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165results about How to "Strong anti-virus" patented technology

Areca nut brine

The invention relates to self-service areca nut brine. The brine contains lotus leaf products and / or lotus leaf extracts and / or chitosan and derivatives thereof, wherein nuciferine and / or lotus leaf flavones in the lotus leaf extracts have obvious functions of weight losing, fat reducing, bacteria suppressing, virus resisting, detoxifying and oxidation resisting; and the chitosan and derivatives thereof have the functions of controlling cholesterol, suppressing bacteria, preventing and controlling hypertension and adsorbing and discharging heavy metals. The brine has the beneficial effects that not only is the variety of the areca nut brine expanded, but also the special functions of the areca nut brine are added; as the areca nut brine is independently packaged and is isolated from the areca nut semi-finished products, the areca nut product can not suffer from scumming, thus making up for the defects of the existing areca nut products and the deficiency of the brine preparation technology; and consumers can voluntarily select the variety and intake of the brine.
Owner:刘凌

Chinese medicinal preparation for treating infantile upper respiratory tract infection and preparation method thereof

The invention discloses a Chinese medicinal preparation for treating infantile upper respiratory tract infection and a preparation method thereof. The Chinese medicinal preparation comprises the following raw material medicaments: Indian buead, ephedra herb, kudzuvine root, white mustard seed, schizonepeta spike, cicada slough, platycodon root, astragalus, gypsum, mint, tangerine peel, divaricate saposhnikovia root, baical skullcap root and heartleaf houttuynia herb. For infants accompanied by sore throat and antiadoncus, watermelon frost and honeysuckle flower are added into the raw material medicaments; for infants accompanied by pyrexia and high fever, weeping forsythia, indigowoad root and gardenia are added into the raw material medicaments; for infants accompanied by poor appetite and indigestion, charred triplet and chicken's gizzard-membrane are added into the raw material medicaments; and for infants accompanied by cough with excessive phlegm, sessile stemona root and unibract fritillary bulb are added into the raw material medicaments. In the Chinese medicinal preparation, pungent warm is matched with acrid cold to dredge sweat pores and cleanse intrinsic heat; and the intrinsic heat is expelled by aiding with pivoting and elevating, and sour-sweet medicaments are subjected to compatibility to nourish yin, clear yingfen and remove the intrinsic heat. The infantile upper respiratory tract infection is caused by exogenous pathogens and seasonal pathogenic factors due to abnormal changes in temperature, and is easy to produce the intrinsic heat, so heat syndromes are common clinically, and quick defervescence is the main treatment aim. The Chinese medicinal preparation has the strong effects of resisting virus, allaying the fever, resisting inflammation and enhancing organism immunity.
Owner:尚德信

Application of compound to preparation of medicines for treating viral pneumonia

ActiveCN111228275AExcellent antiviral pneumonia effectStrong anti-virusAntiviralsRespiratory disorderPurinePharmacology
The invention discloses an application of a compound to preparation of medicines for treating viral pneumonia, and relates to the technical field of drugs. The technical problem that novel antiviral drugs are deficient in the prior art, can be solved. The compound comprises a purine compound adopting the structure as shown in the formula 1, and / or an anthraquinone derivative adopting the structureas shown in the formula 2. The purine compound adopting the structure as shown in the formula 1, and / or the anthraquinone derivative adopting the structure as shown in the formula 2 both can show predominant effect for resisting viral pneumonia when being separately used or used jointly. Drugs for treating viral pneumonia, are prepared by the compound provided by the invention are more notable inactivity compared with clinical frontline drugs, and are better than drugs of ribavirin, oseltamivir and the like.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV +1

9-[2-(phosphonomethoxy)ethyl] adenine bicycloalkoxide and its preparation

An anti-virus active compound 9 -[2 - (phosphine carboxylmethoxy) ethyl] bicyclic alcohol ester is manufactured by: reacting 9 - [ 2- (phosphine carboxylmethoxy) ethyl ] adenosine purine with 4, 4'- dimethyl-5, 6, 5' 6'- bis(methylenedioxy) - 2 - hydroxymethyl - 2' - methoxycarbonyl biphenyl. This bicyclic alcohol ester could exist as its salt and are a kind white solid. Experiment shows that the compounds have the characteristics of high melting point, low hygroscopicity, photo-stability and thermal-stability, obvious anti-virus effect, protect and well care liver. It's a preferred pharmaceutical for anti-hepatitis virus.
Owner:山东中科泰斗化学有限公司

Novel special plant source insecticidal and bacteriostatic agent for lily

InactiveCN104839252AStrong anti-infectionStrong anti-allergicBiocideFungicidesHouttuyniaPlant Sources
The invention discloses a novel special plant source insecticidal and bacteriostatic agent for lily. The agent comprises the following components in parts by weight: 2 to 5 parts of Chinese yam, 1 to 2 parts of angled bittersweet, 3 to 5 parts of fructus cnidii, 2 to 3 parts of dandelion, 1 to 2 parts of cordate houttuynia, 1 to 2 parts of acanthopanax, 2 to 3 parts of pseudo-ginseng, 6 to 7 parts of garlic, 8 to 10 parts of folium artemisiae argyi and 6 to 10 parts of pericarpium citri reticulatae. Two use patterns of soil mixing and water extraction are adopted. The novel special plant source insecticidal and bacteriostatic agent has good preventive effects on fungus diseases and nematodiasis of the lily, is good in effect, durable in pesticide effect, free of public hazard and residue, green, healthy and efficient, and has great application and population value.
Owner:湖州桑农生态农业有限公司

Traditional Chinese medicine preparation for treating child bronchitis and preparation method thereof

The invention discloses a traditional Chinese medicine preparation for treating child bronchitis. The raw material medicines of the preparation include but are not limited to retinervus luffae fructus, purple perilla, radix puerariae, schizonepeta spike, adenophora stricta, poria cocos, radix astragali, radix stemonae, radix ophiopogonis, cortex lycii, radix scutellariae, fragrant solomonseal rhizome, fructus corni, herba taraxaci, honeysuckle flower, lily, radix isatidis, fructus forsythiae, herba violae, radix asteris, rhizoma belamcandae, folium isatidis, ephedra hair, rhizoma anemarrhenae, herba houttuyniae, radix glycyrrhizae and bamboo juice. The traditional Chinese medicine preparation disclosed by the invention is applied to the tender organism of children, and treats the symptoms of temperature disorder, exogenous evil taking advantage of a weak point, external infection of seasonal pathogen, easy heat transmission and repeated infection; the traditional Chinese medicines with different properties are scientifically matched, and the traditional Chinese medicine preparation has good functions of resisting virus, clearing heat and preventing inflammation and enhancing body immunity; moreover, the traditional Chinese medicine preparation is safe and convenient to use, causes little toxic or side effect, and takes short time in curing; and after cured, the symptoms do not recur easily.
Owner:汕头市橄榄枝制药有限公司

Method for producing glycyrrhizia polysaccharide by utilizing tissue culture method

The invention discloses a method for producing glycyrrhizia polysaccharide by utilizing a tissue culture method. The method comprises the following steps of: (1) culturing and inducing liquorice aseptic seedling; (2) adopting an embryonic axis to induce liquorice callus under the liquorice aseptic seedling; (3) selecting the liquorice callus with high growth speed, loose texture and light yellow color, crushing the liquorice callus with a pair of forceps, transferring the crushed liquorice callus into a liquid culture medium for suspension culture and obtaining liquorice suspension cells; (4) culturing the liquorice suspension cells by using a bubble type reactor; and (5) extracting the glycyrrhizia polysaccharide from the liquorice suspension cells obtained in the step (4) to obtain the glycyrrhizia polysaccharide powder. The glycyrrhizia polysaccharide produced by the suspension cells is higher in content than the wild liquorice, has obvious oxidation resistance, virus resistance, tumor resistance and immunoregulatory activity, and has very strong immunoregulatory and anti-fatigue effects. The method is not limited by seasons or regions, is convenient, is easy to operate, and has a wide development prospect.
Owner:TIANJIN UNIV

Processing method of rhizoma polygonati noodles

The invention relates to a processing method of rhizoma polygonati noodles. The processing method comprises the following steps of: extracting effective components of rhizoma polygonati by using a water boiling method; adding the extracted effective components in indica rice and grinding the mixture into powder; then steaming powder and then sequentially pre-drying, ageing, slitting and drying the powder; and finally, packaging according to the requirement to obtain finished products. The rhizoma polygonati noodles processed by the method has fine and smooth mouth feeling and abundant nutrition, has the functions of regulating blood sugar, reducing blood pressure and regulating blood fat and is especially suitable for diabetic to use for a long term.
Owner:青阳县九华生态食品有限公司

Nicotinic acid-contained curcumin ester derivative and preparation method and application thereof

The invention relates to a nicotinic acid-contained curcumin ester derivative and a preparation method and application thereof. The curcumin has various physiological activities and pharmacological effects, such as the resistance of inflammation, bacterium, tumor, tracheitis and oxidation, blood pressure reduction, neuroprotection, and the like. The compound and salts thereof can be used for preparing medicaments of resisting inflammation, cancers, bacteria and viruses, lowering blood pressure and blood sugar and adjusting blood fat. The compound has the excellent effects of lowering blood fat, blood sugar and blood pressure and resisting cancers, bacteria and viruses, has less toxicity, easy preparation method, convenient industrial production, can satisfy the need of the medical field and has the advantages of high curative effect, low toxicity, and the like.
Owner:NANHUA UNIV

A method for extracting cantharidin with compound enzyme

The invention relates to a method for extracting cantharidin from compound enzyme. The method comprises the following steps of: performing enzymolysis on a mylabris medicinal material with cellulase and pectic enzyme; leaching a hydrolysate with a mixed liquid with the volume ratio of chloroform to absolute ethanol to concentrated hydrochloric acid of (1-2):(1-2):(1-2); performing suction filtration on a leached product in hot state and adding chloroform-absolute ethanol-concentrated hydrochloric acid in the volume ratio of (1-2):(1-2):(1-2) for leaching; combining filtrates obtained in two times and performing rotary steaming; dissolving the obtained solid by using a mixed liquid in the volume ratio of water to chloroform of (1-2):(1-2); extracting a lower layer organic phase and performing rotary steaming on the lower layer organic phase; adding a mixed liquor in the volume ratio of absolute ethanol to petroleum ether of (1-2):(1-2) into the obtained solid for dissolving; and recrystallizing with acetone to obtain cantharidin. Compared with the conventional extraction method, the method has the advantages of high extracting speed, low cost, time saving, labor saving, high extraction rate, lower impurity content, easiness for purification and the like, and is suitable for large-scale industrial production.
Owner:BIOCHEM ENG COLLEGE OF BEIJING UNION UNIV

Novel isoflavone nicotinic acid ester derivatives, preparing method and use thereof

The invention relates to a new ramification containing nicotinic acid isoflavone ester and a preparation method and application thereof. Being proved by pharmacological tests, the new ramification containing nicotinic acid isoflavone ester of the invention has functions of antidiabetics, antiatheroscloresis, decreasing blood pressure, anticancer, calmness and antianxiety, antibiosis and antivirus with different degrees and has relatively small toxicity. Therefore, the new ramification containing nicotinic acid isoflavone ester of the invention and salt thereof can be used for preparing medicines of antidiabetics, antiatheroscloresis, decreasing blood pressure, anticancer, calmness and antianxiety, antibiosis and antivirus; meanwhile, the invention has relatively small toxicity and easy preparation method, is convenient for industrial production and can meet the needs of medicine field. The compound of the invention has the advantages of high curative effect, low toxicity, etc.
Owner:NANHUA UNIV

Extraction of astragalus polysaccharide and molecular modification method thereof

InactiveCN101362805AImprove immunityOptimizing conditions for modificationAntiviralsImmunological disordersSulfate radicalsImmunocompetence
The invention discloses a method for extracting astragalus polysaccharide and modifying molecular, pertaining to the technical field of preparation and structure reform of Chinese medicine polysaccharides. A chlorosulfonic acid-pyridine method is used for modifying sulfating molecular, amount of products and substituting degree of sulfate radical are used as indicators, and reaction temperature, reagent mixture ratio and reaction time serve as factors. An orthogonal test is used for determining a preferential best condition of astragalus polysaccharides chlorosulfonic acid-pyridine method that the reaction temperature is 95 DEG C, the mixture ratio of chlorosulfonic acid and pyridine is 1:6 and the reaction time is 1h. Astragalus decoction is slowly added into ethanol for the first time till the final concentration is up to 50 percent, and sediment is removed; supernatant fluid is added into the ethanol till the final concentration is up 60 percent and sediment is taken to obtain crude polysaccharide. After purification, the astragalus polysaccharide is modified by an optimized condition. Through a series of comparisons between antivirus and strengthening immunocompetence, the astragalus polysaccharide has the strongest antivirus and strengthening immunocompetence by purification and sulfating modification.
Owner:NANJING AGRICULTURAL UNIVERSITY

Health care antilipemic tea in bags and method of producing the same

The invention discloses a health tea bag with blood lipid reducing effect and a preparation method thereof. The tea bag is prepared from (by weight part) Gynostemma pentaphyllum 290-310, Polygonum cuspidatum 140-160, Alisma orientalis 190-210, Nelumbo nucifera leaf 140-160, and green tea 190-210. The preparation method comprises selecting raw materials, removing impurities, sterilizing, drying, mixing, grinding into 60 mesh fine powder, and subpackaging into tea bags (each tea bag 8 g) with special filter paper for tea bag. The inventive tea bag has good blood lipid reducing effect, and has the advantages of quick action, no adverse effects, and good economical and practical performance.
Owner:刘湘秋

Method for preparing microbe secondary fermented fodder

The present invention relates to a preparation method of microbial secondary fermented feed for fowls. Said method includes: adding yeast juice, fermented lactobacillus liquor, bay bacillus liquor and animal lactobacillus bifidus liquor into brown sugar liquor, mixing them to obtain first fermented liquor, mixing husk, bran and broken corn, and mixing them with first fermented liquor, making anaerobic fermentation to obtain first fermented feed; mixing first fermented feed with soybean cake, bran fish powder, bone powder, shell powder and edible salt to obtain mixed feed; adding first fermented liquor and ray fungus liquor, hay bacillus liquor and bacillus liquor into brown sugar liquor, mixing them to obtain secondary fermented liquor, mixing the above-mentioned mixed feed and secondary fermented liquor so as to obtain the invented secondary fermented feed for fowls.
Owner:航头品尚特种养殖服务社 +1

Antiviral honeysuckle flower Chinese medicine compound preparation and preparation technique

The invention discloses an anti-virus honeysuckle flower traditional Chinese medicine compound preparation, which is prepared by honeysuckle flower extract, liquoric root extract and baical skullcap root extract; the formula is a pure traditional Chinese medicine preparation and has significant effects of anti-virus, anti-bacterium, eliminating heat, relieving pain, anti-inflammatory and eliminating phlegm and is used for treating the symptoms such as fever, cough, asthma, sore throat, dry mouth and so on caused by exogenous wind-heat and interior stagnancy of toxic heat. The anti-virus honeysuckle flower traditional Chinese medicine compound preparation can also be used for the clinical treatment of upper respiratory tract infection, acute and chronic tonsillitis, pneumonia and laryngitis with the symptoms, the clinical symptoms can disappear rapidly and the efficacy is significant.
Owner:吉林省通化振国药业有限公司

Traditional Chinese medicine compound preparations for treating respiratory disease and method for preparing the same

The present invention relates to one kind of compound Chinese medicine preparation for treating respiratory diseases and its preparation process. The compound Chinese medicine preparation is prepared with the materials including areca, official magnolia bark, tsaoko nut, anemarrhena, white peony root, skullcap root and licorice, and through distilling or supercritically extracting tsaoko nut to obtain volatile oil, extracting official magnolia bark with alcohol and concentrating and drying the extract, decocting the other Chinese medicinal materials and purifying the extract, mixing the extracts and the volatile oil, and further treatment to obtain the compound Chinese medicine preparation in different forms. The compound Chinese medicine preparation has the functions of clearing away heat, expelling surficial evil, relieving cough, resisting inflammation, resisting virus, etc. and possesses high curative effect, high bioavailability and other advantages.
Owner:TIANJIN INSTITUTE OF PHARMA RESEARCH

Lotus leaf jelly

The invention discloses lotus leaf fruit jelly containing edible glue, a sweet agent and edible flavoring essence. The lotus leaf fruit jelly also contains lotus leaf extract comprising nuciferine and lotus leaf flavone. The lotus leaf fruit jelly comprises the following components by weight percentage: 0.01 to 0.05 weight percent of nuciferine, 0.05 to 0.5 weight percent of lotus leaf flavone, 0.6 to 1.2 weight percent of edible glue, 0.04 to 16 weight percent of sweet agent, 0.07 to 0.10 weight percent of edible flavoring essence, and the balance being water. The nuciferine and the lotus leaf flavone have remarkable functions of weight losing, blood fat reduction, bacteriostasis, antivirus, detoxication and oxidation resistance. Not less than 10g of the lotus leaf fruit jelly for everyday has obvious effects of reducing blood fat, losing weight, promoting the urination and relaxing the bowels, and removing intestine toxin. For long-time taking, the lotus leaf fruit jelly can resist ageing and can not cause impacts like excretion burden due to excessive taking.
Owner:NINGBO UNIV

Feed mainly prepared from ginkgo biloba leaves

The invention relates to a feed mainly prepared from ginkgo biloba leaves, which is prepared by crushing and mixing the ginkgo biloba leaves, garlic, ginger, liqoric root, tea leaves, dandelion, almond, yam, spanishneedles herb, willow leaves and honeysuckle in a proportion. The feed adopts a pure Chinese medicinal formula, has good functions of bacteriostasis, antivirus, growth promotion and heat stress resistance, prevents and controls various diseases of livestock, greatly improves the survival rate of young livestock, is safe and nontoxic, has no medicament resistance or antibiotic residue, and greatly improves meat quality of the livestock; and the meat of the livestock is rich in medicinal components beneficial to the health of human bodies, and is more delicious than that of poultry fed by a common feed.
Owner:王敏

Method for planting hybridization soybeans

The invention relates to a method for planting hybridization soybeans, in particular to a method for planting the hybridization soybeans. The method for planting the hybridization soybeans does not need transgene, only adopts wild beans and common soybeans to carry out hybridization for many times, and then carries out seed separation, finally the yield of soybeans planted is high, the soybeans planted through hybridization by the method do not generate shrunken pods as the soybeans are inherited with the genes of the wild beans, the yield is enhanced, the hybridization soybeans have strong virus resistance and disease and insect injury resistance, drought defying and waterlogging resistance and are suitable for growing in various environments, the bean granules of the soybeans contain many plant proteins and abundant plant fat, and the soybeans are especially suitable for the requirement of a human body.
Owner:孟庆林 +1

Chinese medicine as well as preparation method and application thereof

The invention belongs to the traditional Chinese pharmaceutics field and discloses a TCM compound and the preparation method and application. The TCM compound is prepared by the following raw materials according to the weight proportion: periostracum cicadae 400 to 450 parts, baikal skullcap root 200 to 250 parts, earthworm 250 to 300 parts, batryticated silkworm 200 to 250 parts, tatarian aster root 250 to 300 parts, stemona root 400 to 450 parts and fruit of medicine terminalia 200 to 250 parts. The invention has obvious bacteriostatic, antiviral, anti inflammatory, antispasmodic functions as well as relieving cough and asthma and reducing airway responsiveness, which is safe and effective and has low cost, thus the invention can be used for preparing the medicine of relieving cough andasthma as well as antivirus.
Owner:JINLING PHARMA

Chinese materia medica preparation for curing high fever and respiratory tract infection of children

The invention discloses a Chinese materia medica preparation for curing high fever and respiratory tract infection of children, and adopts the following raw materials: notopterygium roots, fructus aurantii, roots of kudzu vine, rhizoma atractylodis, schizonepeta spike, periostracum cicada, poria cocos, astragalus mongholicus, radix angelicae, radix ophiopogonis, radices sileris, scutellaria baicalensis, rhizoma nardostachyos, rhizoma kaempferiae, asarum, dogwood, fructus forsythiae and isatis roots. Specific to immature bodies of children, the Chinese materia medica preparation can be used for curing diseases of disordered heat, exogenous pathogenic factors attacking weak bodies, external infection and seasonal pathogenic factors, high heat-transmission diseases and repeated infection, adopts traditional Chinese medicinal materials with different drug properties as well as scientific compatibility of medicines, has stronger antiviral, antipyretic and anti-inflammatory functions, as well as the function of enhancing the body immunity, is safe, little in toxic and side effect, convenient to use, short in curing time and less prone to recurrence after cure.
Owner:CHONGQING XUANNU BIOTECH

Compound essence oil genital care lotion for women

The invention discloses a compound essence oil genital care lotion for women. The lotion is characterized by comprising the following ingredients: 5-20 parts of camomile essence oil, 10-70 parts of eucalyptus essence oil and 10-70 parts of tea essence oil, and also comprising 10-60 parts of finger citron essence oil. The total parts of above ingredients are 100%. The function of each ingredient is exerted, and meanwhile, the ingredients have synergic effect, so that the effect of the lotion product is improved. The product is mild, has no irritation and good sterilizing effect, and is suitable for daily genital care. Besides, the product has refreshing smell and elegant fragrance, has pressure-relieving and tranquilizing effects, and is beneficial to maintaining acid-alkali balance in genital meatus.
Owner:李天德

Traditional Chinese medicine composite for treating cerebral apoplexy, preparation method and purpose

The invention discloses traditional Chinese medicine composite for treating cerebral apoplexy, a preparation method and purpose. The traditional Chinese medicine composite is prepared from angelica, root of bidentate achyranthes, ginseng, safflower, musk, ligusticum chuanxiong, teasel root and suberect spatholobus stem. The preparation method includes that sieving angelica, root of bidentate achyranthes, ginseng, ligusticum chuanxiong, teasel root and suberect spatholobus stem to remove impurities, cleaning, drying, cutting into blocks or segments, putting on a crock or a piece of tile, using charcoal fire to heat to dry, respectively crushing into powder, sieving safflower and musk to remove impurities, drying, grinding into powder, weighing according to the weight ratio of each kind of raw material, putting in a vessel, mixing uniformly to prepare into powder, and preparing the powder into oral liquid, capsule, pill or the like according to a normal medical method. The clinic experiment proves that the traditional Chinese medicine composite for treating cerebral apoplexy is capable of effectively detoxifying, purging turbidity, removing the necrotic tissue to grow new tissue, completely eliminating toxin and filthy deposited in the blood and enabling the toxin and filthy to be discharged to the outside along with the body metabolism so as to cure and restore cerebral apoplexy and recreate new vitality to realize recovery after being taken by a cerebral apoplexy patient.
Owner:王金荣

Tilapia mossambica streptococcicosis resistant traditional Chinese herbal medicine preparation and preparation process thereof

The invention discloses a tilapia mossambica streptococcicosis resistant traditional Chinese herbal medicine preparation and a preparation process thereof. The traditional Chinese herbal medicine preparation is prepared from the following raw materials in parts by weight: 10-25 parts of scutellaria baicalensis, 10-25 parts of fructus forsythia, 10-25 parts of rheum officinale and 10-25 parts of dioscorea bulbifer. The preparation process comprises the following steps: weighing the raw material medicines according to formula weights, adding distilled water which is 20 times the total weight ofthe raw material medicines, and performing water bath for three times at 100 DEG C, and concentrating, thereby obtaining the traditional Chinese herbal medicine preparation, wherein the water bath lasts for one hour each time, and the alcohol precipitation concentration is 60%. The traditional Chinese herbal medicine preparation has the functions of clearing heat and removing toxins, preventing bacteria and preventing stress as well as regulating body immunity, the disease resistance of tilapia mossambica can be effectively improved, moreover the traditional Chinese herbal medicine preparationis low in medicine residue, medicine residue standard exceeding can be avoided, and drug resistance of pathogenic bacteria can be avoided; and besides, by adopting the preparation process disclosed by the invention, the contents of effective components of the tilapia mossambica streptococcicosis resistant traditional Chinese herbal medicine preparation can be effectively increased, so that the medicinal effect can be improved, the preparation process is simple, and the cost can be lowered.
Owner:GUANGXI UNIV +1

Preparation method and application of dexamethasone sodium phosphate-sodium alga acid composite slow-release coating

The invention discloses a preparation method and application of a dexamethasone sodium phosphate-sodium alga acid composite slow-release coating. A high polymer material is soaked in a sulfuric acid solution of potassium permanganate to conduct acidizing; then the high polymer material is placed in a polymine solution to obtain an amination embellished surface; and oxidation treatment is carried out on the sodium alga acid by using periodic acid or sodium periodate to enable aldehyde groups to be exposed at the tail end of an alginic acid segment to obtain multi-aldehyde group oxidation sodium alga acid, the dexamethasone sodium phosphate solution is soluble in deionized water, and finally materials of the amination embellished surface is placed in a reaction liquid to obtain the composite coating. The technical scheme is that the dexamethasone sodium phosphate and the sodium alga acid can be fixed on the surface of an extracorporeal circulation pipeline in a surface coating mode and has anti-freezing and anti-inflammatory double activity, external medicines are durable and stable in slow-release performance, the dexamethasone sodium phosphate-sodium alga acid composite slow-release coating can replace vein heparinization in a short period, systemic inflammatory response can be lightened through slow release, and short-period operation requirements in department of cardiac surgery can be met.
Owner:TIANJIN CITY THIRD CENT HOSPITAL

20(S) or 20(R)-dammarane-3 beta,12 beta, 20,25-tetraalcohol derivative, its salt and use thereof

The invention provides a 20(S) / 20(R)-dammarane-3beta, 12beta, 20, 25-tetraol derivative, relative salt and anti-tumor application, belonging to medical technical field, wherein the 20(S) / 20(R)-dammarane-3beta, 12beta, 20, 25-tetraol derivative and relative salt are respresented as below, the 20(S) / 20(R)-dammarane-3beta, 12beta, 20, 25-tetraol derivative and relative salt can be combined with medical acceptable carrier into drug compound, to prepare anti-virus and anti-tumor drugs. The 20(S) / 20(R)-dammarane-3beta, 12beta, 20, 25-tetraol derivative and relative salt have stronger anti-viruse and anti-tumor activity than dammarane-3beta, 12beta, 20, 25-tetraol, which can improve the activity of other anti-virus and anti-tumor drugs and reduce the toxicity.
Owner:SHENYANG PHARMA UNIVERSITY

Duck viral hepatitis resisting astraglus polysaccharide phosphorylated molecular modification method

The invention relates to a duck viral hepatitis (DVH) resisting astraglus polysaccharide phosphorylated molecular modification method, and belongs to the technical field of traditional Chinese veterinary medicine preparation. Different alcohol precipitation parts of astragalus polysaccharides are extracted, effective DVH-resisting astragalus polysaccharide parts are screened out through repeated clinical experiments, and then the optimal conditions for sodium tripolyphosphate-sodium trimetaphosphate method phosphorylated molecular modification of the astragalus polysaccharide effective parts are determined through an orthogonal method as the reaction temperature being 70 DEG C, the reaction time being 4 h and the pH being 8.5. The product obtained through infrared spectroscopic analysis is astragalus polysaccharide phosphate ester, the sugar content of astragalus polysaccharide phosphate ester reaches 36.87%, the phosphate radical content reaches 12.03%, and the yield of the product reaches 130.32%. The DHV-1 infected duct embryo liver cell resisting function and DVH curative effect of phosphate ester of the effective parts of astragalus polysaccharides are better than those of the effective parts of astragalus polysaccharides. The obtained phosphate ester of the effective parts of astragalus polysaccharides has high sugar and phosphate radical content and a high product yield, and a good curative effect on DVH is achieved.
Owner:NANJING AGRICULTURAL UNIVERSITY
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