Green coagulation plaster and preparation method thereof

Abstract

The preparation method comprises the following steps: selecting leaves and thin stems of any green-leaf herbal medicine with the effects of clearing heat, removing redness, relieving swelling and pain and activating blood circulation to dissipate stasis, drying and crushing the leaves and thin stems into fine powder, adding several times of water, a small amount of vaseline as a lubricant, sodium alginate as a water condensation thickener and a trace amount of potassium sorbate as a preservative, and uniformly mixing the materials. The green leaf hydrogel paste which is similar to the fresh herbal medicine paste in appearance, superior to the fresh herbal medicine paste in quality and same as the fresh herbal medicine paste in curative effect, is used for external treatment of acute joint sprain, traumatic injury, gout joint swelling and pain, skin furuncle and carbuncle sore, erysipelas, innominate pyogenic infections, poisonous insect stings and the like and can be produced in batches and stored for standby application can be obtained. And the medical plaster is an innovative medical plaster product on the market.

Description

Technical Field

[0001] The invention belongs to the technical field of dressing, relates to dressing, and in particular to a green gel paste dressing which maintains the form and function of crushed fresh green leaf herbs and a preparation method thereof. Background Art

[0002] Mashing fresh green leafy herbs into a paste and applying it externally as a bandage to treat boils, carbuncles, sprains, injuries from falls, ulcers, and insect and snake bites is a traditional Chinese medicine practice. Applying this paste is particularly effective for a variety of closed skin and soft tissue conditions, including redness, swelling, heat, and pain. Because of its tender, sticky texture and rich juice, it resembles a green hydrogel. When applied to the affected area, a large amount of water-soluble chlorophyll is released and absorbed through the skin. This uniquely effective treatment for redness, swelling, heat, and pain in the skin and soft tissues caused by trauma or endogenous conditions is far superior to commercially available topical plasters.

[0003] For example, "Common Folk Herbs in Zhejiang Province" records that "to treat carbuncles, furuncles, and unknown swellings: use equal amounts of fresh plowhead grass and fresh wild chrysanthemum leaves. Mash them together and apply to the affected area, it will have miraculous effects." The Baidu Encyclopedia entry on Plowhead Grass also records that "to treat carbuncle, fresh Plowhead Grass and a small amount of Oxalis were washed and mashed into a paste. The paste was applied topically to treat 30 cases of carbuncle. Generally, for those with localized inflammation and no obvious systemic symptoms, the inflammation would disappear and the patient would be cured after 1-2 application of the medicine. If there were systemic symptoms, the symptoms would also be alleviated or disappear after the application. In more than 80% of the cases, after 1-2 application of the medicine, the top of the sore would rupture due to localized inflammation, revealing a pus head. At this time, the pus head could be removed, the sore could be drained, and then Plowhead Grass could be applied: after the granulation tissue of the sore grew, Plowhead Grass dry powder could be used to spread it, and Vaseline gauze could be applied topically. The dressing should be changed once a day, and it would generally be cured after 2-4 application. 19 cases of traumatic infection were treated by applying Plowhead Grass alone to the affected area, and most of them were cured within 2-3 days." Many Chinese medicine books and magazines also contain or report examples and experiences of applying the green leaves of various plants and grasses, such as "Hibiscus mutabilis leaves, Raspberry, Lobelia chinensis, Rosa rugosa leaves, and Bitter Melon leaves" into a paste and treating various injuries and ulcers with external application.

[0004] In his early years as a doctor, the applicant used to pick and crush green leafy herbs to treat facial boils for his patients, with significant results. However, these fresh green leafy herbs had to be picked and crushed immediately, which was very inconvenient. Furthermore, in winter, most herbs shed their leaves, making them unavailable. To meet the needs of treating illnesses, many renowned pharmacists dried the green leafy herbs, ground them into powder, and then added excipients such as vaseline to make ointments for future use. While this treatment method makes green leafy herbs easier to store, readily available, and convenient to use, it loses the advantage of crushing fresh green leaves into a paste. The active ingredient, chlorophyll, is released much less than in a fresh herb paste, and its therapeutic effect is far inferior to that of a fresh herb paste. This drawback has remained largely unaddressed, remaining an unresolved issue. Summary of the Invention

[0005] In order to solve the above problems, the present invention provides a green gel paste application and a preparation method. The green gel paste application of the present invention is efficient and safe, has stable quality, is easy to use, has a wide range of applications, and is worthy of promotion and application, so that more patients can be relieved of their pain.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions:

[0007] The present invention provides a green gel paste patch, which includes a carrier, a protective film and a gel paste. The gel paste includes the following raw materials in parts by weight: 10-20 parts of dry powder made from green leaves and / or thin stems of plants, 7.5-15 parts of excipients, 2.3-5 parts of thickeners, 0.2-0.5 parts of preservatives and 40-80 parts of water.

[0008] As a preferred embodiment of the present invention, the plant green leaves and / or thin stems include one or more plant leaves and stems having external therapeutic effects.

[0009] As a preferred embodiment of the present invention, the water content of the green gel paste is 40-80%.

[0010] As a preferred embodiment of the present invention, the excipient includes vaseline or glycerin, liquid paraffin or vegetable oil.

[0011] As a preferred embodiment of the present invention, the thickener includes sodium alginate, gelatin, gum arabic or agar.

[0012] As a preferred embodiment of the present invention, the preservative includes potassium sorbate or sodium benzoate.

[0013] As a preferred embodiment of the present invention, the plant green leaves include Hibiscus mutabilis leaves, Raspberry, Lobelia chinensis, Rosa laevigata leaves, Momordica charantia leaves, Longleaf Frost green leaves, Betel nut leaves, Buddleja herb leaves, Amaranth leaves, Houttuynia cordata or Taraxacum officinale.

[0014] The present invention also provides a method for preparing the green gel paste patch, which comprises the following steps:

[0015] 1) Drying the green leaves and / or thin stems of the plant, crushing and passing through a fine sieve to obtain a dry powder;

[0016] 2) adding water, excipients, thickeners, and preservatives to the dry powder obtained in step 1) and stirring uniformly to obtain a green hydrogel paste;

[0017] 3) Spreading the green hydrogel paste obtained in step 2) on a carrier, placing the paste in a frame with a certain hardness, covering the surface of the paste with a protective film, placing the paste in an aluminum-plastic composite film packaging bag, and vacuum packaging to obtain a green gel paste application.

[0018] As a preferred embodiment of the present invention, in step 3), the green hydraulic paste is spread to a thickness of 4-6 mm.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] 1) The present invention selects any It has the effects of clearing away heat, reducing redness, relieving swelling and pain, and promoting blood circulation and removing blood stasis. The leaves and thin stems of green leafy herbs are dried and crushed into fine powder, and then several times the amount of water and a small amount of lubricant Vaseline, water-gelling thickener sodium alginate, and a trace amount of preservative potassium sorbate are added and mixed well to obtain green leaf hydrogel paste that looks like fresh herbal paste, is of better quality than fresh herbal paste, has the same therapeutic effect as fresh herbal paste, can be mass-produced, and stored for future use, becoming an innovative medical dressing product on the market.

[0021] 2) The green gel paste of the present invention can clear away heat and reduce redness, reduce swelling and relieve pain, promote blood circulation and remove blood stasis, draw out pus and heal sores. It has good efficacy in treating acute joint sprains, traumatic injuries, gout joint swelling and pain, skin furuncles, boils, carbuncles, sores, erysipelas, nameless swelling and poisonous swelling, and poisonous insect stings. It is highly effective, non-toxic, safe to use, and has stable quality.

[0022] 3) The green gel paste of the present invention has a water content of more than 60%, and has a good cooling effect on redness, swelling, heat and pain on the skin caused by inflammation or trauma.

[0023] 4) The green gel paste of the present invention has strong selectivity for application, and can be selected from various fresh herbal leaves with high chlorophyll content, rich leaf juice, and no toxicity. The raw material source is wide and the preparation method is simple. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a physical picture of the green gel paste application of the present invention.

[0025] Figure 2 This is a comparison chart of the effects of use on patients in Example 1.

[0026] Figure 3 This is a comparison chart of the effects of use on patients in Example 2.

[0027] Figure 4 This is a comparison chart of the effects of use on patients in Example 3.

[0028] Figure 5 This is a comparison chart of the effects of use on patients in Example 4.

[0029] Figure 6 This is a comparison chart of the effects of use on patients in Example 5.

[0030] Figure 7 This is a comparison chart of the effects of use on patients in Example 6.

[0031] Figure 8 This is a comparison chart of the effects of use on patients in Example 7.

[0032] Figure 9 This is a comparison chart of the effects of use on patients in Example 8.

[0033] Figure 10 This is a comparison chart of the effects of use on patients in Example 9. DETAILED DESCRIPTION

[0034] In order to make the technical means, creative features, purpose and efficacy of the present invention easy to understand, the present invention is further described below in conjunction with specific examples, but the following examples are only preferred embodiments of the present invention, not all. Based on the examples in the embodiments, other embodiments obtained by those skilled in the art without making creative work are within the scope of protection of the present invention. The experimental methods in the following examples, unless otherwise specified, are conventional methods, and the materials, reagents, etc. used in the following examples, unless otherwise specified, can be obtained from commercial channels.

[0035] The present invention provides a green gel paste application and a preparation method, comprising:

[0036] 1. Dry and crush the green leaves of one or more plants and pass them through a fine sieve (80 mesh or above) to obtain dry powder;

[0037] 2. Add the dried leaf powder to water, excipients, thickeners, and preservatives in sequence and stir evenly to form a soft, sticky, and juicy green gel paste.

[0038] 3. Spread the green gel paste on the cloth with a thickness of about 5mm, place the paste in a frame made of a certain hardness material, cover the surface of the paste with a protective layer of release paper, put it into an aluminum-plastic composite film packaging bag, and vacuum pack it. Figure 1 .

[0039] The ingredients are as follows: 10-20 parts of dry powder made from green leaves or thin stems of plants, 7.5-15 parts of excipients, 2.3-5 parts of thickeners, 0.2-0.5 parts of preservatives, and 40-80 parts of water.

[0040] Instructions: Open the inner bag of the product, remove the green gel cream, peel off the mesh on the surface, remove the cream border, apply the cream surface to the affected area, and wrap with a bandage. Alternatively, apply the cream surface to the affected area, then apply a gauze dressing, secure with adhesive strips, and change the dressing daily or every other day.

[0041] The varieties of green leaves and / or thin stems of raw materials are green leaf varieties commonly used by the people and fresh products listed in Chinese herbal medicine books for the treatment of traumatic injuries, closed skin and joint skin and soft tissue injuries, and inflammatory redness, swelling, heat and pain of furuncles, carbuncles and sores. They can be (but not limited to) hibiscus leaves, blackberry, lobelia, young leaves of golden cherry, bitter melon leaves, green leaves of longleaf frost, purple bead leaves, buddleja leaf, amaranth leaf, houttuynia cordata or dandelion, etc.

[0042] The excipient can be (but not limited to) oily substances such as vaseline or glycerin, liquid paraffin, vegetable oil, etc., so that the patch still has the anti-drying and moisturizing effect after the water evaporates during use.

[0043] Thickeners can be (but not limited to) sodium alginate or gelatin, gum arabic, agar, etc., so that it can be saturated with a large amount of water.

[0044] The paste in the green gel paste of the present invention may also be a combination of three ingredients: dry powder of plant green leaves (including a small amount of thin stems), water, and a thickener.

[0045] The green gel of the present invention can also be used directly in a paste form. To use: Use a tongue depressor to spread the gel onto a gauze dressing, apply it to the affected area, and then wrap it with a bandage or secure it with adhesive strips. Alternatively, the gel can be spread directly onto the affected area, followed by a gauze dressing and then a bandage. Alternatively, secure it with adhesive strips only, and change the dressing daily or every other day.

[0046] While treating a patient with a severe lip boil, it was pouring rain outside, making it impossible to go up the mountain to gather herbs. The inventors tried grinding up some herbal leaves left over from over ten days earlier. Because the leaves had naturally dried in the shade, the grinding did not produce a medicinal paste, but rather a powder. To convert the paste back into a medicinal paste, the inventors added water, which indeed resulted in a paste rich in juice. The patient recovered quickly, with the same therapeutic effect. However, the paste also exhibited shortcomings: rapid water evaporation, easy drying, and adhesion to the skin, making it difficult to remove. To overcome these shortcomings, the inventors added a small amount of petroleum jelly to the paste made by adding water to the green leaf herbal powder. This resulted in a moist, non-sticky, and easy-to-remove green leaf paste. Later, after repeated clinical observations, it was discovered that the green leaf paste did not have enough water content to meet the standards of a fresh herbal paste, and its viscosity was insufficient to retain water. To increase the amount of condensed water and achieve a thicker consistency, a thickener, sodium alginate, was added to the Green Leaf Paste. Furthermore, to extend its shelf life, a trace amount of potassium sorbate, a preservative, was added. The result is a Green Leaf Paste that preserves freshness, moisture, and quality. It boasts the same juicy, tender, and viscous appearance and therapeutic effects as a mashed medicinal paste, while also being easily stored for future use, stable in quality, and convenient to use. Over fifty years and tens of thousands of clinical trials, it has cured numerous skin, soft tissue, and soft tissue conditions, including boils, carbuncles, erysipelas, joint sprains, injuries from falls, gouty arthritis, and ulcers.

[0047] This invention involves drying and grinding fresh herbs into a fine powder, adding several times the amount of water, and then adding lubricating grease and a water-retaining thickener. The result is a new green gel and medical patch that resembles, but is superior to, fresh herbal paste. These two products have not been available before.

[0048] The water content of the green gel paste of the present invention is above 60%. To date, no other medical hydrogel patch product has such a high water content.

[0049] The gel-type medical dressing of the present invention is vacuum-packaged in an aluminum-plastic composite film bag, so that the moisture of the green gel in the product does not volatilize and is not oxidized and corrupted, and the shelf life is long.

[0050] The green gel paste of the present invention has the following effects:

[0051] 1) Cold compress effect: Green Gel Paste retains the characteristics of fresh herbal paste. The paste contains an appropriate proportion of water, which has a good cold compress effect on redness, swelling, heat and pain on the skin caused by inflammation or trauma.

[0052] 2) Transdermal absorption effect: Green gel cream contains more chlorophyll and mucilage. After being applied to the affected area on the body surface, it can be absorbed through the skin under the action of water molecules, penetrate into the skin and subcutaneous soft tissue, and exert its pharmacological effect.

[0053] 3) Buffering Effect: Green Gel Cream should be applied topically at a thickness of 5 mm. Initially, it acts as a cooling compress. As the cream's temperature gradually approaches body temperature, it acts as a buffer between the affected area and the outside world. This helps regulate airflow, temperature, humidity, and metabolism, facilitating healing and recovery.

[0054] 4) The effect of surrounding and draining pus: During the red, swollen, hot and painful inflammatory period of bacterial infectious skin diseases such as furuncles, carbuncles, cellulitis, etc., applying green gel ointment can surround the affected area, prevent it from spreading, gradually confine it to the affected area, force it to break through at the top of the center and drain pus, and even pull out the pus plug, so that the pus in the affected area will be exhausted and healed.

[0055] 5) Dispersing blood stasis, relieving swelling and alleviating pain: After more than 40 years of extensive clinical verification, it is shown that Green Ointment has a good effect of dispersing blood stasis, relieving swelling and alleviating pain for skin bruises, subcutaneous soft tissue stasis and swelling or hematoma caused by various types of inflammation and trauma.

[0056] Example 1

[0057] This embodiment provides an example of treating furuncle on the head and face:

[0058] See also Figure 2 The patient, Yang, female, 26 years old, was 5 months pregnant. Due to the hot summer, she developed 2 boils on her forehead and right face, which were red, hard, hot and painful. The treatment method was to apply green gel ointment only, for 4 days and 4 dressing changes.

[0059] Treatment results: Pus was drawn out and swelling was reduced, and the patient was cured without scar.

[0060] Example 2

[0061] This example provides an example of treating lip abscess:

[0062] See also Figure 3A 4-year-old patient, Zeng, developed a small boil below the right nose. This boil gradually grew larger, becoming red, swollen, hot, and painful, eventually leading to inflammation and swelling of the entire right side of the face and eye socket. Treatment included external application of green gel ointment and internal treatment with Western medicine for antibacterial and anti-inflammatory effects. Treatment lasted four days, with four dressing changes.

[0063] Treatment result: Healed without scars.

[0064] Example 3

[0065] This example provides an example of treating inflammatory swelling and pain in the left calf:

[0066] See also Figure 4 The patient, Mr. Chen, 25 years old, suffered from itching and scratching due to mosquito bites, which led to infection, resulting in redness, swelling, heat and pain on the inner side of the upper and middle parts of the left calf and the inner side of the lower left thigh for 3 days. The treatment method was green gel ointment application and bandaging. The treatment period was 3 days, and the dressing was changed 3 times.

[0067] Treatment results: significant improvement.

[0068] Example 4

[0069] This embodiment provides an example of treating furuncle on the left lateral ankle:

[0070] See also Figure 5 A 28-year-old patient, surnamed Liu, suffered a bruise on his left lateral ankle, which gradually enlarged. The boil, with a hard, non-ulcerated head, was accompanied by redness, swelling, heat, and pain in the surrounding tissues, as well as swollen left inguinal lymph nodes. Treatment included external application of Green Gel Ointment and internal treatment with Western medication for antibacterial and anti-inflammatory effects. Treatment lasted two days, with two dressing changes.

[0071] Treatment results: The pus from the hard head of the furuncle on the left lateral ankle subsided, the redness and swelling of the surrounding soft tissues disappeared, and the patient was cured.

[0072] Example 5

[0073] This example provides an example of the treatment of a child's left submandibular abscess:

[0074] See also Figure 6 A 5-year-old patient, surnamed Liu, developed a swelling under his left jaw that gradually grew larger and was accompanied by a fever. The affected area was red, swollen, hot, and painful, forming a raised mass with a mild sensation of fluid surging. Treatment: External treatment: drainage with gauze strips to dissolve dead tissue and promote tissue regeneration, and application of Puji ointment and Luning ointment. Internal treatment: Conventional treatment: Western medications for inflammation and fever reduction, along with other symptomatic treatments. Treatment lasted 14 days, with 12 dressing changes.

[0075] Treatment results: The wound has healed without scars, the opening and closing of the mouth and chewing functions are normal, there is no abnormality in appearance, and the patient is clinically cured.

[0076] Example 6

[0077] This example provides an example of treating left hand swelling and pain:

[0078] See also Figure 7 A 66-year-old patient, surnamed Zheng, was accidentally bitten on the back of his left hand by a venomous insect. Scratching the wound caused secondary infection, resulting in redness, swelling, and burning pain. Treatment consisted of a green gel ointment bandage. Treatment lasted eight days, with six dressing changes.

[0079] Treatment results: The swelling in the affected area has completely subsided and the disease has been effectively cured.

[0080] Example 7

[0081] This embodiment provides an example of treatment of right lateral ankle sprain:

[0082] See also Figure 8 The patient, Fang, 39 years old, fell and sprained the outer ankle joint of his right foot. The injured area was bruised and swollen, and it was painful to walk.

[0083] Treatment method: Green gel ointment application and bandage. Treatment duration is 3 days, and dressing changes are 3 times.

[0084] Treatment results: The swelling of the affected area has completely subsided, the function has been restored, and the disease has been effectively cured.

[0085] Example 8

[0086] This example provides an example of treating inflammatory swelling and pain in the right heel of a child:

[0087] See also Figure 9 A 3-year-old patient, Bian, fell and suffered a right heel sprain and plantar contusion. Due to improper treatment, inflammation, swelling, and pain developed at the site, which worsened daily. Treatment: Green Gel Ointment. Treatment lasted three days, with three dressing changes.

[0088] Treatment results: The swelling and pain in the affected area disappeared, the function was restored, and the patient could walk normally.

[0089] Example 9

[0090] This example provides an example of the treatment of right dorsum of foot hemostasis and abscess:

[0091] See also Figure 10 A 73-year-old patient, surnamed Xiao, sprained his left foot and developed a hematoma, which subsequently became suppurative. Despite treatment at multiple clinics and hospitals, his condition remained unresolved. The redness, swelling, heat, and pain in the affected foot worsened. Treatment included inserting a decomposing and tissue-regenerating gauze strip into the abscess cavity for drainage. Puji ointment was applied to the wound, and Lu Ning ointment was applied around the wound. Treatment lasted 27 days, with 10 dressing changes.

[0092] Treatment result: Healed without scars.

[0093] It can be seen that the green gel paste of the present invention can be applied to clear away heat and reduce redness, reduce swelling and relieve pain, promote blood circulation and remove blood stasis, draw out pus and heal sores, and has good efficacy in treating acute joint sprains, traumatic injuries, gout joint swelling and pain, skin furuncles, boils, carbuncles, sores, erysipelas, unknown swellings and poisonous insect stings, and is highly effective, non-toxic, safe to use and of stable quality.

[0094] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form or substance. It should be pointed out that ordinary technicians in this technical field can make several improvements and supplements without departing from the method of the present invention. These improvements and supplements should also be regarded as the scope of protection of the present invention. Any equivalent changes, modifications and evolutions made by technicians familiar with this profession without departing from the spirit and scope of the present invention by using the technical content disclosed above are all equivalent embodiments of the present invention; at the same time, any equivalent changes, modifications and evolutions made to the above embodiments based on the essential technology of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A green gel paste, characterized in that: The green gel paste comprises a carrier, a protective film and a gel. The gel comprises the following raw materials by weight: 10-20 parts of dry powder made from green leaves and / or thin stems of plants, 7.5-15 parts of excipients, 2.3-5 parts of thickeners, 0.2-0.5 parts of preservatives and 40-80 parts of water.

2. A green gel paste according to claim 1, characterized in that: The plant green leaves and / or thin stems include one or more plant leaves and stems with external therapeutic effects.

3. A green gel paste according to claim 1, characterized in that: The water content of the green gel paste is 40-80%.

4. The green gel paste according to claim 1, characterized in that: The excipients include vaseline or glycerin, liquid paraffin or vegetable oil.

5. The green gel paste according to claim 1, characterized in that: The thickening agent includes sodium alginate, gelatin, gum arabic or agar.

6. The green gel paste according to claim 1, characterized in that: The preservatives include potassium sorbate or sodium benzoate.

7. The green gel paste according to claim 1, characterized in that: Green leaves of plants include hibiscus leaves, blackberry, lobelia, golden cherry leaves, bitter melon leaves, long-leaf frost leaves, calliandra leaves, buddleja leaves, amaranth leaves, houttuynia cordata or dandelion.

8. A method for preparing the green gel paste according to any one of claims 1 to 7, characterized in that: The preparation method comprises the following steps: 1) Drying the green leaves and / or thin stems of the plant, crushing and passing through a fine sieve to obtain a dry powder; 2) adding water, excipients, thickeners, and preservatives to the dry powder obtained in step 1) and stirring uniformly to obtain a dark green hydrogel; 3) Spreading the dark green hydrogel paste obtained in step 2) on a carrier, placing the paste in a frame with a certain hardness, covering the surface of the paste with a protective film, placing the paste in an aluminum-plastic composite film packaging bag, and vacuum packaging to obtain a green gel paste application.

9. The method for preparing the green gel paste according to claim 8, characterized in that: In step 3), the green hydraulic paste is spread to a thickness of 4-6 mm.

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