36 results about "Individual dose" patented technology

The invention provides a radioactive biological experimental facility radiation environment monitoring and personal dose monitoring method, which comprises a fixed radiation dose monitor, a portable radiation dose monitor, a personal dose instrument, an experimental facility computer system docking port, an analysis center and an early warning judgment module, the experimental facility environment radiation dose can be monitored in real time, single-time operation personal cumulative doses under three different conditions can be obtained through an experimental facility computer system, radiation dose summary analysis can be carried out on radioactive sources operated in the experimental facility, radiation dose changes under different radioactive source operations are obtained, and the experimental facility environment radiation dose monitoring system can be used for monitoring the experimental facility environment radiation dose in real time. And finally, performing early warning according to the environmental radiation dose and the individual accumulated dose result. The environment radiation state can be monitored timely, accurately and effectively, and the external irradiation dose of personnel can be monitored and evaluated in real time.

The invention provides a radioactive source personal dose real-time monitoring device and a radioactive source personal dose real-time monitoring method based on a double-range self-adaptive mechanism. The radioactive source personal dose real-time monitoring device and method are suitable for intraoperative individual dose collection and dynamic evaluation in the tumor radiotherapy process. The device comprises a flexible attaching substrate, a first measuring range detection sub-module, a second measuring range detection sub-module, a self-adaptive scheduling unit, a temperature compensation module, a breathing synchronous correction module and a wireless communication module. The device can respond to different dose intensities in real time and adaptively switch or fuse channels; the collected dose projection is restored to a planned coordinate system through a breathing phase recognition and target region drift model, and dynamic target region dose tracking is achieved; temperature correction and wireless transmission functions are combined, and intraoperative data visualization and postoperative evaluation are supported. According to the invention, the precision and safety of radiotherapy dose monitoring are improved, and the method is especially suitable for radiotherapy management of areas with significant respiration-induced drift or adjacent key organs.

The invention provides a wireless electronic personal dosimeter capable of dynamically adjusting an alarm threshold value and a control method, and relates to the technical field of radiation monitoring. Comprising a detection module used for collecting historical dose data of a user and constructing a personal dose management library. And the wireless communication module is used for extracting accumulated dose data. And the man-machine interaction module is used for setting a fixed alarm threshold value, setting a personalized alarm threshold value according to the real-time accumulated dose and the accumulated dose data, comparing the fixed alarm threshold value with the personalized alarm threshold value in real time, and selecting a lower value as a real-time alarm triggering standard. And the alarming and updating module is used for judging whether the current dose of the user exceeds a real-time alarming triggering standard, if so, alarming, and uploading the current dose to the personal dose management library for updating. According to the invention, through setting the personalized alarm threshold value, the personal dose accumulation risk can be effectively reduced, the personnel in a low-dose environment for a long time can be more effectively protected, and personalized and precise management of radiation protection is realized.

Microparticulate compositions and methods for delivery and pulsatile release of one or more sting agonists and / or receptors have been developed. The compositions include polymeric microdevices formed from biodegradable and biocompatible polymers or co-polymers thereof including a shell and compartment(s) or discrete regions in the compartment(s) formed by an additive process such as micromolding, three dimensional printing and lithography. The compositions include microdevices that release individual doses of incorporated STING agonist and / or receptors at defined times, for example, in pulses up to several months after administration with essentially no leakage between releases.

The invention relates to a nuclear medicine medication nursing radioactive operation safety warning and evaluation system. The system comprises a sensing acquisition module, a behavior identification module, a dose evaluation module, a risk evaluation module, a risk grade division module, a warning and intervention module, a data storage and tracing module and a self-adaptive learning module. The system can collect parameters such as environment dose rate, individual dose rate, operation distance and time in real time in the processes of nuclear medicine preparation, split charging, injection and waste liquid disposal, analyze operation behaviors of nursing personnel in combination with action recognition results, dynamically calculate accumulated dose, and improve the accuracy of the operation of the nursing personnel. Risk indexes are constructed by comprehensively considering factors such as dosage ratio, liquid medicine residue activity and violation probability, and graded early warning is carried out; when the risk level exceeds a threshold value, triggering acousto-optic and terminal prompt, and generating an operation log for tracing; the system has data storage and self-adaptive optimization functions at the same time, model parameters can be corrected according to historical risk data, and long-term dynamic optimization is achieved.

Disclosed herein are immediate release oral dosage forms that contain abuse-deterrent and abuse-resistant features. In particular, the disclosed dosage forms can provide deterrence of abuse by ingestion of multiple individual doses. The disclosed dosage forms can likewise provide protection from overdose in the event of accidental or intentional ingestion of multiple individual doses. The dosage forms may also exhibit abuse resistant properties when physically manipulated, and also when physically manipulated and then administered in a manner not consistent with oral dosing. The dosage forms may also exhibit abuse resistant properties when administered in a manner intended to result in administration of the esketamine in a higher than therapeutic dose.

1. The name of the design product: personal dosimeter. 2. The use of the design product: the design product is used for monitoring the personal cumulative dose and dose rate caused by X and γ radiation in the nuclear radiation environment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: front view.

The utility model discloses a miniaturized personal dose alarm apparatus, which belongs to the technical field of dose alarm apparatuses and comprises an alarm apparatus body, and an adjustable back clamping mechanism is mounted at the rear end of the alarm apparatus body. The adjustable back clamping mechanism comprises an adjusting assembly and a magnetic attraction assembly, the adjusting assembly is installed at the rear end of the alarm instrument body, and the magnetic attraction assembly is connected with the alarm instrument body and the adjusting assembly; the front end of the alarm apparatus body is provided with a foldable supporting mechanism. Through cooperation of the adjusting assembly and the magnetic attraction assembly, clothes with different thicknesses can be adapted, and an operator can conveniently carry the clothes; when the equipment does not need to be carried, the equipment can be fixed on the metal plate through the magnetic attraction assembly, so that the equipment can be conveniently taken when used next time; the folding supporting mechanism can enable the alarm apparatus body to stably stand on the ground or a platform in a vertical state when detection operation needs to be carried out, so that an operator can conveniently observe data; when the detection operation is not needed, the screen of the alarm apparatus body is protected, and the screen of the alarm apparatus body is prevented from being broken.

The utility model discloses a personal dose monitoring device based on intelligent wearing device, including dosimeter, the dosimeter bottom is equipped with adjustable quick -wearing mechanism, both sides of adjustable quick -wearing mechanism are equipped with connecting seat, be equipped with adjustable wearing mechanism on connecting seat, adjustable quick -wearing mechanism includes base and two embedded blocks, the base top is equipped with adjusting seat, the base inside is opened with movable slot, a plurality of limit posts are fixedly connected on the base inner wall, a plurality of movable round blocks are equipped on the limit post, belong to personal dose monitoring technical field. The personal dose monitoring device based on intelligent wearing device, through embedding the embedded block to the embedding seat, embedded block utilizes the slope and promotes the locking block to remove, and the locking block is locked to the inside of the card slot and is locked, and the convenient quick assembly and disassembly are carried out, and then the angle is adjusted to the adjusting seat, and the operation and use are convenient, thereby can effectively improve the convenience of use.

The utility model provides a pair of glasses and a wearable protection system, and the glasses comprise a glasses frame (100) which is configured to be equipped with lenses (200); the number of the glasses legs (300) is two, and the two glasses legs (300) are respectively arranged at the two ends of the glasses frame (100); a mounting part is arranged on at least one glasses leg (300); and a dose detection device (500), the dose detection device (500) being disposed on the mounting portion, the dose detection device (500) being configured to detect an individual dose. According to the glasses structure, the instrument for detecting the personal dose is arranged on the protective glasses which must be carried by the radiation medical staff in the diagnosis and treatment process, and firstly, the protective glasses are not prone to being ignored; the protective glasses are still located at obvious positions, and if the protective glasses are ignored in the actual use process, other workers can also be reminded. In addition, according to the glasses structure, medical staff do not need to additionally carry a personal dosimeter, and equipment carried by the medical staff is reduced.

The invention discloses an FAPbBr3 crystal-based personal dose device, which comprises an electrode part and a shell part, and compared with a traditional Geiger counter, the FAPbBr3 crystal-based personal dose device can realize accurate measurement in both low-dose and high-dose environments, overcomes the problem of response saturation of the Geiger counter in high-dose environments, improves the detection capability in the low-dose environment, and improves the detection accuracy of the FAPbBr3 crystal-based personal dose device. The FAPbBr3 crystal can distinguish radiation photons with different energies, the requirement for a power supply system is reduced, meanwhile, the overall size and weight of equipment are reduced, and portability is improved. The shell part made of the aluminum alloy material provides physical protection for internal components, and the stability and the reliability in a severe environment are enhanced. When radiation particles or rays penetrate through the FAPbBr3 crystal, radiation energy is directly converted into quantifiable electric signals, then the electric signals are analyzed and recorded through the data processing part, and a more accurate, reliable and high-adaptability personal radiation protection solution is provided.

To reduce a quantity of a member existing on a front side of a case while keeping a function of a clip in a personal dosemeter.SOLUTION: A case includes an enlarged portion 16, a transition part 18, and a main body 20. A radiation sensor is arranged inside the enlarged portion 16. A clip 14 includes a shoulder part 124 and an arm part 126. A base structure 120 and an upright structure 121 are connected by a pin 122. In an attachment state of the clip 14, the shoulder part 124 is pre-deformed by elasticity, and pressing force 140 is applied to a front surface 24 of the case from the clip 14.SELECTED DRAWING: Figure 5

1. The name of the design product: personal dosimeter. 2. The use of the design product: for monitoring the personal cumulative dose and dose rate caused by X, γ radiation. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.

1. Name of the product in this design: Personal Dosimeter. 2. Purpose of this design: For monitoring the personal dose (neutron, X-ray and gamma rays) of radiation workers in nuclear technology applications, to ensure the life, health and safety of personnel. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention provides a pharmaceutical formulation that has 0.5-10 Ci (Curies) total activity of 2-(1-{6-[(2-[F-18]fluoroethyl)(methyl)amino]-2-naphthyl }ethylidene)malononitrile (F-18 Flornaptitril) that is suitable for separation into individual doses for use in medical imaging. The invention also includes a process for preparing Curie-scale pharmaceutical formulations of F- 18 Flornaptitril. The process minimizes radiolytic decomposition during the fluorination reaction to facilitate synthesis of F-18 Flornaptitril pharmaceutical compositions with Curie-scale activity levels.

The present invention provides methods for treating a patient having one or more conditions associated with IFNβ expression in the patient, comprising administering to the patient an anti-IFNβ antibody in a dosing regimen sufficient to ameliorate signs and symptoms of the one or more conditions by at least four weeks after initiation of treatment with the anti-IFNβ antibody, wherein the dosing regimen includes multiple individual doses separated by at least one week from each other, as well as formulations suitable for such methods.

1. The name of the design product: personal dose alarm (HAW-30OM Plus). 2. The use of the design product: radiation measuring instrument for personal radiation dose or radiation dose rate alarm of X, Y, neutron and other rays. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1.

The invention belongs to the technical field of dose management, and particularly relates to a personal dose management system software personnel admission judgment method. The internal and external irradiation dose data are integrated, and when a person wearing the dosimeter enters and exits the control area, the exit reader automatically uploads the external irradiation data to the system. The system supports personnel and RWP information management, information is added in a single entry mode, an Excel batch import mode or an interface butt joint mode, and parameters such as an access state and a dose limit value are configured. A person needs to pass dual verification before entering the control area, wherein the dosimeter needs to meet system registration, non-control state and effective verification. A dose limit value adopts a default or self-defined threshold value, and after multi-level verification, a system side is allowed to enter an operation area to form a complete radiation safety management and control closed loop. The system has the advantages that the system judges the dosimeter information, the personnel information and the RWP information, the control area is allowed to enter when it is ensured that the dosimeter information and the personnel information are registration information in the system, and the safety and reliability of the system are improved.

The present invention is directed to an individual dose pod for use with an automatic brewing machine. The pod includes a cup, at least one pharmaceutical active ingredient, and a lid which seals the pharmaceutical active ingredient inside the cup and provides a barrier against environmental factors.

The present invention relates to a beta radiation personal dose equivalent H p (3) A secondary standard ionization chamber and a quantity transfer method, belonging to the field of metrological measurement technology, comprises the following steps: S1, establishing a physical model of human tissue and a phantom, and obtaining the H of a typical β nuclide under the phantom at an incident angle of ‑45° to +45° by simulation calculation. p (3) / D T Conversion coefficient database; S2, place the ionization chamber under the β radiation field, place the phantom next to the rear end of the ionization chamber, and calculate the corresponding D at the measurement point based on the electrometer current reading T ; S3, according to D T The measurement result is multiplied by the conversion coefficient of the corresponding β nuclide in the database at the corresponding incident angle to obtain H at the measurement point. p (3) The agreed value; S4, placing the monitoring device in the β radiation field, close to the phantom, and achieving value transfer by calculating the relative inherent error, statistical fluctuation, and angular response of the monitoring device. The use of the ionization chamber and value transfer method provided by the present invention can ensure that the measurement results of the radiation monitoring device are accurate and reliable.

1. Name of the product in this design: Radiation Tester (Card-type Personal Dosimeter with β Detection Window). 2. Purpose of this design: Primarily used for testing radiation. 3. The key design feature of this product is its shape. 4. The picture or photo that best illustrates the design points: bottom view.

The invention relates to methods for treating neovascular age-related macular degeneration (nAMD) in a patient, the methods comprising (a) administering to the patient as a loading phase of two individual doses of a VEGF antagonist at 6-week interval (q6w regimen), (b) assessing the patient for disease activity after the second dose of the loading phase, and (c) optionally if presence of disease activity is identified after the second dose of the VEGF antagonist, the method further comprises administering to the patient as part of the loading phase a third dose of the VEGF antagonist 6 weeks after the second dose.

The invention relates to the technical field of medical ring dosimeters, in particular to an operating device of a hand ring dosimeter for external irradiation personal dose monitoring, the operating device fixes the hand ring dosimeter through a mounting assembly, and a disinfection part and an identification generation part are arranged in the operating device. A first sliding seat and a second sliding seat in the operating device are connected with the mounting assembly through a detachable structure; the first sliding seat and the second sliding seat are arranged on the rotating arm in a sliding mode, the rotating arm is supported on the lifting seat in a rotating mode, and the lifting seat is arranged on the lifting driving part. The operation device moves the hand ring dosimeter to the identification generation part, and wearer information is generated on the identification part of the hand ring dosimeter; and the operating device moves the hand ring dosimeter into the disinfection part for soaking and disinfection.

1. Name of the design product: Personal dose alarm (high sensitivity). 2. Use of the design product: For personal dose alarm reminder. 3. Design key points of the design product: Lies in the shape. 4. Picture or photo that best shows the design key points: Perspective view 1.

The utility model provides a pair of glasses and a wearable protection system, and the glasses comprise a glasses frame which is configured to be equipped with lenses and is provided with a mounting part; the number of the glasses legs is two, and the two glasses legs are respectively arranged at the two ends of the glasses frame; and the dose detection equipment is arranged on the mounting part, and the dose detection equipment is configured to detect the individual dose. According to the glasses structure, the instrument for detecting the personal dose is arranged on the protective glasses which must be carried by the radiation medical staff in the diagnosis and treatment process, and firstly, the protective glasses are not prone to being ignored; the protective glasses are still located at obvious positions, and if the protective glasses are ignored in the actual use process, other workers can also be reminded. In addition, according to the glasses structure, medical staff do not need to additionally carry a personal dosimeter, and equipment carried by the medical staff is reduced.

The invention discloses a thermoluminescence personal dose automatic measurement system and method. The system comprises an automatic loading module, an automatic transfer module, an automatic disassembly and assembly module, an automatic annealing module and an automatic analysis module. The automatic sheet loading module is used for loading a dose sheet into a cartridge holder; and a thermoluminescent crystal is arranged in the dosage piece. The automatic transfer module is used for transferring the cartridge holder; the automatic dismounting and mounting module is used for dismounting and mounting the thermoluminescent crystal; the automatic annealing module is used for annealing the thermoluminescent crystal; and the automatic analysis module is used for sorting the annealed thermoluminescent crystals. According to the invention, old crystals in the dosimeter can be automatically split, and meanwhile, new crystals are filled. The whole process is fully automatic, the working efficiency is greatly improved, and the labor cost is reduced.

The invention belongs to the technical field of nuclear power radiation protection, and provides a nuclear power plant personal dose control value prediction method based on deep learning in order to solve the problems that in the prior art, static threshold setting cannot adapt to complex operation scenes, and personalized prediction is lacked. Preprocessing the in-out record data and extracting category features and numeric features to obtain an input feature vector; constructing a multi-modal deep learning model; training the multi-modal deep learning model by using a mean square error loss function; and performing preprocessing and feature extraction on task information of a to-be-predicted worker, and inputting the task information into the trained multi-modal deep learning model to obtain a personal dose control value prediction result of the to-be-predicted worker. According to the method, dynamic and personalized dose prediction can be realized, and the accuracy and safety of radiation protection of the nuclear power plant are remarkably improved.

This invention provides a device and method for real-time monitoring of individual radiation source dose based on a dual-range adaptive mechanism, suitable for intraoperative individual dose acquisition and dynamic assessment during tumor radiotherapy. The device includes a flexible attachment substrate, first and second range detection submodules, an adaptive scheduling unit, a temperature compensation module, a respiratory synchronization correction module, and a wireless communication module. The device can respond in real time to different dose intensities, adaptively switching or merging channels; through respiratory phase recognition and target drift modeling, it projects the acquired dose back to the planning coordinate system, achieving dynamic target dose tracking; and combined with temperature correction and wireless transmission functions, it supports intraoperative data visualization and postoperative assessment. This invention improves the accuracy and safety of radiotherapy dose monitoring, and is particularly suitable for radiotherapy management in areas with significant respiratory-induced drift or near critical organs.

Aspects of the present invention relate to a separate dose package. The individual dose package may include a single portion cartridge and an outer package surrounding the single portion cartridge as a whole and sealing the single portion cartridge therein, wherein the outer package is child resistant and creates an impermeable barrier that prevents the passage of liquids and gases. The single-serving cartridge may include a cup, at least one pharmaceutically active ingredient provided in the cup, and a lid affixed to the cup. The outer package is of a multi-layer structure and comprises a first layer which is a biaxially oriented polyethylene glycol terephthalate layer, a second layer which is a polyethylene layer, a third layer which is an aluminum foil layer and a fourth layer which is an ionomer layer.

An apparatus for discretizing a dose of particles to be placed on a water-soluble substrate, the apparatus comprising a hopper feeder that provides a continuous flow of particles on a belt to a discretization unit wherein the discretization unit in funnel form converts the continuous flow of particles from the feeder system into individual doses, where the individual doses are separated from the feeder system. The particle is received through an inlet and the individual dose is delivered through an individual outlet to a substrate that moves synchronously on a belt within the funnel.