium, in particular to one or more applications of the butyric acid producing beneficial bacterium in preparing a preparation for preventing and treating a severe disease gut barrier injury and post-injury complication, wherein the prevention and treatment of the gut barrier injury and post-injury complication of the severe disease is a prevention an treatment function on the gut barrier which is realized by producing the butyric acid in the intestinal tract, introducing the butyric acid into the intestinal tract, providing intestinal mucosa energy, promoting cell proliferation of the intestinal mucosa, restricting the cell apoptosis of the intestinal mucosa, improving the permeability of the intestinal mucosa and preventing and curing the intestinal mucosa carrier.

A device for providing thermal therapy for post-surgery or post-injury recovery of the breast region is provided. The thermal therapy device includes a bladder for allowing temperature-controlled fluid to flow throughout the bladder and a shell for holding the bladder. The bladder can include holes to increase its conformability to irregular three-dimensional shapes. One or more splints on the shell help to stabilize the breasts and a layer provides insulation to the bladder. The device is designed to be separable in the front, thereby allowing it to be easily worn and removed.

Portable powered stretching exosuit (PPSE) systems and methods according to various embodiments are described herein. The PPSE can be used to facilitate stretching routines for athletics, rehabilitation, or for therapeutic purposes such as maintaining mobility for DMD patients. The PPSE is comfortable, relatively easy to don and doff, and in a form factor such that the PPSE can be worn during thewearer's normal activities. The PPSE may be self-powered, and automatically perform or assist with specific stretching routines. PPSEs may be optimized for one or more specific stretches, whether forathletic performance, medical purposes or rehabilitation following surgery or injury.

The compositions and methods of described herein comprise novel ingredients effective to reduce unwanted pigmentation, such as skin discoloration, freckles, age spots, liver spots, sun damage, tans, pigmented acne marks, scars, pigmented birthmarks, hyperpigmentation, post-inflammatory hyperpigmentation, post-injury hyperpigmentation, melasma, cholasma, after-burn scar, nail stain, yellowing of skin, dark circles under eyes, and the like. The composition may include additional ingredients accordingly for a colored cosmetic, moisturizer, cleanser, toner, and the like.

In the present invention, the applicants describe methods and compositions of treating damaged cardiovascular elements and cardiovascular conditions including hypotension, atherosclerotic lesions, vulnerable plaque, and acute myocardial infarct. The applicants demonstrate the ability of a biomembrane sealing agent to accumulate on the walls of damaged blood vessels and help improving mean arterial pressure following tissue injury. The applicants describe the use of formulations comprising at least one biomembrane sealing agent and one bioactive agent for prophylactic treatment such as they could be administered concurrently to an invasive therapeutic intervention or after the insult (i.e. post-injury or post-surgery). Alternatively, these methods and compositions could be used to reduce the severity of cardiovascular diseases after onset.

This invention discloses a therapeutic post-injury pressure glove and a method to produce the same. The pressure glove is configured to apply pressure onto a plurality of pressure-receiving regions of an injured hand such that each pressure-receiving region receives a pressure within an upper bound and a lower bound determined therefor. In one embodiment, the pressure glove comprises a plurality of custom pressure-applying fabric portions each of which is configured to direct a pressure onto one of the pressure-receiving regions. A suitable fabric specific for each fabric portion is selected so that adequate pressure is provided on a wounded area while maintaining a low pressure on an intact part of the hand. The pressure glove is fabricated with a size less than the hand's size by a reduction factor. The reduction factor and the set of selected fabrics are determined via obtaining a computed pressure distribution.

Belonging to the pharmaceutical field, the invention relates to application of nicotinamide phosphoribosyltransferase (NAMPT) in preparation of neuroprotective and rehabilitation drugs. Experiments of the invention show that NAMPT recombinant protein can penetrate the blood-brain barrier to significantly reduce the volume of ischemic brain injury and alleviate white matter injury after ischemic brain injury; the NAMPT recombinant protein can significantly improve long-term behaviors after ischemic brain injury; the NAMPT recombinant protein can raise revascularization related factors to enhance revascularization after brain hypoxia and neuron regeneration after brain hypoxia, and promote post-injury neurologic function reestablishment; and by mediating oligodendrocyte regeneration and alleviating the demyelination effect of local lysolecithin, the NAMPT recombinant protein can promote restoration of white matter after injury and strengthen post-injury neurologic function reestablishment. Results show that the NAMPT recombinant protein plays a long-term neuroprotective role in drugs treating cerebral stroke, traumatic brain injury and multiple sclerosis, and can be used as a neuroprotective drug to treat acute and chronic injury caused by brain stroke.

The invention relates to a medicament for treating hyperosteogeny, which is prepared by grinding the following materials into powder in percentage by weight: 8 to 15 percent of alpine yallow herb (prepared), 7 to 14 percent of seed of cowherb, 8 to 14 percent of brook anemone, 7 to 15 percent of ranunculus sceleratus, 8 to 14 percent of nux vomica (prepared), 7 to 13 percent of oblongleaf kadsura stem or root, 6 to 13 percent of Chinese hydrangeavine root-bark, 8 to 13 percent of trident maple (prepared), 7 to 16 percent of Chinese alangium (prepared), and 7 to 15 percent of caulis impatientis. The medicament is for external use, has obvious curative effects of treating the hyperosteogeny, unknown sores or boils, post injury bone ache and various arthralgia, and is mixed with boiled water in use and is applied to an affected part which is then bandaged.

The invention relates to a protecting and repairing material for a post-injury uterine cavity and a preparation method thereof. The protecting and repairing material for the post-injury uterine cavity, provided by the invention, is prepared from the following raw materials in percentage by weight (based on total weight of the raw materials): 5% to 55% of polyoxyethylene-polyoxypropylene ether block copolymer, 0.1% to 3% of sodium alginate, 1% to 25% of glycerine, 5% to 15% of polyalcohol and the balance of pure water. The protecting and repairing material for the post-injury uterine cavity, provided by the invention, is unique in performance and convenient in use and is a gel material which is good in biocompatibility and is safe, non-toxic and nonirritant; due to unique temperature response performance, the protecting and repairing material can be used for rapidly and comprehensively covering a uterine wound surface in a liquid fluid state and forming a stable gel state under the condition of body temperature, so as to effectively isolate the wound surface and effectively protect the wound surface of surgical operation. The gel material has an extremely high application value in uterine cavity injury protection.

The present invention relates to a general surgery burn treatment device, belonging to the technical field of medical instruments. The device comprises a body. The lower side of the body is provided with supporting legs, and two sides of each of the supporting legs are provided with brake metal strips. The inner sides of the supporting legs are provided with alloy connection rods. The lower sides of the supporting legs are provided with small rubber wheels. The right side of the body is provided with an alloy frame plate. The upper side of the alloy frame plate is provided with a chassis fixed ring. The upper side of the chassis fixed ring is provided with a vertical hard plastic rod. The left side of the vertical hard plastic rod is provided with a supplement liquid heating tube. The upper side of the vertical hard plastic rod is provided with a body fluid bottle rack. The upper side of the body fluid bottle rack is provided with a body fluid bottle fixing device. The general surgery burn treatment device has the advantages of full functions and convenience in use, when medical personnel carry out post-injury treatment, time and labor are saved, the device is scientific and convenient, safe and efficient, intelligent and accurate, and the difficulty of treatment of the medical personnel is reduced.

The invention discloses a method for evaluating the influence of the earthquake on the stability and the safety of a side slope. The method can be used for analyzing the stability and the safety of a side slope during and after an earthquake. The method for evaluating the influence of the earthquake on the stability and the safety of the side slope comprises the steps of (1), calculating the earthquake dynamic effect on a side slope structure containing a dam slope based on an ideal elastoplastic model of the rock and earth mass and the finite element method of the earthquake time process to obtain a plastic strain region of the side slope; (2) for the obtained plastic strain region, calculating the seepage field and the stress field of the side slope based on earthquake post-injury parameters, analyzing and analyzing the stability of the side slope structure during the variation of the side slope in rainfall, reservoir water level, slope excavation and other induced conditions after the earthquake; (3), comparing the result of the step (2) with that irrespective of the earthquake effect to obtain the influence of the earthquake on the stability and the safety of the side slope.

A method of treating traumatic brain injury (TBI) and other neurological disorders is presented herein. Both conditioned media (CM) containing long non-coding RNAs such as NEAT1 (nuclear enriched abundant transcript 1) and MALAT1 (metastasis associated lung adenocarcinoma transcript 1) as well as human adipose-derived stem cells (hADSCs) themselves (Tx), when administered at least 3 hours post injury, were found to significantly ameliorate motor and cognitive functions in young, but not aged, mice undergoing TBI. Significant reduction in cortical damage and hippocampal cell loss was observed in both Tx and CM groups in young rats, whereas less neuroprotection was detected in the aged rats and mainly in the Tx group but not the CM group, which may in part result from decreased homing of the cells to the spleen.

A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines, and further comprising 1 or more terminal cysteines. The composition is administered in therapeutically effective dosages prophylactic ally as soon as possible post-injury in treating neuronal injury.

The invention relates to the technical field of medical instruments, and discloses a bed body bracket for recovery after ankle injury. The bracket comprises a bed body, a supporting mechanism is arranged at the top of the bed body, the supporting mechanism comprises limiting frames, a supporting plate and a containing plate, the two limiting frames are arranged on the left side and the right sideof the top of the bed body respectively, the containing plate is arranged on the supporting plate, and fastening mechanisms are arranged between the two limiting frames and the bed body. According tothe bed body bracket for recovery after ankle injury, a silica gel protection pad is arranged on the concave inner wall of the containing plate, the silica gel protection pad is contacted with a humanbody, rigid contact between the human body and the containing plate is reduced, and pain and discomfort brought to the human body are also reduced. The containing plate is arranged to be concave, thehuman body habit of an ankle wounded person lying on a bed for rehabilitation is met, the contact position and angle of the wounded ankle part can be properly changed on the containing plate, and theproblem that in the rehabilitation process, the foot posture is not moved for a long time, and consequently blood circulation is poor is solved.

The present invention relates to a general surgery burn treatment device, belonging to the technical field of medical instruments. The device comprises a body. The lower side of the body is provided with supporting legs, and two sides of each of the supporting legs are provided with brake metal strips. The inner sides of the supporting legs are provided with alloy connection rods. The lower sides of the supporting legs are provided with small rubber wheels. The right side of the body is provided with an alloy frame plate. The upper side of the alloy frame plate is provided with a chassis fixed ring. The upper side of the chassis fixed ring is provided with a vertical hard plastic rod. The left side of the vertical hard plastic rod is provided with a supplement liquid heating tube. The upper side of the vertical hard plastic rod is provided with a body fluid bottle rack. The upper side of the body fluid bottle rack is provided with a body fluid bottle fixing device. The general surgery burn treatment device has the advantages of full functions and convenience in use, when medical personnel carry out post-injury treatment, time and labor are saved, the device is scientific and convenient, safe and efficient, intelligent and accurate, and the difficulty of treatment of the medical personnel is reduced.

The invention relates to a rehabilitation medical device, in particular to a rehabilitation medical device for injured arms. The rehabilitation medical device for the injured arms can relieve muscle tension through massage. A rehabilitation medical device for an injured arm comprises a bottom plate, a connecting seat, a bearing seat, a platform, square connecting rods, an exercising mechanism and a massage mechanism, the connecting seat is slidably arranged on the bottom plate, the bearing seat for a patient to sit on is slidably arranged on the connecting seat, and the square connecting rods are arranged on the left side and the right side of the front side of the bottom plate. A platform for a patient to place arms is slidably arranged between the connecting square rods, an exercising mechanism for the patient to exercise the arms is arranged on the front side of the upper portion of the platform, and a massage mechanism for massaging the big arms of the patient is arranged on the rear side of the platform. The upper arms of a patient are massaged through the front pin rollers and the rear pin rollers, so that muscle tension is relieved, and the exercising effect of the two arms is good.

The invention discloses a preparation method for an external medicine for nerve post-injury and components of the external medicine. The preparation method for the external medicine for the nerve post-injury comprises the following steps: fetching 10 to 30 parts of solanum lyratum thumb, 6 to 12 parts of glossy privet fruit, 6 to 12 parts of Cassia alata L, 1 to 5 parts of Viburnum foetidrm Wall, 3 to 9 parts of Amblystegium serpens, 15 to 25 parts of medicinal cyathula root, 6 to 12 parts of erycibe obtusifolia benth, 2 to 20 parts of securinega suffruticosa, 6 to 12 parts of bighead atractylodes rhizome, 2 to 10 parts of scandent schefflera stem and leaf, 6 to 12 parts of Acmella ciliate, 1 to 5 parts of glechoma longituba, 2 to 10 parts of fresh ginger, 1 to 5 parts of lobed kudzuvine root, 1 to 9 parts of mint, 5 to 15 parts of fructus forsythia, 3 to 9 parts of Poria cocos and 3 to 9 parts of Schisandra chinensis, mixing, adding water for decocting; removing filtrate after 30 minutes; adding water to dregs of decoction to go on decocting for 20 minutes, and then fetching filtrate, combining the filtrate of the two times, concentrating, drying and crushing, and then, mixing for applying. The external medicine disclosed by the invention has a unique stasis removal effect, is capable of promoting growth and development and axonal regeneration and the maintenance of the synaptic function of nerve fibers, is capable of deciding and inducing nervous processes to grow along a correct direction in redevelopment and regeneration of a nervous system, cannot cause normal axons to sprout, also has multiple effects of stopping pain, dissipating blood stasis and promoting blood circulation to remove meridian obstruction and is in favor of the treatment and recovery of the nerve post-injury.

The invention discloses a bullet wound dressing change device, and relates to the technical field of bullet wound dressing change. In order to solve the problem that after a common individual soldier is injured in a field operation, wound binding is not good, the following scheme is provided, the bullet wound dressing change device comprises a first arc-shaped elastic plate and a second arc-shaped elastic plate, wherein multiple fixing blocks are symmetrically arranged on the front side and the back side of the first arc-shaped elastic plate; a supporting and tensioning device is hinged between every two adjacent fixing blocks on the same side; a wound fixing device is fixedly arranged on the outer wall of the bottom of the second arc-shaped elastic plate; L-plates are symmetrically and fixedly connected to the bottom of the second arc-shaped elastic plate; and rectangular sleeves are symmetrically and fixedly connected to the bottom of the first arc-shaped elastic plate. The bullet wound dressing change device is novel in design and easy to operate, the effect of conveniently adjusting the length of a connecting belt is achieved, the device can be suitable for fixing different parts of the human body, meanwhile, pressure at the pressed position of the wound can be conveniently and finely adjusted, and the better effect of assisting in dressing change binding can be achieved.

The invention provides a mouse derma damage modeling tool for medical experiment. The mouse derma damage modeling tool comprises a bottom plate and a housing, wherein the housing is fixedly arranged on the outer side surface of the bottom plate; a four-limb fixing mechanism and a trunk fixing mechanism are arranged on the upper surface of the bottom plate; a mounting frame is fixedly arranged on the outer side surface of the housing; a PLC is mounted on the side surface of the mounting frame; and the input end of the PLC is electrically connected with the output end of an external power source. According to the mouse derma damage modeling tool for medical experiment disclosed by the invention, through the four-limb fixing mechanism and the trunk fixing mechanism, a mouse can be conveniently fixed, so that the situation that after being injured, the mouse wallops and is out of control is avoided, the working efficiency is improved, and experimental research is facilitated; besides, a damaging tool is mounted on a sliding rod through a mounting block, so that the damage position can be conveniently regulated through regulating the sliding rod; and a driving motor is driven to rotate,so that derma of different sizes can be cut, the using flexibility is increased, the operation is easy, and the using is convenient.

The invention discloses a method for evaluating the influence of the earthquake on the stability and the safety of a side slope. The method can be used for analyzing the stability and the safety of a side slope during and after an earthquake. The method for evaluating the influence of the earthquake on the stability and the safety of the side slope comprises the steps of (1), calculating the earthquake dynamic effect on a side slope structure containing a dam slope based on an ideal elastoplastic model of the rock and earth mass and the finite element method of the earthquake time process to obtain a plastic strain region of the side slope; (2) for the obtained plastic strain region, calculating the seepage field and the stress field of the side slope based on earthquake post-injury parameters, analyzing and analyzing the stability of the side slope structure during the variation of the side slope in rainfall, reservoir water level, slope excavation and other induced conditions after the earthquake; (3), comparing the result of the step (2) with that irrespective of the earthquake effect to obtain the influence of the earthquake on the stability and the safety of the side slope.

The present invention relates to an immersible, adjustable, surface compliant device and methods of using it an environment with variable, induced current flows for purposes of exercise, rehabilitation, or pure fun. The adjustable, immersible, surface compliant device can be used in pools, water tanks, or any body of water having a location where the device could be attached. The adjustable, immersible, surface compliant device and methods of using it are ideal for rehabilitating an injury, assisting aging bodies in performing exercises, and allowing the permanently injured to achieve movement and some degrees of physical autonomy despite being injured. In some embodiments, I disclose a trampoline-like device, having adjustable surface compliance, to be used in a pool or water tank having a current flow, wherein the angle of the trampoline is horizontally adjustable.

The compositions and methods of described herein comprise novel ingredients effective to reduce unwanted pigmentation, such as skin discoloration, freckles, age spots, liver spots, sun damage, tans, pigmented acne marks, scars, pigmented birthmarks, hyperpigmentation, post-inflammatory hyperpigmentation, post-injury hyperpigmentation, melasma, cholasma, after-burn scar, nail stain, yellowing of skin, dark circles under eyes, and the like. The composition may include additional ingredients accordingly for a colored cosmetic, moisturizer, cleanser, toner, and the like.

The invention discloses a protective device for injured fingers in a basketball game and relates to the field of sport injury. The protective device for injured fingers in a basketball game comprises a first elastic fixing band, connecting bands, finger shaping devices and folding devices, the connecting bands are arranged on the first elastic fixing band, the finger shaping devices are arranged on the connecting bands, the folding devices are arranged on the finger shaping devices, each folding device is composed of first fixing blocks, second fixing blocks, first connecting rods, second connecting rods, liquid absorbing cotton and sweat-absorbing non-slip mats, the sweat-absorbing non-slip mats and the first connecting rods are arranged on the first fixing blocks, the sweat-absorbing non-slip mats and the second connecting rods are arranged on the second fixing blocks, the first connecting rods are connected with the second connecting rods, and the liquid absorbing cotton is arranged between the first fixing blocks and the second fixing blocks. The protective device for injured fingers in a basketball game has a reasonable and practical structure, is convenient to use, can quickly stop bleeding, prevents blood from flowing out, protects a wound against secondary injury caused by movement, and accelerates recovery of the wound of a patient.