Preparation method and application of chitosan and/or metal composite of chitosan derivative

A technology of chitosan derivatives and metal complexes, which is applied in the direction of drug combinations, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems that have not been reported in the application, and achieve low metal content , reduce the effect of toxic and side effects
CN101654529AInactive Publication Date: 2010-02-24LIAOCHENG UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
LIAOCHENG UNIV
Publication Date
2010-02-24
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a solid phase synthesis method and a liquid phase synthesis method of chitosan and / or zinc, silver, bismuth and rare earth metal composite of chitosan derivative. The solid phase synthesis comprises the following steps: (1) grinding chitosan and / or chitosan derivative to fine powder; (2) grinding the oxides of zinc and / or silver and / or bismuth and rare earth metal to fine powder of which content is 0.0005-2wt% of the weight of chitosan and / or chitosan derivative; (3) mixing the fine powders obtained in step (1) and step (2) and fully grinding for 1-6h to obtain the chitosan and / or metal composite of chitosan derivative. The product of the preparation method can be used to cure diseases such as female vaginitis, cervicitis, cervical erosion, bedsore, skin ulcer, fireburn, empyrosis, trauma, other dermatitis disease, tinea of feet and hands and the like and can be used to prepare various surgical dressings such as film, sponge, gynecological suppository, adhesivefilm and the like.
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Description

technical field

[0001] The invention relates to the technical fields of chemical industry and medicine, in particular to a preparation method of chitosan and / or chitosan derivative zinc, silver, bismuth and rare earth metal complex powder and its application in the treatment of female vaginitis, cervicitis, cervical Erosion, bed sores, skin ulcers, burns, scalds, wounds, and other skin inflammations, tinea pedis and other pharmaceutical applications, can also be used to prepare various trauma dressings such as films, sponges, gynecological suppositories, films, etc. Background technique

[0002] Since the late nineteenth century, foreign countries have carried out extensive and in-depth research on rare earths in medicine. In 1949, the United Kingdom, Australia, Japan and other countries successively included cerium oxalate into the pharmacopoeia for the treatment of motion sickness and vomiting of pregnancy. After the 1960s, it was discovered that rare earth compounds have...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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