406results about How to "Reduce infiltration" patented technology

The invention discloses a low-temperature sintering asymmetric porous silicon carbide ceramic membrane separation layer and a preparation method thereof, the preparation method comprises the following steps: a) preparation of a coating liquid: firstly dispersing a binder in a solution, adding silicon carbide particle powder, carrying out magnetic stirring dispersion for a period of time, then adding a dispersant, and stirring; then putting the stirred and mixed film coating liquid and the grinding balls into a ball milling tank for ball milling; and adjusting the pH value of the ball-milled silicon carbide coating liquid with ammonia water, and carrying out vacuum defoaming to finally obtain the high-stability and uniformly-dispersed silicon carbide coating liquid. Wherein the addition amount of the silicon carbide coarse particles is 0.5-50 wt% of the mass of silicon carbide; b) coating; c) drying; and d) sintering. The asymmetric porous silicon carbide ceramic membrane prepared by the method is low in sintering temperature, and the prepared separation layer membrane is controllable in pore size and uniform in pore size distribution; the method has excellent application prospects in the field of membrane separation.

The invention discloses an optical cable, which comprises an optical cable body, an optical cable fixing piece and a separator, one end of the optical cable body is coated with the optical cable fixing piece, and the middle of the optical cable body is coated with the separator. The optical cable body comprises a cable sheath, and optical fibers and reinforcing wires are arranged in the cable sheath. The optical cable fixing piece comprises a hoop, a first crimping ring and a second crimping ring, and the first crimping ring covers the hoop; and one end of the second crimping ring is crimped on the first crimping ring, the middle part is crimped on the reinforcing line on the surface of the hoop, and the other end is crimped on the cable skin. The hoop is provided with a first cavity, and an optical fiber and a seventh sealing piece are arranged in the first cavity. A reinforcing line is arranged between the first crimping ring and the hoop, and the reinforcing line does not exceed the first crimping ring. In the application, the first cavity of the hoop is filled with the seventh sealing member and the first crimping ring to crimp the reinforcing wire, the reinforcing wire does not exceed the first crimping ring, and the first crimping ring is matched with the seventh sealing member, so that the cooling liquid is prevented from permeating into the optical fiber in the optical cable.

The invention provides a high-water-resistance optical film and a polarizing plate comprising the same. The high-water-resistance optical film comprises a base film, a water-resistance layer and an adhesive layer, the structure of the high-water-resistance optical film comprises a water-resistance layer, a first adhesive layer, a base film and a second adhesive layer which are stacked in sequence, or the water-resistance layer, the base film and the second adhesive layer which are stacked in sequence, the surface of the waterproof layer is provided with nanometer protrusions and micropore structures which are uniformly and orderly arranged. The high-water-resistance optical film has excellent hydrophobicity, the water-resistance layer can efficiently absorb ultraviolet radiation, the problems of aging, yellowing, embrittlement and the like of the optical film caused by ultraviolet radiation are effectively prevented, the high-water-resistance optical film can be applied to a polarizing plate, and the service life of the polarizing plate is greatly prolonged.

The invention discloses a foundation pit supporting structure, and relates to the technical field of foundation pit supporting, and the foundation pit supporting structure comprises a supporting plate, a plurality of water absorption pieces and a plurality of positioning rods; a plurality of mounting grooves are formed in one side of the support plate, and the plurality of water absorption pieces are respectively arranged in the plurality of mounting grooves; a plurality of penetrating holes are formed in the supporting plate in a penetrating mode, a sharp thorn is arranged at one end of the positioning rod, and after the sharp thorn penetrates into soil at the bottom of a foundation pit, the part, located in the penetrating holes, of the positioning rod blocks openings in the bottoms of the penetrating holes; a plurality of water passing spaces, a plurality of first water seepage holes and a plurality of second water seepage holes are further formed in the supporting plate; the water passing space is communicated with the mounting groove through the plurality of first water seepage holes, and the water passing space is communicated with the through hole through the plurality of second water seepage holes. The supporting effect can be effectively achieved on the surrounding foundation pit with the high soil humidity, and meanwhile the probability of water permeation can be effectively reduced.

The utility model discloses an optical module and an optical cable. The optical cable is provided with an optical cable fixing piece and an isolation piece. The optical cable fixing member comprises a clamp and a first crimping ring. The clamp comprises a limiting projection. The first crimping ring is crimped on the hoop, and a reinforcing line is arranged between the first crimping ring and the hoop. The area between the limiting protrusion and the first crimping ring is a storage groove, a second sealing piece and a reinforcing line extending out of the first crimping ring are arranged in the storage groove, and the reinforcing line is arranged in the second sealing piece. The isolation piece comprises an isolation sleeve, a first protection sleeve and a second protection sleeve, the isolation sleeve covers the optical cable body, the first protection sleeve covers the isolation sleeve, and the second protection sleeve covers the first protection sleeve and the optical cable body located outside the first protection sleeve. According to the optical cable, the second sealing element and the reinforcing wire are arranged in the storage groove, and the reinforcing wire is arranged in the second sealing element, so that the situation that cooling liquid permeates into the optical cable body outside the optical module from the outside of the optical module is reduced; the second protective sleeve protects the optical cable body.

The invention discloses an antioxidant carbon aerogel material and a preparation method thereof. The method comprises the following steps: sequentially adding a solvent, a boron-containing modifier and a silicon-containing modifier into phenolic resin for esterification reaction; sequentially curing, drying and carbonizing to obtain boron-silicon modified carbon aerogel; depositing a SiC inner coating on the boron-silicon modified carbon aerogel under the assistance of supercritical CO2; a Zr-Si ceramic oxygen barrier layer and a SiO2 sealing and filling layer are sequentially prepared through a sol-gel method, and the carbon aerogel material with the SiC-Zr / Si-SiO2 composite coating is prepared. The invention also provides the aerogel material prepared by the method, the oxidation resistance of the aerogel material is obviously improved, and the aerogel material can be used for preparing a thermal insulation material applied to the field of high-temperature thermal protection.

The invention discloses a drug-loaded nanogel modified bioprosthetic valve as well as a preparation method and application thereof, and belongs to the technical field of preparation of medical materials and medical instruments. The preparation method comprises the following steps: firstly, synthesizing an active oxygen response monomer by taking thioketal-containing methacrylate and methylprednisone hemisuccinate as raw materials, then synthesizing active oxygen response type drug-loaded nanogel, and then introducing the active oxygen response type drug-loaded nanogel to the surface of the bioprosthetic valve through chemical bonding; in a pathological environment with relatively high active oxygen concentration, a thioketal group in the monomer is decomposed, and methylprednisone hemisuccinate is released at a fixed point, so that inflammatory cell infiltration is reduced, and the anti-inflammatory performance of the bioprosthetic valve is improved; in addition, the nanogel contains a large number of hydrophilic groups, a hydration layer is formed on the surface of the bioprosthetic valve, and the risk of thrombus and blood coagulation can be effectively reduced; the prepared bioprosthetic valve has excellent anti-inflammatory, anti-coagulation and anti-calcification capabilities and stability.

The invention relates to the technical field of toilet waterproofing, and provides a toilet waterproof structure and a construction method thereof.The toilet waterproof structure is arranged at the junction of a dry area finished surface and a wet area finished surface and sequentially comprises a threshold stone, a bonding layer arranged on the lower surface of the threshold stone and a waterproof layer arranged below the bonding layer from top to bottom; the upper surface of the threshold stone is flush with the upper surface of the dry area finished surface, the upper surface of the threshold stone is higher than the upper surface of the wet area finished surface, and the waterproof layer is laid on the upper surface of the structure base layer; the two sides of the waterproof layer extend to the positions below the dry area finished face and the wet area finished face respectively, and the waterproof layer comprises a first area arranged below the wet area finished face, a second area arranged at the junction of the threshold stone and the wet area finished face, a third area arranged below the threshold stone and a fourth area arranged below the dry area finished face. The waterproof structure has the beneficial effect that the waterproof effect of the doorsill of the toilet is improved.

The invention discloses a leuconostoc mesenteroides substrain, the preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) No.30904, the preservation date is June 7, 2024, the preservation classification is named as leuconostoc mesenteroides, and the preservation unit is the General Microbiological Culture Collection Center of the China Committee for Culture Collection of Microorganisms. The strain provided by the invention is harmless to animals, and has the remarkable effects of relieving lung tissue inflammatory infiltration caused by bronchial asthma, reducing release of serum IgE and Th2 type cell factors, inhibiting excessive lung macrophage replacement activation and improving allergic airway inflammation.

The utility model discloses a PLC automation control cabinet with a flat cable positioning structure, the PLC automation control cabinet comprises a cabinet body, the outer surface of the lower end of the cabinet body is fixedly connected with a pedestal body, the interior of the cabinet body is fixedly connected with an internal element, the interior of the pedestal body is provided with a pedestal groove, a rotating disc is nested and connected on the pedestal body, and the rotating disc is fixedly connected with the pedestal groove. The lower end of the rotating disc is fixedly connected with a first threaded rod, a stabilizing mechanism is arranged between the first threaded rod and the base groove, the second threaded rod is connected to the cabinet body in a nested mode, the outer end of the second threaded rod is fixedly connected with a handle, and the second threaded rod is in threaded connection with a moving plate. A user can enable a flat cable to penetrate through the interior of an arc-shaped plate, at the moment, under the driving of the elastic acting force of a reset spring, a limiting plate drives a clamping plate to move through a driving rod till the clamping plate makes contact with the flat cable, the flat cable is positioned and clamped, and the possibility of winding of the flat cable is reduced to a certain degree.

The invention belongs to the technical field of ceramic materials, and particularly discloses whisker toughened zirconium oxide-aluminum oxide composite ceramic and an additive manufacturing method thereof, the composite ceramic comprises the following components by mass: 94 parts of zirconium oxide toughened aluminum oxide ceramic and 5 parts of silicon carbide whisker; the zirconium oxide toughened aluminum oxide ceramic is prepared from the following components in parts by mass: 76 parts of aluminum oxide and 24 parts of zirconium oxide, and 3mol% of yttrium oxide is added into the zirconium oxide. According to the whisker toughened zirconium oxide-aluminum oxide composite ceramic and the additive manufacturing method thereof, the preparation method has unique design of components and process, and the preparation of a high-density and high-performance ceramic-based composite material part based on a fused deposition modeling technology is successfully realized. Further, the prepared silicon carbide whisker toughened zirconium oxide-aluminum oxide-based composite ceramic has relatively high density and excellent obdurability.

The invention discloses application of cimiprevir in preparation of a bacteriostatic agent and a medicine for preventing and treating periodontitis, and relates to the technical field of disease treatment by using cimiprevir. Studies find that cimiprevir can be combined with EF-Tu protein to inhibit adhesion of the EF-Tu protein to an interface, further inhibit adhesion of bacteria (especially oral streptococcus) to an oral interface and formation of a plaque biofilm, regulate proliferation and growth of the bacteria and play an effective bacteriostatic role, and cimiprevir can be used for preparing a bacteriostatic agent or a preparation for preventing and treating periodontitis; the composition can effectively reduce periodontal tissue damage, reduce alveolar bone absorption and reduce osteoclast infiltration, and is used for preparing a preparation for protecting periodontal tissue or alveolar bone.

The invention belongs to the technical field of high polymer material composite tarpaulin, and particularly relates to tear-resistant PVC (polyvinyl chloride) composite vehicle tarpaulin, equipment, a preparation method and application. The tarpaulin for the vehicle is composed of base cloth and PVC films attached to the two sides of the base cloth through PVC slurry. Wherein the PVC slurry comprises the following materials: 100 parts of PVC paste resin, 90-120 parts of a plasticizer, 4-8 parts of an adhesive, 11-12 parts of a viscosity reducer and 25-35 parts of PVC calcium powder; the thickness of the PVC slurry permeating into the base cloth is less than or equal to 1 / 3 of the thickness of the base cloth. Vehicle tarpaulin manufacturing equipment is improved, the bottom film pressing wheel and the surface film pressing wheel are additionally arranged to improve attachment of a PVC film and a large cylinder, an original padding process is changed into a transfer sizing method by means of the modified transfer sizing wheel set, the sizing gram weight and screen cloth permeation can be reduced, and the production efficiency is improved. The tarpaulin tearing performance is improved; and the tarpaulin has good stripping resistance and the like.

The invention relates to the technical field of railroad bed structures, and discloses a deep season frozen soil area existing railroad bed heat preservation, water insulation and frost heaving prevention structure and a construction method of the deep season frozen soil area existing railroad bed heat preservation, water insulation and frost heaving prevention structure. The invention relates to a heat-insulating waterproof frost heaving-preventing structure for an existing railroad bed in a deep seasonal frozen soil region. The overall cross section of the existing railroad bed is of an axial symmetry structure along the center line of the railroad bed; the existing railway subgrade foundation bed is sequentially provided with a first gravel cushion layer, a waterproof geotechnical cloth layer, a second gravel cushion layer, a geogrid layer and a closed railway ballast layer from bottom to top. Polyurethane heat preservation layers are arranged on side slopes on the two sides of the existing railroad bed. A polyurethane heat preservation layer and a waterproof geotechnical cloth layer are sequentially arranged on the road shoulders on the two sides of the existing railroad bed from bottom to top. A drainage channel is arranged at the slope toe of the existing railroad bed; a polyurethane heat preservation layer is arranged on the connecting section of the slope toe of the existing railroad bed and the drainage channel. The thermal-insulation waterproof frost heaving prevention structure for the existing railroad bed in the deep seasonal frozen soil region can be suitable for treatment and maintenance of frost heaving disasters of the existing railroad bed in the deep seasonal frozen soil region, and has a good engineering application prospect.

The utility model relates to the technical field of roads and bridges, in particular to a road and bridge panel joint reinforcing device which comprises a first panel, and a second panel is arranged on one side of the first panel. One side of the first panel and the interior of the second panel are jointly provided with a connecting assembly; the bottom ends of the first panel and the second panel are jointly provided with a reinforcing assembly. Through cooperative use of the square columns, the connecting blocks, the special-shaped blocks, the round rods and the circular truncated cones, the purpose of prolonging the service life of the panels can be achieved, dependence of a single bolt is reduced, a more stable and compact structure can be provided, and therefore the overall bearing capacity and stability are enhanced, displacement and looseness between the panels are reduced, and the service life of the panels is prolonged. The maintenance and repair requirements are reduced, the maintenance cost is reduced, the maintenance period is shortened, and the aging and abrasion of the pavement are effectively slowed down.

The invention discloses a fibroblast exosome for repairing scars and a preparation method and application thereof, and relates to the technical field of biology, and the preparation method comprises the following steps: S1, taking fibroblasts, and carrying out adaptive culture on the fibroblasts in a complete culture medium for 24-30 hours; s2, after the adaptive culture is completed, replacing a new culture medium, culturing in a complete culture medium containing 10% of fetal calf serum until the fusion degree is 80%, carrying out digestion treatment by adopting 0.25% of pancreatin, centrifuging, collecting supernate, and carrying out ultracentrifugation extraction on the supernate to obtain a primary product of the fibroblast exosome; s3, carrying out transfection treatment on the primary product of the fibroblast exosome to obtain the fibroblast exosome for repairing scars; the prepared fiber-forming exosome can also influence the movement of epidermal and dermal cells by regulating the expression of related factors in a TGF-beta / Smad signal channel, and the regulating effect is mainly to promote scar-free healing of the skin, so that the generation of scars is reduced from the source.

The invention discloses a natto peptide sea cucumber polysaccharide liposome for synergistically improving cardiovascular health and a preparation method and application thereof, belongs to the field of active peptide delivery systems, and aims to solve the stability problem of natto oligopeptide in gastrointestinal digestive tracts. The phytosterol and the vitamin E are filled between phospholipid double layers of the liposome to support a gap between the phospholipid double layers, and the ratio of the phytosterol to the vitamin E is (1-3): 1, so that the natto oligopeptide liposome has the effects that the storage of the natto oligopeptide and the stability of the natto oligopeptide in gastrointestinal and digestive tracts can be improved, the bioavailability of the natto oligopeptide liposome is improved, and the bioavailability of the natto oligopeptide liposome is improved. The traditional Chinese medicine composition has synergistic effects in the aspects of anticoagulation, thrombolysis and blood fat reduction, and has a good cardiovascular protection effect.

The invention provides an anti-inflammatory substance and application thereof, and relates to the technical field of molecular biology. The docosahexaenoic acid can be used for effectively inhibiting expression of mRNA (messenger ribonucleic acid), protein and supernatant of IL-1beta (interleukin-1beta) of RAW264.7 cells induced by LPS (lipopolysaccharide); in addition, the docosahexaenoic acid can play a role in relieving inflammation in a transdermal administration mode, and the technical effect of inhibiting or treating inflammation in a non-invasive and safe mode is achieved.

The invention relates to a water-soluble antioxidant nanosheet as well as a preparation method and application thereof in acute liver injury, and relates to the technical field of nano-drugs. The water-soluble antioxidant nanosheet disclosed by the invention is obtained by self-assembling two-dimensional transition metal disulfide and protein, and has proper size, good life compatibility and superstrong antioxidant activity. The water-soluble antioxidant nanosheet disclosed by the invention can be used for effectively treating acute liver injury induced by acetaminophen by inhibiting oxidative stress; damaged liver tissues can be effectively targeted, and a treatment effect is achieved; mitochondrial ROS level can be reduced, mitochondrial membrane potential can be recovered, and mitochondrial damage can be reduced; the level of inflammatory factors of the liver in the acute liver injury process can be remarkably reduced, infiltration of macrophages is reduced, and excessive inflammatory response of the liver is relieved. The preparation method of the water-soluble antioxidant nanosheet is a simple and green synthesis method, and raw materials are low in price and easy to obtain.

The utility model discloses a waterproof and drainage structure for an open cut tunnel, and relates to the technical field of tunnel construction. A tunnel open cut tunnel waterproof and drainage structure comprises a ground line, a clay waterproof layer fixed to the lower end of the ground line, a foundation fixed to the lower end of the ground line, a tunnel wall fixed to the foundation, an inverted arch fixed to the lower end of the tunnel wall, a center pipe fixed to the lower end of the inverted arch, a backfill layer arranged between the tunnel wall and the clay waterproof layer, and side water grooves formed in the two sides of the tunnel wall. The side water tank is fixedly connected with the foundation, a protection plate is arranged between the backfill layer and the tunnel wall, an arc-shaped drainage pipe is arranged between the tunnel wall and the protection plate and communicates with the side water tank, and a supporting mechanism is arranged on the protection plate. When the waterproof and drainage mechanism is used, the inverted arch improves the stability of the tunnel, the arc-shaped drainage pipe is supported and protected through the supporting mechanism, deformation and damage of the arc-shaped drainage pipe are reduced, and the influence on the tunnel is reduced.

The invention provides toughened anti-cracking and anti-corrosion solid waste concrete and a preparation method thereof. Mixing the cement, the fly ash, the slag and the natural aggregate; sequentially adding water, a weakly alkaline regulator and an additive solution containing a polycarboxylic acid water reducer to obtain concrete slurry; and curing to obtain the product. According to the invention, fly ash, slag solid waste and natural aggregate are used as aggregate, a water reducer is added to reduce the water consumption of concrete and improve the fluidity of concrete, and specially-made weakly-alkaline conditioning agent particles are introduced, so that the self-water-absorption-water-release behavior and bridging effect of the particles are utilized to improve the concrete fluidity. The early-stage and later-stage continuous hydration ability of a rubber material in the concrete is enhanced, the self-shrinkage and drying shrinkage resisting effects are achieved, the compactness and corrosion resistance of the concrete are improved, and then the anti-cracking ability of the all-solid waste concrete is improved. The surface of an obtained test piece is free of cracks, the 28d compressive strength reaches 46.6 MPa, the 28d breaking strength reaches 8.5 MPa, the self-shrinkage rate is 0.035%, and the drying shrinkage rate is 0.01%.

The invention discloses a connector and a processing method thereof. The connector comprises a terminal module and an insulating shell formed on the outer side of the terminal module in an injection molding mode. The terminal module comprises a first terminal and an insulating body which is formed on the outer side of the first terminal through injection molding; one side surface of the insulating body is provided with at least one forming positioning groove; wherein one side of the insulating shell is provided with a butt joint cavity, and the other side is provided with an accommodating cavity; one end of the first terminal is located in the butt joint cavity, and the other end of the first terminal penetrates out of the accommodating cavity; the forming positioning groove is located in the butt joint cavity and communicates with the butt joint cavity. One side surface, deviating from the molding positioning groove, of the insulating body is at least partially exposed in the accommodating cavity to form an exposed area. The insulating body is fixed in an injection mold by arranging the molding positioning groove and the exposed area, and components for clamping the insulating body can be respectively pulled out from the butt joint cavity and the accommodating cavity, so that no open hole is left on the outer surface of the insulating shell, the wrapping integrity of the terminal module is improved, and the waterproof performance and the structural strength of the connector are improved.

The invention discloses a fluoride corrosion resistant photovoltaic panel self-cleaning coating which is prepared by reaction of the following raw materials: a component A, a component B and 10-20 parts of nano nickel oxide, the component A is organic silicon modified fluorocarbon resin, the component B is an organic silicon modified fluorocarbon resin curing agent, and the nano nickel oxide is an organic silicon modified fluorocarbon resin curing agent. The component B is prepared from the following components in parts by weight: 100 to 120 parts of hexamethylene diisocyanate tripolymer, 35 to 45 parts of monohydroxyl terminated polydimethylsiloxane and 30 to 35 parts of octafluoro-1, 6-hexanediol; all the parts represent parts by weight. The fluoride corrosion-resistant photovoltaic panel self-cleaning coating disclosed by the invention can effectively resist the corrosion effect of fluoride, and also needs to have an excellent self-cleaning function.

The invention discloses an application of a meroterpenoid compound I in preparation of an anti-heart failure medicine. The meroterpenoid I separated and purified from marine fungi Aspergillus terreus GZU-311 is used for treating a mouse heart failure model induced by adriamycin or coronary artery left anterior descending branch ligation, and it is found that the meroterpenoid I can improve the heart function of a mouse, reduce myocardial cell damage, inhibit myocardial connective tissue thickening and improve myocardial cell arrangement disorder, and the meroterpenoid I can be used for treating the heart failure of the mouse induced by adriamycin or coronary artery left anterior descending branch ligation, so that the meroterpenoid I can be used for treating the heart failure of the mouse induced by adriamycin or coronary artery left anterior descending branch ligation. Inflammatory cell infiltration is reduced, and the effect of resisting heart failure is achieved. Therefore, the invention provides the application of the meroterpenoid I in preparing the heart failure resisting medicine. According to the invention, medicine source molecules for treating heart failure are enriched, and development and clinical treatment of anti-heart-failure medicines are facilitated.

The invention belongs to the technical field of secondary batteries, and particularly relates to a diaphragm as well as a preparation method and application thereof. According to the diaphragm provided by the invention, by selecting the wetting agent in the coating layer, limiting the dosage of the wetting agent and limiting the proportional relation between the particle size D of the PMMA particles and the thickness H of the coating base layer, the breakdown strength of the diaphragm is improved, and meanwhile, the influence of the wetting agent on the insulating property of the diaphragm is avoided. In addition, compared with a conventional layered multi-time coating diaphragm with a base film, a heat-resistant coating and a bonding coating, through the mixed coating mode of inorganic particles and large-particle PMMA, the simplification of the coating layer is realized, the bonding and heat-resistant requirements on the coating layer are met, the production cost of the diaphragm is reduced, and the requirement on production equipment is not higher.

The invention discloses a super-hydrophobic PVC material and a preparation method, the super-hydrophobic PVC material comprises the following raw materials by weight: 100 parts of PVC resin, 1-3 parts of TPE, 1.5-2 parts of titanium dioxide, 1-3 parts of CR, and 5-12 parts of a performance additive, the particle size of the performance additive is 300-400 nm, the performance additive takes inorganic hard particles as a core, the exterior of the performance additive comprises a continuous anti-sticking layer and an uncovered anti-sticking bonding surface, and the surface of the performance additive is coated with an anti-sticking layer. According to the PVC material disclosed by the invention, hydrophobic modification can be performed on the surface of the PVC material and a large number of hydrophobic nano salient points are formed under the conditions that the addition amount of fluorine-containing organic silicon resin is small and the strength performance of the PVC material is kept to reach the standard, so that the hydrophobicity of the surface of the PVC material is remarkably improved; infiltration of water on the surface of the PVC material is reduced, hair can be washed away conveniently, and accumulation of hair on the inner wall of a PVC pipe made of the PVC material is reduced.

The invention belongs to the technical field of medicines, and particularly discloses application of binding molecules of actin binding protein LASP1 in prevention and treatment of acute respiratory distress syndrome (ARDS). According to the invention, the LASP1-loaded nanoparticles are constructed, so that the problems that the drug is difficult to penetrate and easy to remove and degrade and the ARDS is difficult to treat are solved. According to the invention, through intranasal instillation of the HA-DA / BP / LASP1 nanoparticles, the level of inflammatory factors can be reduced, the alveolar epithelial barrier structure and function can be repaired, and the death rate of ARDS model mice can be reduced.

The invention belongs to the technical field of application of traditional Chinese medicines, and specifically relates to an application of an Amomum villosum extract in preparing a UA-lowering and anti-gouty arthritis drug. The Amomum villosum extract is extracted to obtain the Amomum villosum extract. A hyperuricemia mouse model and a gouty arthritis mouse model are established, and the results show that the Amomum villosum ethanol extract reduces the UA level by synergistically reducing excessive UA generation and promoting UA excretion, and comprehensively exerts an anti-gout effect by inhibiting the release of inflammatory factors such as IL-6, TNF-α and IL-1β, and has the characteristics of better drug efficacy and better drug safety. Therefore, the Amomum villosum ethanol extract can be applied to drugs and health foods for gout patients, and has better development and utilization value as well as huge social and economic benefits.

The utility model relates to the technical field of control valves, in particular to an ultralow-temperature gate valve which comprises a valve body, a gate plate arranged on the valve body in a sliding mode, a valve seat used for being matched with the gate plate to seal the gate valve, a valve rod used for driving the gate plate to move, a hand wheel used for driving the valve rod to rotate and a heat preservation mechanism used for conducting heat preservation on the gate valve. The valve body is wrapped with the heat preservation cover and used for sealing and heat preservation of the valve body; the isolation assembly is arranged on the valve body and located above the heat preservation layer, and the isolation assembly is used for isolating the non-heat-preservation part from the heat preservation part and isolating condensate water generated above the isolation assembly. The hand wheel drives the valve rod to rotate and drives the gate plate to slide, so that opening or closing of the valve body is achieved, the valve body is wrapped and subjected to heat preservation through the heat preservation layer, accumulated water above the isolation assembly is blocked through the isolation assembly and drained in time, the probability that condensate water permeates into the heat preservation layer is reduced, and the service life of the valve body is prolonged. Therefore, the heat preservation effect of the gate valve on internal media is improved.

This application provides a display panel, its manufacturing method, and an electronic device. The manufacturing method includes sequentially fabricating an array of anode layers on one side of a substrate; fabricating a pixel definition layer covering the substrate and the peripheral areas of each anode layer, such that the pixel openings of the pixel definition layer expose the central area of ​​the anode layer; and forming a polymer film on the surface of the pixel definition layer away from the anode layer under first design conditions, where the first design conditions include oxygen. In this application embodiment, the formation of the polymer film requires oxygen consumption, which helps reduce oxygen infiltration, thereby reducing the oxygen concentration on the anode surface, thus reducing the surface voltage of the display panel and improving its lifespan.