130 results about "Skin patch" patented technology

Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.

A system, method and apparatus for real time measurement and monitoring of various personal health parameters including controlled delivery of drugs/medications by intelligent pump appliances, intelligent inhalation appliances and intelligent skin patch appliances used in a standalone manner or in a wired or wireless networked configuration, in conjunction with various peripheral devices, other intelligent appliances, servers, RF ID Tags and stationary/mobile devices. The intelligent appliances relate to the measurement, monitoring and delivery of insulin/other drugs for the treatment of diabetes and other diseases. The method also additionally includes the application of intelligent appliances for pain management including visualization of organs and body locations exhibiting pain.

Microneedle arrays are provided for use on a contoured or flexible tissue surface. In one embodiment, the microneedle array includes a plurality of microneedles, each having a base portion, a tip end portion distal to the base portion, and body portion therebetween; and a flexible substrate which comprises a plurality of apertures, each of which are defined by (i) a plurality of substrate elements which are integral with the base portions of the microneedles, and (ii) at least one spring element connecting at least two of the substrate elements. The spring element may include a curved element, such as a C-shaped, U-shaped, or S-shaped element. Apertures may be defined, for example, by two substrate elements, which connected to three or four spring elements. A skin patch is provided for therapeutic or diagnostic applications, which includes the microneedle array and an adhesive material.

A catheter and patch electrode system is provided for use with an apparatus, such as an ablation generator, having a 4-wire interface for improved impedance measurement. The 4-wire interface includes a pair of source connectors across which an excitation signal is produced and a pair of sense connector wires across which the impedance is measured. The RF ablation generator may also produce an ablation signal across a source wire and an indifferent return patch electrode. The system further includes a cable that connects the generator to a catheter. The catheter includes a shaft having a proximal end and a distal end, with an ablation tip electrode disposed at the distal end. A source lead is electrically coupled to the tip electrode and extends through the shaft to the proximal end where it is terminated. An optional sense lead is also electrically coupled to the tip electrode and extends through the shaft to the proximal end. The system further includes a source return (e.g., skin patch) and a sense return (e.g., skin patch), either or none of which may be combined with the indifferent return, and if used may be placed on opposite sides of the patient for improved performance. The impedance sensor circuit produces an excitation signal across the source connectors, which is then carried to the catheter by the cable, then to the tip electrode, travels through the complex load (tissue volume), and returns to the generator via a patch electrode. The impedance is measured by observing the voltage drop across the sense connectors caused by the excitation signal.

Embodiments of the invention provide systems and methods for remote sensing and/or monitoring utilizing a sensing device, such as may be implemented in a patch that can be placed on or affixed to a subject, where the sensing device includes multiple sensors. For example, one embodiment of the present invention includes a wireless human temperature skin patch providing accurate measurement of human temperature from a sensing device applied to the skin and even in the presence of differing ambient temperature. In such an embodiment, the patch can include, for example, a flexible, breathable bandage or adhesive strip or pad to affix the sensing device to a patient. The sensing device can include multiple sensors such as two or more temperature sensors that can be used to accurately determine the patient's core body temperature from the measured temperature at the skin.

A system, method and apparatus for real time measurement and monitoring of various personal health parameters including controlled delivery of drugs/medications by intelligent pump appliances, intelligent inhalation appliances and intelligent skin patch appliances used in a standalone manner or in a wired or wireless networked configuration, in conjunction with various peripheral devices, other intelligent appliances, servers, RF ID Tags and stationary/mobile devices. The intelligent appliances relate to the measurement, monitoring and delivery of insulin/other drugs for the treatment of diabetes and other diseases. The method also additionally includes the application of intelligent appliances for pain management including visualization of organs and body locations exhibiting pain.

This invention relates to a novel transdermal drug delivery system whereby Huperzine A ("Hup A"), a naturally occurred Acetylcholine esterase inhibitor traditionally used to alleviate memory problem, is formulated for transdermal administration suitable for the treatment of Alzheimer's Disease ("AD") to increase the efficacy and convenience for outpatient care of AD patients. A controlled-release skin patch designed for once-a-week application of Hup A is provided for easy AD medication according to the invention.

Receiver apparatus for use with an analyte sensor, and methods of operation and manufacturing. In one embodiment, the analyte sensor is an implanted/implantable blood glucose sensor, including oxygen-based detector elements. The receiver apparatus is a wireless-enabled small form-factor device with limited functionality that can be easily worn or kept with the user on a continual basis, thereby obviating the need for a more fully featured receiver or smartphone for extended periods of time (e.g., one week). The exemplary oxygen based analyte sensor, with high degree of stability over time, enables the user to divorce themselves from the more fully functioned receiver or smartphone, since no external calibration of the sensor is required during the extended period. In one variant, the device is a lightweight wristband. Other variants include e.g., pendants, finger-worn rings, arm or head bands, skin patches, and even dental, subcutaneous, or prosthetic implants.

A skin-patch type large volume medicament injection device (1) comprising an adhesive surface (21/23) for attachment to the skin and a plurality of contact sensors (24) configured to output a signal representing a degree of detachment of the device from the injection site, and an alarm and control function which outputs an alert to the user based on the signal received from the sensors and stops the injection in case the degree of detachment is too large to guarantee further save injection.

To have acceptable moisture permeability and enable prevention of deformation due to swelling, the film base material for an adhesive skin patch includes an ether-based urethane resin obtained from at least one member selected from the group consisting of polyoxytetramethylene glycol, butanediol, polyethylene glycol, and polypropylene glycol as a diol component, and methylene diphenyl-diisocyanate as an isocyanate component. The film base material for an adhesive skin patch has a moisture permeability of preferably 800 to 4,000 g/m²·24 hrs. The adhesive skin patch can be produced by forming a pressure-sensitive adhesive layer on one side of the film base material for an adhesive skin patch.

Copper ion treatments for dermatological areas of the body include solutions, creams, lotions, gels, foams, wound dressings, skin patches and suture material, each containing copper ions that bring about therapeutic effects when the copper ion treatments are applied to dermatological tissue. Methods of treating dermatological areas of the body include treatments for use on the skin and nails to treat conditions including disease, infection, inflammation, damaged or injured tissue, tissue needing to be sutured, rashes and other undesirable dermatological conditions.

Provided are a skin patch sheet including a carrier sheet, an adhesive patch and a release liner laminated in this order, in which (a) the adhesive patch includes two layers, namely, a backing and an adhesive layer having the same shape; (b) the carrier sheet is adjacent to the backing of the adhesive patch; (c) the skin patch sheet includes a grip section and a body section; (d) in the body section or the body section and grip section, the area of the release liner is larger than the area of the adhesive patch; (e) the boundary between the grip section and the body section is a slit line formed by a slit; and (f) the slit extends from the side of the release liner, penetrating into the adhesive patch, up to a depth in the range of greater than or equal to 20% and less than 50% of the thickness on the adhesive patch side of the carrier sheet; a skin patch sheet in which plural sheets of adhesive patches on which carrier sheets are laminated are formed in a parallel arrangement on a release liner; use of the skin patch sheet by attaching the skin patch sheet to the skin surface in order to prevent direct scratching of an affected site of the skin, or by attaching the skin patch sheet to the face for a lift-up effect; and a method for attaching the skin patch sheet.

Provided herein are topical formulations containing copper ions and methods of treating inflammatory, microbial, and arthritic conditions in various areas of the body using such formulations. Methods of treating osteoarthritis using topical copper ion treatments are provided. Methods of treating and preventing microbial infections using copper ion treatments are further provided, including methods of preventing biofilm. A topical treatment in its basic form comprises a biocompatible copper ion solution or suspension obtained by leaching of the copper ions from copper metal. The copper ion solution or suspension is combined with various carriers to form the copper ion treatment including creams, gels, lotions, foams, pastes, tampons, solutions, suppositories, body wipes, wound dressings, skin patches, and suture material. Methods of making the copper ion solution or suspension from solid copper metal in a biocompatible solution are also provided.

The present invention relates to the treatment of eczema. More specifically, the invention relates to a new method of treating eczema through the epicutaneous route. In particular, the method of the invention comprises applying to a non eczematous area of the skin of the subject a skin patch device, comprising a composition, under conditions allowing a contact between said composition and the skin. The present invention also relates to the skin patch device.