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The pyogenic infection is characterized by a severe kind of local infection which is identified with pus formation that is generally caused by the pyogenic bacteria. The infection is characterized by the flow of pus like material which is in the form of yellow whitish fluid.
Method for predicting outcome of purulent lung disease caused by klebsiellapneumoniae
FIELD: molecular biology.SUBSTANCE: method for predicting a high risk of adverse outcome in a patient with purulent lung disease (PLD) infected with gram-negative bacteria of the Klebsiella pneumoniae species is described. The method involves isolating DNA from peripheral venous blood and determining variants of the AQP4 rs1058424 gene. When the AQP4 rs1058424 AA genotype is detected in a patient with PLD and the presence of signs of Klebsiella pneumoniae infection, a high risk of death is determined.EFFECT: based on the determination of the AQP4 rs1058424 genotype for patients with PLD and identified gram-negative bacteria, it becomes possible to fairly early divide hospitalized patients with purulent infection into high-risk and low-risk groups for a fatal outcome.1 cl, 4 ex
Owner:FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE NAUCHNOE UCHREZHDENIE FEDERALNYJ NAUCHNO KLINICHESKIJ TSENTR REANIMATOLOGII I REABILITOLOGII FNKTS RR