33 results about "Post injury" patented technology

In the present invention, Applicants demonstrate the effect of a biomembrane sealing agent on the development of chronic pain following tissue injury as well as acute pain in a model of acute inflammation. Applicants demonstrate the ability of this class of agents referred to as “biomembrane sealing agents” to reduce the severity of hyperalgesia and allodynia following mechanical insult to the nervous system as well as their ability to reduce acute pain in a model of acute inflammation. Applicant describes the use of injectable or depot formulations of biomembrane sealing agent(s) for prophylactic treatment such as they could be administered after the insult (i.e. post-injury or post-surgery) but before the onset of acute or chronic pain. Alternatively, biomembrane sealing agents could be used to reduce the severity of acute or chronic pain after onset.

This invention provides a lower-limb off-axis movement training apparatus, which is mounted on the movement part of a sagittal plane exercise machine and allows the user to perform off-axis movement training during sagittal plane functional movements. The said apparatus for the lower limb off-axis training consists of a base, an off-axis movement generating part mounted on the base, and a foot container supported by the off-axis movement generating part. The said off-axis movement generating part comprising at least one of the following two: (1) off-axis pivoting generating part, which generates the pivoting movement of the foot container; (2) off-axis sliding generating part, which generates the sliding movement of the foot container.

A feedback training system including the said training apparatus is provided. While the user performs sagittal plane movements of the lower limbs, the said system provides off-axis movement training integrated with the sagittal plane movements. The invented off-axis training apparatus and system can be used to help human subjects improve off-axis and sagittal plane neuromuscular control, reduce the incidence of lower limb injuries and facilitate post-injury rehabilitation.

Embodiments of the present invention generally relate to methods of preventing injury to a person related to job demand. Embodiments generally include comparative monitoring of the current status of the person as related to one or more job demands. The current status is compared to both previous status and desired status to help prevent injury and speed recovery post-injury.

The invention relates to a new use of a butyric acid producing beneficial bacterium, in particular to one or more applications of the butyric acid producing beneficial bacterium in preparing a preparation for preventing and treating a severe disease gut barrier injury and post-injury complication, wherein the prevention and treatment of the gut barrier injury and post-injury complication of the severe disease is a prevention an treatment function on the gut barrier which is realized by producing the butyric acid in the intestinal tract, introducing the butyric acid into the intestinal tract, providing intestinal mucosa energy, promoting cell proliferation of the intestinal mucosa, restricting the cell apoptosis of the intestinal mucosa, improving the permeability of the intestinal mucosa and preventing and curing the intestinal mucosa carrier.

The present invention relates to a composition for improving the health status of various joints in the human body. The composition includes at least one plant extract as fatty base with active role, at least one extract from plants with anti-microbial properties, at least one extract from plants with analgesic and/or anti-inflammatory properties, and at least one extract from plants with anti-rheumatic and regenerative properties, to which dimethylsulfoxide, allantoin and/or potassium alum may be added. The composition may be used to treat osteoarthritis, rheumatic joint disease, joint swelling, pain, hallux valgus, traumatic conditions of the joints including sprains, strains, post-surgical recovery, bone edema, and speed up the recovery of athletes post-injury.

This invention discloses a therapeutic post-injury pressure glove and a method to produce the same. The pressure glove is configured to apply pressure onto a plurality of pressure-receiving regions of an injured hand such that each pressure-receiving region receives a pressure within an upper bound and a lower bound determined therefor. In one embodiment, the pressure glove comprises a plurality of custom pressure-applying fabric portions each of which is configured to direct a pressure onto one of the pressure-receiving regions. A suitable fabric specific for each fabric portion is selected so that adequate pressure is provided on a wounded area while maintaining a low pressure on an intact part of the hand. The pressure glove is fabricated with a size less than the hand's size by a reduction factor. The reduction factor and the set of selected fabrics are determined via obtaining a computed pressure distribution.

Belonging to the pharmaceutical field, the invention relates to application of nicotinamide phosphoribosyltransferase (NAMPT) in preparation of neuroprotective and rehabilitation drugs. Experiments of the invention show that NAMPT recombinant protein can penetrate the blood-brain barrier to significantly reduce the volume of ischemic brain injury and alleviate white matter injury after ischemic brain injury; the NAMPT recombinant protein can significantly improve long-term behaviors after ischemic brain injury; the NAMPT recombinant protein can raise revascularization related factors to enhance revascularization after brain hypoxia and neuron regeneration after brain hypoxia, and promote post-injury neurologic function reestablishment; and by mediating oligodendrocyte regeneration and alleviating the demyelination effect of local lysolecithin, the NAMPT recombinant protein can promote restoration of white matter after injury and strengthen post-injury neurologic function reestablishment. Results show that the NAMPT recombinant protein plays a long-term neuroprotective role in drugs treating cerebral stroke, traumatic brain injury and multiple sclerosis, and can be used as a neuroprotective drug to treat acute and chronic injury caused by brain stroke.

The present invention relates to the field of sports, performance, and orthopedic braces, and more specifically, sports, performance, and orthopedic braces made for the hamstring. This Hamstring-Assist Device aids in restoring function to the affected muscle during recovery from an injury by mimicking the structural characteristics of the associated muscles.

The invention relates to a protecting and repairing material for a post-injury uterine cavity and a preparation method thereof. The protecting and repairing material for the post-injury uterine cavity, provided by the invention, is prepared from the following raw materials in percentage by weight (based on total weight of the raw materials): 5% to 55% of polyoxyethylene-polyoxypropylene ether block copolymer, 0.1% to 3% of sodium alginate, 1% to 25% of glycerine, 5% to 15% of polyalcohol and the balance of pure water. The protecting and repairing material for the post-injury uterine cavity, provided by the invention, is unique in performance and convenient in use and is a gel material which is good in biocompatibility and is safe, non-toxic and nonirritant; due to unique temperature response performance, the protecting and repairing material can be used for rapidly and comprehensively covering a uterine wound surface in a liquid fluid state and forming a stable gel state under the condition of body temperature, so as to effectively isolate the wound surface and effectively protect the wound surface of surgical operation. The gel material has an extremely high application value in uterine cavity injury protection.

The invention discloses a method for evaluating the influence of the earthquake on the stability and the safety of a side slope. The method can be used for analyzing the stability and the safety of a side slope during and after an earthquake. The method for evaluating the influence of the earthquake on the stability and the safety of the side slope comprises the steps of (1), calculating the earthquake dynamic effect on a side slope structure containing a dam slope based on an ideal elastoplastic model of the rock and earth mass and the finite element method of the earthquake time process to obtain a plastic strain region of the side slope; (2) for the obtained plastic strain region, calculating the seepage field and the stress field of the side slope based on earthquake post-injury parameters, analyzing and analyzing the stability of the side slope structure during the variation of the side slope in rainfall, reservoir water level, slope excavation and other induced conditions after the earthquake; (3), comparing the result of the step (2) with that irrespective of the earthquake effect to obtain the influence of the earthquake on the stability and the safety of the side slope.

A method of treating traumatic brain injury (TBI) and other neurological disorders is presented herein. Both conditioned media (CM) containing long non-coding RNAs such as NEAT1 (nuclear enriched abundant transcript 1) and MALAT1 (metastasis associated lung adenocarcinoma transcript 1) as well as human adipose-derived stem cells (hADSCs) themselves (Tx), when administered at least 3 hours post injury, were found to significantly ameliorate motor and cognitive functions in young, but not aged, mice undergoing TBI. Significant reduction in cortical damage and hippocampal cell loss was observed in both Tx and CM groups in young rats, whereas less neuroprotection was detected in the aged rats and mainly in the Tx group but not the CM group, which may in part result from decreased homing of the cells to the spleen.

A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines, and further comprising 1 or more terminal cysteines. The composition is administered in therapeutically effective dosages prophylactic ally as soon as possible post-injury in treating neuronal injury.

The invention relates to the technical field of medical instruments, and discloses a bed body bracket for recovery after ankle injury. The bracket comprises a bed body, a supporting mechanism is arranged at the top of the bed body, the supporting mechanism comprises limiting frames, a supporting plate and a containing plate, the two limiting frames are arranged on the left side and the right sideof the top of the bed body respectively, the containing plate is arranged on the supporting plate, and fastening mechanisms are arranged between the two limiting frames and the bed body. According tothe bed body bracket for recovery after ankle injury, a silica gel protection pad is arranged on the concave inner wall of the containing plate, the silica gel protection pad is contacted with a humanbody, rigid contact between the human body and the containing plate is reduced, and pain and discomfort brought to the human body are also reduced. The containing plate is arranged to be concave, thehuman body habit of an ankle wounded person lying on a bed for rehabilitation is met, the contact position and angle of the wounded ankle part can be properly changed on the containing plate, and theproblem that in the rehabilitation process, the foot posture is not moved for a long time, and consequently blood circulation is poor is solved.

The invention provides a mouse derma damage modeling tool for medical experiment. The mouse derma damage modeling tool comprises a bottom plate and a housing, wherein the housing is fixedly arranged on the outer side surface of the bottom plate; a four-limb fixing mechanism and a trunk fixing mechanism are arranged on the upper surface of the bottom plate; a mounting frame is fixedly arranged on the outer side surface of the housing; a PLC is mounted on the side surface of the mounting frame; and the input end of the PLC is electrically connected with the output end of an external power source. According to the mouse derma damage modeling tool for medical experiment disclosed by the invention, through the four-limb fixing mechanism and the trunk fixing mechanism, a mouse can be conveniently fixed, so that the situation that after being injured, the mouse wallops and is out of control is avoided, the working efficiency is improved, and experimental research is facilitated; besides, a damaging tool is mounted on a sliding rod through a mounting block, so that the damage position can be conveniently regulated through regulating the sliding rod; and a driving motor is driven to rotate,so that derma of different sizes can be cut, the using flexibility is increased, the operation is easy, and the using is convenient.