Method for preparing micro-nano fiber film by electrostatic spinning method

Abstract

The invention belongs to the technical field of electrostatic spinning and relates to a method for preparing a micro-nano fiber film by an electrostatic spinning method. The method comprises the steps as follows: firstly, mixing polyvinylpyrrolidone powder with absolute ethanol, adding epidermal growth factor, magnetically stirring at room temperature for fully dispersing, and standing to obtain a precursor electrostatic spinning solution for electrostatic spinning; secondly, extracting the prepared electrostatic spinning solution by using a disinfected injection needle tube, and placing a mounted electrostatic spinning device at the periphery of a wound; thirdly, turning on a switch of the electrostatic spinning device for electrostatic spinning, forming a layer of uniform micro-nano fiber film at the wound, taking down the original micro-nano fiber film prepared by electrostatic spinning in 24 hours, and repeating the steps and carrying out electrostatic spinning once by facing to the wound; and deducing the rest by analogy for auxiliary treatment of the wound. According to the method, the process steps are simple, the preparation operation is flexible, the preparation cost is low, the film is good in air permeability, favorable for treating and healing the wound, and environment-friendly.

Description

Technical field: [0001] The invention belongs to the technical field of electrospinning, and relates to the application of a novel portable hand-held electrospinning device, a new process for preparing a fiber film capable of covering injured skin wounds by using electrospinning technology, in particular to an electrospinning process A method for preparing micro-nano fiber film by silk method. Background technique: [0002] At present, burns or skin injuries are common accidental traumas that seriously endanger human health. People are threatened by fires and traffic accidents from nature and humans all the time. Especially with the development of science, People's daily life and production are surrounded by combustible materials. The fire hazard is very serious. Burn patients are often scarred and unrecognizable. In severe cases, they will cause permanent disabilities or even life-threatening; Necrosis, vascular embolism, and poor local blood supply cannot effectively cont...

AI Technical Summary

Problems solved by technology

[0002] At present, burns or skin injuries are common accidental traumas that seriously endanger human health. People are threatened by fires and traffic accidents from nature and humans all the time. Especially with the development of science, People's daily life and production are surrounded by combustible materials. The fire hazard is very serious. Burn patients are often scarred and unrecognizable. In severe cases, they will cause permanent disabilities or even life-threatening; Necrosis, vascular embolism, and poor local blood supply cannot effectively control wound infection, so the dressing and treatment of trauma are particularly important; and the skin wounds of burns, scalds and bruises are often irregular in shape, so it is not easy to use conventional surgical dressings and wounds. Treatment method: At present, except for severe burns and scalds that require surgical treatment, other burns and scalds below the second degree are mostly treated with drugs directly applied to the affected area. 2007,18(4):917-918), gel (Burns,2008,34(6):845-855), ointment (Chinese patent application number: 200510047598.0; 02109439.X), oil (Chinese patent Application number: 01127125.6; Burns, 2009, 35(6): 768-775), varnish (general care, 2010, 8(2): 492-493), etc. These are wounds treated by drugs, but for wounds However, the peripheral protection can not play a good role. Even the existing bandages are difficult to cover various wounds optimally, especially the existing bandages and bandages. For example, the wound has poor air permeability, the scab is too thick and hard and lacks elasticity after the medicine dries, which is not conducive to the recovery of body functions and exercise, and is not conducive to changing the dressing again. The ideal treatment method for burns and scalds should be to wrap a layer around the wound to facilitate The air-permeable layer for wound healing can keep the wound fresh and breathable, reduce the leakage of wound fluid, accelerate wound healing, and help the recovery of body functions