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Compound ciprofloxacin injection for animal and its preparing process

A technology of ciprofloxacin and ciprofloxacin lactate, which is applied to non-active ingredient medical preparations, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the economic losses of farmers, unsatisfactory curative effects, Untimely treatment and other problems, to achieve unique curative effect, good antibacterial effect, accurate dosage effect

Inactive Publication Date: 2007-06-27
江西百思技术咨询有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Intestinal diseases of livestock and poultry are prone to onset, seriously affecting their growth, untimely treatment, high mortality, and causing huge economic losses to farmers
At present, the veterinary clinical treatment of livestock and poultry intestinal diseases is generally a single preparation, and most of the curative effects are not satisfactory.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Ciprofloxacin Lactate 5% Acephrine 2%

[0010] The preparation process of the present invention is as follows: separately weighing the prescription amounts of ciprofloxacin lactate and acemetaquine, adding dimethylacetamide, dimethylformamide, polyethylene glycol and water for injection to a total volume of 60%, and stirring Dissolve; then add the prescription amount of sodium bisulfite 0.2%, disodium ethylenediaminetetraacetic acid 0.01%, stir to dissolve; add water for injection to the full volume, adjust the pH value, filter, potting, and sterilize at 100°C for 30 minutes, Cooling, light inspection, printing, packaging, ready to go.

Embodiment 2

[0012] Ciprofloxacin Hydrochloride 5% Acephal 2%

[0013] The preparation process of the present invention is as follows: respectively weighing the prescription amounts of ciprofloxacin hydrochloride and acemetaquine, adding dimethylacetamide, dimethylformamide, polyethylene glycol, and water for injection to a total volume of 60%, and stirring Dissolve; then add the prescription amount of sodium bisulfite 0.2%, disodium ethylenediaminetetraacetic acid 0.01%, stir to dissolve; add water for injection to the full volume, adjust the pH value, filter, potting, and sterilize at 100°C for 30 minutes, Cooling, light inspection, printing, packaging, ready to go.

Embodiment 3

[0015] Ciprofloxacin Lactate 2.5% Acephrine 1%

[0016] The preparation process of the present invention is as follows: separately weighing the prescription amounts of ciprofloxacin lactate and acemetaquine, adding dimethylacetamide, dimethylformamide, polyethylene glycol and water for injection to a total volume of 60%, and stirring Dissolve; add sodium sulfite 0.1%, disodium ethylenediaminetetraacetic acid 0.01%, and dissolve by stirring; add water for injection to full volume, adjust pH, filter, potting, sterilize at 100°C for 30 minutes, cool, and light Inspection, printing, packaging, ready-to-get.

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PUM

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Abstract

The present invention is compound ciprofloxacin injection for animal and its preparation. The compound ciprofloxacin injection consists of main medicine components comprising ciprofloxacin lactate or ciprofloxacin hydrochloride 2.5-10 wt% and mequindox 1-4 wt%; additive comprising antioxidant 0.1-0.2 wt% and metal complexing agent 0.01-0.02 wt%; and solvent in 86-96.5 wt%. The present invention provides one new veterinary medicine for treating animal's intestinal tract diseases and has the advantages of reasonable recipe, stable preparation, high bioavailability, determined curative effect, etc.

Description

Technical field [0001] The invention relates to a veterinary compound ciprofloxacin injection for treating intestinal diseases of livestock and poultry and a preparation process thereof. Background technique [0002] The compound ciprofloxacin injection, which is made from the two main medicines of ciprofloxacin lactate, ciprofloxacin hydrochloride, and methaquine, is effective in the treatment of yellow diarrhea, white diarrhea and clostridia ); lamb dysentery; calf diarrhea; livestock necrotizing enteritis, dysentery, paratyphoid; chick pullorum, chicken colibacillosis, avian typhoid and other intestinal diseases have significant effects. Intestinal diseases of livestock and poultry are prone to disease, which seriously affects their growth, is not treated in time, and has a high mortality rate, causing huge economic losses to farmers. At present, veterinary medicines for the treatment of intestinal diseases of livestock and poultry are generally single preparations, and most o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/496A61K9/20A61K47/34A61K47/16A61P31/04A61K31/47A61K47/10A61K47/18
Inventor 胡少平张克曾标其
Owner 江西百思技术咨询有限公司
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