9 results about "Ethyl gallate" patented technology

This invention discloses a method for preparing alkyl gallate without a dehydrating agent, belonging to the field of chemical reaction auxiliary technology. By optimizing the raw material ratio of the reaction system, precisely controlling the reaction environment parameters and the condensate separation rate, this invention utilizes the azeotropic properties of alcohol and water to achieve efficient separation of the water generated in the reaction. It can promote the forward esterification reaction without adding any dehydrating agent, achieving the same or even better water separation and reaction promotion effects without the need for a dehydrating agent. This invention eliminates the need for a dehydrating agent, and the synthesized methyl gallate, ethyl gallate, propyl gallate, octyl gallate, and lauryl gallate can reach a maximum content of 99.2%, with a stable product yield of 50-57g. This effectively reduces production costs, avoids the pollution problems caused by dehydrating agents, simplifies the production process, and possesses both green environmental protection and promising prospects for industrial-scale application.

The invention relates to the technical field of biological medicine, in particular to a composition for blocking formation of phage treatment tolerance and application of the composition. The composition comprises a folium ilicis purpurea ethyl acetate extraction active component and a clostridium perfringens specific bacteriophage, the folium ilicis purpurea ethyl acetate extraction active component is prepared from the following components in percentage by mass: 8 to 15 percent of protocatechuic acid and 5 to 10 percent of ethyl gallate, and the mass ratio of the protocatechuic acid to the ethyl gallate is (1.5 to 1) to (2.5 to 1); the clostridium perfringens specific bacteriophage is a virulent bacteriophage capable of specifically cracking a clostridium perfringens NetB toxin positive strain. According to the invention, the shallow thought that the existing compounding technology only pursues synergistic sterilization is subverted, and a deep synergistic mode of bacteriophage splitting attack and folium ilicis purpurea component disintegration bacterial defense program is proposed and verified for the first time. And the formation of tolerance is fundamentally blocked, so that a more thorough and more lasting treatment effect is realized, and the comprehensive production performance of animals is accidentally and greatly improved on the basis of the treatment effect.

This application relates to the field of food processing technology, specifically to a zein-based oleogloss with a polyphenol self-assembled coating, its preparation method, and its application. The preparation method includes the following steps: dissolving zein in an ethanol-water solution, adjusting the pH to 10-12 for pretreatment, and removing the ethanol by heating and stirring at 30-50°C to obtain a zein dispersion; first adding epigallocatechin gallate, then adding Ca... 2+ A composite particle dispersion was prepared; the composite particle dispersion was mixed with liquid oil to prepare a Pickering emulsion, which was then dried in the dark with cold air to obtain a solid fat; the solid fat was dispersed to prepare a zein-based oleogel based on a polyphenol self-assembled coating; zein, Ca... 2+ The ratio of epigallocatechin gallate to ethyl gallate is 2g:0.05mmol:0.05mmol. The preparation method described in this application is simple and environmentally friendly, suitable for mass production. The prepared zein-based oleogel exhibits good stability, strength, and resistance to deformation, and is not easily oxidized.

The invention belongs to the technical field of medicine and pharmacy, and particularly relates to application of an AP1B1 allosteric activator of ethyl gallate. In the invention, AP1B1 is a beta 1 subunit (AP1B1) of a linking factor associated protein complex 1 (AP-1), and is an essential component for assembling a functional AP-1B complex. The ethyl gallate is used as an allosteric activator of AP1B1 and is specifically combined with an allosteric pocket of the AP1B1 to induce the AP1B1 to generate conformational change, so that the vesicle transportation function of an AP1B complex is activated, and the substrate-side membrane protein sorting capacity is recovered. A target dependence experiment verifies that the effect of ethyl gallate on promoting tight junction protein ZO-1 expression and membrane localization in AP1B1 knocked-down Caco-2 cells is remarkably weakened, and it is prompted that the intestinal barrier protection function of ethyl gallate depends on AP1B1. The invention provides a new strategy for developing medicines for treating intestinal barrier injury related diseases.

The invention discloses a preparation method of a traditional Chinese medicine composition for treating skin tinea, allergic dermatitis and acne, and relates to the field of pharmaceutical preparations, the extraction rate of gallic acid and ethyl gallate contained in total tannin in fructus chebulae flesh, fructus terminaliae billericae flesh and fructus chebulae immaturus is improved through an enzymolysis method, and the transfer rate of effective components of quercetin is improved through a boiling granulation technology; therefore, the effect of treating psoriasis of the composition is improved. By adopting a boiling granulation technology, the technical problems of long preparation period and high cost in the prior art are solved. The release speed of aloe in intestinal tracts is controlled by adopting a slow release technology, and the upper and lower limit content range of barbaloin is controlled to reduce the occurrence rate of adverse reactions of the composition. Meanwhile, butyl hydroxy anisd (BHA), butylated hydroxytoluene (BHT) and a citric acid system are adopted, so that the problems of PEO skeleton degradation, out-of-control drug release behavior and insufficient main drug stability of the barbaloin-PEO sustained release preparation are solved.

The application belongs to the technical field of natural fruit active substance detection, and discloses a method for simultaneously detecting the contents of multiple active components in green fruits based on HPLC, wherein the active components include seven main active components in green fruits, i.e., pyrogallol, gallic acid, epicatechin, ethyl gallate, p-coumaric acid, epigallocatechin and ellagic acid. The detection method established by the application is good and the instrument is precise, and the method has the technical advantages of good selectivity, high sensitivity and accuracy and reliability for detecting the contents of the main active components in green fruits, thereby providing a new analysis method and reliable basis for quality analysis and quality control of green fruits.

This invention belongs to the field of tea production fermentation technology, specifically disclosing a *Fungi* strain for improving tea quality and its application, namely *Fungi* strain Fungi37, classified and named... Diaspora masirevicii The strain, with accession number CGMCC No. 42364, is a rare endophytic fungus found in tea plants and is the first reported strain in the field of tea. Experiments have shown that this strain can significantly enhance the brightness and vividness of tea infusion and play a certain regulatory role in the flavor presentation of tea. Metabolomics analysis shows that this bacterium can promote the large-scale conversion and synthesis of active ingredients such as methyl caffeate, methyl gallate, ethyl gallate, hesperidin, and isosulfanol during tea fermentation. Furthermore, in an exogenous sugar-added environment, it can promote the conversion and synthesis of beneficial components such as dihydromyricetin, yarrow aglycone, isochlorogenic acid A, plantainin, malic acid, sorbic acid, and gluconic acid.

The invention belongs to the technical field of tea production and fermentation, and particularly discloses a phlomis spp. Strain capable of improving tea quality and application of the phlomis spp. Strain, the classification name of the phlomis spp. Strain is Diaporthe masrevicii, and the preservation number of the phlomis spp. Strain is CGMCC No.42364. The strain is reported for the first time in the field of tea and belongs to a rare tea tree endophyte. Experiments prove that the strain can significantly improve the brightness and the brilliance degree of tea soup, and has a certain adjusting effect on the taste of the tea soup; metabonomics analysis shows that the strain can promote mass conversion and synthesis of functional components such as methyl caffeate, methyl gallate, ethyl gallate, hesperidin, isoschaftoside and the like in a tea soup fermentation process; the conversion and synthesis of beneficial components such as dihydromyricetin, leucocyanidin, isochlorogenic acid A, plantaginin, malic acid, sorbic acid and gluconic acid can be promoted in an exogenous sugar addition environment.

The invention relates to a traditional Chinese medicine composition, which is an active component extracted from cassia twig, poria cocos, moutan bark, peach kernel and white paeony root, and the active component comprises the following components in percentage by mass: more than 0.214% of gallic acid, more than 0.008% of 4-hydroxybenzoic acid, more than 0.083% of oxypaeoniflorin, more than 1.112% of paeoniflorin, more than 0.012% of sodium hyaluronate and more than 0.012% of sodium hyaluronate. The content of ethyl gallate is more than 0.010%, the content of 1, 2, 3, 4, 6-O-pentagalloylglucose is more than 0.155%, the content of benzoic acid is more than 0.041%, the content of cinnamic acid is more than 0.015%, the content of benzoylpaeoniflorin is more than 0.093%, the content of cinnamaldehyde is more than 0.037%, the content of paeonol is more than 0.622%, and the content of amygdalin is more than 1.001%. The content of large-class components, namely water-soluble polysaccharide, is 1.743% or above, the content of alkali-soluble polysaccharide is 29.671% or above, and the total content of monosaccharide and disaccharide is 9.231% or above.