The present invention relates to a building block of ecological slope protection vegetation, a fabrication method and a construction technique. The building block is composed of a growing bed body, a lath crib, planting troughs, a vegetation layer and a plant, the lath crib wraps the circumference of the growing bed body, the upper plane of the growing bed body is lower than the upper plane of the lath crib and concave, the vegetation layer is formed on the growing bed body, which matches the inner walls of the sectional area of the lath crib to form an integral building block, and more than one planting troughs are arranged on and run through the growing bed body. The design of the present invention is scientific, the structure is reasonable, the restoration of water ecology can reduce the operating cost, environment is improved, ecology is reinstated, harmonious natural beauty is enhanced, and the present invention is suitable for the nidification of small living creatures and the habitation and the survival of aquatic fishes, so that the cutting-off continuity of water and land regions is restored. The present invention is widely applied to channel slope protection, levee slopes, roadsides, airports, parks, public lands, household lawns, sports grounds, etc. The present invention is suitable for cold regions, damp regions, warm and damp intermediate zone, etc.