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75 results about "Ciprofloxacin Hydrochloride" patented technology
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The hydrochloride salt form of ciprofloxacin, a fluoroquinolone related to nalidixic acid with antibacterial activity. Ciprofloxacin hydrochloride exerts its bactericidal effect by interfering with the bacterial DNA gyrase, thereby inhibiting the DNA synthesis and preventing bacterial cell growth.
Preparation method of magnetic chitosan composite microsphere adsorbent
InactiveCN103920472AEasy to makeImprove thermal stabilityOther chemical processesWater contaminantsPolymer scienceMicrosphere
The invention relates to a preparation method of a magnetic chitosan composite microsphere adsorbent, which belongs to the technical field of environmental material preparation. The preparation method comprises the following steps: firstly with FeCl3. 6H2O and FeCl2.4H2O as raw materials, preparing nano Fe3O4 by a coprecipitation process; and secondly, with glutaraldehyde as a crosslinking agent and Fe3O4, kaolin and chitosan as raw materials, synthesizing the novel magnetic chitosan composite microsphere adsorbent by an emulsification crosslinking process. The magnetic chitosan composite microsphere adsorbent is used for separating ciprofloxacin hydrochloride out of a water environment. The adsorption performance and the dynamic performance of the prepared adsorbent are researched in a static adsorption experiment. The results show that the novel magnetic chitosan composite microsphere adsorbent obtained by the method has a rapid adsorption dynamics characteristic, a high adsorption capacity and high magnetic-separation efficiency.
Owner:JIANGSU UNIV
Fertilizer and pesticide combination reagent for preventing and killing bacterial canker of kivifruit and preparation method of fertilizer and pesticide combination
ActiveCN104628481AHigh affinityHigh activityNitrogenous fertilisersFertilizer mixturesLiquid productFermentation
The invention discloses a fertilizer and pesticide combination reagent for preventing and killing bacterial canker of kiwifruit and a preparation method of the fertilizer and pesticide combination reagent. The fertilizer and pesticide combination reagent is prepared from the following raw materials in parts by weight: 200 parts of agricultural amino acid water soluble powder, 40-50 parts of anhydrous zinc chloride, 45-65 parts of anhydrous manganese chloride, 40-80 parts of a ciprofloxacin active compound or a ciprofloxacin active compound, 100-200 parts of a 14% methyl chloride isothiazolinone water agent, 100-150 parts of oxine-copper active compound, 0.1 part of forchlorfenuron, 0.1 part of a 5-nitroguaiacol sodium salt active compound, 0.5 part of an alpha-pimacol active compound, 350-450 parts of molasses microbial fermentation concentrate solution, 0.2-0.25 part of sodium polyacrylate powder, 50-60 parts of No.YD-7 liquid fertilizer synergia solution, 0.1-0.2 part of industrial alcohol and the balance of deionized water to supplement the raw materials to 1200-1250 parts. The fertilizer and pesticide combination reagent disclosed by the invention is a high-density liquid product with fertilizer and pesticide effects, has good affinity for both water and plants, mainly contact and kill plant bacteria, and can also kill pathogenic fungus. A layer of compact organic pesticide and fertilizer film is formed outside a tree body when the fertilizer and pesticide combination reagent is applied in large concentration, and a sustained release function is exerted.
Owner:贵州三福生物科技有限公司 +1
Preparation method of in-situ gel sustained-release preparation for treating Bovine mastitis
InactiveCN101664381AAdhesiveIncrease lethalityOrganic active ingredientsPharmaceutical delivery mechanismMass ratioMastitis
The invention relates to a preparation method of in-situ gel sustained-release preparation for treating Bovine mastitis, which is characterized in that: the preparation steps are as follows: weighingciprofloxacin hydrochloride and film formation high molecular material chitosan according to a weight ratio of 0.1-0.5:1; dissolving the mixture of the two in water to prepare an aqueous solution containing 1 percent of chitosan, spraying and drying the aqueous solution to prepare a chitosan microsphere containing ciprofloxacin hydrochloride; distributing the obtained microsphere containing drug into the mixture aqueous solution formed by poloxamer 188 and poloxamer 407 according to the mass ratio of 0.1-5:1, thus obtaining the temperature-sensitive in-situ gel sustained-release preparation for treating Bovine mastitis. The sustained-release microcapsule containing inflammation diminishing medicine is distributed in the solution of high polymer material capable of forming gel at the body temperature. The in-situ gel containing inflammation diminishing medicine can treat Bovine mastitis by perfusion in breast; and the preparation method is simple, the product is safe in use, and the curative effect is accurate.
Owner:TIANJIN SHENGJI GRP CO LTD
Exterior-applied medicine for treating dermatopathy
InactiveCN101129522ANot corrosiveSignificant effectHydroxy compound active ingredientsDermatological disorderDiseaseDexamethasone acetate
The invention discloses an externally-used medicament for treating skin diseases, which is prepared from Chinese honey locust, Clematis chinensis, hooked uncaria, arisaema tuber, cnidium fruit, boneol, camphor, menthol, dried alum, broom cypress fruit, cactus, sea tangle, vitamin C, ciprofloxacin hydrochloride, vitamins, griseofulvin, abomacetin enteric coated tablet, dexamethasone acetate tablet, compound sulfalene oxazole tablet, sesame oil, edible glycerol, seed powder of Gorgon euryale and 20 Degree light wine.
Owner:滕大浪
Chitose/polyglycol blending medicine film and its preparing method as well as purpose
InactiveCN101156958AImprove performanceEliminate weaknessesAbsorbent padsBandagesWound dressingMass ratio
The invention discloses a chitosan / polyethylene glycol blend drug-loaded film with fine performance, as well as the preparation method thereof and the purpose. The drug-loaded film takes chitosan, polyethylene glycol and ciprofloxacin hydrochloride as raw materials, and is formed by mixing the chitosan, the polyethylene glycol and the ciprofloxacin hydrochloride; the mass percent content of the polyethylene glycol in the blend drug-loaded film is 2 percent to 10 percent, the mass percent content of the ciprofloxacin hydrochloride is 3 percent to 15 percent, and the mass percent content of the chitosan is 80 percent to 95 percent. The preparation steps are as follows: the chitosan is dissolved in acetate solution with 1 percent to 2 percent of mass percent to obtain chitosan solution with 3 percent to 6 percent of mass percent, the polyethylene glycol is dissolved in distilled water to obtain polyethylene glycol solution with 3 percent to 6 percent of mass percent, according to the proportion with the mass ratio of chitosan: polyethylene glycol: ciprofloxacin hydrochloride being 8.3 to 9.5: 0.2 to 1: 0.3 to 1.5, the chitosan solution and the polyethylene glycol solution are evenly mixed with ciprofloxacin hydrochloride, after being filtered, decompressed and debubbled, the mixed solution is added with coagulation solution, and then the chitosan / polyethylene glycol blend drug-loaded film is prepared through the salivating evaporation method under the room temperature. The drug-loaded film can be widely applied to the fields such as medicine and food, etc., and is especially suitable for being used as a drug film for the wound dressing and the vivo release.
Owner:WUHAN UNIV
Preparation method of ciprofloxacin hydrochloride
InactiveCN101851198AReduce pollutionReduce generationOrganic chemistryAntiinfectivesIsoamyl alcoholCarboxylic acid
The invention discloses a preparation method of ciprofloxacin hydrochloride. The existing synthesis method generally uses isoamyl alcohol and the like as solvent, thus having the problems of strong smell, difficult biodegradation and higher environmental pollution. If the solvent such as the isoamyl alcohol and the like is used, more alkali insoluble substances and acidic insoluble substances are generated in recovery after the reaction, so that the insoluble substances are needed to be treated by purification through the steps such as alkali-dissolving heat-filtering call-back throw filter, acidic-dissolving heat-filtering call-back throw filter, salifying decoloration heat-filtering and the like, the process route is longer, and the product yield is lower. The preparation method of the ciprofloxacin hydrochloride selects the proper solvent as reaction medium, firstly leads cyclopropane carboxylic acid and piperazine to have piperazine reduction reaction and then leads the reaction product to be salified together with hydrochloric acid. In the reaction process, less alkali insoluble substances and acidic insoluble substances are generated in the reaction process, and the ciprofloxacin hydrochloride can be obtained by salifying decoloration heat-filtering, separation by crystallization, throw filter, rinsing and drying after being directly cooled and leached, so that the time for occupying equipment and the time of working procedures are shortened, and the production efficiency of a workshop is improved.
Owner:ZHEJIANG JINGXIN PHARMA +1
Disposable levofloxacin hydrochloride eye drops without bacteriostatic agent and preparation method thereof
InactiveCN101461778AAvoid side effectsAvoid potential dangerAntibacterial agentsOrganic active ingredientsLevofloxacinCiprofloxacin Hydrochloride
The invention discloses bacteriostat-free ciprofloxacin hydrochloride eye drops and a preparation method thereof. The bacteriostat-free ciprofloxacin hydrochloride eye drops comprise ciprofloxacin hydrochloride, a pH regulator, an isotonic agent, a stabilizing agent, a thickening agent, and the like; and the preparation method adopts a bacteria-free bottling process or an autoclaving process. In addition, the eye drops are independently packaged in disposable single dose, thereby the sterility performance of products is guaranteed and the products are more safe, reliable, simple, convenient, and sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY
Medicinal composition containing ciprofloxacin compound and preparation method thereof
InactiveCN102973565ASignificant clinical effectOvercoming therapeuticOrganic active ingredientsAerosol deliveryEthyl hydroxybenzoateBerberine
The invention relates to a medicinal composition containing ciprofloxacin compound and a preparation method thereof. The composition is cream, and consists of the following ingredients in percentage by weight: 0.3 to 0.4 percent of ciprofloxacin, 8.0 to 10.0 percent of berberine, 9.0 to 11.0 percent of mixed hexadecanol and octadecanol, 3.0 to 5.0 percent of liquid paraffin, 10.0 to 12.0 percent of albolene, 0.05 percent of ethyl p-hydroxybenzoate, 5.0 to 7.0 percent of glycerol, 1.45 to 1.55 percent of lauryl sodium sulfate, and 56.1 to 62.1 percent of purified water. The medicinal composition can effectively treat bedsore, and facilitates nursing. The medicinal composition has smooth appearance and no stimulation or anaphylaxis, is convenient to carry and use, brings comfort to a patient in the using process, and has the advantages of high effective rate, no relapse after cure, low cost and long storage period.
Owner:HEFEI YIFAN PHARMA MANAGEMENT
Preparation method of fly attractant containing agricultural antibiotic and application method thereof
InactiveCN104304326ANo pollutionTo achieve the purpose of direct insecticideBiocidePest attractantsAntibiotic YCiprofloxacin Hydrochloride
The invention discloses a preparation method of novel fly attractant. The attractant comprises brown sugar, fish meal, wheat bran, alphamethrin and animal ciprofloxacin. Attraction is produced on flies through odor produced by fermented brown sugar, fish meal and wheat bran; the alphamethrin added in the attractant can produce stomach action on the flies; ciprofloxacin can ensure that the quantity of eggs of fed adult flies is reduced; further double actions of rapid killing and continuous control can be produced on the flies. Compared with the prior art, the method has the advantages that fenolona can achieve the purpose of directly killing flies, ciprofloxacin reduces the production of eggs through physiological regulation and achieves the effect of continuous control, less pesticide is utilized, the environment is not polluted during the application process, and utilized residues can be applied to manure collection.
Owner:TAISHAN MEDICAL UNIV
Preparation method of ciprofloxacin hydrochloride tablets
InactiveCN107669645ASolve the fragileSolve the sticking problemAntibacterial agentsOrganic active ingredientsFiller ExcipientLow-substituted hydroxypropylcellulose
The invention relates to a preparation method of ciprofloxacin hydrochloride tablets, belonging to the technical field of pharmaceutical preparations. According to the preparation method of the ciprofloxacin hydrochloride tablets, ciprofloxacin hydrochloride is taken as a main material, a filling agent, a disintegrating agent and a lubricating agent are taken as auxiliary materials, and the ciprofloxacin hydrochloride tablets are prepared by adopting a direct powder compression process; the filling agent is a mixture of starch and one or two of lactose or microcrystalline cellulose; the disintegrating agent is one or two of crospovidone or low-substituted hydroxypropyl cellulose. The preparation method provided by the invention solves the problems of tablet cracking, sticking and picking,great dissolubility difference and the like, and is simple in technology, easy to implement and suitable for large-scale production.
Owner:REYOUNG PHARMA
Ciprofloxacin C3 amide derivative, preparation method thereof and application
ActiveCN106432076AThe synthesis method is simpleThe synthesis method is safeAntibacterial agentsOrganic active ingredientsEthyl chloroformateHydrogen
The invention discloses a ciprofloxacin C3 amide derivative, a preparation method thereof and an application. The ciprofloxacin C3 amide derivative is provided with a structure as shown in a formula (I). Ciprofloxacin hydrochloride is added into excessive methylene dichloride, triethylamine is dripped to adjust the pH (potential of hydrogen) of reaction liquid to be 7.5-8.5, an appropriate amount of ethyl chloroformate is added, the reaction liquid is subjected to return flow agitation at the temperature of 20 DEG C and is clear, triethylamine is dripped into the reaction liquid so that the pH of the reaction liquid is 7.5-8.5, arylamine is added, return flow is continued for 1-2 hours, and the reaction liquid is cooled, reduced pressure distillation and concentration to obtain a target product. The ciprofloxacin C3 amide derivative has good sonodynamic activity and is obviously superior to ciprofloxacin in terms of microwave synergistic antibacterial effect.
Owner:LIAONING UNIVERSITY
Method for detecting content of ciprofloxacin
ActiveCN102928393AEasy to operateQuick analysisFluorescence/phosphorescenceFluoProbesFluorescent quenching
The invention discloses a method for detecting the content of ciprofloxacin, which comprises the steps of: mixing a ciprofloxacin solution and a fluorescent probe solution, detecting the fluorescent intensity of a mixture, calculating a differential value of fluorescence intensity before and after the mixing, and obtaining the content of ciprofloxacin according to the differentia value and a preset standard curve. The method provided by the invention applies the fluorescent probe solution, the fluorescent probe consists of a terephthalaldehyde-o-aniline thiophenol Schiff base solution and a manganese chloride aqueous solution, and the content of ciprofloxacin is detected through a fluorescence spectrophotometry due to the fact that the quenching function of ciprofloxacin on the fluorescent light of the fluorescent probe solution and positive correlation between the degree of the fluorescent quenching and the concentration of ciprofloxacin. The method provided by the invention is simple to operate, fast to analyze, stable in system and good in reproducibility.
Owner:HAINAN HERUI PHARMA
Ciprofloxacin effervescent tablet for control of silkworm bacterial disease
InactiveCN104224744APrevent neutralizationAntibacterial agentsOrganic active ingredientsDiseaseCiprofloxacin lactate
The invention discloses a ciprofloxacin effervescent tablet for control of a silkworm bacterial disease and a preparation method. The effervescent tablet is used for controlling the silkworm bacterial disease and comprises the following components: ciprofloxacin (comprising ciprofloxacin hydrochloride or ciprofloxacin lactate), an acid source disintegrating agent, an alkali source disintegrating agent and an adhesion agent. Meanwhile, the invention further discloses the preparation method of the effervescent tablet. The preparation method disclosed by the invention is simple in process and low in cost; the prepared effervescent tablet is accurate in dosage and convenient to use, and capable of being applied to the control of the silkworm diseases.
Owner:严相顺
Preparation method of chitosan-loaded ciprofloxacin microsphere
InactiveCN112137985ALow costSimple processAntibacterial agentsOrganic active ingredientsMicrosphereCiprofloxacin Hydrochloride
The invention discloses a preparation method of a chitosan-loaded ciprofloxacin microsphere. The preparation method comprises the following steps: ultrasonically dissolving chitosan and ciprofloxacinhydrochloride in an acetic acid solution to obtain a solution 1, ultrasonically dissolving span-80 in liquid paraffin to obtain a solution 2, mixing the solution 1 and the solution 2 according to a volume ratio of the liquid paraffin to the acetic acid solution of 3:1-4:1 and a mass ratio of span-80 to chitosan of 25:2, performing stirring and emulsifying at 40-60 DEG C, slowly dropwise adding a glutaraldehyde solution, and performing stirring and cross-linking to obtain the chitosan-loaded ciprofloxacin microsphere. The chitosan-loaded ciprofloxacin microsphere prepared the method has a relatively smooth surface, and a particle size uniformly distributed between 1 [mu]m and 5 [mu]m, and has good antibacterial property and slow-release performance.
Owner:NANJING UNIV OF SCI & TECH
Silkworm disease preventing and treating medicine and its prepn
InactiveCN1383826AReduce efficacyImprove antibacterial propertiesOrganic active ingredientsBiocideDiseaseDistilled water
The silkworm diseases preventing and treating medicine is compounded with Ciprofloxacin hydrochloride and distilled water in the weight ratio of 5-50 to 600-950. During its compounding, Ciprofloxacinhydrochloride is first dissolved with distilled water and then diluted with distilled water to requied concentration while stirring and the medicine solution is bottled. The present invention has excellent antiseptic and internal bacteriostatic effect and may be used in treating several bacterial silkworm diseases. It is diluted to 250 times and the diluted medicine solution has a bacterial silkworm disease preventing effect as high as 95-100 %; or it is diluted to 500 times and the diluted medicine solution has a bacterial silkworm disease treating effect as high as 90-98%.
Owner:HUASHENG SILK JUXIAN COUNTY
Hydrochloric acid ciprofloxacin lipidosome preparation and preparation method thereof
InactiveCN105232464AHigh encapsulation efficiencyLong retention timeAntibacterial agentsOrganic active ingredientsCholesterolPhosphate
The invention discloses a preparation method of a hydrochloric acid ciprofloxacin lipidosome preparation. The preparation method includes the steps that one part of hydrochloric acid ciprofloxacin is weighed, a phosphate buffer solution is added and stirred, and a hydrochloric acid ciprofloxacin solution is obtained; 2, blank liposome is prepared, wherein 10-50 parts of soya bean lecithin and 5-40 parts of cholesterol are weighed and mixed, chloroform is added and stirred for being dissolved, decompression is conducted for removing solvent, and a blank phospholipid membrane is prepared; 3, the membrane is dissolved through a small amount of chloroform, the hydrochloric acid ciprofloxacin solution obtained in step 1 and the phosphate buffer solution are taken for being added into an acetate solution, ultrasound treatment is conducted for 10-30 minutes through a bath type ultrasonic instrument at the temperature of 45-60 DEG C, a stable solution is formed, the obtained lipidosome solution is filtered twice through a microfiltration membrane, granulation is conducted, and the hydrochloric acid ciprofloxacin lipidosome preparation is obtained. The lipidosome produced through the ultrasonic instrument has the advantages that the particle size is small, particle size distribution is narrower, and the lipidosome has good preparation nature and target ability, can improve the curative effect, has a long-term effect, can reduce drug toxicity and can improve the drug stability.
Owner:ZHENGZHOU HOUYI PHARMA
Novel method for preventing and controlling black blight type epidemic disease of mulberry
The invention discloses a control method of epidemic disease of leaf blight and fruit rot of mulberry leaf. The technical proposal of the method is that ciprofloxacin is mixed with water to have a concentration of 90 -110mg / kg, and, in early stage of disease incidence when the symptom is just shown, the mixed ciprofloxacin is sprayed onto the mulberry leaves by a dosage of 45-55kg per 667 square meter (1mu) after sick bud leaves are picked off, and the mulberry leaves can be used for feeding silkworm on the day the method is applied. Another technical proposal of the invention is that enrofloxacin hemihydrate is mixed with water to have a concentration of 90-110mg / kg, and, in early stage of disease incidence when the symptom is shown, the mixture is sprayed onto the mulberry leaves by a dosage of 45-55kg per 667 square meter (1mu) after sick bud leaves are picked off, and the mulberry leaves can be used for feeding silkworm on the day the method is applied. The invention has simple preparing method, wide raw material sources, low cost, innocuity, no-residue and no pollution, and can be used conveniently by directly being sprayed onto the mulberry leaves; besides, the sprayed mulberry leaves can be picked off for feeding silkworm. Tests indicate that the method has control efficiency of 90 percent, and can control damage effectively when applied to mulberry fields covering an area of 100 hectare.
Owner:蔡国祥
Method for detecting dimethyl sulfate contained in ciprofloxacin hydrochloride
ActiveCN111855843AGood precisionStrong specificityComponent separationAgainst vector-borne diseasesGas liquid chromatographicPolyethylene glycol
The invention provides a method for detecting dimethyl sulfate contained in ciprofloxacin hydrochloride. The method comprises the following step: detecting a ciprofloxacin hydrochloride test solutionby adopting a gas chromatograph provided with an FPD detector, a chromatographic column of the gas chromatograph being a chromatographic column filled with polyethylene glycol, the initial column temperature being 70 + / -1 DEG C, and the flow rate of the ciprofloxacin hydrochloride test solution being 2.0 + / -0.05 mL / min. The detection method provided by the invention does not need derivatization, and has the advantages of no interference, high signal-to-noise ratio, good precision and simple detection operation.
Owner:武汉九州钰民医药科技有限公司
Veterinary drug for treating bacterial disease of fowl
The invention discloses a veterinary drug for treating bacterial disease of fowl, and is characterized in that the veterinary drug comprises ciprofloxacin hydrochloride, vitamin C and glucose. The inventive veterinary drug can effectively treat bacterial diseases of fowl, has evident curative effect and convenient application, and deserves wide generalization.
Owner:王洪涛
Compound ciprofloxacin injection for animal and its preparing process
InactiveCN1985827AImprove the bactericidal effectStrong effect on Gram-negative bacteriaAntibacterial agentsPill deliveryDiseaseIntestinal tract diseases
The present invention is compound ciprofloxacin injection for animal and its preparation. The compound ciprofloxacin injection consists of main medicine components comprising ciprofloxacin lactate or ciprofloxacin hydrochloride 2.5-10 wt% and mequindox 1-4 wt%; additive comprising antioxidant 0.1-0.2 wt% and metal complexing agent 0.01-0.02 wt%; and solvent in 86-96.5 wt%. The present invention provides one new veterinary medicine for treating animal's intestinal tract diseases and has the advantages of reasonable recipe, stable preparation, high bioavailability, determined curative effect, etc.
Owner:江西百思技术咨询有限公司
Bismuth tungstate catalyst and preparation method thereof as well as application of combined ultrasound to catalysis and degradation of antibiotics
InactiveCN108543532AThe synthesis method is safeEfficient synthesisWater/sewage treatment with mechanical oscillationsWater contaminantsTungstateSynthesis methods
The invention discloses a bismuth tungstate catalyst and a preparation method thereof as well as application of combined ultrasound to catalysis and degradation of antibiotics. A hydrothermal synthesis method is adopted to synthesize the bismuth tungstate catalyst with a square plate-shaped crystal form under the condition that the pH value is equal to 5. A catalyst synthesis method is simple, convenient, safe, and easy for post-treatment. The degradation rate of a ciprofloxacin hydrochloride water solution catalyzed and degraded by a catalyst and ultrasonic combination sound is greater than that of a ciprofloxacin hydrochloride water solution independently degraded by bismuth tungstate, and the bismuth tungstate has better sound catalytic activity. The bismuth tungstate is used for catalysis and ultrasonic degradation of the ciprofloxacin hydrochloride water solution so as to enable the degradation efficiency of the ciprofloxacin hydrochloride water solution to be improved, and the bismuth tungstate catalyst has guiding significance for the synthesis of a more effective sound catalysis nano material.
Owner:LIAONING UNIVERSITY
Ciprofloxacin hydrochloride oral solid preparation and preparation process thereof
InactiveCN104188893AImprove bioavailabilityEnsure medication safetyOrganic active ingredientsPharmaceutical delivery mechanismMethyl celluloseCiprofloxacin Hydrochloride
The invention relates to a ciprofloxacin hydrochloride oral solid preparation and a preparation process thereof. The oral solid preparation contains ciprofloxacin hydrochloride, hydroxypropyl methyl cellulose, a disintegrating agent and a lubricant. The preparation process comprises the following steps: dissolving the ciprofloxacin hydrochloride and the hydroxypropyl methyl cellulose in water and carrying out spray drying so as to obtain a dispersion body; evenly mixing the dispersion body with the disintegrating agent and the lubricant; filling the obtained mixture in a capsule shell or pressing the obtained mixture to form a tablet. The oral solid preparation is stable under an alkaline condition, and can be used for effectively avoiding the problem that the ciprofloxacin hydrochloride is separated out in an alkaline intestinal environment.
Owner:赵明亮
Preparation method of zinc stannate nanocube/graphene aerogel sunlight catalyst for degrading ciprofloxacin hydrochloride wastewater
InactiveCN109675546AAddressing the downside of difficult recyclingGood chemical stabilityWater/sewage treatment by irradiationWater treatment compoundsSolar photocatalysisWastewater
The invention discloses a preparation method of a zinc stannate nanocube / graphene aerogel sunlight catalyst for degrading ciprofloxacin hydrochloride wastewater, and belongs to the technical field ofsynthesis of natural sunlight response photocatalytic materials. Graphene is used as a base material to be compounded with the nanocube zinc stannate to obtain a high-activity zinc stannate / graphene aerogel photocatalysis material, the zinc stannate nanocube / graphene aerogel sunlight catalyst has the characteristic of high degradation efficiency on the antibiotic ciprofloxacin hydrochloride undernatural sunlight irradiation, and the preparation method is a novel method for obtaining the high-activity photocatalyst through a simple preparation process.
Owner:HENAN NORMAL UNIV
Fertilizer composition for preventing and curing kiwifruit canker and preparation method thereof
Owner:贵州三福生物科技有限公司 +1
A kind of preparation method of magnetic chitosan composite microsphere adsorbent
InactiveCN103920472BEasy to makeImprove thermal stabilityOther chemical processesWater contaminantsMicrosphereSorbent
The invention relates to a preparation method of a magnetic chitosan composite microsphere adsorbent, which belongs to the technical field of environmental material preparation. Using FeCl3 6H2O and FeCl2 4H2O as raw materials, nano-Fe3O4 was prepared by co-precipitation method, then using glutaraldehyde as cross-linking agent, Fe3O4, kaolin and chitosan as raw materials, the magnetic chitosan composite was synthesized by emulsification cross-linking method Microsphere adsorbent, and use it for the separation of ciprofloxacin hydrochloride in water environment. Static adsorption experiments were used to study the adsorption and kinetic properties of the prepared adsorbents. The results show that the magnetic chitosan composite microsphere adsorbent obtained by the present invention has fast adsorption kinetic properties, high adsorption capacity and fast magnetic separation efficiency.
Owner:JIANGSU UNIV
Preparation method of ciprofloxacin lactate
The invention belongs to the technical field of medicine preparation and particularly relates to a preparation method of ciprofloxacin lactate. The method comprises the steps as follows: mixing ciprofloxacin hydrochloride with a solvent, adjusting pH with alkali, and performing cooling crystallization, filtration, drying and other steps to obtain ciprofloxacin; mixing ciprofloxacin with the solvent, adding a salt forming agent for a salt forming reaction, and then performing cooling crystallization, filtration, drying and other steps to obtain a finished product of ciprofloxacin lactate. The preparation method is simple to operate, the involved reaction condition is mild and easy to control, ciprofloxacin lactate is prepared in two steps, the refining process is omitted, the production cycle is shortened, the cost is greatly reduced, and the mass yield of ciprofloxacin lactate reaches 95% or higher, and the product purity can reach 99.5%.
Owner:HENAN KANGDA PHARMA
Method for degrading antibiotic ciprofloxacin hydrochloride
InactiveCN108394956AWater/sewage treatment with mechanical oscillationsWater contaminantsCavitationSemiconductor materials
The invention discloses a method for degrading antibiotic ciprofloxacin hydrochloride, and relates to a method for degrading antibiotics. By use of a hydro-thermal synthesis method, a tungstate semiconductor material CaWO4 is prepared and is cooperated with an ultrasonic technology for catalyzing medicine preparation waste water simulated by the ultrasonic degradation ciprofloxacin hydrochloride.The ultrasonic degradation is an efficient processing method, which is newly developed at the beginning of 1990, for degrading organic pollutants, and the principle of the processing method is that organic matters are degraded and mineralized by a cavitation effect generated by ultrasound in solution media. Therefore, the cavitation effect of the ultrasonic wave and physical and chemical changes initiated by the cavitation are the root cause of organic matter ultrasonic degradation. The cavitation effect of the ultrasonic wave and physical and chemical changes initiated by the cavitation are combined to degrade the antibiotic ciprofloxacin hydrochloride, and the feasibility of the technology is provided by researches. An experiment proves that the technology has a good effect on the aspectof the ultrasonic degradation of antibiotic wastewater.
Owner:SHENYANG INSTITUTE OF CHEMICAL TECHNOLOGY
Method for treating ciprofloxacin hydrochloride in water
InactiveCN104761019AHigh removal rateGood synergyWater/sewage treatment by irradiationGamma irradiationWastewater
The invention belongs to the technical field of water treatment, discloses a method for treating ciprofloxacin hydrochloride in water, and in particular relates to a method for degrading ciprofloxacin hydrochloride in water by virtue of gamma irradiation. According to the method, 60Co is used as a gamma irradiation source, the irradiation dose is 50-5000Gy, the concentration of ciprofloxacin hydrochloride in the water is 0.05-100mg.L<-1>, the ciprofloxacin hydrochloride in the water can be efficiently degraded, and secondary pollution is not generated, so that the method is safe and reliable and has good development prospect. The method can be used together with Cr<6+> and / or BrO3<-> to ensure that the degradation efficiency of ciprofloxacin hydrochloride can be improved and the degradation efficiency of Cr<6+> and BrO3<-> can also be improved, so that a new solution is provided for comprehensive treatment of wastewater of different sources.
Owner:NANJING UNIV OF INFORMATION SCI & TECH
Chitosan/silk fibroin/chitosan microsphere-ciprofloxacin (CS/SF/CMs) anti-microbial composite scaffold for promoting seawater immersion wound healing and preparation method for anti-microbial composite scaffold
ActiveCN111150887APromote healingGood drug sustained release performanceProsthesisFreeze-dryingCross linker
The invention discloses a preparation method for a chitosan / silk fibroin / chitosan microsphere-ciprofloxacin (CS / SF / CMs) anti-microbial composite scaffold for promoting seawater immersion wound healing. The method comprises the specific steps that a chitosan solution and a silk fibroin solution are mixed, ciprofloxacin-encapsulated chitosan drug-loaded microspheres CMs-CIP are added, uniform mixingis performed, a cross-linking agent is added, and freeze drying is performed after overnight cold storage to obtain the CS / SF / CMs anti-microbial composite scaffold. The anti-microbial composite scaffold is a superior material for treating a seawater immersion wound; the anti-microbial composite scaffold is of a uniform porous net structure, can absorb wound exudates to keep a suitable moisture environment for the wound, and increases contact area between the wound and outside oxygen to promote wound healing; the anti-microbial composite scaffold can also slowly release CIP to avoid side effects caused by burst release; and the released CIP has a broad-spectrum antibacterial property, and can resist wound infections.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT)
Ciprofloxacin dry powder inhaler and preparation method thereof
ActiveCN108771660AFluffy cotton-like structureHigh emptying rateAntibacterial agentsOrganic active ingredientsSpidroinMannitol
The invention discloses a ciprofloxacin dry powder inhaler and a preparation method thereof. The dry powder inhaler is prepared from a drug and a binary auxiliary material, wherein the drug accounts for 80 to 20 percent by mass of the dry powder inhaler, the binary auxiliary material accounts for 20 to 80 percent by mass of the dry powder inhaler, and the binary auxiliary material comprises a mucus diluting agent and biological adhesive protein; the mucus diluting agent is at least one of mannitol, ambroxol hydrochloride, aminothiopropionic acid, and bromhexine hydrochloride; and the biological adhesive protein is at least one of silk fibroin, albumin or spidroin. The dry powder inhaler prepared by the invention is good in mobility, good in aerodynamic performance, capable of targeting thedrug to lung and capable of effectively increasing the local concentration of the drug, has mucus diluting and biological mucosa adsorption characteristics, and is particularly suitable for a patientwith bronchiectasia caused by the chronic infection of the lung.
Owner:SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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