17 results about "Pathogenic organism" patented technology

The present disclosure relates to methods for analyzing nucleic acid molecules present in a sample, wherein the DNA molecules present in the sample or derived from nucleic acids in the sample are contacted with a terminal deoxynucleotidyl transferase to add nucleotides to the 3' end of the DNA molecules in a step-wise fashion and then identifying the contacted DNA molecules by their sequence. The method can be advantageously used in methods of diagnosing diseases caused by pathogenic organisms, as well as detecting the presence of pathogenic organisms in the environment.

Devices, kits and methods are provided to reduce or even eliminate fecal contamination and cross-contamination and transmission of fecal-born pathogenic organisms by users employed in the food production and food preparation industries or users in a home, for example in restaurants, cruise ships, schools, hospitals, dormitories, transportation means and terminals, and government buildings, the devices and methods pertaining to a glove-like garment that is applied prior to disposal of feces and removed after disposal of toilet tissue. The glove is flushable, and in an embodiment includes means of retraction from the wrist area for inversion of the garment, followed by flushing the inverted removed glove.

Containers for growth of cryo-sprouts with reduced numbers of pathogenic organisms. The covered containers have an air-permeable seal and may also have additional openings to increase the air permeability rate of the covered container. The air permeability rate is balanced to have sufficient air exchange but with an evaporation rate that is low enough to avoid addition of water during germination and growth of the cryo-sprouts. The seeds and sufficient water are added to the container and covered with a lid to form an air-permeable covered container. The seeds germinate and grow in the covered container at pathogen antagonistic temperature without the removal of the lid until use by consumer. This results in cryo-sprouts that have reduced numbers of pathogenic organisms, are greener, and have an extended shelf-life.

The invention is directed to disinfection of object(s) in a space using a UV emitter. A calibration process is performed in which one or more UV sensors are placed proximate the object or set of objects to be disinfected. The sensor(s) measure a UV dose and the time taken for the UV dose to equal to a level suitable for disinfection to occur to the required level is measured. This is saved in a database in association with an identification of the object(s) being disinfected. This saved program can be activated subsequently and without the sensors present to disinfect the object(s). In addition to the calibration process, or in the alternative, the controller may enable the operator to select a particular pathogenic organism or set of organisms as a target of the disinfection process, with the controller accessing the database to obtain a disinfection program specific to the target.

The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.

Described herein are fusion proteins and methods of using those fusion proteins for the detection and identification of analytes (e.g., multimeric proteins expressed by pathogenic organisms or mammalian cells). In some embodiments, it includes a plurality of pairs of fusion proteins distinct for one analyte wherein each pair comprises i) a first fusion protein comprising one or more binding domains fused to a first portion of a reporter protein, and ii) a second fusion protein comprising one or more binding domains fused to a second portion of the same reporter protein, wherein the first and second portions of the reporter protein, when together, comprise the reporter protein in its entirety and restore its function, wherein the first fusion protein and / or the second fusion protein further comprises a fluorophore, and wherein the fluorophore for each pair has a distinguishable emission spectrum.

This invention discloses a method and system for detecting pathogenic organisms in aquatic bodies, belonging to the field of biological detection technology. Based on historical hydrological data and meteorological forecasts, a spatiotemporal distribution model of microbial concentration is constructed to generate a set of coordinates for suspected high-risk areas for pathogens. An unmanned surface vessel (USV) automatically cruises according to the coordinates and conducts water sampling and membrane enrichment, while simultaneously monitoring water temperature, pH, turbidity, and enrichment membrane pressure difference in real time, dynamically determining whether to terminate sampling. After the enriched samples are activated by electric field, magnetic field, or temperature control, real-time quantitative PCR is performed to obtain Ct values ​​at each location, calculate the offset density cumulative index, and identify areas with strong positive signals. Finally, based on the Ct value distribution and prediction results, a spatial distribution map and multi-level concentration map of pathogenic organisms are output for water quality risk assessment and emergency response. This invention has highly automated, spatially accurate, and intelligent analysis capabilities, and is suitable for pathogen monitoring and dynamic early warning in large-scale complex water bodies.

Devices and methods are described for disinfection of pathogenic organisms using pulsed DC field electroporation. For example, this disclosure describes disinfection of pathogenic organisms using pulsed DC field electroporation for lung infection treatment, blood infection treatment, sterilization, and respirators.

The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.

The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.

The present disclosure relates to methods for analyzing nucleic acid molecules present in an obtained sample, such as cell-free DNA molecules, wherein the nucleic acid molecules present in the sample are contacted in the sample with a terminal deoxynucleotidyl transferase to add nucleotides to the 3 ' end of the DNA molecules in a step-wise fashion and then identifying the contacted DNA molecules comprising the added nucleotides by their sequence. The method can be advantageously used in methods of diagnosing diseases caused by pathogenic organisms, as well as detecting the presence of pathogenic organisms in the environment.

The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.

The invention describes a novel method and alcohol-based compositions for the topical treatment of Treponema-associated digital dermatitis in equines, containing at least one or more different monohydric alcohol compounds, characterized in that they additionally contain at least one or more surfactants, one or more polyhydric alcohol compounds, and may further contain, depending on the intended use, one or more aldehyde compounds, one or more organic and / or inorganic acids, one or more organic and / or inorganic basic compounds, one or more inorganic and / or organic salts, one or more compounds from the group of essential oils, and active ingredients that are subject to drug regulations and, in particular, originate from the group of antibiotics. These products can also be used as cleaning and disinfecting agents on keratinized body parts and the coat of horses colonized with pathogenic organisms, as sprays, bath additives, or in gel form. The procedure particularly includes therapy in combination with the systemic administration of antimicrobial agents from the macrolide or penicillin groups.

The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.

An ostomy barrier, skin adhesive, accessory or a peristomal skin treatment comprises a population of non-pathogenic bacteria, fungi, algae, yeast or their lysates configured to limit proliferation of pathogenic organisms in or on peristomal skin or skin at other body sites and / or maintain healthy skin flora. The ostomy barrier, adhesive, accessory or peristomal skin treatment can also be configured to alter the peristomal or other skin environment to promote growth of a desirable or commensal population while discouraging growth of the pathogenic organisms.

A device for reducing oocysts of Eimeria spp. uses microwave. In the device, when breeding broiler chickens, litter is recycled for second to fifth breeding after first breeding, and the hardened litter is crushed through a crushing device to form a floor similar to a first breeding environment and simultaneously microwaves of a microwave device are irradiated onto the crushed litter, so that various pathogenic organism such as oocysts of Eimeria spp., viruses, bacteria, parasites, and fungi in the litter are reduced or killed, and thus, pathogenicity and mortality become low, thereby healthily and safely breeding broiler chickens, and accordingly, providing great economic help to poultry farms.

The application provides a method for preventing and controlling ciliates pathogenic organisms of aquatic animals, that is, an engineering strain for targeting DHC7 gene of heterakis sparrow-saku based on CRISPR system. The method for preventing and controlling ciliates pathogenic organisms of aquatic animals based on CRISPR-Cas system can not only make up for defects such as poor targeting and water pollution of chemical methods, but also overcome problems such as poor targeting and single prevention effect of existing biological methods, and realize efficient and targeted prevention and treatment of heterakis sparrow-saku disease. Meanwhile, the method can be further expanded to study the functions of specific genes, including the role of pathogenic genes in the invasion and pathogenic process of heterakis sparrow-saku, and has a promoting effect on the subsequent research of drugs with higher targeting efficiency.