21 results about "Cumulative dose" patented technology

The invention discloses a four-dimensional dynamic image guided dose optimization system for tumor radiotherapy, and belongs to the technical field of medical imaging and radiotherapy. The system comprises a real-time image acquisition module, a dynamic anatomical model construction module, an organ deformation prediction module, a motion compensation engine, a four-dimensional dose accumulation calculation module, a self-adaptive treatment plan generation module and a dose delivery control module. A patient-specific four-dimensional dynamic anatomical model is constructed based on a deep neural network, an autoregression algorithm is adopted to predict organ motion trails, motion compensation parameters are calculated in real time, cumulative dose distribution considering tissue deformation is accurately calculated, a treatment plan is automatically adjusted, and dose delivery with millimeter-level precision is achieved. According to the system, the target area coverage deviation is reduced by 62%, the normal tissue irradiation dose is reduced by 37%, and the precision and safety of thoracic and abdominal tumor radiotherapy are remarkably improved.

The application provides a method and device for monitoring the dose of an X-ray machine, the method comprising: obtaining a functional relationship between the dose rate of the X-ray machine at a preset detection position and the exposure parameter of the X-ray machine when the X-ray machine operates at a preset frame rate; calculating the dose rate at a target detection position when the X-ray machine operates at a target frame rate and a target exposure parameter according to the functional relationship, the distance between the preset detection position and the target detection position relative to the focal point of the X-ray machine tube; calculating the cumulative dose of the X-ray machine at the target detection position according to the dose rate and the exposure time of the X-ray machine; and calculating the cumulative dose-area product of the X-ray machine according to the cumulative dose and the field area of the X-ray machine at the target detection position. The method and device for monitoring the dose of the X-ray machine can realize accurate measurement of the dose rate, cumulative dose and cumulative dose-area product of the X-ray machine through software, can balance low cost and high accuracy dose monitoring, and has a wide range of applications.

This application discloses a three-dimensional dose reconstruction method and related equipment based on in-beam positron emission tomography (PET) data. The method includes: acquiring list-pattern data during proton therapy beam exit; performing conformation processing on the list-pattern data and reconstructing a three-dimensional activity distribution map; performing multi-nucleus dynamic deconvolution processing on the activity time series corresponding to the three-dimensional activity distribution map according to the physical half-life of the target nuclide and preset biological elution parameters to obtain the initial activity distribution corresponding to the target nuclide; mapping the initial activity distribution to a three-dimensional relative dose distribution using a preset dose mapping algorithm; converting the three-dimensional relative dose distribution into a three-dimensional absolute dose distribution according to a pre-established water phantom calibration curve; and generating a cumulative dose distribution report based on the three-dimensional absolute dose distribution. The embodiments of this application can reconstruct the three-dimensional absolute dose distribution with high accuracy and support inter-session dose accumulation analysis. This application can be widely applied in the field of dose reconstruction technology.

1. The name of the design product: personal dosimeter. 2. The use of the design product: the design product is used for monitoring the personal cumulative dose and dose rate caused by X and γ radiation in the nuclear radiation environment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: front view.

The application discloses an anti-radiation sensor, which comprises a sensor body, a base fixedly connected to the bottom of the sensor body, and a sensing surface on the top of the sensor body; and an anti-radiation assembly surrounding the side surface of the sensor body, which comprises, from inside to outside, a heat insulation layer, an anti-radiation layer and a protective shell. The application provides an anti-radiation sensor, which can reduce the influence of external radiation on the sensor by arranging the anti-radiation assembly outside the sensor body, so that the sensor can normally work in a high-dose-rate and high-cumulative-dose radiation environment, and stable operation of the sensor is ensured.

The invention belongs to the technical field of dosimeter calibration, and aims at solving the problems that a traditional dosimeter calibration method depends on manual operation, multi-test-point switching, data recording and off-line calculation need to be completed in a cesium source radiation field, efficiency is low, and test errors are likely to be introduced. According to the dosimeter intelligent calibration method and system based on the multi-modal algorithm, by designing a dual algorithm architecture of a measurement counting mode and an automatic scale mode, autonomous calculation of a gain correction factor and a background correction factor of a dosimeter is achieved, dose accumulation is monitored and stored in real time, and the accuracy of calibration is improved. Through a dynamic switching mechanism of external clock counting and port interruption counting, the stability of a radiation field is accurately judged, the sequential control precision of data acquisition is ensured, real-time calculation and storage of accumulated dose in a multi-gradient dose rate field are realized, and the continuity and traceability of calibration data are ensured. Through full-closed-loop automatic design, the problems of timing error, data input deviation and flow redundancy caused by manual operation are thoroughly eliminated.

The invention discloses a product irradiation monitoring system and method, and relates to the field of product monitoring. The system comprises an irradiation source device, a product conveying device and an environment monitoring unit, and real-time correction is carried out by constructing a voxelization three-dimensional dose rate grid and combining source activity decay and air density parameters; a path integration algorithm is used to calculate a dynamic accumulated dose according to the instantaneous position and speed of the product, and the transmission frequency is adjusted in a closed-loop manner. The system is also integrated with a non-contact dose verification unit based on passive RFID for model calibration, and an excessive radiation estimation and automatic source reduction protection mechanism for a card chain fault. According to the invention, through multi-dimensional environment perception and dynamic integral calculation, the problems of low dose control precision and lack of real-time feedback in traditional irradiation processing are effectively solved, and the stability and safety of product irradiation quality are ensured.

The application provides a wireless electronic personal dosimeter with dynamically adjustable alarm threshold and a control method, and relates to the technical field of radiation monitoring. The application comprises a detection module for collecting historical dose data of a user and constructing a personal dose management library. A wireless communication module is used to extract cumulative dose data. A human-computer interaction module is used to set a fixed alarm threshold, set a personalized alarm threshold according to real-time cumulative dose and cumulative dose data, compare the fixed alarm threshold with the personalized alarm threshold in real time, and select the lower value as the real-time alarm trigger standard. An alarm and updating module is used to judge whether the current dose of the user exceeds the real-time alarm trigger standard, and if so, an alarm is given and the current dose is uploaded to the personal dose management library for updating. The personalized alarm threshold set by the application can effectively reduce the cumulative risk of personal dose, and can more effectively protect personnel who are long-term in a low-dose environment, so as to realize personalized and precise management of radiation protection.

The present application relates to the technical field of vacuum coating, in particular to a rotating-evaporation rate collaborative control method and system based on deposition distribution model, which establishes a deposition process model containing an evaporation source distribution model, a substrate kinematics model and a cumulative dose model; based on the model, a rotating speed ω(t) and an evaporation rate R i (t) are optimized variables, a collaborative control trajectory is generated through multi-objective optimization; the trajectory is executed; and deposition state data is obtained in real time during the coating process, compared with the model prediction value, the model parameters are corrected online and the trajectory is regenerated, realizing rotating-evaporation rate collaborative control. The method first promotes the rotating speed from a fixed parameter to an active control variable, optimizes it collaboratively with the evaporation rate, increases a completely independent control degree of freedom, fundamentally breaks through the uniformity and component precision upper limit of traditional single-variable control, and solves the poor uniformity problem of perovskite photovoltaic components in the prior art.

The application discloses a real-time correction method and correction effect analysis method and system based on an EPID image, relates to the technical field of radiotherapy quality assurance, and comprises the following steps: automatically screening a dose image to obtain a cumulative dose image; positioning four corner points of a distorted field of an electronic portal imaging device (EPID) image to obtain a distorted quadrilateral; defining a target rectangle according to nominal field parameters input by a user; and realizing mapping of the distorted quadrilateral to the target rectangle by using a perspective transformation matrix to complete image correction. The application has high real-time performance, is compatible with FLASH radiotherapy, does not require any manual intervention in the whole process, can simultaneously correct in-plane rotation and X / Y axis tilt of the EPID, and makes up for the fact that existing EPID schemes have low automation degree, need manual intervention and cannot automatically correct perspective distortion, so that the analysis precision is seriously insufficient.

The application discloses a radioactive targeting drug anti-radiation taking system and positioning scheduling method, and relates to the technical field of nuclear medicine radioactive drug management. The method quantifies the activity deviation within the prescription allowable deviation range as a loanable activity balance, establishes an activity deviation account for each patient and reversely solves a permitted taking time window; the method finds the intersection of each taking task to form an initial taking cluster, and realizes the merging of independent tasks which do not enter the initial cluster through activity balance loaning; the method constructs a multi-task merging relationship network, solves a taking scheme which makes the weighted sum of taking frequency and path cost minimum, and outputs a taking instruction. The application converts the drug decay characteristics into scheduling flexibility through the activity balance loaning mechanism, reduces the taking operation frequency and the moving path, and controls the cumulative dose of the patient within the prescription allowable range through the closed-loop management of the deviation account.

The invention discloses an electronic personal dosimeter applied to a medical intervention pulse radiation field, and relates to the field of medical radiation monitoring, and the electronic personal dosimeter comprises an instantaneous-accumulation dual-channel detector, an ADC, a main controller and a segment code screen; the detector is arranged in the medical intervention pulse radiation field, is connected with the ADC and is used for simultaneously collecting transient response current and accumulated integral charge of the medical intervention pulse radiation field; the ADC is connected with the SPI end of the main controller; the LCD end of the main controller is connected with the segment code screen; the transient response current and the accumulated integral charge of the radiation field are synchronously collected through the detector and are converted into digital signals through the ADC, and after the radiation dose rate and the radiation accumulated dose are calculated by the main controller, the radiation dose rate and the radiation accumulated dose are displayed in real time through the segment code screen. The radiation dose rate and the radiation accumulated dose of the detector can be synchronously monitored in real time in a small size by adopting a dual-channel combination mode, the power consumption is reduced, and the portability and the environmental adaptability of the dosimeter are improved.

This invention discloses a treatment plan optimization method and related equipment based on deterministic coupling of respiratory motion, relating to the field of radiotherapy technology. The method includes: acquiring multi-temporal 4DCT sequences of the patient and corresponding respiratory motion curves; constructing a mapping relationship between respiratory phase and organ position; establishing a dynamic coupling mapping relationship between beam spot triggering time, respiratory phase, and anatomical position; constructing a 4D dose simulator based on the dynamic coupling mapping relationship to simulate the treatment plan and output a 4D cumulative dose distribution; comparing the 4D cumulative dose distribution with a preset clinical target, and if the error exceeds the tolerance range, activating an intelligent optimizer for optimization until the 4D cumulative dose distribution meets clinical requirements, and outputting the current treatment plan; achieving precise quantification and individualized adaptive compensation of the impact of respiratory motion, improving the realism of proton therapy dose deposition, the robustness of target coverage, and the optimization efficiency of the treatment plan.

This application relates to an electron linear acceleration and irradiation method based on a solid-state power source, comprising: the extracted electron beam passes through the guiding and focusing elements in the beam transmission system and reaches the irradiation area; along this path, key parameters of the electron beam are monitored in real time using a beam diagnostic device, including at least beam energy, current intensity, and beam spot position information; the material to be irradiated is placed in the irradiation area and receives scanning irradiation from the electron beam; simultaneously, dose monitoring sensors deployed in the irradiation area or within the material are used to acquire absorbed dose rate or cumulative dose distribution information in real time; throughout the acceleration and irradiation process, the central controller synchronously records timestamp-correlated historical data of beam parameters, power source adjustment commands, dose monitoring data, and material identification information to obtain a complete and traceable electron beam irradiation process archive.

The application discloses a data conversion and output method and system for CANDU reactor radiation dose simulation, relates to the technical field of nuclear engineering safety analysis and computer simulation, and comprises the following steps: obtaining original dose data in the unit of (Sv / s) / (Bq / m3) in a nuclear safety analysis report, automatically converting the original dose data into dose conversion factors in the unit of (Sv / s) / (individual / m3) based on a decay constant, and performing working condition adaptability correction on the dose conversion factors in combination with at least one of heavy water moderation characteristics, horizontal pressure tube geometric effects and double-loop asymmetric source term distribution characteristics to obtain corrected dose conversion factors; simulating the total number of captured radionuclide atoms, multiplying the total number of captured radionuclide atoms by the corrected dose conversion factors after volume standardization to obtain an instantaneous dose rate, and then performing time integration on the instantaneous dose rate to obtain a cumulative dose, and automatically converting the cumulative dose into an mSv order output, so that the calculation efficiency, simulation accuracy and engineering usability are significantly improved.

The invention relates to an indoor environment radioactivity simulation measurement system based on LiDAR / IMU fusion positioning. The indoor environment radioactivity simulation measurement system comprises: 1, a laser radar and an inertial measurement unit; the simulation detector module is used for detecting virtual radioactive contamination data in an environment coordinate system; the calculation module is used for calculating the position parameters of the positioning module, obtaining the space coordinate position of the positioning module and obtaining the actual position of the analog detector; and 4, a radioactivity measurement data resolving module for resolving radioactivity measurement data such as the dose rate and the accumulated dose value of the position where the detector is located according to the position, the area and the activity parameters of the contamination point in the virtual nuclear radiation environment construction. The system has the advantages that 1, radioactive measurement training can be carried out in an indoor environment without GPS signals or with unsmooth reception by utilizing the system, the problem of positioning loss does not exist, the system is not limited by sites, and nuclear radiation reconnaissance task training can be carried out in any area;

The invention relates to a 3D printing device and method based on rotating X-rays, and the printing device comprises an X-ray generation module which is used for outputting an X-ray beam; the rotary resin container system is used for containing an X-ray curable material and rotating around the central axis of the rotary resin container system; the X-ray mask assembly is used for shaping the X-ray beam into a two-dimensional projection pattern corresponding to the rotation angle of the rotary resin container system, so that the two-dimensional projection pattern sequentially accumulates doses in different circumferential areas of the X-ray curable material; the dose monitoring module is used for collecting the X-ray dose after the X-ray curing material passes through the X-ray curing material in real time and outputting a dose feedback signal; the control system is used for adjusting the power and / or irradiation time of the X-ray source in real time until the accumulated dose of the target area reaches a threshold value, so that the X-ray curable material is cured into a three-dimensional object, and the adaptation range of the material can be greatly widened; the forming quality and the size precision of the part are improved, the biocompatibility is improved, and printing of the biomedical implant containing living cells can be achieved.

A method and system for determining the value and associated uncertainty of time-cumulative quantities as part of a patient-specific dosimetry in radiopharmaceutical therapy (RPT), is described. The method comprising: obtaining a dataset comprising of one or more dosimetric quantity data values and associated uncertainties at one or more timepoints each representing a quantity of dosimetric interest associated with at least one radiopharmaceutical agent present within a volume of the patient; selecting a dosimetric quantity time representation curve (TRC) model comprised of one or more curves which contiguously span from the time of administration of the radiopharmaceutical; determining one or more parameters associated with at least one of the one or more curves comprising the selected TRC model where each of the one or more curves is directly calculated from the dosimetric quantity data values; determining from the one or more curves a mathematical function which directly relates the time cumulative quantity to the dosimetric quantity data values; calculating the cumulative dosimetric quantity data value using the mathematical function; calculating the uncertainty associated with the cumulative dosimetric quantity data value using the mathematical function by a method of propagation of uncertainty; and returning the cumulative dosimetric quantity data value and associated uncertainty as an output.

The invention discloses a real-time correction method based on an EPID image, and a correction effect analysis method and system, and relates to the technical field of radiotherapy quality assurance, and the method comprises the steps: automatically screening a dose image, and obtaining a cumulative dose image; positioning four angular points of an image distortion radiation field of the EPID to obtain a distortion quadrangle; and defining a target rectangle according to nominal radiation field parameters input by a user, and realizing mapping from the distorted quadrangle to the target rectangle by adopting a perspective transformation matrix to complete image correction. The method is high in real-time performance and compatible with FLASH radiotherapy, no manual intervention is needed in the whole process, in-plane rotation and X / Y axis inclination of the EPID can be corrected at the same time, and the defects that an existing EPID scheme is low in automation degree and needs manual intervention, and analysis precision is seriously insufficient due to the fact that perspective distortion cannot be automatically corrected are overcome.

1. The name of the design product: Dose rate watch (x / γ). 2. The use of the design product: Measure x, γ dose rate in the environment and objects, cumulative dose, while integrating clock, motion monitoring, heart rate, blood oxygen, sleep, compass, satellite time service and other functions. 3. The design points of the design product: The combination of shape and pattern. 4. The picture or photo that best indicates the design points: Perspective view 1.

This disclosure provides a dose compensation method and electronic device for adaptive radiotherapy. The method includes: within the i-th fraction of radiotherapy, determining the k-th cumulative dose deviation of the target area under-radiated within the k-th continuous beam exit segment and before the k+1-th continuous beam exit segment; wherein the i-th fraction of radiotherapy is the i-th fraction of I fractions of radiotherapy, where i is 1, 2, 3, ..., I; the k-th continuous beam exit segment is the k-th continuous beam exit segment of K continuous beam exit segments within the i-th fraction of radiotherapy, where k is 1, 2, 3, K; compensating for the k-th cumulative dose deviation within the k+1-th continuous beam exit segment, and / or compensating for the k-th cumulative dose deviation within the i+1-th fraction of radiotherapy.