35results about How to "Does not cause inflammation" patented technology

The invention relates to a preparation method of developing polyurethane, which pertains to the technical field of high polymer material. The preparation method comprises the steps that: firstly, polymers, diatomic alcohol and diisocyanate are mixed; the mixture of the diatomic alcohol and the diisocyanate is stirred and reacts under the protection of nitrogen gas to obtain a prepolymer; after the temperature thereof is raised, the prepolymer is added with a chain extender and stirred for reaction; and the polymers are cured. As the chain extender contains developing atoms and developing groups are connected with the polyurethane by the effect of chemical bonds, the developing polyurethane prepared by the preparation method has long lasting development effect, good stability, biocompatibility and anticoagulant performance, arouses no inflammation in human bodies, is biological aging resistant and animalcule resistant, has good physical properties, can be sterilized by usual methods, is easy to be processed and takes advantages over non-developing polyurethane when being applied to heart valves, conduits and vascular stents. The preparation method is flexible, effective, simple andeasy to be realized.

The invention relates to an injectable temperature sensitive gel used for filling and repairing damaged tissues. The gel is characterized in that: medical-grade hyaluronic acid and chitosan are used as gel raw materials; the gel swelling ratio is 2-500; and a temperature sensitive temperature is 32-37 DEG C. The gel provided by the invention has the advantages that the injection temperature sensitive gel has physical and chemical properties of a general gel, also has injectable and temperature sensitive properties and a good fluidity at a room temperature and is easy for injection; the formability in organisms is good and the degradation is slow so that the general gel can not be compared; a cross-linking agent is not used for the gel so that harms of the cross-linking agent to a human body are avoided; a gel system can prolong a persistence time of the gel in a body, and also can continuously stimulate the body to produce reactions so that the tissue in-situ regeneration and repair is promoted and the filling quality is increased; and the gel simultaneously has the advantages of reducing bacterial invansion, anticoagulation and low allergic reaction and the like.

The present invention relates to a liquid-absorbing material, in particular to a method for preparing a skin-friendly liquid-absorbing material. The preparation method comprises the following steps: 1) modifying β-cyclodextrin by introducing a double bond; 2) modifying β-cyclodextrin and hydroxypropyl-β-cyclodextrin with different Ds are dissolved in lye; 3) adding monomer and initiator to the mixed solution in step 2) for pre-crosslinking; 4) increasing drop by drop Add the sodium alginate solution dropwise to the reaction solution in step 3) to continue cross-linking; 5) keep it warm and dry it. The skin-friendly liquid-absorbent material prepared according to the method of the present invention is friendly to the skin, does not irritate the skin, does not cause adhesion after contact with the skin, does not cause inflammation, has relatively excellent liquid-absorbent performance, and has satisfactory Mechanical effect, its degradability is excellent, and it is friendly to the environment.

The invention relates to a use of human amniotic epithelial cells (hAECs) in treatment of graft-versus-host disease (aGVHD). The invention discloses a method for treating and / or improving the graft-versus-host disease by using effective dose of the amniotic epithelial cells or a cell preparation containing the amniotic epithelial cells alone or in combination with other drugs. The amniotic epithelial cells can be given to patients by intravenous injection or intramedullary injection, the dosage range given at each time is about 10<3>-10<9> cells, the infiltration of inflammation cells caused by aGVHD to target organs can be effectively alleviated, the lesion of target organs is also significantly alleviated, the hAECs are found out to have an apoptosis-promoting effect on multiple leukemiacell lines and be used for treating the graft-versus-host disease.

It is intended to provide a composition containing, as the active ingredient, retinoic acid nanoparticles having relieved irritation, which can be subcutaneously and intravenously administered, is usable as a sustained release preparation, and has such a high skin-permeability as allowing the use thereof as an external preparation such as a drug or a quasi drug as well as a cosmetic to be applied to the skin, etc. When dissolved in water, the retinoic acid nanoparticles coated with a polyvalent metal inorganic salt, i.e., the active ingredient, are maintained in the form of a transparent solution and, therefore, can be administered as a subcutaneous or intravenous injection. Since retinoic acid is coated with a polyvalent metal inorganic salt film, these nanoparticles are characterized by showing relieved irritation and thus causing neither inflammation nor canceration at administration site. As the polyvalent metal inorganic salt, use is made of calcium carbonate, zinc carbonate or calcium phosphate.

An earring that can be easily put on an ear without coming off during a use thereof and causes no pains in the earlobe of the ear is provided. Moreover, the earring can give a gorgeous decorative feeling. The earring includes a supporting portion formed in a shape of a letter C to be put along a root of a human ear and a decorative body provided at an end of the supporting portion, wherein one end of the supporting portion is caught by an upper end of the ear, and a central part of the supporting portion abuts against a reverse side of the root of the ear. The decorative body is exchangeable.