54results about How to "Potential for mass production" patented technology

The invention belongs to the technical field of single-cell capturing and analysis and in particular relates to an efficient capturing, high-content imaging and whole transcriptome analyzing device and method for a single cell. The device is used for capturing the single cell; the device comprises a polydimethylsiloxane micro-well array chip and a cell culture plate substrate or a cell culture dish substrate; the micro-well array chip is fitted to the cell culture plate substrate or the cell culture dish substrate. The invention provides the device and method, which can be used for simultaneously carrying out single-cell high-throughput imaging analysis, whole transcriptome analysis of the target single cell and deep exploration of heterogeneity between the single cells from a whole transcriptome level of the single cells.

The present invention discloses a filter based on axial direction apodized grating. Input single mode waveguide is connected with the upper end port of the left end of an asymmetrical gradual changing directional coupler through input gradual changing waveguide, and the lower end port of the left end of the asymmetrical gradual changing directional coupler is connected with bending waveguide to realize reflection signal download; and the upper end port of the right end of the asymmetrical gradual changing directional coupler is connected with the left end of an antisymmetrical multimode waveguide grating, and the right end of the antisymmetrical multimode waveguide grating is connected with the output single mode waveguide through output gradual changing waveguide. The separation of grating reflection signals employs the asymmetrical gradual changing directional coupler with large tolerance and small insertion loss to realize download of the grating signals; based on a grating filter, the filter based on axial direction apodized grating is large in tolerance and wide in bandwidth regulation range and cannot be limited by the FSR so as to realize filters with various different bandwidth demands; and moreover, the axial direction position regulation of grating teeth realizes apodization so as to realize a grating filter with large sideband suppression ratio and greatly improve the performance of the grating filter.

The invention discloses a 2*2 optical switch with low loss and low random phase error and an N*N optical switch array. First and second input waveguides are connected with first and second front benttapered waveguides respectively after passing through a first power divider; the front bent tapered waveguides in the two groups of interference arms are sequentially connected with the rear bent tapered waveguides through the front end tapered waveguide, the phase shift waveguide and the rear end tapered waveguide; and the first rear bent tapered waveguide and the second rear bent tapered waveguide are connected with the first output waveguide and the second output waveguide through a second power divider. According to the invention, the low-loss ultra-wideband power divider is obtained in anadiabatic coupling or bending directional coupling mode; the random phase error of the interference arms is reduced by introducing the wide waveguides; and the bent tapered waveguides and the taperedwaveguides are added to further reduce the random phase error of the interference arm, so that the 2*2 optical switch with low loss and low random phase error and the N*N optical switch array are finally realized; and the optical switch has the advantages of simple structure, simple process, excellent performance and the like.

The invention discloses a method for improving the coercive force of a sintered neodymium iron boron magnet. The method comprises the following steps: using a magnetron sputtering technology, and sputtering a rare-earth metal thin film with the thickness of 1 to 8 microns on the surface of a sintered neodymium iron boron magnet blank. A Dy/Tb thin film is formed on the surface of the magnet by using the magnetron sputtering technology, the Dy/Tb enters into a surface layer of Nd2Fe14B crystal particles through grain boundary diffusion seepage, and the anisotropy is strengthened, so that the coercive force of the magnet is greatly improved under the condition of guaranteeing that residual magnetism of the magnet is almost unchanged.

The invention belongs to the field of biomimetically synthesized inorganic material, specifically to a preparation method of shape controllable monodisperse barium sulfate crystal particles. The preparation method comprises the steps of: after cleaning a container, preparing a polymer solution which is 0.001g-2g/L in concentration; adjusting pH value of the polymer solution by acidic solution or alkali liquor under agitation to 1-13 and injecting barium salt aqueous solution and sulfate aqueous solution in same molarity with same flow to the polymer solution at the same time; after producing obvious turbid in the polymer aqueous solution, stopping injecting barium salt aqueous solution and sulfate aqueous solution; standing and aging for 5-120 hours in dustproof condition at room temperature; separating and drying to obtain the shape controllable monodisperse barium sulfate crystal particles. The method provided by the invention is simple to operate and can save energy resources. The barium sulfate crystal particles prepared are uniform in grain diameter, controllable in shape and the shape of the particles can be controlled from disc type to microballoon type continuously so that the invention has the potential for large scale production.

The invention discloses a method for manufacturing a PDMS thin film integrated with a sub-millimeter deep channel. The method can be used for observing a micro living body under cultivation and growth states. A PMMA male mold is used as a PDMS channel duplication mold, flat PMMA adhered by transparent adhesive tapes is used as a thin film thickness control device, the obtained channel depth and the obtained thin film thickness are in a sub-millimeter scale, and the channel is embedded into the surface of the thin film. The PMMA male mold is manufactured by using an armok carving machine, and the bump height can reach the sub-millimeter scale, so that the PDMS channel with the sub-millimeter depth can be duplicated. PMMA of which two sides are adhered by a plurality of layers of transparent adhesive tapes is attached to a flat PMMA male mold, and the height of a cavity formed by the PMMA and the flat PMMA male mold is the height of cushion layers of the transparent adhesive tapes. When PDMS is poured into the cavity, the height is the thickness of the PDMS thin film. The height of the PMMA male mold can be controlled by finishing depth parameter setting in a tool path, and the thickness of the PDMS thin film can be controlled according to the layer number of the adhered transparent adhesive tapes.

The invention relates to a synthesis method of stable isotope 18O labeled nipagin ester. The synthesis method comprises the following steps: taking stable isotope 18O-water as a raw material to reactwith benzoic acid-4-diazosulfate by utilizing different feeding amounts of the 18O-water; carrying out column chromatography silica gel separation to obtain an intermediate product p-hydroxy benzoic acid-18O or p-hydroxy benzoic acid-18O2 respectively; then enabling the intermediate product to be subjected to condensation reaction with a hydroxyl compound under the condition of a catalyst and an organic solvent; finally, separating and purifying to obtain a target product nipagin ester-18O or nipagin ester-18O2. According to the synthesis method provided by the invention, the prepared 18O labeled nipagin ester series product has the advantages that the chemical purity is higher than 98 percent and the abundance of stable isotopes is higher than 95 percent atom 18O; the product can sufficiently meet a mass spectrum detection internal standard substance for detecting content of nipagin ester type preservatives in foods and cosmetics.

The invention relates to a decoquinate liposome and a preparation method and application thereof. The preparation raw materials of the decoquinate liposome comprise the following components in parts by weight of 1 part of decoquinate and 2-20 parts of lecithin. The liposome is good in stability, shows favorable malaria resisting effects in and out of animal bodies, can be used for quickly relieving symptoms of malaria particularly subtertian malaria, and is high in safety. The preparation method is simple and feasible, and the decoquinate liposome has mass production potential.

The invention discloses a method for refining and purifying amorphous boron powder, the method comprises the following steps: carrying out acid medium ball milling, primary water washing, alkaline medium ball milling, secondary water washing and vacuum drying treatment on the amorphous boron powder to obtain the amorphous boron powder with the particle size of less than 1.2 mu m and the purity of more than 95%. According to the ball milling refining and acid/alkali washing purification method, the amorphous boron powder which is sold in the market and produced through a magnesiothermic reduction method can be synchronously refined and purified, the problems that the amorphous boron powder sold in the market is large in particle size and low in purity are solved, and the additional value of the amorphous boron powder is increased. The method provided by the invention has the advantages of short flow, low energy consumption, stable and reliable process and large-scale production potential.

The invention discloses a polarization insensitive waveguide grating filter based on a double-layer structure. The filter comprises a polarization insensitive filter unit, the polarization insensitive filter unit comprises a silicon waveguide apodized grating layer and a silicon nitride waveguide apodized grating layer, the silicon waveguide apodized grating filters TE signals, and the silicon nitride waveguide apodized grating filters TM signals. The polarization insensitive filter unit can be realized by adopting a multi-mode waveguide type filter and also can be realized by adopting a grating auxiliary type filter; according to the filter, simultaneous filtering in a TE mode and a TM mode can be achieved, a grating filter insensitive to polarization is achieved, and the device size can be effectively reduced by half compared with a traditional scheme adopting a polarization rotator. In addition, based on a silicon substrate and a silicon nitride waveguide grating filter, the filter is large in tolerance and small in insertion loss, the adjustment range of the central wavelength is not limited by FSR, and filters with different bandwidths can be achieved by setting different coupling coefficients.

The invention relates to a 3D sea water desalination chip device based on an ion concentration polarization principle. The 3D sea water desalination chip device comprises a base adopting 3D printing and a shell adopting 3D printing, a convexly formed buffer solution channel is formed in the base, and a micro-nano membrane channel, a desalted water channel, a concentrated saline water channel and a water outlet are also formed in the base; after the shell and the base are combined, a saline water channel is formed. After a 3D printing material is adopted for combination, fit is tight, no seam is formed, and leakproofness is extremely good; the base and the shell are clamped, connected and fixed by virtue of a 3D printing surrounding edge, the fixed position is accurate, glue or a nail does not need to be used, the integrity can be guaranteed, and the device can not be destroyed by the glue or nail; the manufacturing cost is low, and the device has mass production potency and is recyclable; the device is supported by 3D printing, so that the precision of the dimensions and shape of the device is not limited by familiarity degree of skills of workers, and the obtained finished product has relatively good dimensions and precision; the ion concentration polarization principle is utilized for carrying out sea water desalination, the energy consumption is low, the desalination efficiency is high, and no harm is done to the environment.

The invention discloses a preparation method for a grating structure color functional surface based on injection shaping. A silicon mother mold with a grating structure is prepared by an ultra-violetlithography machine and an etching machine; electric conduction processing is conducted on the silicon mother mold, a gold film conductive layer is deposited on the surface of the silicon mother mold,the silicon mother mold is then placed in an electroforming liquid as a cathode and connected with a negative electrode of a pulse power source, a conductive nickel plate is taken as an anode and connected to a power source positive electrode, an electroforming technology is started, ultrasonic cleaning is conducted with absolute ethyl alcohol and distilled water, and a nickel mold core of whichthe surface has the grating structure is obtained after drying; and the nickel mold core is installed on an injection molding mold, and then the injection mold is installed to an injection molding machine for injection molding, so that the grating structure color functional surface is obtained. The method is short in forming cycle, and high in production efficiency and has potential in batched manufacture.

The invention provides an anti-dandruff composition, and a preparation method and application thereof. The anti-dandruff composition is prepared from cajeput essential oil, juniperus formosana essential oil, caraway essential oil and a radix et rhizoma rhei palmatae extract. The invention also provides the preparation method of the anti-dandruff composition. The preparation method comprises the following steps: dispersing the rheum palmatum extract in a solvent to obtain a dispersion liquid; mixing the cajeput essential oil, the juniperus formosana essential oil and the caraway seed essential oil to obtain a mixed solution; and adding the mixed solution into the dispersion solution, and stirring to obtain the anti-dandruff composition. The anti-dandruff composition disclosed by the invention has excellent effects of inhibiting growth of pathogenic bacteria and maintaining balance of scalp flora, and can generate anti-inflammatory and itching-relieving effects in cooperation with the effect of inhibiting histamine secretion; all the functional components are natural plant extracts, so that the irritation to a human body is relatively small; and the preparation method is simple and efficient and has wide application value.

The invention discloses a 2D semiconductor heterojunction based AND/OR logic gate circuit and realization and preparation methods thereof. Two 2D semiconductor heterogeneous PN junctions with unidirectional conductivity are connected in parallel and cooperated with a fixed resistor to realize AND/OR logic functions. The grid voltage is changed to adjust the direction of the unidirectional conductivity of the 2D semiconductor heterogeneous PN junctions, so that the PN junction is changed into an NP junction. When the 2D semiconductor heterogeneous PN junctions are in different unidirectional conductivity directions, the AND and OR logic functions can be realized, namely, change between AND and OR logics can be changed by changing the grid voltage. Thus, a preparation technology of the device is simple, the circuit is easy to realize, the circuit area is reduced greatly and large-scale integration can be realized.

The invention discloses a novel efficient chelate antioxidant as well as a preparation method and application thereof, dopamine hydrochloride, sulfate hydrate and a buffer agent are taken as main raw materials, and the specific preparation method comprises the following steps: in a buffer solution, adding a catalyst, the polydopamine chelate antioxidant is prepared through oxidative auto-polymerization of dopamine and chelation reaction of polydopamine and sulfate hydrate. The polydopamine chelate antioxidant is of a macromolecular polymer structure, is not easy to migrate, is well dispersed in a non-polar polyolefin matrix, has an efficient thermal oxidation stabilization effect on a polyolefin material, is simple in synthesis method and has large-scale production potential.

The invention relates to the technical field of new energy materials, in particular to a method for preparing titanium niobium oxide. The method comprises the following steps: S1, adding a niobium source and a titanium source into a solvent; the solvent is alcohol or a mixture of alcohol of which the boiling point is greater than 100 DEG C; the niobium source comprises one or two of niobium oxalate and niobium ammonium oxalate, and the titanium source comprises one or two of titanium isopropoxide and tetrabutyl titanate; s2, concentrating the solution obtained in the step S1 at 100-220 DEG C to form gel; and S3, calcining the gel obtained in the step S2 to obtain the titanium niobium oxide. By screening a titanium source, a niobium source and a solvent, when gel is formed, the temperature is controlled to be 100 DEG C or above, and esterification reaction is carried out in a solution, so that titanium and niobium are uniformly distributed in the gel, and uniform distribution and consistent performance of product particles are facilitated. And the preparation process is carried out under normal pressure, the reaction condition is mild, the repeatability is good, and the potential of large-scale production is achieved.

The invention discloses an intelligent contact lens containing a flexible circuit and a preparation method thereof.The intelligent contact lens comprises a first packaging layer, the flexible circuit, a second packaging layer and a contact lens layer which are sequentially arranged, and the second packaging layer is located on the side, opposite to the eyes, of the contact lens layer; the first packaging layer and the second packaging layer are made of the same material which is an elastomer material. According to the invention, no extra substrate material is introduced, the material adopted by the packaging layer has high stretchability and bendability, and the whole preparation process can be well integrated into the production process of the current contact lenses, and has the potential of large-scale production.

The invention discloses an omni-directional dynamic heat source type uniaxial micro-mechanical accelerometer and a processing method thereof. The accelerometer comprises a sensitive layer, a substrate layer and a cover plate, the sensitive layer comprises a middle heating cavity and a middle detection cavity, and the upper surface of the sensitive layer is provided with an omni-directional oscillator heater and a pair of thermistors; the omni-directional dynamic heat source pendulum heater is suspended at the central position of the sensitive layer through eight completely symmetrical semicircular supporting beams; the heater and the thermistor are electrified in a constant current mode; and a groove is etched on the cover plate and is hermetically connected with the upper surface of the sensitive layer. Measurement of uniaxial acceleration can be realized, the input acceleration on the X axis can be sensed, the measurement range is large, and the impact resistance is high. The accelerometer inherits the advantages of an MEMS sensor, has the advantages of being small in size, light in weight, low in cost and the like, and conforms to the development direction of the sensor towards microminiaturization, integration and intelligence. Meanwhile, the accelerometer has the advantages of simple structure and processing technology, large measuring range, high reliability and the like.