31 results about "Anemone chinensis" patented technology

The invention relates to an adipose-derived stem cell and exosome composition for mucosal inflammation and an application of the adipose-derived stem cell and exosome composition. The composition is composed of a hybrid nano-vesicle and a pulsatilla chinensis exosome compound in a mass ratio of 1: 1. The hybrid nanovesicles are prepared by fusing adipose-derived stem cell exosomes and lipidosome and modifying honey polysaccharide, and the pulsatilla chinensis exosome compound is loaded with interleukin 23 peptidomimetic, polyethylene glycol, black scale quantum dots and camptothecin. The composition has the functions of efficient anti-inflammation, immunoregulation, precise targeting and tissue repair, and meanwhile, the curative effect is enhanced through photo-thermal synergistic treatment. The preparation method comprises the steps of exosome extraction by a density gradient centrifugation method, liposome fusion and surface modification. The composition is suitable for treating mucosal inflammation such as inflammatory bowel disease and oral mucositis, has the advantages of high stability, good biocompatibility and the like, and provides a safe and effective novel treatment strategy for clinic.

The present invention provides a method for constructing a characteristic spectrum of Pulsatilla chinensis medicinal materials, standard decoctions, or traditional Chinese medicine granules, comprising the following steps: preparing a test solution from the Pulsatilla chinensis medicinal materials, standard decoctions, or traditional Chinese medicine granules; and subjecting the test solution to ultra-high performance liquid chromatography analysis. The ultra-high performance liquid chromatography analysis conditions include: mobile phase A being a mixture of acetonitrile and methanol, mobile phase B being an aqueous phosphoric acid solution, and employing gradient elution. The characteristic spectrum constructed by the method described herein is rich in information, highly characteristic, and has good reproducibility.

The invention provides a traditional Chinese medicine composition for treating avian colibacillosis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations, and the preparation method comprises the following steps: mixing 12-15 parts by weight of scutellaria baicalensis, 9-11 parts by weight of coptis chinensis, 3.5-4.5 parts by weight of honeysuckle, 5-7 parts by weight of andrographis paniculata and 5-7 parts by weight of dandelion, crushing, adding an acidic ethanol solution of which the mass is 8-10 times of that of the mixture, extracting, filtering, and concentrating to obtain a filtrate; first compound liquid is obtained; mixing 11-13 parts by weight of kudzuvine root, 10-12 parts by weight of Chinese pulsatilla root, 4-5 parts by weight of Chinese arborvitae twig and leaf, 6-7 parts by weight of Chinese gall and 7-9 parts by weight of echinacea purpurea, crushing, adding an ethanol aqueous solution of which the mass is 8-10 times that of the mixture, extracting, and filtering to obtain a compound liquid II; and respectively carrying out vacuum rotary evaporation on the composite liquid I and the composite liquid II until the relative density is 1.09-1.13, mixing, and carrying out spray drying to obtain the product. The traditional Chinese medicine composition prepared by the invention is high in effect taking speed and remarkable in curative effect when being used for treating chicken and poultry colibacillosis.

The invention discloses a pharmaceutical composition for treating diarrhea of yak calves, and relates to the technical field of biological pharmacy, the pharmaceutical composition is prepared from the following raw materials: coptis chinensis, cortex phellodendri, cortex fraxini, Chinese pulsatilla root, purslane, Chinese yam, poria cocos, bighead atractylodes rhizome and liquorice, various natural traditional Chinese medicinal materials are adopted as the raw materials, and the pharmaceutical composition is safe and free of side effects; and adverse effects on the meat quality of the yak calves and the quality of dairy products are avoided. The invention also discloses a preparation method of the pharmaceutical composition for treating diarrhea of yak calves. The preparation method comprises the following steps: step 1, weighing raw materials; 2, pretreating the raw materials; step 3, adding water for soaking; step 4, first heating reflux extraction; step 5, filtering for the first time; step 6, adding water for the second time and extracting; step 7, filtering for the second time; step 8, concentration treatment; the preparation method is easy to operate, effective components in the raw materials can be extracted to the maximum extent through reasonable extraction and concentration processes, and the curative effect of the pharmaceutical composition is improved.

The invention discloses application of a triterpenoid saponin extract in preparation of a medicine for treating liver cancer, and belongs to the technical field of biomedicine.The Chinese pulsatilla saponin D (SB365) shown in the formula (I) is a novel triterpenoid saponin extract extracted and identified from Chinese pulsatilla roots, is small in toxic and side effect, can induce liver cancer cell apoptosis and has a good proliferation inhibition effect on liver cancer cells; on the other hand, the SB365 can inhibit an HR pathway by inhibiting an AKT / ATM / DDR signal transduction axis and combining RAD51 protein in a targeted manner, so that the sensitivity of oxaliplatin to hepatocellular carcinoma is improved.

The invention relates to the technical field of pharmaceutical preparations, in particular to a Qiqing toxin-vanquishing granular preparation for poultry and a preparation method of the Qiqing toxin-vanquishing granular preparation. The Qiqing toxin-vanquishing granular preparation for poultry is prepared from the following raw materials in parts by mass: 15 to 30 parts of radix scutellariae, 15 to 30 parts of rhizoma polygoni cuspidati, 10 to 20 parts of radix pulsatillae, 10 to 20 parts of radix sophorae flavescentis, 15 to 30 parts of radix isatidis, 10 to 20 parts of rhizoma dryopteris crassirhizomae, 5 to 15 parts of folium isatidis, 10 to 15 parts of hydroxypropyl-beta-cyclodextrin, 0.1 to 1 part of dispersing agent, 1 to 3 parts of compound enzyme preparation, 1 to 3 parts of astragalus polysaccharide and 70 to 100 parts of saccharose. The invention has no toxic or side effect, successfully solves the industrial problems of slow effect and large dosage of the traditional Chinese veterinary medicine, and provides reliable technical support for antibiotic-free breeding.

The invention discloses a laying hen feed and a preparation method thereof, and aims to improve the production performance, intestinal health, feed conversion rate and eggshell quality of laying hens. The feed is prepared from conventional raw materials such as corn, soybean meal, fish meal and the like, Chinese herbal compounds such as Chinese pulsatilla roots, radix scutellariae, berberine and the like, and functional additives such as cello-oligosaccharide, gamma-aminobutyric acid, medical stone and the like. Through the synergistic effect of the traditional Chinese medicine compound and the functional additive, a multi-dimensional intestinal tract protection barrier is constructed; a graded crushing and premixing process is adopted, so that accurate release of nutrients is realized, and the feed conversion rate is increased; chinese herbal compound compatibility activates the production performance of laying hens and improves the laying rate; the composite application of medical stone and zeolite is utilized to optimize the gradient adsorption and slow release of mineral elements. The laying hen feed disclosed by the invention has remarkable effects in the aspects of reducing enteritis morbidity, improving production performance, optimizing feed utilization and eggshell quality and the like, and has a wide application prospect.

A fermented traditional Chinese medicine composite preparation for preventing and treating piglet viral diarrhea is prepared by: fermenting a traditional Chinese medicine composition as a basic raw material with five probiotics followed by mixing with a Dunaliella salina liquid, a PEDV yolk antibody, a whey powder, sodium chloride and glucose. The traditional Chinese medicine composition includes following medicinal materials: 1-30 parts of Pulsatilla chinensis, 1-30 parts of Radix paeoniae alba, 1-10 parts of Coptis chinensis, 1-10 parts of Pueraria lobata, 1-15 parts of Bupleurum chinense, 1-20 parts of fried Atractylodes macrocephala, 1-10 parts of Semen raphani, 1-10 parts of Magnolia officinalis, 1-10 parts of Angelica sinensis, 1-10 parts of Aucklandia lappa, and 1-15 parts of Glycyrrhiza uralensis. The traditional Chinese medicine composition is fermented with the five probiotics based on biological fermentation technologies to achieve traditional Chinese medicine biotransformation through microorganism, alter medicine properties, and achieve enhancing efficacy and detoxification.

The invention discloses a traditional Chinese medicine decoction and intestinal probiotic combined medicine for treating ulcerative colitis. The medicine is prepared by uniformly mixing traditional Chinese medicine decoction and intestinal probiotic liquid, the traditional Chinese medicine decoction is prepared by adding water into pulsatilla chinensis, cortex fraxini, coptis chinensis, radix sophorae flavescentis, hairyvein agrimony, pomegranate rind, purslane, sophora flower and sanguisorba officinalis, soaking at room temperature, decocting with strong fire, then slowly decocting with slow fire, and filtering. The intestinal probiotic liquid is one of clostridium butyricum liquid, lactobacillus plantarum liquid and lactobacillus reuteri liquid or a mixture of two or more than two of the clostridium butyricum liquid, the lactobacillus plantarum liquid and the lactobacillus reuteri liquid in equal volume. The traditional Chinese medicine is rich in raw materials, easy to produce and prepare, convenient to take and good in effect, provides a new medicine for treating ulcerative colitis, opens up a new way for treating ulcerative colitis, and has huge economic and social benefits.

The invention relates to the technical field of feed additives, in particular to a feed additive for preventing and treating diarrhea of livestock and poultry as well as a preparation method and application of the feed additive. The feed additive comprises 10-30 parts of traditional Chinese medicine dry paste powder and 70-90 parts of auxiliary materials, wherein the traditional Chinese medicine dry paste powder comprises a traditional Chinese medicine extract extracted from the following traditional Chinese medicine compositions in parts by weight: 5-15 parts of coptis chinensis, 8-15 parts of Chinese pulsatilla root, 3-8 parts of carbonized sanguisorba root, 5-12 parts of honeysuckle stem, 2-5 parts of corydalis tuber, 3-6 parts of elecampane, 5-10 parts of ash bark, 8-15 parts of humifuse euphorbia herb, 8-15 parts of Chinese yam, 8-15 parts of white hyacinth bean, 3-6 parts of fingered citron, 3-6 parts of fortune eupatorium herb and 3-6 parts of raw liquorice. According to the invention, the unique compatibility theory of traditional Chinese medicines is utilized to form a multi-component synergistic effect, pathogens are not easy to generate drug resistance, the residue is low, the safety is high, the requirements of current mainstream'antibiotic-free breeding 'can be met, diarrhea is prevented and treated through the multi-dimensional effects of checking diarrhea, regulating bacteria, protecting membranes, resisting inflammation and promoting digestion, and the feed has the dual advantages of disease prevention and treatment and green safety.

The invention relates to the technical field of traditional Chinese medicine preparations, and particularly discloses a traditional Chinese medicine composition capable of preventing and treating duck plague, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition capable of preventing and treating duck disease comprises the following raw material components in parts by mass: 5-15 parts of corydalis conspersa, 5-15 parts of garlic, 15-25 parts of wild buckwheat rhizome, 5-10 parts of Chinese pulsatilla root, 5-10 parts of dandelion, 5-10 parts of scutellaria baicalensis, 5-10 parts of fructus forsythiae, 1-5 parts of humifuse euphorbia herb and 1-5 parts of liquorice. The traditional Chinese medicine preparation is prepared by taking the traditional Chinese medicine composition and polysaccharide as main raw materials, the traditional Chinese medicine preparation can be used for rapidly and effectively preventing and treating the duck plague, the preparation method is simple and convenient, the cost is low, and the defects in the prior art are overcome.

The invention relates to the field of feed additives, and aims to provide a traditional Chinese medicine feed additive for preventing respiratory diseases of piglets and application of the traditional Chinese medicine feed additive. The additive takes scutellaria baicalensis and honeysuckle as monarch drugs, pulsatilla chinensis as a ministerial drug, and bighead atractylodes rhizome, radix paeoniae alba, elecampane and pericarpium citri reticulatae as adjuvant drugs; the traditional Chinese medicine composition is specifically prepared from the following raw materials in parts by weight: 170 to 190 parts of radix scutellariae, 170 to 190 parts of flos lonicerae, 140 to 160 parts of radix pulsatillae, 140 to 160 parts of rhizoma atractylodis macrocephalae, 110 to 130 parts of radix paeoniae alba, 110 to 130 parts of radix aucklandiae and 90 to 110 parts of pericarpium citri reticulatae. According to the invention, a compatibility strategy of eliminating evil, strengthening body resistance and treating qi, blood and phlegm is creatively adopted, and a multi-target synergistic effect is adopted to realize the purpose of preventing the respiratory diseases of the piglets, so that the limitation of simply treating the respiratory diseases is broken through. The traditional Chinese medicine composition can improve the structure of respiratory flora of piglets, reduce the abundance of harmful bacteria and enhance the immunity of the organism, so that the occurrence probability of respiratory diseases is effectively reduced.

The invention relates to the technical field of veterinary drugs for livestock and poultry dysentery, and particularly discloses a veterinary drug for treating various livestock and poultry dysentery and a preparation method thereof.The veterinary drug is prepared from, by mass, 40-60 g of Chinese pulsatilla roots, 20-40 g of felwort, 20-40 g of scutellaria baicalensis, 30-50 g of radix paeoniae alba, 40-60 g of angelica sinensis, 20-40 g of radix aucklandiae, 20-40 g of areca catechu slices, 10-30 g of liquorice, 20-40 g of coptis chinensis, 30-50 g of berberis poiretii schneid and 30-50 g of ardisia crispa roots. The veterinary drug solves the problem of unsatisfactory curative effect of the traditional western medicine for treating livestock and poultry dysentery.

The invention relates to a traditional Chinese medicine composition for clearing away heat and toxic materials and cooling blood, a preparation method and application and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine composition for clearing away heat and toxic materials and cooling blood comprises coptis chinensis, pulsatilla chinensis, cortex fraxini, Chinese yam, semen coicis, liquorice, codonopsis pilosula, poria cocos, plantain herb and the like, can be used for treating snake wounds, and effectively relieves snake venom symptoms and promotes body recovery through multiple effects of clearing away heat and toxic materials, relieving swelling and pain and strengthening body resistance to eliminate pathogenic factors; the traditional Chinese medicine can also be used for relieving insomnia and skin allergy symptoms, and has very good curative effects.

The invention relates to the technical field of veterinary drugs, in particular to a veterinary drug composition for preventing and treating coccidiosis and a preparation method thereof.The veterinary drug composition comprises a microbial preparation and a medicinal material composition, and the mass ratio of the microbial preparation to the medicinal material composition is 0.5: 1-1: 1; the medicinal material composition is prepared from the following components in parts by mass: 15 to 20 parts of herba artemisiae annuae; 25 to 30 parts of antifebrile dichroa; 8 to 12 parts of hairyvein agrimony; 2-4 parts of garden burnet; 5 to 10 parts of honeysuckle flower; 5-10 parts of Chinese pulsatilla root; 3-7 parts of coptis chinensis; 8 to 12 parts of radix astragali seu hedysari; 2-5 parts of ganoderma lucidum spore powder; 1 to 3 parts of glycyrrhizic acid; 2 to 5 parts of prebiotics; 0.5 to 2 parts of curcumin; 0.1 part to 0.5 part of vitamin E; 2-5 parts of betel nut; 2 to 5 parts of cortex meliae; the microbial preparation comprises bacillus licheniformis, bacillus subtillis, clostridium butyricum, lactobacillus plantarum and lactobacillus acidophilus. New components with a synergistic effect are introduced, the preparation process is optimized, and the preparation method is more efficient and safer and has good economic benefits.