51 results about "Cumulative dose" patented technology

The invention discloses an intelligent remote follow-up visit method and system for tumor patients, and relates to the technical field of medical intellectualization, and the method comprises the steps: collecting follow-up visit data through a remote medical terminal, carrying out the processing of the follow-up visit data, obtaining a physical sign index sequence and a symptom feature vector, and generating a dynamic follow-up visit evaluation score through a time sequence prediction model; performing semantic analysis on the electronic medical record data of the patient based on the medical knowledge map, extracting tumor stage classification data, chemoradiotherapy measurement data, weight nutrition indexes and laboratory inspection data, determining a basic risk coefficient, a cumulative dose ratio and a body state score, and generating a baseline follow-up assessment score through a prediction model; and according to the dynamic follow-up evaluation score and the baseline follow-up evaluation score, calculating a comprehensive follow-up grade and generating a next follow-up plan. According to the invention, the accuracy of patient state evaluation is improved, accurate configuration of medical resources is realized, and the quality and efficiency of remote follow-up visit are effectively improved.

Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include operations comprising: obtaining, during delivery of a radiotherapy treatment fraction to a patient, one or more images of the patient at a first rate; generating patient motion information at a second rate based on the one or more images obtained at the first rate; receiving, during delivery of the radiotherapy treatment fraction, radiotherapy treatment device settings at a third rate; computing, during delivery of the radiotherapy treatment fraction, dose delivered to the patient with a first level of accuracy based on the generated patient motion information and the radiotherapy treatment device settings; and determining, during delivery of the radiotherapy treatment fraction, a real-time measure of accumulated dose delivered to the patient with a second greater level of accuracy than the first level of accuracy using one or more prior dose computations.

The invention belongs to the technical field of medical treatment, and discloses a radiotherapy protection system for reducing normal tissue damage, and the system comprises a real-time imaging and monitoring module which employs high-speed CT or MRI equipment to obtain 4D images of a target region and surrounding tissues of a patient in real time in a treatment process; the dynamic protection dose distribution module is used for dynamically calculating dose distribution of each radiation according to the real-time imaging data, optimizing an irradiation path and reducing the stress of normal tissues; the intelligent feedback control module is used for detecting the accumulated dose of a target region and normal tissues in real time and dynamically adjusting an irradiation strategy; inputting the real-time image and the dose monitoring data into a treatment planning system, and updating an irradiation plan; the user interaction module provides a radiotherapy real-time display interface; patient physiological data is monitored in real time. According to the invention, through dynamic real-time monitoring, dose distribution optimization and intelligent feedback control, the limitation of the traditional radiotherapy technology on real-time performance and protection effect is broken through. The system significantly reduces damage to normal tissues, improves treatment precision and patient experience, and has wide clinical application value.

The invention discloses an X-ray machine inspection parameter automatic configuration system for pet inspection, and relates to the technical field of medical imaging equipment, a displacement prediction model is used for pre-judging a pet convulsion state before exposure, a dynamic exposure trigger is only activated in a stable interval, and motion blur is avoided from the source; compared with the scheme of relying on post-exposure image feedback adjustment in the prior art, invalid radiation and repeated exposure operation can be avoided; the partition parameter mapping module is combined with a species feature database to map the gray level of the preview image into equivalent thickness and independently generate region parameters; aiming at extreme body type difference, such as an abdominal fat layer of an obese dog and a rib region of an emaciated cat, the system automatically distributes differentiated kV / mA parameters, and the problem of overexposure or underexposure caused by a traditional fixed penetration rate standard is eliminated; and the radiation fusing unit monitors the accumulated dose in real time, dynamically adjusts a safety threshold according to the weight of the pet, and stops exposure before the dose exceeds the limit.

The invention discloses a close-range radiotherapy plan optimization method and device based on a cumulative dose target. The method comprises the following steps: S1, importing current treatment data; s2, leading in a preorder treatment image and performing deformation registration to the current image; s3, mapping the preorder treatment dose to the current treatment image to serve as the background dose of the current treatment; s4, converting the dose data mapped to the current treatment image by the preorder treatment into a bioequivalent dose; s5, on the basis of the sketching data of the current treatment image and with reference to the clinical endangered organ dose limit value requirement, key area generation is carried out on each endangered organ; s6, based on the preorder treatment dosage, generating a corresponding organ-endangered high-risk dosage area and a target area insufficient area according to each organ-endangered dosage limit value and the target area prescription dosage; and S7, optimizing the treatment plan, and optimizing the treatment plan by taking the preorder treated dose and the sum of the planned dose to be optimized at the time to meet the clinical requirement as a target.

Systems, methods, and computer software relating to gating using non-parallel imaging planes, determining accumulated dose to tissues during radiotherapy with actual beam delivery information, stopping / adjusting / reoptimizing therapy based on such accumulated doses and the generation and use of prognostic motion models and prognostic-motion adapted radiation treatment plans are disclosed.

The invention provides a radioactive biological experimental facility radiation environment monitoring and personal dose monitoring method, which comprises a fixed radiation dose monitor, a portable radiation dose monitor, a personal dose instrument, an experimental facility computer system docking port, an analysis center and an early warning judgment module, the experimental facility environment radiation dose can be monitored in real time, single-time operation personal cumulative doses under three different conditions can be obtained through an experimental facility computer system, radiation dose summary analysis can be carried out on radioactive sources operated in the experimental facility, radiation dose changes under different radioactive source operations are obtained, and the experimental facility environment radiation dose monitoring system can be used for monitoring the experimental facility environment radiation dose in real time. And finally, performing early warning according to the environmental radiation dose and the individual accumulated dose result. The environment radiation state can be monitored timely, accurately and effectively, and the external irradiation dose of personnel can be monitored and evaluated in real time.

The invention discloses a three-dimensional in-vivo radiotherapy dose monitoring method and system, and the method comprises the steps: collecting an image sequence {In} containing time dimensions at a theta t time interval through CBCT scanning equipment in a radiotherapy process; calculating target area displacement of adjacent frames of images in the image sequence {In} by using a bidirectional optical flow estimation method; state estimation and prediction are carried out on the displacement data based on an adaptive Kalman filtering algorithm, a dynamic displacement rule of the target area in the respiratory cycle is generated, and a respiratory movement prediction result is output; acquiring radiotherapy plan parameters from a radiotherapy plan system, and calculating planned dose distribution without considering respiratory movement; dynamically adjusting a ray transmission path and energy deposition according to a respiratory movement prediction result, and calculating real-time dose distribution of each respiratory time phase; mapping the dose distribution of each time phase to a reference time phase coordinate system to generate accumulated dose distribution; and comparing and verifying the accumulated dose distribution and the planned dose distribution.

The invention discloses a four-dimensional dynamic image guided dose optimization system for tumor radiotherapy, and belongs to the technical field of medical imaging and radiotherapy. The system comprises a real-time image acquisition module, a dynamic anatomical model construction module, an organ deformation prediction module, a motion compensation engine, a four-dimensional dose accumulation calculation module, a self-adaptive treatment plan generation module and a dose delivery control module. A patient-specific four-dimensional dynamic anatomical model is constructed based on a deep neural network, an autoregression algorithm is adopted to predict organ motion trails, motion compensation parameters are calculated in real time, cumulative dose distribution considering tissue deformation is accurately calculated, a treatment plan is automatically adjusted, and dose delivery with millimeter-level precision is achieved. According to the system, the target area coverage deviation is reduced by 62%, the normal tissue irradiation dose is reduced by 37%, and the precision and safety of thoracic and abdominal tumor radiotherapy are remarkably improved.

Disclosed are systems, methods, and computer software related to gate control using non-parallel imaging planes, determining the accumulated dose to tissue during radiation therapy using actual beam delivery information, stopping / modifying / re-optimizing treatment based on the accumulated dose, and generating and using radiation therapy plans with prognostic motion models and prognostic motion adaptation.

The application provides a method and device for monitoring the dose of an X-ray machine, the method comprising: obtaining a functional relationship between the dose rate of the X-ray machine at a preset detection position and the exposure parameter of the X-ray machine when the X-ray machine operates at a preset frame rate; calculating the dose rate at a target detection position when the X-ray machine operates at a target frame rate and a target exposure parameter according to the functional relationship, the distance between the preset detection position and the target detection position relative to the focal point of the X-ray machine tube; calculating the cumulative dose of the X-ray machine at the target detection position according to the dose rate and the exposure time of the X-ray machine; and calculating the cumulative dose-area product of the X-ray machine according to the cumulative dose and the field area of the X-ray machine at the target detection position. The method and device for monitoring the dose of the X-ray machine can realize accurate measurement of the dose rate, cumulative dose and cumulative dose-area product of the X-ray machine through software, can balance low cost and high accuracy dose monitoring, and has a wide range of applications.

This application discloses a three-dimensional dose reconstruction method and related equipment based on in-beam positron emission tomography (PET) data. The method includes: acquiring list-pattern data during proton therapy beam exit; performing conformation processing on the list-pattern data and reconstructing a three-dimensional activity distribution map; performing multi-nucleus dynamic deconvolution processing on the activity time series corresponding to the three-dimensional activity distribution map according to the physical half-life of the target nuclide and preset biological elution parameters to obtain the initial activity distribution corresponding to the target nuclide; mapping the initial activity distribution to a three-dimensional relative dose distribution using a preset dose mapping algorithm; converting the three-dimensional relative dose distribution into a three-dimensional absolute dose distribution according to a pre-established water phantom calibration curve; and generating a cumulative dose distribution report based on the three-dimensional absolute dose distribution. The embodiments of this application can reconstruct the three-dimensional absolute dose distribution with high accuracy and support inter-session dose accumulation analysis. This application can be widely applied in the field of dose reconstruction technology.

One or more example embodiments relates to a computer-implemented method for dose control with an automatic exposure control. The method comprises receiving a first time-course, receiving a second time-course, and receiving a cut-off dose. The method comprises determining a first weight, determining a second weight, multiplying a latest value of the first time-course with the first weight, wherein a first weighted accumulated dose is determined and multiplying a latest value of the second time-course with the second weight, wherein a second weighted accumulated dose is determined. The method comprises adding the first and the second weighted accumulated dose, wherein a weighted overall applied dose is determined, comparing the weighted overall applied dose with the cut-off dose, and providing a result of the comparison.

Disclosed herein are methods for radiotherapy treatment plan optimization for irradiating one or more target regions using both an internal therapeutic radiation source (ITRS) and an external therapeutic radiation source (ETRS). One variation of a method comprises iterating through ITRS radiation dose values and ETRS radiation dose values to attain a cumulative dose that meets prescribed dose requirements. In some variations, an ITRS is an injectable compound that has a targeting backbone and a radionuclide, and images acquired using an imaging compound that has the same targeting backbone as the injectable compound can be used to calculate the radiation dose deliverable using the injectable ITRS, and also to calculate firing filters for delivering radiation using a biologically-guided radiation therapy (BGRT) system. Image data acquired from a previous treatment session may be used to adapt the dose provided by an ITRS and / or ETRS for a future treatment session.

1. The name of the design product: personal dosimeter. 2. The use of the design product: the design product is used for monitoring the personal cumulative dose and dose rate caused by X and γ radiation in the nuclear radiation environment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: front view.

Provided is a mechanism for enabling a radiation generation apparatus to accurately perform control processing to stop irradiation of radiation. The mechanism includes a dose calculation unit that calculates a cumulative dose of radiation detected by a sensor unit from start of imaging, a timer unit that measures an irradiation time for radiation from a predetermined timing, a threshold decision unit that sets an irradiation stop threshold based on the irradiation time, a control unit including a threshold determination unit that transmits an irradiation stop signal to stop irradiation of radiation to the radiation generation apparatus when the cumulative dose reaches the irradiation stop threshold, and a sensor unit that detects radiation from the radiation generation apparatus. When the dose calculation unit calculates the cumulative dose having reached a predetermined amount from start of imaging, the threshold determination unit causes the timer unit to start measurement of the irradiation time.

The application discloses an anti-radiation sensor, which comprises a sensor body, a base fixedly connected to the bottom of the sensor body, and a sensing surface on the top of the sensor body; and an anti-radiation assembly surrounding the side surface of the sensor body, which comprises, from inside to outside, a heat insulation layer, an anti-radiation layer and a protective shell. The application provides an anti-radiation sensor, which can reduce the influence of external radiation on the sensor by arranging the anti-radiation assembly outside the sensor body, so that the sensor can normally work in a high-dose-rate and high-cumulative-dose radiation environment, and stable operation of the sensor is ensured.

The invention belongs to the technical field of dosimeter calibration, and aims at solving the problems that a traditional dosimeter calibration method depends on manual operation, multi-test-point switching, data recording and off-line calculation need to be completed in a cesium source radiation field, efficiency is low, and test errors are likely to be introduced. According to the dosimeter intelligent calibration method and system based on the multi-modal algorithm, by designing a dual algorithm architecture of a measurement counting mode and an automatic scale mode, autonomous calculation of a gain correction factor and a background correction factor of a dosimeter is achieved, dose accumulation is monitored and stored in real time, and the accuracy of calibration is improved. Through a dynamic switching mechanism of external clock counting and port interruption counting, the stability of a radiation field is accurately judged, the sequential control precision of data acquisition is ensured, real-time calculation and storage of accumulated dose in a multi-gradient dose rate field are realized, and the continuity and traceability of calibration data are ensured. Through full-closed-loop automatic design, the problems of timing error, data input deviation and flow redundancy caused by manual operation are thoroughly eliminated.

The invention discloses a particle three-dimensional dose distribution online reconstruction method, device and equipment and a medium, and aims to improve the particle ray irradiation accuracy and solve the problem that a planned dose is inconsistent with an actual dose. The method comprises the following steps: according to voxel information, treatment plan information and each irradiation point, determining three-dimensional dose distribution dij of a determined irradiation particle number under different conditions, and online acquiring an online irradiation particle number of each irradiation point i measured by a dose monitoring ionization chamber or an irradiation parameter wi in a proportional relation with the particle number; three-dimensional dose distribution Dj of the irradiation point i is reconstructed online according to dij and wi obtained through matching, accumulated dose distribution Djsum is obtained, and the accumulated dose distribution Djsum is displayed in real time through accumulated three-dimensional dose distribution and a dose volume histogram; accumulated three-dimensional dose distribution, target area and attention organ dose volume histograms can be visually displayed on line, the real-time three-dimensional dose of each irradiation point can be checked, the accumulated irradiation dose can also be checked, and the judgment accuracy of an operator is improved.

The invention discloses a product irradiation monitoring system and method, and relates to the field of product monitoring. The system comprises an irradiation source device, a product conveying device and an environment monitoring unit, and real-time correction is carried out by constructing a voxelization three-dimensional dose rate grid and combining source activity decay and air density parameters; a path integration algorithm is used to calculate a dynamic accumulated dose according to the instantaneous position and speed of the product, and the transmission frequency is adjusted in a closed-loop manner. The system is also integrated with a non-contact dose verification unit based on passive RFID for model calibration, and an excessive radiation estimation and automatic source reduction protection mechanism for a card chain fault. According to the invention, through multi-dimensional environment perception and dynamic integral calculation, the problems of low dose control precision and lack of real-time feedback in traditional irradiation processing are effectively solved, and the stability and safety of product irradiation quality are ensured.

The invention relates to the technical field of nuclear radiation detection, in particular to a negative feedback dose rate measurement method, which is based on a quasi-real-time dose rate measurement device adopting a pulsed light luminescence technology, and comprises the following steps: firstly, determining parameters such as photomultiplier dark count, inherent background, accumulated dose, counting conversion coefficient, dose loss factor and the like of the measurement device; and writing an inherent parameter serving as a measuring device into an equipment memory, and continuously measuring the dose rate subsequently to obtain the average dose rate between the current measurement and the last measurement. The accumulated dose loss caused by each dose rate measurement is effectively and accurately compensated, the negative feedback characteristic is achieved, continuous multiple measurement can be achieved after the measurement device is annealed, the measurement error of the measurement device cannot be degraded along with increase of the continuous measurement times, and frequent long-time annealing treatment is not needed; various dynamic and static backgrounds are considered, background deduction is comprehensive and accurate, and the dose rate measurement value is high in accuracy.

The application provides a wireless electronic personal dosimeter with dynamically adjustable alarm threshold and a control method, and relates to the technical field of radiation monitoring. The application comprises a detection module for collecting historical dose data of a user and constructing a personal dose management library. A wireless communication module is used to extract cumulative dose data. A human-computer interaction module is used to set a fixed alarm threshold, set a personalized alarm threshold according to real-time cumulative dose and cumulative dose data, compare the fixed alarm threshold with the personalized alarm threshold in real time, and select the lower value as the real-time alarm trigger standard. An alarm and updating module is used to judge whether the current dose of the user exceeds the real-time alarm trigger standard, and if so, an alarm is given and the current dose is uploaded to the personal dose management library for updating. The personalized alarm threshold set by the application can effectively reduce the cumulative risk of personal dose, and can more effectively protect personnel who are long-term in a low-dose environment, so as to realize personalized and precise management of radiation protection.

The present application relates to the technical field of vacuum coating, in particular to a rotating-evaporation rate collaborative control method and system based on deposition distribution model, which establishes a deposition process model containing an evaporation source distribution model, a substrate kinematics model and a cumulative dose model; based on the model, a rotating speed ω(t) and an evaporation rate R i (t) are optimized variables, a collaborative control trajectory is generated through multi-objective optimization; the trajectory is executed; and deposition state data is obtained in real time during the coating process, compared with the model prediction value, the model parameters are corrected online and the trajectory is regenerated, realizing rotating-evaporation rate collaborative control. The method first promotes the rotating speed from a fixed parameter to an active control variable, optimizes it collaboratively with the evaporation rate, increases a completely independent control degree of freedom, fundamentally breaks through the uniformity and component precision upper limit of traditional single-variable control, and solves the poor uniformity problem of perovskite photovoltaic components in the prior art.

The invention discloses a design method and equipment for a radiation shielding lightweight material of an aerospace electronic component, and a readable storage medium, and relates to the field of aerospace materials. The design method comprises the following steps: determining that the radiation shielding material is of a multi-layer composite structure; the total mass thickness of the radiation shielding material is designed to be lower than the equivalent mass thickness of an Al plate under the same shielding performance; designing a spacecraft equivalent model; gradually adjusting the number of layers of the designed radiation shielding material, the atomic number of each layer, the occupied mass thickness and the stacking sequence, and performing numerical simulation by adopting a Monte Carlo method; the average energy deposition of the silicon balls in the equivalent model of the spacecraft and the cumulative total dose of the total radiation quantity in 10 years are simulated and calculated, and then a radiation shielding material is selected according to the anti-radiation requirement. According to the shielding material designed through the method, the shielding efficiency is improved, and the quality of the shielding material is controlled; and electronic components in the spacecraft can be protected from being subjected to less accumulated dose in the on-orbit working time.

The present invention relates to a method for assessing human radiation dose during nuclear facility decommissioning. The method utilizes a dose assessment system, wherein the dose assessment system is used to assess the human radiation dose during nuclear facility decommissioning operations based on a three-dimensional scene model and radiation field model invoked by the system. The method is characterized in that the dose assessment method comprises the following steps: scanning the position information of the current equipment to obtain coordinate data of the currently operated equipment and operators; invoking the three-dimensional scene model and radiation field model based on the coordinate data of the operated equipment; obtaining nuclear facility disassembly and assembly information during the nuclear decommissioning operation to correct the three-dimensional scene model and radiation field model; and calculating the real-time and cumulative doses received by the operators based on the corrected radiation field model.

The invention relates to a radiotherapy prescription execution rate evaluation method and device. The method comprises the following steps: acquiring image data of a patient; acquiring a radiotherapy prescription and a radiotherapy plan, wherein the radiotherapy prescription comprises a target region prescription dose; after the radiotherapy plan is executed, actual irradiation parameters of each irradiation time are obtained; determining the actual dose distribution of each irradiation fraction based on the patient image data and the actual irradiation parameter of each irradiation fraction; determining the actual dose of the target region based on the actual dose distribution of each irradiation fraction; and determining a radiotherapy prescription execution rate based on the target region prescription dose and the target region actual dose. According to the method and the device for evaluating the implementation rate of the radiotherapy prescription, the cumulative dose of the patient after the radiotherapy plan is completed can be evaluated, and an important reference basis is provided for clinic.

The invention aims to provide a low-energy neutron cumulative dose measurement method, and relates to the technical field of neutron radiation measurement, a natural boron nitride converter is preposed on a CR-39 track sheet, and the response of a BC detector to low-energy neutrons is effectively expanded; the optimal chemical etching condition for independently identifying the low-energy neutron track is determined through a neutron irradiation experiment, so that the measurement precision of the low-energy neutron cumulative dose is greatly improved; the detector has high sensitivity to low-energy neutron response and is linear to the low-energy neutron response, and according to the scale coefficient, after the track density of the low-energy neutrons irradiated by the BC detector is observed, the corresponding low-energy neutron < lt > is calculated; 100keV) accumulated dose equivalent, so that the purpose of independently measuring the low-energy neutrons is achieved.

1. The name of the design product: personal dosimeter. 2. The use of the design product: for monitoring the personal cumulative dose and dose rate caused by X, γ radiation. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.

The application discloses a real-time correction method and correction effect analysis method and system based on an EPID image, relates to the technical field of radiotherapy quality assurance, and comprises the following steps: automatically screening a dose image to obtain a cumulative dose image; positioning four corner points of a distorted field of an electronic portal imaging device (EPID) image to obtain a distorted quadrilateral; defining a target rectangle according to nominal field parameters input by a user; and realizing mapping of the distorted quadrilateral to the target rectangle by using a perspective transformation matrix to complete image correction. The application has high real-time performance, is compatible with FLASH radiotherapy, does not require any manual intervention in the whole process, can simultaneously correct in-plane rotation and X / Y axis tilt of the EPID, and makes up for the fact that existing EPID schemes have low automation degree, need manual intervention and cannot automatically correct perspective distortion, so that the analysis precision is seriously insufficient.

One or more example embodiments relates to a computer-implemented method for dose control with an automatic exposure control. The method comprises receiving a first time-course, receiving a second time-course, and receiving a cut-off dose. The method comprises determining a first weight, determining a second weight, multiplying a latest value of the first time-course with the first weight, wherein a first weighted accumulated dose is determined and multiplying a latest value of the second time-course with the second weight, wherein a second weighted accumulated dose is determined. The method comprises adding the first and the second weighted accumulated dose, wherein a weighted overall applied dose is determined, comparing the weighted overall applied dose with the cut-off dose, and providing a result of the comparison.