101 results about "Biomimetic synthesis" patented technology

The invention relates to water-collecting polymer filament imitating the spider silk structure and a preparation method thereof. The preparation method comprises the following steps of: immersing common artificial silks into polymer solution mixed by a good solvent and a poor solvent containing polymer, then horizontally pulling out the artificial silks from the polymer solution along the axial direction of the artificial silks, and further enabling the polymer solution to wrap the surfaces of the artificial silks to form a liquid film; then due to Rayleigh instability, causing that the liquid film of the polymer solution on the surfaces of the artificial silks evolutes (break) into a string of liquid drops hung on the artificial silks; by adjusting the humidity and the temperature of the environment, drying the polymer liquid drops hung on the artificial silks so as to form spindle knots with periodic arrangement and a spindle-shaped structure on the surfaces of the artificial silks; and enabling the spindle knots which are in alignment along the axial direction of the artificial silks to form a coarse structure on the surfaces of the artificial silks, and further obtaining the water collecting polymer silks with the similar spider-silk structure by biomimetic synthesis.

The invention relates to calcium carbonate based artificial material and the synthesizing method. It is characterized in that the method comprises following steps: adding low- molecular weight organic matter into system of calcium chloride and sodium carbonate according to a certain proportion, heating, organic molecule absorning selectively on crystal surface to nanocrystal growth along said crystal surface, so it is thin structure for crystal, assembling the crystal thin structure on three-dimensional orientation under interactive action of organic molecule and extension growth of crystal, getting staged layer structure crystal, and that is mentioned final product. The invention is of great importance for understanding biomineralization process and atificial synthesis for biological mineralising material.

A high orientation layered dihydroxy compound metal oxide (LDHs) film and biomimetic synthesis method. Said film is grown on high molecular base material, whose lattice plane (00I) (or ab plane) being normal to surface of base unit with high orientation, compact and film thickness of 0.5-5 micrometer. Said method contains horizontal suspension setting the molecular base unit with surface sulfonation film base unit in solution containing urea and relative metal salt, controlling anion releasing by controlling ureolysis speed through controlling reaction temperature and time.

The invention relates to a preparation method of lithium vanadium phosphate / carbon nanometer composite mesoporous microspheres as positive electrode material of a lithium ion battery. The preparation method comprises the following steps: preparing hungry green algae cell solution from inexpensive green algae cells; adding vanadium oxalate solution into the hungry green algae cell solution dropwise; adding phosphate source and lithium source to obtain gel; drying to obtain lithium vanadium phosphate precursor; grinding lithium vanadium phosphate precursor; heating at about 450 DEG C in the nitrogen atmosphere; and heating to about 750 DEG C and preserving the temperature to obtain black powdered Li3V2(PO4)3 / C nanometer composite mesoporous microspheres. The lithium vanadium phosphate / carbon nanometer composite mesoporous microspheres prepared by the invention can be used as the positive electrode material of the lithium ion battery, and can be used for preparing portable or power lithium ion battery.

The invention discloses a making method of dielectric-pore silica, which is characterized by the following: adopting organic siloxane as silicon source and nitrate as hydrolytic condensed catalyst of organic siloxane; synthesizing in the CTAB-TEOS-MNO3-H2O under indoor temperature; obtaining the product with IV-typed curve and specific surface area at 500-1600m2 / g and most probable aperture at 2-4nm; fitting for macromolecular original covering and original fixed-carrying domain.

The invention relates to a novel tryptanthrin (indole[2,1-b] quinazoline-6,12-diketone) derivative, a synthetic method and a medicinal application thereof. A general structural formula is as follows (see the description). The novel tryptanthrin derivative is synthesized through biomimetic synthesis, the general chemical structural formula of the novel derivative is shown in Figure 1, wherein in the formula, R,R1,R2,R3 are halogen, nitro, amido, hydroxy, alkyl, alkoxy and aryl, R1is morpholine, piperidine, N-methylpiperidine, N-ethylpiperidine, isonipecotic acid, piperazine, 1-(2-pyridyl) piperazine, dimethylamine, diethylamine, 1-(2-ethoxy) piperazine and 1-(2-furoyl) piperazine, and an o-aminobenzoic acid derivative reacts with an indole quinone derivative in solvents of methylbenzene, methyl alcohol, ethyl alcohol, dichloromethane, isopropanol and the like, so as to prepare the novel tryptanthrin derivative. The novel tryptanthrin derivative which has a good inhibiting effect and a good antibacterial effect on cancer cells is preliminarily screened through an MTT experiment and an antibacterial experiment, and the medicine has pharmacological effects in the aspects of tumor resistance, antibiosis and inflammation diminishing.

The invention discloses a biomimetic synthesis method of a high-activity nanometer bismuth phosphate photocatalyst. According to the technical scheme, the biomimetic synthesis method is characterized by comprising the following steps: (1) dissolving soluble starch into a 1mol / L nitric acid solution, adding bismuth nitrate after evenly agitating, and agitating for 2 hours again so as to obtain a mixed solution, wherein the molar ratio of the soluble starch to bismuth nitrate is (1-4):1; and (2) adding phosphate with molar weight equal to that of bismuth nitrate to the mixed solution prepared in the step (1), agitating for 0.5 hour, adjusting the pH to 1-7 by ammonium hydroxide, agitating for 0.5 hour again, transferring into a hydrothermal reaction kettle to carry out hydrothermal reaction at 150-210 DEG C for 6-24 hours, centrifugally separating, washing, drying in vacuum at 60 DEG C for 4 hours, and then burning at 400-500 DEG C for 2 hours, thereby obtaining the high-activity nanometer bismuth phosphate photocatalyst. The high-activity nanometer bismuth phosphate photocatalyst prepared by the method is a nanometer material and has high photocatalytic activity, which is higher than that of P25 and a bismuth phosphate photocatalyst prepared by a common hydrothermal method.

The embodiment of the invention provides a method for preparing a carbon nanotube film and relates to the liquid crystal panel manufacturing field. Requirements on transmitance and conductivity can be achieved without compounding with ITO, and the technology is simple. The method for preparing the carbon nanotube film comprises the following steps of: cleaning a substrate; immersing the cleaned substrate into a silane coupling agent for surface silanization; placing the substrate which has undergone the surface silanization treatment into a carbon nanotube dispersion liquid for biomimetic synthesis of the carbon nanotube film on the substrate, wherein the carbon nanotube dispersion liquid is obtained by the mixing of a carbon nanotube, a sulfonate-containing polymer, a cellulose polymer solution containing carboxyl groups and a perfluoro cationic surfactant; and removing organic matters from the substrate. The embodiment of the invention is used for the preparation of the carbon nanotube film.

The invention discloses a g-carbon nitride-titanium dioxide-silver nanosheet composite. Arginine is utilized as the inducer to realize mineralization of titanium dioxide, 3, 4-dihydroxyphenylpropionic acid is utilized to reduce Ag<+>; the carbon nitride in the g-carbon nitride-titanium dioxide-silver nanosheet composite is a nanosheet structure, the titanium dioxide nanoparticles grow on the carbon nitride in situ is about 10nm, the Ag nanoparticles are about 5nm, the titanium dioxide is anatase type, and the mass ratio of carbon nitride in the composite is 0.80-0.85. The preparation process includes: mixing and reacting an arginine solution with the suspension of carbon nitride for a period of time; adding the Ti-BALDH solution into the suspension to carry out mixed reaction for a period of time, conducting centrifugal washing, freeze drying and calcination, then carrying out violent stirring reaction with a diHPP solution for half an hour, further adding an AgNO3 solution of certain centration, carrying out room temperature stirring reaction for 24h to obtain the g-carbon nitride-titanium dioxide-silver nanosheet composite catalyst. The method provided by the invention is simple and convenient, the reaction conditions are mild, and the obtained catalyst can effectively degrade dyes under visible light.

The invention relates to a biomimetic synthesis method of an Fe3O4 / Fe / C nano composite battery electrode material. The method comprises the following steps: firstly, preparing active nano cellulose from cheap natural cellulose cotton as a template and a carbon source, and then mixing the active nano cellulose with a FeCl3.6H2O water solution; adding ammonium hydroxide to generate sediments, and carrying out hydro-thermal treatment to form a mixture of a precursor Fe3O4 and the cellulose; and carrying out thermal treatment on the mixture in nitrogen atmosphere, so as to obtain the Fe3O4 / Fe / C nano composite material. The composite material prepared by the method can be used for preparing a power lithium-ion battery as a lithium battery anode material.

The invention relates to a biologically active nano powder and its bionic synthesizing method, which consists of the steps of preparing microemulsion, hydrolyzing, mixing, ageing, demoulding, drying and thermal treatment. The obtained powder contains CaO 36-16 wt%, P2O5 4 wt%, SiO2 60-80 wt%.

The invention belongs to the technical field of nanomaterial and medicinal preparations and discloses a preparation method and application of nanopore silicon dioxide xerogel. An amine high polymer (branched polyethyleneimine) serving as a template is introduced into a silicon dioxide inorganic material which is synthesized under mild conditions has nanopores and is at a xerogel state to obtain the nanopore silicon dioxide xerogel. A model medicine propranolole hydrochloride is loaded into the nanopore silicon dioxide xerogel prepared through biomimetic synthesis according to an in-situ medicine carrying method, the release of the medicine is slowed down obviously, the morphology, specific area and pore size of the material are changed in a smart way due to the salvation modification of methyl alcohol and the release of the medicine can be regulated therefore. The preparation method and application of silicon dioxide nanomaterial are widened and a new thought is provided for a sustained and controlled release drug delivery system in pharmaceutics.

The invention which belongs to the biomimetic synthesis inorganic material field concretely relates to a preparation method of a porous calcium carbonate crystal particle having a nanometer cone microstructure unit. The preparation method comprises the following steps: 1, preparing an organic additive solution with a certain concentration, and putting the organic additive solution into a cleaned container; 2, adjusting the pH value of organic additive solution to 5-13 by an acid solution or an alkali solution under stirring, adding an aqueous calcium salt or calcium hydroxide solution, uniformly stirring, and adding an aqueous carbonate solution to obtain a mixed solution, wherein the molar ratio of the calcium salt or calcium hydroxide to the carbonate is 1:1; 3, carrying out stationary ageing on the mixed solution under dustproof room temperature conditions; and 4, separating, and drying the obtained solid product to obtain the porous calcium carbonate crystal particle having the nanometer cone microstructure unit. The method of the invention has the advantages of simple operation and energy saving. The morphology, the particle size, the specific surface area and the cone microstructure unit dimension of the obtained porous calcium carbonate crystal particle can be regulated through regulating the concentration of the organic additive solution and the stationary ageing time in the invention.

The invention relates to a method for preparing an air purifying fabric by a biomimetic synthesis low-temperature in-site secondary growth process. The method comprises the following steps of: (1) mixing anhydrous alcohol, catalyst, distilled water and acetone, and adding silane to obtain a finishing liquor; (2) immersing the fabric into the finishing liquor, mixing, eluting and drying; (3) immersing the fabric into a pretreatment solution containing dimethyldiallylammonium chloride, PPV and sodium chloride, and drying; (4) adding titanium tetraisopropylate into isopropanol under the stirring condition in the inert atmosphere, adding a stabilizer, stirring, continuously adding the isopropanol, inhibitor and deionized water, stirring, and adding a wetting agent to obtain a sol; (5) immersing the fabric subject to treatment by step (3) in the sol to carry out in-site synthesis, and drying; (6) boiling in boiled water, and drying. The invention has the advantages of simple process and low cost, and is suitable for industrial production; the air purifying effect of the prepared material is good, the damage to fiber is small, and the material has antibacterial effect and no secondary pollution.

The invention belongs to the field of biomimetically synthesized inorganic material, specifically to a preparation method of shape controllable monodisperse barium sulfate crystal particles. The preparation method comprises the steps of: after cleaning a container, preparing a polymer solution which is 0.001g-2g / L in concentration; adjusting pH value of the polymer solution by acidic solution or alkali liquor under agitation to 1-13 and injecting barium salt aqueous solution and sulfate aqueous solution in same molarity with same flow to the polymer solution at the same time; after producing obvious turbid in the polymer aqueous solution, stopping injecting barium salt aqueous solution and sulfate aqueous solution; standing and aging for 5-120 hours in dustproof condition at room temperature; separating and drying to obtain the shape controllable monodisperse barium sulfate crystal particles. The method provided by the invention is simple to operate and can save energy resources. The barium sulfate crystal particles prepared are uniform in grain diameter, controllable in shape and the shape of the particles can be controlled from disc type to microballoon type continuously so that the invention has the potential for large scale production.

The invention discloses a two-type 3-acyl-2, 4-pyrrolidine-diketone compound and an efficient bionic synthesis route. The compound is provided with the structure shown in the formula, wherein R1 is hydrogen or alkyl; R2 is hydrogen or alkyl; and R3 is hydrogen, alkyl, aryl or a heteroatom group containing O and N. The compound has better biological activity and provides a foundation for the development of anti-cancer drugs. The synthesis raw materials are simple and easy to obtain, the synthesis process operation is simple, the stereo-selectivity is better, and the yield is higher.

The invention relates to the technical field of luminescent materials, in particular to application of metal halide perovskite CsPbX3 in photocatalytic biomimetic synthesis, and the long afterglow luminescent property of the metal halide perovskite CsPbX3 is applied to photocatalytic biosynthesis. According to the invention, the long afterglow luminescence time of the metal halide perovskite CsPbX3 is as long as 1 h or more. The long-afterglow luminescence of the metal halide perovskite CsPbX3 is applied to photocatalytic biosynthesis, and the yield of photocatalytic biosynthesis can be increased by long-life photo-induced electrons of the perovskite. The application of the perovskite material in the aspect of energy can be expanded, and new inspiration is brought to the development of artificial photosynthesis. According to the photocatalytic biosynthesis system constructed in the invention, the light quantum yield is as high as 3.24%, and the important value of the long afterglow luminescence property of perovskite to the photocatalytic activity is embodied.

The invention discloses a biomimetic synthesis method of a bismuth vanadate visible-light-driven photocatalyst with different microtopographies. The method comprises the following steps: dissolving 0.125-1 g of gelatin into 50 ml of dilute nitric acid solution with a molar concentration of 1 mol / L; after the gelatin is completely dissolved, adding 1 mmol of a Bi(NO3)3.5H2O solid, stirring for 1 h, adding 1 mmol of NH4VO3 powder, and stirring for 30 min; adjusting the pH value of the obtained solution to be 1-9 by using ammonium hydroxide; after stirring for 40 min, transferring a precursor solution to a hydrothermal reaction kettle with a volume of 80 ml to react for 24 h at a temperature of 120-180 DEG C; after the reaction is completed, taking the obtained product out of the reaction kettle and cooling to room temperature, carrying out centrifugal separation so as to obtain a yellow precipitate, and repeatedly washing the yellow precipitate by using deionized water and anhydrous ethanol; putting the obtained product into a drying oven to dry for 12 h at a temperature of 60 DEG C, so that the bismuth vanadate visible-light-driven photocatalyst with different microtopographies is prepared. According to the invention, synthesis in organic reagents or in mixed solvents of organic reagents and water is avoided, therefore, the biomimetic synthesis method is an environment-friendly synthesis method; the prepared bismuth vanadate visible-light-driven photocatalyst with different microtopographies has a high visible-light catalytic activity.

The invention relates to a micro-emulsion with an aphid alarm pheromone analogue and a preparation method for the micro-emulsion. The micro-emulsion comprises an active compound of the aphid alarm pheromone analogue CAU-1204 and an auxiliary agent which comprises a solvent, a cosolvent, an emulsifier, an anti-freezing agent and water. In specific, the micro-emulsion comprises the following ingredients according to weight percentage: 1-25 percent of the CAU-1204 active compound, 5-30 percent of the organic solvent, 10-25 percent of the cosolvent, 15-30 percent of the emulsifier, 0-5 percent of the anti-freezing agent and the balance of water. The preparation method for the micro-emulsion comprises the following steps of: dissolving the CAU-1204 active compound into the solvent, and adding a certain amount of cosolvent; after the CAU-1204 active compound is completely dissolved, adding and stirring the emulsifier, the anti-freezing agent and the like to obtain homogeneous-phase transparent liquid; and continuously and slowly adding a certain amount of water, and fully stirring the ingredients at the same time, thus obtaining transparent uniform liquid, namely the micro-emulsion for the aphid alarm pheromone analogue CAU-1204. The micro-emulsion, which is a biomimetic synthesis reagent, is high in stability and environment-friendly; the preparation technology is simple; and the micro-emulsion can be independently used or combined with other chemical aphicides.

The invention discloses a biomimetic synthesis method of a bismuth vanadate visible-light photocatalyst having a hierarchical structure, and belongs to the technical field of photocatalysis. The biomimetic synthesis method comprises the steps: (1) dissolving soluble starch in a nitric acid solution with the molar concentration of 1 mol / L, stirring uniformly, then adding bismuth nitrate, and continuing to stir for 2 h to obtain a mixed solution; (2) adding ammonium metavanadate into the mixed solution obtained in the step (1), stirring for 0.5 h, adjusting the pH of the system to 1-10 with aqua ammonia, continuing to stir for 0. 5 h, transferring into a hydrothermal reaction kettle, carrying out a hydrothermal reaction for 24 h at a temperature of 180 DEG C, carrying out centrifugal separation, washing, carrying out vacuum drying at a temperature of 60 DEG C, and thus obtaining the bismuth vanadate visible-light photocatalyst having the hierarchical structure. The synthesis method is simple and easy to implement and friendly to the environment; and the synthesized bismuth vanadate visible-light photocatalyst is uniform in morphology, has the hierarchical structure, and has higher visible-light catalytic activity.

The invention relates to a method for preparing repairing material of antibacterial degradable active nanometer composite bionic tone tissue, comprising the following steps of: A, preparing a calcium-phosphorus solution with calcium chloride, sodium dihydrogen phosphate and the like, and mixing the calcium-phosphorus solution, the minocycline solution and the aqueous solution of gelation; B, carrying out reaction on the mixed solution in a silicone oil reactive bath; C, standing in motionless and ageing at the room temperature; D, centrifugalizing the aged substance to obtain the precipitate;freezing and drying the precipitate to obtain the repairing material for the bionic nanometer composite bionic bone tissue. The method adopts molecular bionic synthesis technology, simulates the process of bone mineralization and takes gelatine with excellent biocompatibility as an organic molecule template that regulates and controls growth of apatite (primary inorganic component of bone tissue)under physiologic condition to carry out biomimetic synthesis of repairing material for organic-inorganic composite bone tissue. Meanwhile, the antibacterial agent minocycline in the process of the growth of apatite crystal is loaded. Therefore, a novel antibacterial repairing material of nanometer composite bionic tone tissue is synthesized.

A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure of Formula (I):or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1-R8 and m, n, r, s, t, and u are as defined herein, is provided. Methods of making such compounds are also disclosed as are methods for the treatment of cancer, various infectious diseases, and abnormal cardiovascular function.

The invention discloses a preparation method of a mineralized keratin biomimetic material, which comprises the following steps: 1) adding a nanoscale keratin powder agent into a sterile simulated bodyfluid environment at the concentration of 0.1-500mg / ml, performing standing for mineralization treatment, collecting, carrying out vacuum freeze drying, and grinding into powder to obtain mineralizedkeratin particles; and 2) resuspending the mineralized keratin particles at a concentration of 0.1-500 mg / ml, injecting the resuspended mineralized keratin particles into a template, and drying the template in an oven to obtain the membranous mineralized keratin biomimetic material. According to the invention, a biomimetic synthesis method is adopted to induce self-mineralization of keratin, andthe mineralized keratin biomimetic material is constructed on the premise of not introducing other protein factors or other biomacromolecules. The practice shows that the biomimetic material can provide an ideal nano mineralized microenvironment for growth and proliferation of the DPSCs so as to promote the growth of the DPSCs, so that an important reference value is provided for feasibility of dental pulp tissue regeneration and repair.

The invention relates to the field of medicine synthesis, and discloses an intermediate or application of a preparation method of the intermediate in total synthesis of morphine derivatives. The asymmetric hydrogenation reaction catalyzed by transition metal and the intramolecular Heck reaction in the process of preparing the intermediate are used as key reactions of total synthesis, and efficient preparation of the morphine derivative, especially representative oxycodone, is realized; wherein the total synthesis method has the advantages of excellent chemical and enantioselectivity, high synthesis efficiency, simple operation and large-scale amplification; meanwhile, the prepared intermediate product (compound 13) can be used for preparing other various morphine derivatives only through simple modification and conversion, and the method has important practical significance in changing the current single industrial production mode of depending on artificial planting, extraction and semi-synthesis of morphine derivative drugs of poppy and guaranteeing supply of morphine drugs.

The invention belongs to the biological bone tissue engineering, and concretely relates to a method for biomimetic synthesis of hydroxyapatite by imidazole-4,5-dicarboxylic acid-modified chitosan. Through biomimetic synthesis, a biomineralization mechanism is introduced into a HAP synthesis process, the imidazole-4,5-dicarboxylic acid-modified chitosan having pH responsiveness is taken as an organic matrix, so that the hydroxyapatite having a specific structure and modified surface is obtained. The hydroxyapatite through biomimetic synthesis is hopeful for increasing the biological activity and mechanical property, and provides a reference for biomimetic synthesis of other biominerals.

The invention discloses a biomimetic synthesis method of a size-controllable prismatic bismuth phosphate photo-catalyst. The biomimetic synthesis method comprises the following steps: (1) dissolving bismuth nitrate pentahydrate into a nitric acid solution of which the molar concentration is 1mol / L, uniformly stirring, adding gelatin, and continuously stirring for 2 hours to obtain a mixed solution; (2) adding sodium dihydrogen phosphate of which the molar quantity is equal to that of bismuth nitrate pentahydrate into the mixed solution obtained in the step (1), stirring for 0.5 hour, regulating the pH value of the system to be 1-7 by using ammonia water, continuously stirring for 0.5 hour, transferring to a hydrothermal reaction kettle, performing hydrothermal reaction for 6-24 hours at 140-210 DEG C, performing centrifugal separation, washing, and performing vacuum drying for 12 hours at 60 DEG C to prepare the prismatic bismuth phosphate photo-catalyst. The biomimetic synthesis method disclosed by the invention can avoid the synthesis in an organic solvent or a mixed solvent of an organic reagent and water, and also can avoid regulating the sizes of particles by using the organic solvent which is harmful to the environment, so that the biomimetic synthesis method is a synthetic method which is low in cost and is environment-friendly.