The invention discloses Dong nationality medicinal liquor. The Dong nationality medicinal liquor is prepared from the following raw materials in parts by weight of 15-25g of Chinese wolfberry fruits,30-40g of rhizoma polygonati, 20-30g of radix codonopsis, 30-40g of fleeceflower roots, 10-20g of longans, 25-35g of radix rehmanniae preparata, 10-20g of radix angelica sinensis, 15-25g of poria cocos, 15-25g of radix ophiopogonis, 25-35g of radix rehmanniae, 10-20g of rhizoma drynariae, 35-45g of cortex eucommiae, 10-20g of rhizoma alismatis, 15-25g of radix polygalae, 10-20g of radix astragali,25-35g of herba cistanches, 15-25g of morinda roots, 15-25g of spina date seeds, 15-25g of Chinese yams, 25-35g of dateplum persimmons, 15-25g of red jujubes, 10-20g of Chinese magnoliavine fruits, 45-55g of crystal sugar, 450-550g of cobras, 350-450g of long-noded pit vipers, 350-450g of pallas pit vipers and 550-650g of ophidia black snakes. Through reasonable compatibility of traditional Chinese medicines, the Dong nationality medicinal liquor has notable treatment effects on multiple diseases.