Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating allergic rhinitis and a preparation method thereof.The traditional Chinese medicine composition comprises, by weight, 5-50 parts of rhizoma atractylodis, 5-50 parts of semen brassicae, 5-50 parts of cinnamon, 5-50 parts of cassia twigs, 5-50 parts of rhizoma atractylodis macrocephalae, 5-50 parts of radix peucedani, 5-50 parts of perillaseed, 3-10 parts of asarum, 5-50 parts of schisandra chinensis, 5-50 parts of mulberry bark, 5-50 parts of pulp of dogwood fruit, 5-50 parts of glossy privet fruit and 5-50 parts of white ginseng. And 5-50 parts of tussilago farfara. The traditional Chinese medicine composition provided by the invention is rich in raw materials, simple in production process, stable, reliable and good in curative effect, and is an effective medicine for treating allergic rhinitis.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating allergic rhinitis and a preparation method thereof. Background Art

[0002] Rhinitis is a common disease. It is an inflammation of the nasal mucosa and submucosal tissue. It manifests as congestion or edema. Patients often experience nasal congestion, runny nose, itchy nose, throat discomfort, cough and other symptoms. Currently, the number of people suffering from rhinitis is increasing, and the age of patients is tending to be younger.

[0003] Allergic rhinitis is caused by the nasal mucosa being highly sensitive to certain components in the inhaled air. Its symptoms are very similar to those of a cold, but it can occur multiple times a day; when it is not, it is completely normal. The onset of allergic rhinitis is sometimes closely related to the season. Existing allergic rhinitis treatment drugs are mostly chemical drugs, but these drugs can only temporarily relieve symptoms and cannot fundamentally treat rhinitis.

[0004] Existing methods for treating allergic rhinitis are mainly based on chemical drugs, but these drugs can only temporarily relieve symptoms and cannot fundamentally treat rhinitis. Summary of the invention

[0005] The purpose of the present invention is to overcome the above problems existing in the traditional technology and provide a Chinese medicine composition for treating allergic rhinitis and a preparation method thereof.

[0006] In order to achieve the above technical objectives and the above technical effects, the present invention is implemented through the following technical solutions:

[0007] The invention provides a traditional Chinese medicine composition for treating allergic rhinitis. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 5-50 parts of atractylodes, 5-50 parts of white mustard seeds, 5-50 parts of cinnamon bark, 5-50 parts of cassia twig, 5-50 parts of atractylodes, 5-50 parts of peucedanum peucedanum, 5-50 parts of perilla seeds, 3-10 parts of asarum, 5-50 parts of schisandra chinensis, 5-50 parts of mulberry bark, 5-50 parts of cornus fruit, 5-50 parts of glossy privet fruit, 5-50 parts of white ginseng and 5-50 parts of coltsfoot.

[0008] Furthermore, the above-mentioned traditional Chinese medicine composition for treating allergic rhinitis comprises the following raw materials in parts by weight: 30 parts of Atractylodes lancea, 20 parts of white mustard seeds, 20 parts of cinnamon bark, 25 parts of cassia twig, 25 parts of Atractylodes macrocephala, 20 parts of Peucedanum chinense, 20 parts of Perilla seed, 5 parts of Asarum, 20 parts of Schisandra chinensis, 25 parts of mulberry bark, 25 parts of Cornus officinalis, 25 parts of Ligustrum lucidum, 20 parts of white ginseng, and 20 parts of coltsfoot.

[0009] Furthermore, the above-mentioned traditional Chinese medicine composition for treating allergic rhinitis comprises the following raw materials in parts by weight: 20 parts of Atractylodes lancea, 30 parts of white mustard seeds, 15 parts of cinnamon bark, 30 parts of cassia twig, 10 parts of Atractylodes macrocephala, 20 parts of Peucedanum chinense, 10 parts of Perilla seed, 8 parts of Asarum, 20 parts of Schisandra chinensis, 20 parts of Morus alba, 30 parts of Cornus officinalis, 20 parts of Ligustrum lucidum fruit, 25 parts of white ginseng, and 20 parts of coltsfoot.

[0010] Furthermore, the above-mentioned traditional Chinese medicine composition for treating allergic rhinitis comprises the following raw materials in parts by weight: 40 parts of Atractylodes lancea, 20 parts of white mustard seeds, 10 parts of cinnamon bark, 10 parts of cassia twig, 30 parts of Atractylodes macrocephala, 30 parts of Peucedanum chinense, 10 parts of Perilla seed, 10 parts of Asarum, 10 parts of Schisandra chinensis, 25 parts of mulberry bark, 25 parts of Cornus officinalis, 25 parts of Ligustrum lucidum, 15 parts of white ginseng, and 25 parts of coltsfoot.

[0011] The present invention also provides a method for preparing a Chinese medicine composition for treating allergic rhinitis, comprising the following steps:

[0012] 1) Take the raw materials according to weight, pour them into the medicine boiling container, add cold water, and soak them for 20 to 40 minutes before the first decoction;

[0013] 2) Boil over high heat until the pot boils for 4-6 minutes, then reduce to low heat and continue decocting for 20-40 minutes, and pour out the decoction to collect;

[0014] 3) Slowly add cold water to the medicine decoction container again, boil over high heat until the pot boils, and then boil for 4-6 minutes. Then, reduce the heat to low and continue to boil for 20-40 minutes. Pour out the decoction and collect it;

[0015] 4) The two decoction solutions collected in step 2) and step 3) are combined and mixed to obtain a Chinese medicine composition.

[0016] Furthermore, in step 1), the medicine boiling container is a casserole, an enamelware or a stainless steel pot.

[0017] Furthermore, in step 1) and step 3), water is added until the liquid level is 2 to 3 cm higher than the top surface of the API.

[0018] Furthermore, in step 4), the Chinese medicine composition can be made into decoction, granules, capsules, tablets or pills.

[0019] The beneficial effects of the present invention are:

[0020] Compared with chemical drugs, the Chinese medicine composition provided by the present invention is a pure Chinese medicine formula, which has a significant effect on the symptoms of allergic rhinitis, is safer, and reduces the recurrence rate. The Chinese medicine composition of the present invention has abundant raw materials, simple production process, stable and reliable, good efficacy, and is an effective drug for treating allergic rhinitis. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] The pharmacological properties of the raw materials in the Chinese medicine composition provided by the present invention are analyzed as follows:

[0023] Atractylodes is the dried rhizome of Atractylodes lancea or Atractylodes macrocephala, which belongs to the Asteraceae family. It has the effects of drying dampness and strengthening the spleen, dispelling wind and cold, and improving eyesight.

[0024] White mustard seeds are the dried mature seeds of the cruciferous plant white mustard, which has the effects of warming the lungs, resolving phlegm, promoting qi, dispersing nodules, unblocking meridians and relieving pain.

[0025] Cinnamon is the dried bark of the cinnamon plant of the Lauraceae family. It has the effects of warming the middle and dispelling cold, regulating qi and relieving pain.

[0026] Cinnamon twigs are the dried young branches of the cinnamon bark plant of the Lauraceae family. They have the effects of inducing sweat and relieving muscles, warming and unblocking meridians, assisting yang and transforming qi, and balancing and descending qi.

[0027] Atractylodes macrocephala is the dried rhizome of the Atractylodes macrocephala plant of the Asteraceae family. It has the effects of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis, stopping sweating, and calming the fetus.

[0028] Peucedanum peucedanum is the dried root of the Umbelliferae plant Peucedanum peucedanum, which has the effects of descending qi, resolving phlegm, dispersing wind and clearing heat.

[0029] Perilla seed is the fruit of Perilla, an annual herb of the genus Perilla in the Lamiaceae family. It has the effects of lowering qi and eliminating phlegm, relieving cough and asthma, and moistening the intestines and promoting bowel movements.

[0030] Asarum is the dried root and rhizome of the Aristolochiaceae plants Asarum sieboldii, Asarum sieboldii or Asarum sieboldii. It has the effects of dispelling cold, dispelling wind and relieving pain, opening the orifices, warming the lungs and transforming phlegm.

[0031] Schisandra chinensis is the dried mature fruit of the Magnoliaceae plant Schisandra chinensis. It has the effects of astringing, invigorating Qi and promoting body fluid, and nourishing the kidneys and calming the mind.

[0032] Mulberry bark is the dried root bark of the mulberry plant of the Moraceae family. It has the effects of clearing the lungs and relieving asthma, promoting diuresis and reducing swelling.

[0033] Cornus officinalis is the dried mature pulp of Cornus officinalis, a plant of the genus Cornus in the family Cornaceae. It has the effects of nourishing the liver and kidneys and astringing and firming the body.

[0034] Ligustrum lucidum fruit is the dried mature fruit of Ligustrum lucidum, a plant of the Oleaceae family. It has the effects of nourishing the liver and kidneys, improving eyesight and blackening hair.

[0035] White ginseng is a kind of traditional Chinese medicine made from ginseng through special processing. It has the effects of promoting fluid and quenching thirst, calming the mind and improving intelligence, nourishing the spleen and lungs, replenishing vital energy, and nourishing yin and clearing the lungs.

[0036] Coltsfoot is a perennial herb of the genus Coltsfoot in the Asteraceae family. It has the effects of moistening the lungs, relieving qi, relieving cough and reducing phlegm.

[0037] The relevant specific embodiments of the present invention are as follows:

[0038] Example 1

[0039] The present embodiment provides a traditional Chinese medicine composition for treating allergic rhinitis, comprising the following raw materials in parts by weight: 30g of Atractylodes lancea, 20g of White Mustard Seed, 20g of Cinnamon Bark, 25g of Cinnamon Twig, 25g of Atractylodes macrocephala, 20g of Peucedanum chinense, 20g of Perilla Seed, 5g of Asarum, 20g of Schisandra chinensis, 25g of Morus alba, 25g of Cornus officinalis, 25g of Ligustrum lucidum, 20g of White Ginseng, and 20g of Coltsfoot.

[0040] The preparation steps are as follows:

[0041] 1) Weigh the raw materials according to the ratio, pour into the medicine boiling container, add cold water, and soak for 30 minutes before the first decoction;

[0042] 2) Boil over high heat until the pot boils for 5 minutes, then reduce to low heat and continue decocting for 30 minutes, and pour out the decoction to collect;

[0043] 3) Slowly add cold water to the medicine decoction container again, boil over high heat until the pot boils, then boil for 5 minutes, then turn to low heat and continue to boil for 30 minutes, and pour out the decoction liquid for collection;

[0044] 4) Combine the two collected decoctions and mix well to obtain a decoction.

[0045] Directions: Take 400 ml of the decoction and take it twice, before breakfast and after dinner, with a gap of at least half an hour between meals.

[0046] Example 2

[0047] The present embodiment provides a traditional Chinese medicine composition for treating allergic rhinitis, comprising the following raw materials in parts by weight: 20g of Atractylodes lancea, 30g of White Mustard Seed, 15g of Cinnamon Bark, 30g of Cinnamon Twig, 10g of Atractylodes macrocephala, 20g of Peucedanum chinense, 10g of Perilla Seed, 8g of Asarum, 20g of Schisandra chinensis, 20g of Morus alba, 30g of Cornus officinalis, 20g of Ligustrum lucidum, 25g of White Ginseng, and 20g of Coltsfoot.

[0048] The preparation steps are as follows:

[0049] 1) Weigh the raw materials according to the ratio, pour into the medicine boiling container, add cold water, and soak for 30 minutes before the first decoction;

[0050] 2) Boil over high heat until the pot boils for 5 minutes, then reduce to low heat and continue decocting for 30 minutes, and pour out the decoction to collect;

[0051] 3) Slowly add cold water to the medicine decoction container again, boil over high heat until the pot boils, then boil for 5 minutes, then turn to low heat and continue to boil for 30 minutes, and pour out the decoction liquid for collection;

[0052] 4) Combine the two collected decoctions and mix well to obtain a decoction.

[0053] Directions: Take 400 ml of the decoction and take it twice, before breakfast and after dinner, with a gap of at least half an hour between meals.

[0054] Example 3

[0055] The present embodiment provides a traditional Chinese medicine composition for treating allergic rhinitis, characterized in that it comprises the following raw materials in parts by weight: 40g of Atractylodes lancea, 20g of White Mustard Seed, 10g of Cinnamon Bark, 10g of Cinnamon Twig, 30g of Atractylodes macrocephala, 30g of Peucedanum praeparata, 10g of Perilla Seed, 10g of Asarum, 10g of Schisandra chinensis, 25g of Morus alba, 25g of Cornus officinalis, 25g of Ligustrum lucidum, 15g of White Ginseng, and 25g of Coltsfoot.

[0056] The preparation steps are as follows:

[0057] 1) Weigh the raw materials according to the ratio, pour into the medicine boiling container, add cold water, and soak for 30 minutes before the first decoction;

[0058] 2) Boil over high heat until the pot boils for 5 minutes, then reduce to low heat and continue decocting for 30 minutes, and pour out the decoction to collect;

[0059] 3) Slowly add cold water to the medicine decoction container again, boil over high heat until the pot boils, then boil for 5 minutes, then turn to low heat and continue to boil for 30 minutes, and pour out the decoction liquid for collection;

[0060] 4) Combine the two collected decoctions and mix well to obtain a decoction.

[0061] Directions: Take 400 ml of the decoction and take it twice, before breakfast and after dinner, with a gap of at least half an hour between meals.

[0062] Example 4

[0063] Clinical diagnosis of allergic rhinitis: based on "Clinical Disease Diagnosis and Cure and Improvement Criteria" (Second Edition).

[0064] 1. Diagnostic basis of allergic rhinitis:

[0065] (1) Allergic constitution, history of contact with allergens. It can be divided into perennial and seasonal types.

[0066] Sudden onset, paroxysmal nasal itching, nasal congestion and continuous sneezing, with a large amount of watery secretions. Sometimes accompanied by asthma, urticaria, etc.

[0067] (ii) The nasal cavity and nasal concha mucosa are pale or grayish white, edematous, especially in the middle and lower nasal conchae. Often accompanied by polypoid changes or nasal polyps in the middle nasal concha and middle nasal meatus. There is a large amount of watery or thin viscous secretions in the nasal cavity.

[0068] (iii) A large number of eosinophils can be detected in nasal secretions, and a skin scratch test may show a positive reaction.

[0069] 2. Cure and improvement standards:

[0070] Cure: The attack stopped and nasal function was restored.

[0071] Improvement: Symptoms are relieved and attacks are reduced.

[0072] Ineffective: No symptom changes.

[0073] The number of cases and treatment status are shown in the following table:

[0074] Effective rate = (number of improved cases + number of cured cases) / total number × 100%, cure rate = number of cured cases / total number × 100%.

[0075] The decoction provided in Example 1 was used as a Chinese medicine composition for treating allergic rhinitis. The results are shown in Table 1:

[0076] Table 1

[0077] Total number of subjects (persons) 100 Heal (people) 86 Cure rate (%) 86 Improvement (people) 13 Invalid (person) 2 Effectiveness (%) 98

[0078] As can be seen from the table, the cure rate of using this prescription to treat allergic rhinitis is 86% and the effective rate is 98%.

[0079] And the follow-up survey results during the medication period showed that the subjects did not experience any adverse reactions or toxic side effects during the medication period.

[0080] The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to specific implementation methods. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A Chinese medicine composition for treating allergic rhinitis, characterized in that: The invention comprises the following raw materials in parts by weight: 5-50 parts of atractylodes, 5-50 parts of white mustard seeds, 5-50 parts of cinnamon bark, 5-50 parts of cassia twig, 5-50 parts of atractylodes, 5-50 parts of peucedanum chinense, 5-50 parts of perilla seeds, 3-10 parts of asarum, 5-50 parts of schisandra chinensis, 5-50 parts of mulberry bark, 5-50 parts of cornus fruit, 5-50 parts of glossy privet fruit, 5-50 parts of white ginseng and 5-50 parts of coltsfoot.

2. The Chinese medicine composition for treating allergic rhinitis according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 30 parts of atractylodes, 20 parts of white mustard seeds, 20 parts of cinnamon bark, 25 parts of cassia twig, 25 parts of atractylodes, 20 parts of peucedanum, 20 parts of perilla seeds, 5 parts of asarum, 20 parts of schisandra chinensis, 25 parts of mulberry bark, 25 parts of cornus fruit, 25 parts of glossy privet fruit, 20 parts of white ginseng and 20 parts of coltsfoot.

3. The Chinese medicine composition for treating allergic rhinitis according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 20 parts of atractylodes, 30 parts of white mustard seeds, 15 parts of cinnamon bark, 30 parts of cassia twig, 10 parts of atractylodes, 20 parts of peucedanum, 10 parts of perilla seeds, 8 parts of asarum, 20 parts of schisandra chinensis, 20 parts of mulberry bark, 30 parts of cornus fruit, 20 parts of glossy privet fruit, 25 parts of white ginseng and 20 parts of coltsfoot.

4. The Chinese medicine composition for treating allergic rhinitis according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 40 parts of atractylodes, 20 parts of white mustard seeds, 10 parts of cinnamon bark, 10 parts of cassia twig, 30 parts of atractylodes, 30 parts of peucedanum, 10 parts of perilla seeds, 10 parts of asarum, 10 parts of schisandra chinensis, 25 parts of mulberry bark, 25 parts of cornus fruit, 25 parts of glossy privet fruit, 15 parts of white ginseng and 25 parts of coltsfoot.

5. The method for preparing the Chinese medicine composition for treating allergic rhinitis according to any one of claims 1 to 4, characterized in that: The following steps are involved: 1) Take the raw materials according to weight, pour them into the medicine boiling container, add cold water, and soak them for 20 to 40 minutes before the first decoction; 2) Boil over high heat until the pot boils for 4-6 minutes, then reduce to low heat and continue decocting for 20-40 minutes, and pour out the decoction to collect; 3) Slowly add cold water to the medicine decoction container again, boil over high heat until the pot boils, and then boil for 4 to 6 minutes. Then, reduce the heat to low and continue to boil for 20 to 40 minutes. Pour out the decoction and collect it; 4) The two decoction solutions collected in step 2) and step 3) are combined and mixed to obtain a Chinese medicine composition.

6. The preparation method according to claim 5, characterized in that: In step 1), the medicine boiling container is selected from a casserole, an enamelware or a stainless steel pot.

7. The preparation method according to claim 5, characterized in that: In step 1) and step 3), water is added until the liquid level is 2 to 3 cm higher than the top surface of the API.

8. The preparation method according to claim 5, characterized in that: In step 4), the Chinese medicine composition can be made into decoction, granules, capsules, tablets or pills.