214 results about "Sodium periodate" patented technology

The invention discloses a preparation method of injectable nano composite hydrogel for relieving osteoarthritis, which comprises the following steps: firstly, synthesizing nano rod-like hydroxyapatite with the length of 150-300 nm and the diameter of 10-15 nm, and the hydroxyapatite is hydrophilic hydroxyapatite doped with strontium and europium ions; the preparation method comprises the following steps: by taking Ca (NO3) 2, Sr (NO3) 2, Eu (NO3) 3 and soluble phosphate as main raw materials, carrying out hydrothermal reaction to prepare strontium and europium ion co-doped hydrophobic hydroxyapatite, dispersing the strontium and europium ion co-doped hydrophobic hydroxyapatite in a Tris-HCl buffer solution, adding tannic acid, stirring, centrifugally collecting precipitate, and drying to obtain strontium and europium ion doped hydrophilic hydroxyapatite; the preparation method comprises the following steps: taking chondroitin sulfate and adipic dihydrazide as main raw materials, stirring, dialyzing, freeze-drying, and dissolving in a buffer solution to obtain the chondroitin sulfate solution grafted with the hydrazide group; the preparation method comprises the following steps: taking hyaluronic acid, 3-aminophenylboronic acid and sodium periodate as main raw materials, stirring, dialyzing, freeze-drying, and dissolving in a buffer solution to obtain the phenylboronic acid group grafted oxidized hyaluronic acid solution; the preparation method comprises the following steps: blending hydrophilic hydroxyapatite doped with strontium and europium ions, a chondroitin sulfate solution grafted with a hydrazide group, an oxidized hyaluronic acid solution grafted with a phenylboronic acid group and a recombinant collagen solution, and stirring to obtain the injectable nano composite hydrogel. The injectable nano composite hydrogel obtained by the invention has good biocompatibility, and a favorable local immune microenvironment can be created to immunomodulate macrophages so as to relieve osteoarthritis and promote subchondral bone repair.

The invention discloses a self-healing injectable photo-crosslinking dual-network hydrogel and a preparation method thereof.The preparation method comprises the steps that silk fibroin is subjected to methacrylation modification through a glycidyl methacrylate solution, then dextran of the silk fibroin is subjected to an oxidation reaction through a sodium periodate solution, oxidized dextran is generated, and the self-healing injectable photo-crosslinking dual-network hydrogel is obtained; the amino group in the modified silk fibroin and the aldehyde group of the oxidized dextran are subjected to a Schiff base cross-linking reaction to form the double-network hydrogel. The hydrogel with the double-network structure prepared by the invention is more compact in structure, so that the hydrogel has a series of excellent performances such as injectability, relatively good adhesion, good mechanical property, self-healing property and slow release property after drug loading while having safety.

The invention discloses an organic wastewater treatment agent and a preparation method thereof, and relates to the field of water treatment materials. When the organic wastewater treatment agent is prepared, nano silicon dioxide sequentially reacts with a silane coupling agent 4140, sodium periodate, p-phenylenediamine and dimethyl phosphite, and modified nano silicon dioxide is prepared; the preparation method comprises the following steps: reacting modified nano silicon dioxide with 2, 4, 6-triformyl phloroglucinol and 2, 4-diamino-6-methoxypyrimidine, so as to prepare functionalized nano silicon dioxide; the preparation method comprises the following steps: reacting microcrystalline cellulose with thionyl chloride, N-(glycidyl)-N-phenyl-ethylene oxide methylamine and thiourea in sequence to prepare modified cellulose; and reacting the modified cellulose with the functionalized nano silicon dioxide to prepare the organic wastewater treatment agent. The organic wastewater treatment agent prepared by the invention has the capabilities of resisting bacteria, adsorbing anionic pollutants, adsorbing cationic pollutants and photocatalytically degrading organic pollutants.

The invention relates to the technical field of hydrogel preparation, in particular to a preparation method of novel biomass hydrogel. The biomass hydrogel prepared by the invention overcomes the problems of poor hygroscopicity and poor recyclability of traditional hydrogel in a low-humidity environment. The cassava starch is oxidized by sodium periodate to prepare dialdehyde starch, so that the hydrophilicity is enhanced; sodium alginate is coated and combined with an epoxy group to covalently bond and fix lithium chloride, so that salt slow release and low-humidity deliquescence are realized; the ink containing the nano carbon material is introduced, so that efficient photo-thermal conversion is realized; meanwhile, after the substances are subjected to three-dimensional crosslinking, a polymer network-shaped gel structure is formed, and gradient drying and rehydration control are combined, so that the porous structure and the mechanical strength are guaranteed. The prepared hydrogel can quickly absorb moisture and efficiently perform photo-thermal evaporation in a low-humidity environment, and is good in recyclability.

The invention discloses a preparation method of an edible pectin film capable of monitoring and prolonging fruit freshness, which comprises the following steps: carrying out oxidation reaction on pectin and sodium periodate, then terminating the reaction and purifying to obtain oxidized pectin; the preparation method comprises the following steps: dissolving oxidized pectin in water, then adding histidine, and carrying out heating reaction at 60-120 DEG C for 1-3 hours to obtain a reaction product with pH-responsive fluorescence characteristics; adding a calcium chloride aqueous solution as a cross-linking agent into the reaction product, simultaneously adding glycerol as a plasticizer, stirring and mixing for 5-15 minutes at the temperature of 50-70 DEG C, and then stirring and mixing for 1.5-2.5 hours at the temperature of 20-30 DEG C to obtain a uniform film forming solution; pouring the film-forming liquid into a film, and drying to obtain an edible pectin film; the invention also provides the edible pectin film prepared by the preparation method. The prepared edible pectin film is mainly used for packaging fruits, and the freshness of the fruits can be visually displayed through fluorescence change while the fruits are kept fresh.

The invention discloses sprayable hydrogel for healing a bacterial infected wound and a preparation method of the sprayable hydrogel. The preparation method comprises the following steps: preparing a g-C3N4 nanosheet by taking melamine as a precursor, and then preparing AuNPs-C3N4 nano-enzyme on the g-C3N4 nanosheet through in-situ reduction of HAuCl4. 3H2O; preparing oxidized hyaluronic acid through a sodium periodate oxidation method; the preparation method comprises the following steps: incubating an AuNPs-C3N4 nano-enzyme solution and a glucose solution, adding a Mn < 2 + >-containing manganese salt solution and a bicarbonate solution, then mixing with an oxidized hyaluronic acid solution to obtain a dispersion liquid, spraying the dispersion liquid and a carboxymethyl chitosan solution in a cross-phase manner, and carrying out a Schiff base reaction to prepare the AuNPs-C3N4 / Glu / Mn < 2 + >-carboxymethyl chitosan-OHA hydrogel. The method is simple in preparation process, and the prepared hydrogel can have excellent in-vitro antibacterial efficiency, good biocompatibility and bacterial adsorbability, and can effectively remove bacteria at wound infection parts and promote wound healing.

The invention discloses a novel dust falling material with strong wettability and high strength and toughness and a preparation method thereof. The novel dust falling material is prepared from the following raw materials in parts by weight: 1-3 parts of pectin, 10-35 parts of acrylamide, 1-2.5 parts of an initiator, 0.06-0.1 part of sodium periodate, 20-60 parts of bentonite, 8-12 parts of a wetting agent and 1000-3000 parts of water. According to the dust suppressant, the remarkable advantages of performance breakthrough, environment friendliness and economic optimization are achieved through the synergistic effect of multiple components, it is measured through experiments that the dust suppressant can form a solidified shell layer with toughness and strength on the surface of a coal sample, and the dust suppressant has the unique double-water-locking mechanism that polymer carboxyl chemical bonding water molecules and bound water physically adsorbed between bentonite layers are combined, so that the dust suppressant has the good dust suppressant effect on the surface of the coal sample. A good water loss rate can be maintained in a high-temperature drought environment, and the dust suppression efficiency can be improved due to the rapid film forming characteristic. A solidified layer with a complete structure is formed after drying, pulverized coal is effectively prevented from loosening, the inhibition rates of PM2.5 and PM10 both exceed 95%, and the efficient and lasting dust suppression effect is achieved.

The invention relates to the technical field of biomedicine, in particular to a preparation method of oxidized sodium hyaluronate. The preparation method of the oxidized sodium hyaluronate comprises the following steps: adding sodium hyaluronate into water, then adding a solution containing sodium periodate to carry out an oxidation reaction, adding ethylene glycol to terminate the reaction, and removing impurities, thereby obtaining the oxidized sodium hyaluronate. The molar ratio of the sodium hyaluronate to the sodium periodate is 1: (0.15-3.6). The method has the advantages of high yield and stable process.

The invention discloses a degradable packaging material and a preparation method thereof, and relates to the field of packaging materials. When the degradable packaging material is prepared, after vermiculite powder is grafted with chloromethyltrimethoxysilane, the vermiculite powder reacts with piperazine, bis (2-chloroethyl) methylphosphonate and ethylenediamine, and modified vermiculite powder is obtained; oxidizing corn starch with sodium periodate to obtain modified corn starch; the preparation method comprises the following steps: reacting polyvinyl alcohol, allyl trimethyl ammonium chloride and 5-allyl mercapto-[1, 3, 4] thiadiazole-2-amine to obtain modified polyvinyl alcohol; and uniformly mixing the modified corn starch, glycerol, modified polyvinyl alcohol, modified vermiculite powder and zinc chloride to obtain the degradable packaging material. The degradable packaging material prepared by the invention has excellent flame retardance, antibacterial property, mechanical property and rapid degradability.

A sprayable hydrogel for wound healing caused by bacterial infection and a preparation method thereof, comprising the steps of preparing g-C3N4 nanosheets with melamine as a precursor, and then in-situ reducing HAuCl4·3H2O on the g-C3N4 nanosheets to prepare AuNPs-C3N4 nanozymes; preparing oxidized hyaluronic acid by a sodium periodate oxidation method; incubating the AuNPs-C3N4 nanozyme solution with a glucose solution and then adding a Mn-containing 2+ The manganese salt solution and bicarbonate solution were then mixed with the oxidized hyaluronic acid solution to obtain a dispersion, and the dispersion was sprayed with the carboxymethyl chitosan solution to produce the AuNPs-C3N4 / Glu / Mn 2+ @Carboxymethyl chitosan-OHA hydrogel. The preparation process of this method is simple, and the prepared hydrogel has excellent in vitro antibacterial efficiency, good biocompatibility and bacterial adsorption, which can effectively remove bacteria from wound infection sites and promote wound healing.

The invention provides a high-barrier nanocellulose-based composite liquid mulching film and a preparation method thereof.The preparation method comprises the steps that sodium periodate is added into a sodium alginate solution for an oxidation reaction, an oxidized sodium alginate solution is obtained, a chitosan solution is added into the oxidized sodium alginate solution, and a composite solution is obtained after uniform mixing; mixing the nanocellulose solution with the composite solution, dropwise adding an ammonia water solution to adjust the pH value, and carrying out a cross-linking reaction to obtain a matrix solution; the preparation method comprises the following steps: dissolving 2-acrylamido-2-methylpropanesulfonic acid and methacryloyloxyethyl trimethyl ammonium chloride in deionized water to obtain a precursor solution, and adding an initiator into the precursor solution for copolymerization to obtain a zwitterionic polymer; adding a zwitterionic polymer into the Na-montmorillonite dispersion liquid for intercalation reaction to obtain modified montmorillonite; and uniformly mixing the matrix solution, the modified montmorillonite, the plasticizer, the rheology modifier and the surfactant, and then carrying out standing curing and vacuum defoaming.

The invention belongs to the technical field of mineral flotation, and particularly relates to a cellulose-based coal slime collecting agent and a preparation method and application thereof. The method comprises the following steps: performing wet grinding on recycled waste paper to obtain a paper pulp solution, stirring until paper pulp fibers are uniformly dispersed, adding excessive lithium chloride and sodium periodate, performing stirring reaction, cleaning and centrifuging to obtain precursor cellulose, performing amino alkylation modification to obtain amino alkyl cellulose, preparing the amino alkyl cellulose into a 20 g / L solution, and performing vacuum drying to obtain the lithium ion battery cathode material. And then uniformly mixing with non-polar hydrocarbon oil according to the volume ratio of 1: 2 to obtain the coal slime collecting agent. The prepared coal slime collecting agent contains the hydrophobic nanocellulose with the large length-diameter ratio, in the flotation process, adhesion of bubbles and minerals can be promoted, diffusion of the bubbles is promoted, and the flotation efficiency and the recovery rate are improved.

The invention relates to the field of rubber, in particular to toughened modified nitrile rubber and a preparation method thereof.Magnesium hydroxide is selected as a flame retardant, nano molybdenum oxide hybridized magnesium hydroxide is prepared with a hydrothermal method and epoxidized with gamma-(2, 3-epoxypropoxy) propyltrimethoxysilane, then epoxy-amino reaction is utilized, and the toughened modified nitrile rubber is obtained. Grafting a vanillin-based phosphorus-nitrogen synergistic flame retardant; the vanillin-based phosphorus-nitrogen synergistic flame retardant is prepared by taking bio-based vanillin as a raw material, firstly synthesizing a phosphorus-containing dialdehyde intermediate serving as a precursor from the bio-based vanillin and phenylphosphonic dichloride, then carrying out condensation reaction on the phosphorus-containing dialdehyde intermediate and cyclic imidization melamine, and then carrying out addition with DOPO (9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide), and the cyclic imidization melamine is prepared from melamine and 1, 2-cyclohexanedicarboxylic anhydride. Cellulose nanocrystals are selected to reinforce and toughen nitrile rubber, a sodium periodate oxidation method is adopted to prepare dihydroformylated cellulose nanocrystals, and then aldehyde group-amino reaction is utilized to graft a vanillin-based phosphorus-nitrogen synergistic flame retardant.

The invention belongs to the technical field of oil-proof coatings, and discloses a starch-based oil-proof coating as well as a preparation method and application thereof. The method comprises the following steps: 1) reacting cassava starch with sodium periodate under the condition that the pH is 2-4, centrifugally washing to be neutral, and drying to obtain dialdehyde starch; 2) dispersing dialdehyde starch in water, and then performing gelatinization treatment to obtain a dialdehyde starch solution; dissolving chitosan in an acetic acid solution to obtain a chitosan solution; and 3) mixing the chitosan solution with the dialdehyde starch solution, adjusting the pH value to be acidic, and reacting to obtain the starch-based oil-proof coating. The method is simple, green and environment-friendly; the prepared coating is safe and biodegradable, has excellent oil-proof performance, and improves the tensile strength and tear strength of the paper.

The invention discloses a responsive dynamic hydrogel preparation method, which comprises: 1, dispersing sodium alginate, carrying out a directional oxidation reaction on the dispersed sodium alginate and a sodium periodate aqueous solution to obtain aldehyde group-containing oxidized sodium alginate, and dissolving the aldehyde group-containing oxidized sodium alginate in a hot solution of polyvinyl alcohol to obtain a precursor mother solution A; 2, dissolving a water-soluble chitosan derivative in deionized water, adding aminophenylboronic acid small molecules, and heating to obtain a precursor mother solution B; 3, uniformly mixing the precursor mother liquor A and the precursor mother liquor B to obtain dynamic hydrogel; the preparation method comprises the following steps: coating a precursor mother solution A on a medical material matrix, and then coating the precursor mother solution B on the medical material matrix. According to the invention, an aldehyde group and an amido group form imine bond cross-linking, and a phenylboronic acid group and vicinal diol form boric acid ester bond cross-linking, so that the prepared hydrogel has rapid gelling ability, pH and ROS responsiveness and proper elastic modulus; after the hydrogel disclosed by the invention is applied to a medical material matrix, the biological responsiveness and the interface mechanical softness of the medical material matrix are improved.

The invention discloses a polyellagic acid nanofiber as well as preparation and application thereof. The invention relates to a preparation method of polyellagic acid nanofibers, which comprises the following step: by taking ellagic acid as a raw material, an alkaline aqueous solution as a solvent and sodium periodate as an oxidizing agent, reacting to prepare the polyellagic acid nanofibers. The method is simple and easy to implement, and the prepared polyellagic acid is in a nanofiber shape, good in water solubility, large in specific surface area and higher in free radical scavenging capacity.

This invention discloses a composite hydrogel based on a polysaccharide-based hybrid dual network, its preparation method, and its applications, belonging to the field of marine polysaccharide technology. Based on the important role of amorphous calcium phosphate, a precursor in biomineral formation, in mineralization, this invention prepares a multifunctional composite hydrogel with wet bonding, antibacterial, and remineralization functions. This composite hydrogel can achieve rapid and convenient repair of enamel demineralization. This invention prepares oxidized sodium alginate via an alcohol-aqueous phase using the sodium periodate method. Sodium alginate reacts with carboxymethyl chitosan and dopamine through a Schiff base reaction to form dynamic imine bonds, thus preparing an in-situ self-crosslinking hydrogel. Simultaneously, amorphous calcium phosphate is introduced for secondary crosslinking, preparing a dense dual-network composite hydrogel. The composite hydrogel prepared by this invention has an interconnected three-dimensional porous structure, stable mechanical properties, and uniformly dispersed amorphous calcium phosphate in the form of nanospheres. The composite hydrogel prepared by this invention provides an integrated strategy with clinical translational potential for orthodontic enamel demineralization, with broad market prospects.

The application belongs to the technical field of soft capsules, and discloses a starch-based soft capsule material and a preparation method thereof. The preparation method comprises the following steps: mixing wheat starch and deionized water, adding a sodium periodate solution to react, so as to obtain dialdehyde starch; reacting the dialdehyde starch with glycidyl methacrylate and triethylamine, so as to obtain grafted modified starch; mixing the grafted modified starch with modified nano-silicon dioxide, and reacting after ultrasonic oscillation, so as to obtain nano-silicon dioxide composite modified starch; mixing the composite modified starch with polyvinyl alcohol and polyvinylpyrrolidone, so as to obtain a film forming solution; and after the film forming solution is cast and dried, hot pressing is performed, so that the starch-based soft capsule material is finally obtained. The starch is subjected to multiple hydrophobic modifications, so that the hydrophilic performance is reduced, and the stability of the soft capsule is improved.

The invention relates to the technical field of battery diaphragms, in particular to a wood fiber composite diaphragm and a preparation method thereof. According to the diaphragm, renewable softwood pulp is used as a basic raw material, after aldehyde groups are introduced through sodium periodate oxidation, tannic acid, zinc acetate and cystamine are utilized to synergistically construct a zinc coordination network functional layer; then, molecular crosslinking with methoxypolyethylene glycol, polyethylene glycol, hexamethylene diisocyanate, gamma-aminopropyltriethoxysilane and nano silicon dioxide is realized under the action of a catalyst; and finally, the paper-making and hot-pressing processes are performed to prepare and mold. The diaphragm is particularly suitable for being applied to high-safety and high-performance aqueous metal zinc batteries, and an innovative technical path is provided for industrialization and green upgrading of zinc ion battery diaphragm materials.

This invention discloses a method for preparing a self-healing, antibacterial dynamic hydrogel and its coating application. The method includes: 1. Reacting konjac glucomannan with sodium periodate to achieve aldehyde functionalization, and mixing it with sodium alginate powder to prepare a precursor polymer solution A; 2. Mixing an acylhydrazide or hydroxylamine small molecule crosslinking agent with an aminoglycoside drug to prepare an amino crosslinking agent solution B, and preparing a calcium salt ionic crosslinking agent solution C; 3. Mixing the three solutions and allowing them to stand to obtain a hydrogel. The application involves coating a hydrogel mixture solution onto a biodegradable metal surface after preparing a polyethyleneimine auxiliary layer and then gelling it. This invention utilizes aldehyde-functionalized oxidized konjac glucomannan and two crosslinking agents to form acylhydrazone, oxime, and imine bond networks, endowing the hydrogel with self-healing, self-responsive, and long-term antibacterial properties. The hydrogel of this invention improves the biocompatibility, antibacterial properties, and stability of biodegradable metal substrates, making it suitable for biodegradable implantation applications.

The invention discloses a method for preparing an ion-imprinted cellulose-based aerogel material for extracting uranium from seawater, comprising the steps of sequentially performing sodium periodate oxidation and polyethyleneimine cross-linking on cellulose nanofibers, followed by freeze drying to obtain CNF-O-P aerogel; then adding the CNF-O-P aerogel to a uranium-containing solution for shaking, then adding epichlorohydrin for reaction, and then eluting uranyl ions to obtain the ion-imprinted CNF aerogel, wherein the mass ratio of epichlorohydrin to the CNF-O-P aerogel is 5. The ion-imprinted cellulose-based aerogel material prepared by the method has high uranium adsorption capacity, fast uranium adsorption speed, excellent mechanical properties, ultra-high binding selectivity, excellent antifouling ability and low economic cost, and the CNF aerogel exhibits excellent comprehensive uranium adsorption performance, greatly improving its application potential in natural seawater.

The present invention relates to a preparation method and application of a cyclodextrin - histidine / lanthanum complex, belonging to the technical field of fluorescence sensors. The preparation method includes: mixing a cyclodextrin - histidine fluorescent molecule with a lanthanum source in a solution and heating for reaction to obtain a cyclodextrin - histidine / lanthanum fluorescent complex; wherein, the preparation method of the cyclodextrin - histidine fluorescent molecule includes: mixing an aldehyde - group cyclodextrin and histidine in an aqueous solution for reaction to obtain; the aldehyde - group cyclodextrin is an aldehyde - group cyclodextrin obtained by pre - oxidizing β - cyclodextrin with sodium periodate. Compared with the prior art, the cyclodextrin - histidine / lanthanum complex prepared by the present invention can directly and highly specifically recognize phosphate ions, realizing highly sensitive detection of phosphate ions, being more suitable for accurate detection of trace pollutants at low concentrations and highly selective detection. In addition, portable detection of phosphate ions can be realized through a visualization technique based on fluorescence images.

The invention relates to the field of hygienic products, provides a bacteriostatic absorption core body and a preparation method thereof, and solves the problems that an existing bacteriostatic absorption core body does not have an anticoagulation function, and Ag < + > is easy to migrate to a human body in a manner of coating and adding Ag < + > or the bacteriostatic effect is relatively poor in a manner of coating and adding Ag < + >. The antibacterial absorption core body comprises a lower non-woven fabric layer, an SAP and modified PET fiber mixture layer, a sizing layer and an upper non-woven fabric layer which are sequentially laminated from bottom to top; wherein the SAP and modified PET fiber mixture layer is obtained by mixing SAP and modified PET fibers and then carrying out negative pressure adsorption, conveying and forming, and the modified PET fibers comprise the following raw materials: acetone, absolute ethyl alcohol, PET fibers, sodium periodate, dopamine hydrochloride, N, N-dimethylformamide, propylene glycol monomethyl ether, a silver ammonia solution, azodiol enamine, hydrochloric acid, N, N-dimethylformamide and deionized water.

The invention belongs to the technical field of radioactive waste treatment, and discloses a ceramic solidified body for synergistically solidifying radioactive iodine and cesium as well as a preparation method and application of the ceramic solidified body. The chemical formula of the ceramic solidified body is (Cs2xBa2-2x) (AgyNa1-y) IO6, x is equal to 0.1-0.9, y is equal to 0.1-0.9, and the ceramic solidified body is prepared by mixing silver iodide, barium hydroxide, sodium periodate and cesium carbonate, carrying out dry pressing molding under 20-60 MPa to obtain a rough blank, sintering at 500-700 DEG C, carrying out cold sintering at 200-300 DEG C, and finally annealing at 500-600 DEG C. The curing amount of iodine in the ceramic cured body is 2.4-20 wt%, the curing amount of cesium is 4-46 wt%, and the ceramic cured body has excellent chemical stability and is suitable for curing radioactive iodine and cesium and long-term geological treatment.

The invention provides a preparation process of a composite peracetic acid endoscope disinfectant, and belongs to the technical field of disinfectants. Comprising the following steps: preparing a peracetic acid solution; preparing a stabilizer; preparing a modified corrosion inhibitor; and preparing the composite peracetic acid endoscope disinfectant. The preparation method comprises the following steps: firstly, adding microcrystalline cellulose into a sodium periodate solution to react to prepare aldehyde cellulose, then aminating the aldehyde cellulose by using an ethylenediamine solution, and finally, functionally modifying the aminated aldehyde cellulose by using asparagine as a modifier to prepare the stabilizer. After the stabilizer is added into the peracetic acid disinfectant, the stabilizer and metal ions can form a stable complex, and the catalytic action of the metal ions on decomposition of peracetic acid is reduced, so that the stability of the peracetic acid is effectively improved, and the validity period of the composite peracetic acid endoscope disinfectant can be prolonged.

The invention relates to the technical field of medical and chemical medicines, in particular to a novel synthesis method of L (-)-threo-3-hydroxyaspartic acid hydrochloride. The preparation method comprises the following steps: by taking cheap and easily available D-phenylglycinol as an initial raw material, firstly protecting amino with Boc anhydride, then oxidizing to obtain N-BOC-D-phenylalanine aldehyde 3, then carrying out Grignard reaction on the N-BOC-D-phenylalanine aldehyde 3 and vinyl magnesium bromide at low temperature to obtain corresponding o-amino alcohol, then reacting the o-amino alcohol with 2, 2-dimethoxypropane at 0 DEG C under the catalytic action of p-toluenesulfonic acid, and finally obtaining the 2, 2-dimethoxypropane. The obtained compound 4 is subjected to Upjohn dihydroxylation reaction and sodium periodate oxidation to obtain corresponding aldehyde, and then the aldehyde is oxidized by potassium permanganate under a weak acidic condition to obtain corresponding carboxylic acid 5. Oxidizing a benzene ring by taking ruthenium trichloride as a catalyst and sodium periodate as a co-oxidant to obtain dicarboxylic acid; and finally, refluxing and deprotecting by using hydrochloric acid to obtain the L (-)-chloro-3-hydroxyaspartic acid hydrochloride.

The invention discloses oxidized sodium alginate / polyvinyl alcohol fluorescent hydrogel capable of rapidly gelling as well as a preparation method and application of the oxidized sodium alginate / polyvinyl alcohol fluorescent hydrogel, and belongs to the technical field of hydrogel preparation. The preparation method provided by the invention comprises the following steps: adding sodium periodate into a sodium alginate aqueous solution for oxidation, dialyzing and drying to obtain oxidized sodium alginate; dissolving oxidized sodium alginate in water, adding aminophenylboronic acid and an activating agent, and reacting to obtain a phenylboronic acid-based oxidized sodium alginate solution; and mixing the phenylboronic acid-based oxidized sodium alginate solution with the polyvinyl alcohol solution, and stirring for 8-20 seconds to obtain the water treatment agent. The preparation method disclosed by the invention is simple and convenient, very rapid in gel forming, low in equipment cost and suitable for large-scale preparation; the prepared hydrogel is excellent in swelling property, and emits blue light under ultraviolet irradiation; meanwhile, the property is stable, the pH response and active oxygen response characteristics are achieved, self-healing can be achieved, and good application prospects are achieved in the fields of tissue repair and fluorescent falsification prevention.

This invention relates to the technical field of organic chromium-free tanning agents, and discloses a method for preparing a sustainable green amphoteric organic chromium-free tanning agent, comprising the following steps: (1) adding corn starch to water, then adding sodium periodate, stirring and reacting in the dark to obtain DCST product; (2) mixing ethylene glycol diglycidyl ether, acetone and tetramethylenediamine, then adding hexahydro-1,3,5-tris(hydroxyethyl)-s-triazine dropwise, maintaining the reaction for a period of time after the addition is complete; after the reaction is complete, distilling under reduced pressure to obtain HHTT-EGDE product; (3) dispersing the HHTT-EGDE product in water to obtain HHTT-EGDE solution; mixing the HHTT-EGDE solution with the DCST product, heating and reacting to obtain organic chromium-free tanning agent. Leather tanned with the organic chromium-free tanning agent of this invention has higher Ts, better mechanical strength, whiteness and antibacterial properties.

The invention relates to the technical field of organic water-soluble fertilizers, in particular to an organic water-soluble fertilizer suitable for crops and a preparation method of the organic water-soluble fertilizer. The preparation method sequentially comprises the following steps: adjusting the pH value of an aqueous solution to 5.3-5.7, adding sodium polyaspartate, carboxyl polyethylene glycol carboxyl and dopamine hydrochloride, carrying out a condensation reaction in the presence of a condensing agent, and obtaining a solution A after the condensation reaction is ended; adding tannic acid, ferric nitrate and citrate, and keeping the pH value to obtain a solution B; adjusting the pH value to 6.6-7.0, adding sodium periodate for oxidation, and introducing taurine, histamine and ascorbic acid to obtain a solution C; and finally, adding carbonate, a large amount of ferric nitrate, zinc-magnesium salt and citrate, adjusting the pH value, and supplementing water to a certain amount to obtain a final product. By constructing a multidentate ligand and dynamic covalent network synergistic system, the long-term stability and anti-interference capability of metal ions are remarkably improved, hydrolytic precipitation is effectively inhibited, the low water-insoluble substance content is maintained, and good storage stability and field yield increasing effect are achieved.

The invention relates to the technical field of preparation of natural polysaccharides for in-vivo implantation, and particularly discloses a preparation method of low-molecular-weight oxidized sodium alginate and application of the low-molecular-weight oxidized sodium alginate as a biological cross-linking agent. The preparation method of the low-molecular-weight oxidized sodium alginate comprises the steps that a sodium alginate solution is prepared, after calcium coagulation acidification and neutralization pretreatment, a sodium periodate solution is added for an oxidation reaction, after the reaction is completed, modified activated carbon is added for adsorption and carbon removal, then the oxidized sodium alginate solution is obtained, and an MOFs structural layer is loaded in the modified activated carbon; dialyzing the oxidized sodium alginate solution, and freeze-drying to obtain purified oxidized sodium alginate; and carrying out gamma irradiation treatment on the purified oxidized sodium alginate to obtain the sodium alginate. The oxidized sodium alginate prepared by the preparation method of the low-molecular-weight oxidized sodium alginate is relatively low in harmful impurity content and relatively high in safety, the molecular weight is about 2000, and the oxidized sodium alginate has excellent cross-linking performance when being used as a biological cross-linking agent for an in-vivo implant material.