The invention discloses a high precision portable electrochemical detection terminal. In the prior art, the conventional electrochemical detector has the disadvantages of complicated structure, bad interference resistant performance, bade stability, and low detection precision, and the provided detection terminal solves the problems mentioned above. The detection terminal is characterized by comprising a forward voltage follower circuit, a RE electrode and CE electrode based on the forward voltage follower circuit, a current/voltage conversion circuit, a WE electrode based on the current/voltage conversion circuit, and a three-circle opposite vertex intersected negative feedback amplifier, which is connected to the current/voltage conversion circuit. The provided detection terminal has the advantages of simple circuit, good circuit stability, strong interference resistant property, low energy consumption, and high testing precision, and thus is suitable for promotion and application.