159 results about "Circular dichroism" patented technology

The invention provides a chiral super-structure surface and a dynamic regulation and control method for circular dichroism of the chiral super-structure surface, and belongs to the technical field of micro-nano optics. The chiral metasurface can perform differential absorption on vertically incident left-handed circularly polarized light and right-handed circularly polarized light. The chiral metasurface comprises: a substrate layer; the optical waveguide layer is arranged on the substrate layer; the nano structure layer is arranged on the optical waveguide layer and comprises a plurality of Z-shaped nano units which are periodically arranged in a square shape; and the hydrogel layer is arranged on the optical waveguide layer and the plurality of Z-shaped nano units and is used for dynamically regulating and controlling the circular dichroism of the chiral super-structure surface when the environment humidity changes. Under the condition that high circular dichroism of the chiral super-structure surface is achieved, the circular dichroism of the chiral super-structure surface is made to move when the environment humidity changes, and therefore the circular dichroism of the chiral super-structure surface is dynamically regulated and controlled.

The invention relates to the technical field of artificial electromagnetic metasurfaces, in particular to a full-space multifunctional terahertz metasurface. The metasurface is composed of a plurality of metasurface units arranged periodically, and each metasurface unit sequentially comprises a first metal structure layer, a first middle dielectric layer, a grating layer, a second middle dielectric layer and a second metal structure layer from top to bottom. The first metal structure layer and the second metal structure layer are the same in structure and each comprise two C-shaped metal rings, and the two C-shaped metal rings are connected in a staggered mode to form a disconnected and staggered S shape. The first intermediate dielectric layer and the second intermediate dielectric layer are consistent in thickness; the grating layer comprises vanadium dioxide and copper which are alternately arranged, and multifunctional dynamic regulation and control of transmission, reflection and the whole space are achieved by controlling phase change of the vanadium dioxide. The metasurface provided by the invention can respectively realize the functions of polarization conversion, linear-circular polarization wave conversion, circular dichroism, asymmetric transmission and the like in different states.

The invention discloses a thermal detection system and a chiral substance identification method, and relates to the technical field of micro-nano optics, the thermal detection system and the chiral substance identification method, based on the structure of the thermal detection system and the steps of the chiral substance identification method, a chiral substance to be detected is configured into a corresponding solution to be detected; a solution to be detected is sampled and placed in the absorber, the surface plasmon effect generated when the metal resonance layer receives chiral light irradiation is utilized, a corresponding thermal signal is output, then the thermal signal is captured and analyzed through the thermal detection system, and high-precision identification of chiral substances is achieved. Compared with a traditional circular dichroism and circular polarization fluorescence spectrophotometer device, the technical scheme provided by the invention is simple in structure, convenient to operate and relatively low in requirements on the concentration and the volume of a detected sample.

The invention discloses a phenoxazine derivative as well as a preparation method and application thereof, and belongs to the field of biological medicine synthesis. A series of phenoxazine derivatives are synthesized by using a simple, efficient and low-toxicity method, circular dichroism, fluorescence spectrum and ultraviolet absorption spectrum prove that the molecules not only have non-covalent interaction with DNA, but also can be subjected to transamidation reaction with the DNA to covalently modify the DNA, and meanwhile, the phenoxazine derivatives are relatively good in anti-tumor cell activity and relatively good in anti-tumor effect. And a new strategy is provided for the research of DNA targeted drugs.

The invention provides a Fe3O4 nano-particle microscopic imaging detection method based on left-handed and right-handed polarization modulation, belongs to the technical field of photo-thermal science and detection and signal processing, and solves the problems that at present, nano single particles are difficult to observe, and the physicochemical characteristics are difficult to obtain, the method specifically comprises the steps that a to-be-detected sample is determined, and a slide sample is prepared; starting a computer, a data acquisition card, a lock-in amplifier, a galvanometer controller and a function generator; starting an exciting light and probe light laser power supply and a refrigerator; detection parameters, laser power / current parameters and modulation parameters are set, and scanning detection is conducted on the detection sample piece; loading a magnetic field; the computer reads a signal from the data acquisition card to obtain a photo-thermal detection result image; different laser parameters and magnetic field sizes are changed, the steps are repeated, circular dichroism and magnetic circular dichroism detection results are obtained, magnetization curve measurement is carried out, and the single nanoparticle magnetic moment overturning process is monitored.

The invention discloses a SiO2 / CNC multi-optical characteristic composite film and a resin packaging preparation method, and the preparation method comprises the steps: firstly, preparing a SiO2 photonic crystal film based on polydisperse nano silicon dioxide of which the particle size is in specific normal distribution; and jointly assembling the rolled CNC photon microchip, polydisperse SiO2 with the particle size in specific normal distribution and a toughening material. According to the method, the brittleness of a CNC chiral photon film is utilized, and the chiral photon microchip which is unique in shape, gorgeous in structural color, gorgeous in circular dichroism and fine in fingerprint texture texture is prepared through rolling treatment. According to the combination mode, the influence of all components in the SiO2 system on the CNC film-forming property, the screw pitch controllability and the structural uniformity is eliminated, and finally the SiO2 / CNC composite film with multiple optical characteristics and excellent mechanical properties is obtained.

Nanostructured chiral microparticles with bowtie shape having widely variable pitch, size, thickness and length are provided. The self-limited assembly of anisotropic building blocks makes possible high synthetic reproducibility, size monodispersity and computational predictability of their geometries for different assembly conditions. They display multiple strong circular dichroism peaks originating from absorptive and scattering phenomena. Unlike classical chiral molecules, these particles display a continuum of Osipov-Pickup-Dunmur chirality measures that exponentially correlate with the spectral positions of the circular dichroism peaks. Bowtie particles with variable polarization rotation were utilized in printing photonically active metasurfaces with spectrally tunable positive / negative polarization signatures for light detection and ranging (LIDAR) devices.

The invention discloses an intrinsic chiral super-structure surface, an angle dispersion regulation and control method and application, and belongs to the field of super-structure surfaces, the intrinsic chiral super-structure surface comprises a plurality of achiral super-atom units, a top resonator comprises two semi-circular rings in mirror symmetry, one ends of opposite sides of the two semi-circular rings are provided with notches, and the other ends of the two semi-circular rings are provided with gaps. The other ends of the opposite sides of the two semicircular rings are bent inwards to form inward protrusions. According to the intrinsic chiral super-structure surface, the angular dispersion regulation and control method and the application, the achiral super-atoms with a single mirror symmetry axis are designed, and multiple interference effects of a metal-insulating medium-metal structure are combined; the ultra-strong circular dichroism (the absolute value is about 0.8, and the single-component absorption efficiency is 98%) of terahertz waves under oblique incidence and dynamic range polarization conversion cooperatively regulated and controlled by the incident angle and the geometric dimension of the super-atom facing and inward protruding are achieved, and a multi-angle and multi-parameter adjustable innovative scheme is provided for efficient reflection type terahertz device design.

The invention discloses a dynamic tunable chiral terahertz broadband absorber based on vanadium dioxide, the absorber is formed by periodically arranging M * N absorption units of a multilayer structure in an array, the absorption units are in M * N two-dimensional distribution, and both M and N are positive integers; the absorption unit comprises a metal substrate, a dielectric layer and a resonance layer which are sequentially arranged from bottom to top; the metal substrate and the dielectric layer are rectangular; the resonance layer comprises a J-shaped metal patch, and an inverted-T-shaped vanadium dioxide patch is arranged at one end of the J-shaped metal patch. The terahertz chiral absorber can have a circular dichroism (CD) value larger than 0.8 within the range of 5.36-7.69 THz, the mirror image enantiomer of the terahertz chiral absorber can also achieve a CD spectrum opposite to the mirror image enantiomer, and the terahertz chiral absorber has the advantages of being high in CD, dynamically tunable and simple in structure. In addition, the invention also discloses a preparation method of the dynamic tunable chiral terahertz broadband absorber based on vanadium dioxide.

A terahertz-band metasurface circular dichroic device based on liquid crystal elastomers, and a preparation method therefor. The metasurface circular dichroic device comprises a dielectric layer (1), a plurality of movable structural main bodies (2) and a plurality of liquid crystal elastomers (3), wherein the movable structural main bodies (2) are periodically attached onto the dielectric layer (1); the liquid crystal elastomers (3) are attached to a part of each movable structural main body (2); and the response of the metasurface circular dichroic device can be adjusted by means of structural changes in the movable structural main bodies (2). Circular dichroism values are flexible and adjustable at different frequencies by means of the different bending degrees of microstructural metal sheets (22) inside the movable structural main bodies (2). By means of the attachment of the liquid crystal elastomers (3), the response performance and the flexibility of the metasurface circular dichroic device are further improved, thereby further improving the usage flexibility of detection while simplifying the structure of the circular dichroic device, and facilitating the detection on chiral molecules.

The invention provides a reversible circular dichroism metasurface based on a light-operated phase change material GSST and a regulation and control method of the reversible circular dichroism metasurface. The reversible circular dichroism metasurface comprises a plurality of unit structures which are periodically arrayed along an XOY plane, each unit structure comprises a gold substrate layer, a silicon dioxide dielectric layer and a composite functional material layer which are sequentially stacked from bottom to top in the Z-axis direction; the composite functional material layer comprises a gold material rectangular strip and four GSST material rectangular strips; the gold material rectangular strip is arranged in the middle of the upper surface of the silicon dioxide dielectric layer, and the length direction is parallel to the Y axis; the length directions of the four GSST material rectangular strips are parallel to the X axis, and the four GSST material rectangular strips are perpendicularly connected to the two sides of the two ends of the gold material rectangular strip correspondingly, so that the overall shape of the composite function material layer is of an I-shaped symmetrical structure. Reversible circular dichroism regulation and control are realized, and the circular dichroism regulation and control device has the advantages of simple structure, high response speed and repeatability.

The invention belongs to the technical field of chiral nano materials, and particularly relates to a chiral porphyrinyl COF nanosheet as well as a preparation method and application thereof. The ultrathin chiral porphyrin-based COF nanosheet is prepared through induction of phenylethylamine which is an isomer by adopting an acoustochemical room-temperature ultrasonic synthesis method, is uniform in thickness, has good crystallinity and large transverse size, has opposite circular dichroism (CD) signals, can be used as a chiral solid fluorescence detector, and can be used as a solid fluorescence detector. The method is used for detecting enantiomers of the same chiral compound.

The invention provides an optical module, a debugging method and optical equipment. The optical module comprises a display panel, a first cholesteric liquid crystal film, a first electric control dimming device and a second cholesteric liquid crystal film, the first cholesteric liquid crystal film is arranged on the light emitting side of the display panel, the second cholesteric liquid crystal film and the first cholesteric liquid crystal film have the same circular dichroism, and the second cholesteric liquid crystal film and the first cholesteric liquid crystal film are configured to reflect polarized light with the same rotation direction as the first cholesteric liquid crystal film and transmit polarized light with the rotation direction opposite to the first cholesteric liquid crystal film; the first electric control dimming device is configured to be time division multiplexing, can convert the transmitted polarized light into polarized light with opposite rotation directions in a power-off state, and maintains the polarization state of the transmitted polarized light in a power-on state. According to the optical module, when the polarized light is transmitted and reflected at the first cholesteric liquid crystal film and the second cholesteric liquid crystal film and is emitted from the first electric control dimming device in different polarization states, light loss cannot be generated, and the light emitting brightness and the imaging quality of the optical module can be guaranteed.

Provided are a non-ribosomal antifungal peptide MaAFP1, a preparation method therefor and a use thereof. The molecular formula of the antifungal peptide MaAFP1 is C41H74N18O12, wherein an amino acid sequence from the N-terminus to the C-terminus is (D)Arg-(L)Arg(OH)-(D)Orn-(L)Thr-(D)Orn-(L)Arg(OH)-(D)Tyr. Fermentation is performed by using Metarhizium anisopliae CQMa421, a fermentation broth is collected, and separation and purification are performed by means of ion exchange chromatography and high performance liquid chromatography so as to obtain the antifungal peptide MaAFP1. The structure of MaAFP1 is analyzed by comprehensively using an Edman degradation method, mass spectrometry, infrared spectroscopy, nuclear magnetic resonance spectroscopy, and circular dichroism spectroscopy. By performing an in vitro bacteriostatic test, it is found that MaAFP1 has a good inhibitory effect on a variety of animal and plant pathogenic fungi, and has the value of the development of a novel antibacterial drug.

The invention belongs to the technical field of high polymer chemistry and material science, and particularly relates to application of a salicylaldehyde Schiff base chiral polymer in iron and copper ion detection, and the structural formula of the salicylaldehyde Schiff base chiral polymer is one of the following structures shown in the specification. . The salicylaldehyde Schiff base chiral polymer has high selectivity to copper ions and iron ions, and qualitative detection of the copper ions and the iron ions can be achieved according to changes of ultraviolet absorption spectrums, digital circular dichroism spectrums and fluorescence spectrums before and after coordination of the salicylaldehyde Schiff base chiral polymer with the copper ions and the iron ions.

The present invention provides a method for detecting and identifying molecular chirality based on a composite plasmon chiral nanostructure. The present invention constructs a composite plasmon chiral nanostructure using chiral nanofibers and gold nanorods as basic components, and achieves molecular chirality recognition and detection through plasmon chiral optical amplification. The excellent plasmon circular dichroism optical properties of the composite nanostructure can convert the host-guest chiral recognition interaction occurring at the fiber interface into an asymmetric plasmon chiral optical amplification signal. This technology can detect and identify the chiral enantiomers of amino acid molecules in about 1 minute, with a sensitivity of 10 ‑6 mol / L. This structure can also be used for quantitative analysis of molecular enantiomeric excess (ee), with a detection sensitivity of ±0.05. Furthermore, given that the chiral host-guest complexes involved in this technology are primarily based on hydrogen bonding interactions, the chiral fiber host can be used as a universal substrate for the detection of chiral amino acid molecules.

The invention discloses an adjustable circular dichroism chiral metasurface based on photosensitive silicon. The metasurface is composed of an upper layer photosensitive silicon material, a middle dielectric layer photosensitive silicon material and a substrate silicon material. The circular dichroism chiral metasurface provided by the invention can realize regulation and control of transmissivity and reflectivity in a wave band of 3.35-3.55 THz, so that the circular dichroism of transmission and reflection is regulated. Wherein the maximum value of the transmission circular dichroism can reach 0.62, the minimum value of the transmission circular dichroism is close to 0, and the regulation range is 0.62; the maximum value of the reflection circular dichroism can reach 0.63, the minimum value of the reflection circular dichroism is close to 0, and the regulation range is 0.63. By changing the conductivity of the photosensitive silicon, the wide dynamic regulation and control of the circular dichroism are realized.

The invention discloses chiral gold nanoparticles for an alkaline electrolysis water oxygen evolution reaction catalyst and a synthesis method and application thereof, L-shaped gold nanoparticle branched particles and D-shaped gold nanoparticle branched particles of chiral multi-branched gold nanoparticles are synthesized, and the chiral multi-branched gold nanoparticles are further used for catalyzing an oxygen evolution reaction. In the synthesis process, the chiral strength of a sample can be regulated and controlled by regulating and controlling the concentration of the chiral ligand, and the chiral strength can be reflected through the signal strength of circular dichroism. Compared with the prior art, the preparation method is simple, the manufacturing cost is low, and the catalytic performance of the oxygen evolution reaction is excellent. The oxygen evolution reaction performance of the L-shaped gold nanoparticle branch type particles in the sample is far superior to that of D-shaped gold nanoparticle branch type particles. Under the current density of 10 milliamperes per square centimeter, the L-shaped gold nanoparticle branch type particles reach 355.1 millivolts and 449.7 millivolts, the Tafel slope reaches 61.72 millivolts per ten degrees, the stability can be kept for 24 hours under the current density of 10 milliamperes per square centimeter, and the stability is good.

The invention belongs to the technical field of biology, and particularly relates to regulation and control of cinnamyl aldehyde on hyperuricemia related gene promoter region G quadruplex. According to the application disclosed by the invention, firstly, the capacity of cinnamyl aldehyde for regulating and controlling a G quadruplex in a hyperuricemia related gene promoter region is explored by utilizing circular dichroism, and the influence of cinnamyl aldehyde on regulation and control of a nucleic acid structure is further evaluated by utilizing a fluorospectro photometer, so that support is provided for a molecular mechanism of cinnamyl aldehyde for relieving hyperuricemia on a gene level. In conclusion, the invention discloses a brand new mechanism that cinnamyl aldehyde regulates and controls uric acid metabolism related genes through a targeted G quadruplex structure, a precise action target and a potential drug development direction are provided for treatment of hyperuricemia, and meanwhile, an established small molecule and G quadruplex interaction verification method provides technical reference for similar research.

The invention discloses a dual-wavelength circular dichroism refractive index sensor, which belongs to the optoelectronic device technology, and comprises an MgF2 substrate, first elliptical nano-columns are arranged on the MgF2 substrate in a rectangular array, second elliptical nano-columns are arranged on the MgF2 substrate in a rectangular array, and the first elliptical nano-columns and the second elliptical nano-columns are arranged in a staggered manner. The orientation angle of the first elliptical nano-column is theta 1, the orientation angle of the second elliptical nano-column is theta 2, and theta 1 is not equal to theta 2 and-theta 2. According to the mode, based on the principle of a continuous spectrum bound state, chiral resonance with strong circular dichroism and high quality factors is realized at the same time of mid-infrared dual wavelengths; in the refractive index sensing application, the sensor has a single-wavelength circular dichroism sensing mode and shows ultrahigh sensitivity and an excellent sensing merit figure; meanwhile, the refractive index sensor has a dual-wavelength circular dichroism sensing mode, the refractive index change is represented by wavelength spacing, the stability of the sensor is effectively improved, and the refractive index sensor with high performance and high stability is realized by combining the two sensing modes.

The invention discloses a strong circular dichroism chiral metasurface design based on a QBIC resonance structure. The metasurface is composed of two groups of silicon medium rods which are symmetrical about an original point. Each group of medium rods comprises an elliptic cylinder and a long cube, the positions and heights of the elliptic cylinder and the long cube are different, and the elliptic cylinder structure is kept in a floating state. According to the invention, the circular dichroism can reach 0.86 when the wavelength is 657 nanometers, and the circular dichroism in the range of 650-664 nanometers is greater than 0.6, so that an enhanced circular dichroism response function is achieved. The characteristic is derived from a QBIC resonance structure formed by two groups of silicon dielectric rods. By continuously optimizing the structure, the metasurface with a stronger circular dichroism effect can be obtained. The invention provides a novel method for flexibly adjusting and enhancing circular dichroism in nano photonics. By virtue of the unique optical characteristics, the design of the invention is expected to be widely applied in the fields of biosensing, optical communication, quantum technology and the like.

The invention discloses a bionic circular dichroism optical encryption device based on a tiger structure, and the device comprises a first substrate, a first conductive layer, a first electrode patch, an information encryption layer, a second conductive layer, a second electrode patch, and a second substrate. Wherein the information encryption layer adopts a double-layer Z-shaped structure design to simulate a tiger function, an upper layer fixing structure corresponds to a left half tiger of a palm tube, and a lower layer dynamic rotating structure corresponds to a right half tiger held by a user. A ciphertext transmission system is constructed by regulating and controlling three key parameters of an inclination angle, a rotation angle and an electromagnetic wave incidence angle of the lower layer structure, and steganography information can be accurately decrypted by using a specific CD key only when the three key parameters meet preset matching conditions at the same time. According to the invention, the dynamic adjustable circular dichroism (CD) is innovatively realized, and an optical security system for information encryption is constructed through the bionic design of key matching.

The present invention discloses a circular dichroism detection device, a preparation method thereof, and a detection method thereof. The circular dichroism detection device is a micro - spiral fiber grating, which comprises a plurality of completely identical micro - spiral fiber grating segments with a period of P. Each micro - spiral fiber grating segment comprises a plurality of gratings with a reference grating period of Λ0, wherein the period P and the reference grating period Λ0 satisfy: Λ0 = λ0 / Δn, P = λ 0* Λ 0* s / |λ w ‑λ0|, λ w is the working central wavelength required for circular dichroism detection, λ0 is the reference central wavelength of the input left - and right - circularly polarized light, s is the waveguide dispersion correction factor of the original optical fiber for making the micro - spiral fiber grating, and Δn is the refractive index difference of the coupling mode. When the circular dichroism detection device of the present invention is immersed in a solution of a left - or right - handed chiral substance, the power changes of the left - or right - circularly polarized light with a specific wavelength passing through the detection device are different, and thus the type of chiral substance in the solution can be detected. The circular dichroism detection device of the present invention is simple to manufacture, has a fast detection speed, and high stability.

The application provides a Fe3O4 nanoparticle microscopic imaging detection method based on left and right polarization modulation, belongs to the technical field of photothermal science and detection and signal processing, and solves the problems that current nanometer single particles are difficult to observe and physical and chemical characteristics are difficult to obtain, and specifically comprises the following steps: determining a sample to be detected and preparing a slide sample; starting a computer, a data acquisition card, a lock-in amplifier, a galvanometer controller and a function generator; starting a power supply of an excitation light and a detection light laser and a refrigerator; setting detection parameters, setting laser power / current parameters, setting modulation parameters, and scanning and detecting the sample to be detected; loading a magnetic field; reading signals from the data acquisition card by the computer to obtain a photothermal detection result image; changing different laser parameters and the size of the magnetic field, repeating the above steps, obtaining a circular dichroism and magnetic circular dichroism detection result, measuring a magnetization curve, and monitoring a single nanoparticle magnetic moment flipping process.

The invention discloses a tunable narrow-band chiral metasurface based on a silicon and germanium-antimony-tellurium composite nanostructure. The tunable narrow-band chiral metasurface comprises a substrate and a silicon and germanium-antimony-tellurium composite chiral metasurface formed on the surface of the substrate, the surface of the silicon and germanium-antimony-tellurium composite chiral super-structure comprises a plurality of silicon and germanium-antimony-tellurium composite chiral nano-structures which are periodically arranged, and each chiral nano-structure is composed of two rectangular nano-rods which are vertically connected and is in an L shape; the silicon and germanium-antimony-tellurium composite chiral nanostructure is a germanium-antimony-tellurium and silicon double-layer chiral nanostructure from bottom to top. The silicon and germanium-antimony-tellurium composite chiral super-structure surface disclosed by the invention can realize narrow-band circular dichroism response in an infrared band, and the wavelength of the narrow-band circular dichroism response can be dynamically adjusted through germanium-antimony-tellurium phase change.

The application discloses a method for detecting glutathione by using manganese-based chiral nanomaterials, and belongs to the field of chemical engineering, specifically to the field of analytical chemistry technology. The method comprises the following steps: taking a dispersion liquid of manganese-based chiral nanomaterials as a detection reagent, mixing the detection reagent with a sample containing glutathione to be detected, and comparing a circular dichroism spectrum signal with a standard curve to obtain the concentration of the sample containing glutathione to be detected; wherein a chiral ligand of the manganese-based chiral nanomaterials is ribose. Based on the circular dichroism spectrum detection, the detection wavelength band used is in the visible light region, is not easy to be disturbed, is sensitive, and the resolution can reach 3 muM, and the detection limit is 1.5 muM, which has important significance and value for promoting the development of the fields of optics, life science, medicine and the like.

The invention discloses a circularly polarized light-emitting diode based on a chiral metasurface and chiral molecular perovskite, and belongs to the technical field of chiral light-emitting diodes. The amorphous silicon layer is provided with a Z-shaped groove array, a perovskite material is filled in a Z-shaped groove, and a corresponding silicon and perovskite layer, namely a chiral metasurface regulation and control light-emitting layer, is formed; the left-hand structure Z-shaped groove is correspondingly filled with a left-hand chiral perovskite material, and the right-hand structure Z-shaped groove is correspondingly filled with a right-hand chiral perovskite material. By using the chiral metasurface of the Z-shaped array structure, the circular dichroism emission of the perovskite fluorescence wave band is realized by adjusting parameters. A chiral structure is combined with perovskite to serve as a light-emitting layer, chiral response of the structure is combined with chiral induced spin selectivity of a chiral perovskite material, and the circular dichroism of a red light LED is enhanced.

The invention relates to the technical field of circular dichroism application, and particularly discloses an asymmetric H-type micro-nano structure for realizing strong circular dichroism, the asymmetric H-type micro-nano structure comprises a substrate layer and a micro-nano structure layer, the micro-nano structure layer is arranged on the substrate layer, and the micro-nano structure layer comprises chiral units arranged periodically. The H-type nanostructure is endowed with chiral characteristics. When the asymmetric H-type nano structure is excited by circular polarized light, the asymmetric H-type nano structure can generate a surface plasmon resonance phenomenon. Particularly, the number and the coupling mode of the generated harmonic oscillators under the excitation of the right-handed circular polarized light are obviously different from the number and the coupling mode of the dipoles generated under the excitation of the left-handed circular polarized light.

The invention discloses a multi-mode circular dichroism chiral metasurface design based on an adjustable material. The metasurface structure is composed of a thermal phase change material VO2 and an electric phase change material Dirac on the upper layer, a polyimide dielectric layer in the middle and a gold substrate. The provided circular dichroism chiral metasurface can achieve regulation and control of the transmissivity and the reflectivity within the frequency band of 0.6-0.8 THz, and then the reflection circular dichroism is effectively controlled. The maximum value of the reflection circular dichroism of the metasurface can reach 0.69, the minimum value of the reflection circular dichroism of the metasurface can be close to 0, and regulation and control functions under four working modes are achieved. By changing the conductivity of the thermal phase change material VO2 and the electrical phase change material Dirac, dynamic regulation and control of four circular dichroism states are realized.

The invention belongs to the technical field of biological medicine, discloses a bicyclic terpenoid ester compound, a preparation method and application, and particularly relates to a bicyclic terpenoid ester compound separation and purification method and alpha-glucosidase inhibitory activity of the bicyclic terpenoid ester compound, and the bicyclic terpenoid ester compound separation and purification method comprises the steps of colletotrichum fasciculatum large-scale fermentation, methanol ultrasonic extraction, vacuum concentration and ethyl acetate extraction. According to the method, the bicyclic terpenoid ester compounds in the colletotrichum fasciatum are separated and purified through the steps of normal phase column chromatography, high performance liquid chromatography separation and purification and the like, and various modern spectrum analysis technologies such as nuclear magnetic resonance spectrum, high resolution mass spectrum, infrared spectrum, ultraviolet-visible spectrum and circular dichroism spectrum are combined, so that the content of the bicyclic terpenoid ester compounds in the colletotrichum fasciatum is improved. The bicyclic terpenoid ester compound is obtained from a colletotrichum fasciculatum solid fermentation product, and the alpha-glucosidase inhibitory activity of the compound is determined. The compound is obtained by being separated from a solid rice fermentation product of a colletotrichum dematium strain, and the colletotrichum dematium strain is separated from the root part of dianthus dematium. The compound has relatively strong inhibitory activity on alpha-glucosidase, has an IC50 value of 16.8 [mu] M, and can be used for preparing hypoglycemic drugs.