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Chiral sensing element and equipment, chiral representation method as well as concentration representation method

A technology for sensing elements and sensing equipment, applied in the fields of concentration characterization, chiral sensing elements, and equipment, can solve problems such as reducing sample detection efficiency, increasing system prices and sample testing costs, and reducing implementation costs and testing costs. , Reduce the cost of detection, the system achieves simple results

Inactive Publication Date: 2017-08-11
SICHUAN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This increases the price of the system and the cost of sample testing, and reduces the efficiency of sample testing

Method used

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  • Chiral sensing element and equipment, chiral representation method as well as concentration representation method
  • Chiral sensing element and equipment, chiral representation method as well as concentration representation method
  • Chiral sensing element and equipment, chiral representation method as well as concentration representation method

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Embodiment Construction

[0025] The present invention will be further described below by way of examples.

[0026] Such as figure 1 As shown, the chiral sensing device of this embodiment includes the following components in sequence: a parallel light modulation system 110 , a linearly polarized light and circular polarized light switching system 120 , a chiral sensing element 100 , and an optical signal receiving system 130 . in:

[0027] The parallel light modulation system 110 can have different light path configurations, which allow the optical components to be placed in a desired manner to obtain a parallel light beam. In a specific embodiment one, the component 110 is composed of a broadband light source 1, a first lens 2, a second lens 3, a first diffuse mirror 4, a first diffuse mirror 5, a third lens 6, and a fourth lens 7 and slit 8. Such as figure 1 As shown, the divergent light emitted by the broadband light source 1 (which may be a common white light source) is modulated into parallel ...

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PUM

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Abstract

The invention relates to the field of biological detection and provides a chiral sensing element and equipment, a chiral representation method as well as a concentration representation method, so that the detection sensitivity of molecular chirality is improved; the equipment and detection cost is reduced, and the detection efficiency and accuracy are improved; meanwhile, high-sensitivity representation of concentration of biological molecules in a solution is realized. The chiral sensing equipment comprises the chiral sensing element, the chiral sensing element comprises an upper covering layer, a middle covering layer and a lower covering layer which have light transmission, as well as a microfluidic channel formed by the upper covering layer, the middle covering layer and the lower covering layer; a chiral nanostructure array is arranged on the lower covering layer in the microfluidic channel. The invention applies to detection of weak circular-dichroism signals.

Description

technical field [0001] The invention relates to the field of biological detection, in particular to a chiral sensing element, a device, a chiral characterization method, and a concentration characterization method. Background technique [0002] Chirality refers to the phenomenon that a geometric structure or point group cannot coincide with its mirror image. This phenomenon is very common and very important in nature. In the field of life sciences, chiral molecules with molecular structures that are mirror images of each other are called enantiomers, which have almost identical physical and chemical properties. However, living organisms prefer one chirality. In fact, almost all sugars, proteins and DNA in the living body have the same chirality. These chiral substances create a chiral environment in the living body, which maintains the operation of life. This operation of life is very sensitive to the chirality of incoming living matter. Once a substance with the opposi...

Claims

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Application Information

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IPC IPC(8): G01N21/19G01N21/21G01N21/23
CPCG01N21/19G01N21/21G01N21/23G01N2021/216G01N21/554
Inventor 侯宜栋李燮高福华杨龙龙杜惊雷张儒譞谢端吴轩楠
Owner SICHUAN UNIV
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