Lactobacillus plantarum ZJ316, procreant antibiotic peptides, preparation and use thereof

A ZJ316, antimicrobial peptide technology, applied in Lactobacillus plantarum ZJ316, the antimicrobial peptide produced and its preparation and application field, can solve the problems of basic research knowledge to be accumulated, lactic acid bacteria antibacterial peptide research started late, etc., and achieve the effect of high-efficiency bactericidal ability
CN101353633AActive Publication Date: 2009-01-28ZHEJIANG GONGSHANG UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHEJIANG GONGSHANG UNIVERSITY
Publication Date
2009-01-28

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Abstract

The invention provides a lactobacillus plantarum ZJ316 which is separated from excrement of infants and anti-bacterial peptide which is produced by the fermentation of the lactobacillus plantarum ZJ316, namely plantaricin ZJ316, and preparation and application thereof; the plantaricin ZJ316 is a novel lactobacillus anti-bacterial peptide with high efficiency and small molecular; the anti-bacterial peptide has bacteriostatic action of broad spectrum; due to small molecular weight, a lipid bilayer is hard to be crossed so as to form a complex body with small holes to be different from the action mode of nisin; but the anti-bacterial peptide also has sterilizing capacity with high efficiency, is a lantibiotic anti-bacterial peptide with superhigh application and development potential and can be applied to preparing the alternative medicine of feed additives, food preservatives and antibiotic, etc.
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Description

(1) Technical field

[0001] The invention relates to a new strain of Lactobacillus plantarum-Lactobacillus plantarum ZJ316, and an antimicrobial peptide produced by fermentation thereof-plantaricin ZJ316 (plantaricin ZJ316) and its preparation and application. (2) Background technology

[0002] Alexander Fleming's discovery of penicillin in 1928 saved thousands of lives. However, the problem of antibiotic resistance has become increasingly serious in recent years, bringing new dangers to people's lives and health. Research and development of new antibiotics has become very urgent. Researchers are working hard to find suitable antimicrobial peptides to replace antibiotics. Lactic acid bacteria are food-grade micro-organisms (GRAS) recognized by the FDA as safe, and lactic acid bacteria antimicrobial peptides will be researched and developed as natural and safe food preservatives and pharmaceutical products. Lactic acid bacteria antimicrobial peptides have been favored by re...

Claims

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