2 results about "Decoquinate" patented technology

The invention relates to a suspension type nano decoquinate premixing agent which is mainly prepared from the following raw materials in parts by weight: 5-15 parts of decoquinate, 15-25 parts of an antioxidant, 5-10 parts of a plasticizer, 2-8 parts of a nucleation inhibitor and 45-70 parts of a carrier material. The defects that decoquinate is difficult to take, poor in palatability, poor in mixing uniformity, difficult to absorb during oral administration, poor in bioavailability and the like are effectively overcome. The suspension type nano decoquinate preparation is prepared through a solid dispersion technology, the taste is masked, the dissolution rate of decoquinate is also possibly improved, the problem that the administration mode is single is solved, nano-scale molecules are prepared through the technology, the oral absorption rate is increased, the effect is quickly achieved, and the bioavailability is improved. And the method has obvious practical value.

This invention provides a water-soluble toltrazuril solid powder, its preparation method, and its application. The water-soluble toltrazuril solid powder is a solid adsorption complex formed by toltrazuril and an adsorption ligand under alkaline conditions. The adsorption ligand is any one of tris(hydroxymethyl)aminomethane, tetrabutylammonium bisulfate, dodecyltrimethylammonium chloride, and N-ethylpiperazine. The molar ratio of toltrazuril to the adsorption ligand in the solid powder is 1:(1.1-1.3). It can dissolve rapidly without stirring under still drinking water conditions, and no drug precipitation occurs after long-term storage after dilution, thus meeting the needs of the aquaculture and pet breeding industries for convenient, stable, and efficient anticoccidial administration programs.