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45 results about "Ciprofloxacin lactate" patented technology
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Ciprofloxacin Lactate is a medicine that is used for the treatment of Bacterial infections and other conditions. The complete list of uses and indications for Ciprofloxacin Lactate is as follows: Bacterial infections. Ciprofloxacin Lactate may also be used for purposes not listed here.
Fertilizer and pesticide combination reagent for preventing and killing bacterial canker of kivifruit and preparation method of fertilizer and pesticide combination
ActiveCN104628481AHigh affinityHigh activityNitrogenous fertilisersFertilizer mixturesLiquid productFermentation
The invention discloses a fertilizer and pesticide combination reagent for preventing and killing bacterial canker of kiwifruit and a preparation method of the fertilizer and pesticide combination reagent. The fertilizer and pesticide combination reagent is prepared from the following raw materials in parts by weight: 200 parts of agricultural amino acid water soluble powder, 40-50 parts of anhydrous zinc chloride, 45-65 parts of anhydrous manganese chloride, 40-80 parts of a ciprofloxacin active compound or a ciprofloxacin active compound, 100-200 parts of a 14% methyl chloride isothiazolinone water agent, 100-150 parts of oxine-copper active compound, 0.1 part of forchlorfenuron, 0.1 part of a 5-nitroguaiacol sodium salt active compound, 0.5 part of an alpha-pimacol active compound, 350-450 parts of molasses microbial fermentation concentrate solution, 0.2-0.25 part of sodium polyacrylate powder, 50-60 parts of No.YD-7 liquid fertilizer synergia solution, 0.1-0.2 part of industrial alcohol and the balance of deionized water to supplement the raw materials to 1200-1250 parts. The fertilizer and pesticide combination reagent disclosed by the invention is a high-density liquid product with fertilizer and pesticide effects, has good affinity for both water and plants, mainly contact and kill plant bacteria, and can also kill pathogenic fungus. A layer of compact organic pesticide and fertilizer film is formed outside a tree body when the fertilizer and pesticide combination reagent is applied in large concentration, and a sustained release function is exerted.
Owner:贵州三福生物科技有限公司 +1
Traditional Chinese medicine and western medicine compound infusion liquid for preventing and treating endometritis of dam and preparing method thereof
InactiveCN102000145AImprove antibacterial propertiesIncrease lethalityAntibacterial agentsSalicyclic acid active ingredientsCiprofloxacin lactateSide effect
The present invention discloses a traditional Chinese medicine and western medicine compound infusion liquid for preventing and treating endometritis of dam and preparing method thereof, wherein the contents of various constituents are as follows: 0.5-5g / L of safflower extract, 1-10g / L of epimedium extract, 1-10g / L of leonurus extract, 5-50g / L of Maquinox, 10-100g / L of salicylic acid, 4-40g / L of Ciprofloxacin Lactate, 3-30g / L of metronidazole, 1-10g / L of borneol, 20-40g / L of polyvinylpyrrolidone, 100-200g / L of ethanol and 5-15g / L of tween-80, the rests are water for injection. In the present invention, the effective combination of traditional Chinese medicine and western medicine overcomes the shortages of big dosage, high dosing strength, becoming effective slowly and long course of treatment in pure traditional Chinese treatment, and the shortages of big side-effects and easily generated resistance in pure western medicine treatment. Symptoms and root causes are all treated, and the organic combination of antibacterial inflammation of antibiotics and repairing uterine function by traditional Chinese medicine ingredients is realized.
Owner:南京日升昌生物技术有限公司
Novel technique of preparing lactic acid ciprofloxacin injection
ActiveCN101108163AStable release rateReduce labor intensity of injectionAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateHydrophilic polymers
Owner:PU LIKE BIO ENG +2
Veterinary ciprofloxacin lactate injection and preparation method thereof
InactiveCN102697725AEasy to useReduce stress responseAntibacterial agentsOrganic active ingredientsAnimal scienceCiprofloxacin lactate
The invention relates to the technical field of veterinary administration, in particular to a veterinary ciprofloxacin lactate injection. The veterinary ciprofloxacin lactate injection consists of the following components in percentage by weight: 4-10 percent of ciprofloxacin lactate counted by ciprofloxacin, 10-15 percent of polyoxyethylene 40 hydrogenated castor oil, 0.5-1.0 percent of carbomer, 0.1 percent of sodium bisulfite, 0.01 percent of ethylene diamine tetraacetic acid, and the balance of water for injection. The injection is convenient to use; compared with the conventional injection, the veterinary ciprofloxacin lactate injection has the advantages: the injection times are reduced from twice a day to once a day, treatment cost is saved, stress caused by repeated injection for animals is reduced, and medicament tolerance of bacteria is avoided; the veterinary ciprofloxacin lactate injection has low toxicity and a reliable curative effect, acts for a long time, and can be used for effectively treating white scour of piglets and white diarrhea; and the swine muscle injection half-life period is 22.96 hours, which is equivalent to five times that of an ordinary injection (4.6 hours).
Owner:山东省健牧生物药业有限公司
Compound formulation for treating bacterial infection of digestive tract of livestock and poultry and preparation method of compound formulation
ActiveCN103721240APrevent dehydrationRestore appetiteAntibacterial agentsDigestive systemCiprofloxacin lactateFood formulation
The invention relates to the field of veterinary drug formulations, and in particular relates to a compound formulation for treating bacterial infection of the digestive tract of livestock and poultry. The compound formulation comprises the following components in every 100ml: 2-10g of ciprofloxacin on ciprofloxacin basis, 1-9g of colistin sulfate on synthesized pure medicine, and 0.03-0.1g of atropine sulfate. The compound formulation is prepared by adopting ciprofloxacin and colistin sulfate with high bacteria sensitivity and strong synergetic bacteria resistance and combining symptomatic treatment medicines by a method for treating both symptom and root cause, so that a remarkable synergetic sterilization effect can be achieved, the drug dosage can be reduced, the cure rate can be improved, the treatment cost can be reduced, and the compound formulation is stable; occurrence of drug resistance of pathogenic bacteria of the digestive tract of livestock and poultry can be effectively avoided; the compound formulation is low in prescription price and convenient to popularize and apply.
Owner:湖南慧谷农业生态研究院有限公司
A kind of preparation method of ciprofloxacin lactate sodium chloride injection
InactiveCN102274169AImprove solubilityGuaranteed stabilityAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateFiltration
The invention relates to a preparation method of ciprofloxacin lactate and sodium chloride injection, which comprises the steps of concentrated preparation, heating, filtration, dilution, adjustment of pH value, filtration, filling, sealing, sterilization, inspection and the like. The ciprofloxacin lactate sodium chloride injection prepared by the preparation method has good stability and can be packaged in plastic bottles.
Owner:ANHUI GLOBAL PHARM CO LTD
Ciprofloxacin thermo-sensitive type in-situ gel composition and preparing method thereof
ActiveCN103156805ASatisfy mobilityNo medication dead endsAntibacterial agentsOrganic active ingredientsSodium acetateCiprofloxacin lactate
The invention discloses ciprofloxacin thermo-sensitive type in-situ gel composition and belongs to the field of veterinary drug preparations. The thermo-sensitive type in-situ gel composition comprises, by weight volume (g / ml), 5%-10% of ciprofloxacin, 20%-26% of poloxamer 407, 0.5%-10% of poloxamer 188, 0.01%-0.04% of edetic acid, 0.009%-0.03% of bacteriostatic agent, and 0.1%-0.2% of antioxidant. Solvent of the composition is acetic acid - sodium acetate buffer solution. The invention further discloses a preparing method of the composition. The ciprofloxacin thermo-sensitive type in-situ gel composition is liquid at room temperature, jelling temperature is close to body temperature, and therefore dosing is convenient and jelling speed is high, jelling strength and adhering function are good, the dosing can be achieved with accurate positioning, and loss of drug is reduced. Furthermore, the ciprofloxacin thermo-sensitive type in-situ gel composition and the preparing method thereof have controlled-releasing and long-acting functions, dosage is low, the number of times of dosing is small, harm caused by implants normally used is avoided, and pain of patients is relieved.
Owner:NANJING AGRICULTURAL UNIVERSITY +1
Veterinary ciprofloxacin injection and preparation method thereof
ActiveCN105147598AImprove stabilityNo precipitationAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateSodium bisulfate
The invention belongs to the technical field of veterinary preparations and discloses a veterinary ciprofloxacin injection and preparation method thereof. The injection (per 1000ml) is composed of 25.5-127.5g of ciprofloxacin, 50-150g of PVP-K, 50-100g of nicotinamide, 5-15g of sodium chloride, 0.5-5g of sodium bisulfate, 2-10g of lactic acid and the rest of water for injection. The veterinary ciprofloxacin injection has the advantages that stability of the veterinary ciprofloxacin injection under the low-temperature condition (0-5 DEG C) can be improved, and action time of the ciprofloxacin can be prolonged.
Owner:浙江大飞龙动物保健品股份有限公司
Ciprofloxacin effervescent tablet for control of silkworm bacterial disease
InactiveCN104224744APrevent neutralizationAntibacterial agentsOrganic active ingredientsDiseaseCiprofloxacin lactate
The invention discloses a ciprofloxacin effervescent tablet for control of a silkworm bacterial disease and a preparation method. The effervescent tablet is used for controlling the silkworm bacterial disease and comprises the following components: ciprofloxacin (comprising ciprofloxacin hydrochloride or ciprofloxacin lactate), an acid source disintegrating agent, an alkali source disintegrating agent and an adhesion agent. Meanwhile, the invention further discloses the preparation method of the effervescent tablet. The preparation method disclosed by the invention is simple in process and low in cost; the prepared effervescent tablet is accurate in dosage and convenient to use, and capable of being applied to the control of the silkworm diseases.
Owner:严相顺
Method for preparing ciprofloxacin lactate sodium chloride injection
ActiveCN102716072AFix stability issuesSolve solubilityAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateHydrogen
The invention provides a method for preparing ciprofloxacin lactate sodium chloride injection, and belongs to the field of medicinal preparation. The method includes the steps: firstly, dissolving lactic acid and sodium hydroxide into water for injection to prepare lactic acid solution; secondly, sufficiently mixing ciprofloxacin serving as a raw material, edetate disodium, diluted hydrochloric acid and the water for injection to prepare ciprofloxacin solution; and finally, sufficiently mixing the prepared lactic acid solution and the prepared ciprofloxacin solution, adding sodium chloride for injection into the solution, mixing the sodium chloride with the solution, and adjusting the pH (potential of hydrogen) value, adjusting the volume, pre-filtering, degerming, filling and sealing and performing autoclaved sterilization, inspection and the like to prepare the ciprofloxacin lactate sodium chloride injection. The method has the advantages of simple and convenient process, no environmental pollution, low cost and the like, and the ciprofloxacin lactate sodium chloride injection prepared by the method is high in stability and quality.
Owner:GUANGZHOU NANXIN PHARMA
Antibacterial compound herbal cream and preparation method thereof
InactiveCN109331098ACertain curative effectNo side effectsAntibacterial agentsHeavy metal active ingredientsDiseaseMenthol
The invention discloses antibacterial compound herbal cream and a preparation method thereof. The compound herbal cream is prepared from effective components in parts by mass as follows: 5-20 parts ofcamellia oil, 10-25 parts of herba violae, 30-60 parts of cortex pseudolaricis, 10-30 parts of nidus vespae, 30-60 parts of folium artemisiae argyi, 20-55 parts of radix sophorae flavescentis, 30-65parts of flos lonicerae, 10-35 parts of aloe, 10-25 parts of radix gentianae, 10-30 parts of radix polygoni multiflori, 2-10 parts of lithargyrum, 1-15 parts of menthol, 1-8 parts of borneol, 5-15 parts of chlorhexidine acetate and 5-16 parts of ciprofloxacin lactate. The antibacterial compound herbal cream has definite curative effect, treats both symptoms and root causes, has no side effects, can be used for a long time and can treat skin diseases such as skin itching and erythema caused by skin infection.
Owner:江西肤宝生物科技有限公司
Sticktight-containing compound composition for treating bacterial diarrhoea of livestock and poultry
ActiveCN102488767ALow priceDelay drug resistanceAntibacterial agentsDigestive systemCiprofloxacin lactateDiarrhoea symptoms
The invention discloses a sticktight-containing compound composition for treating bacterial diarrhoea of livestock and poultry. The compound composition is characterized by comprising raw materials of, by weight, 3-15 parts of lactic acid ciprofloxacin, 0.02-0.2 part of atropine sulfate, 20-70 parts of sticktight, 20-40 parts of rhizoma atractylodis, 8-20 parts of dark plum and 5-10 parts of myrobalan. The compound composition is prepared by mixing well the raw materials according to the proportion. An addition into an animal fodder is 0.1%-0.8%. The composition of the invention can kill bacteria rapidly and alleviate diarrhoea symptom caused by bacteria rapidly, has good protective effect on intestinal tract and overcomes disadvantages of a simple western medicine, such as long curative effect, weak curative effect, slow symptom alleviation and disadvantage of slow effect performance of a simple traditional Chinese medicine; besides, usage of the composition has low medicine cost and creates high benefit for farmers. The composition can be prepared into a powder, an oral liquid, a particulate agent and a tablet.
Owner:广西南宁市桃源兽药厂
Medicinal composition for treating pullorum disease and preparation method thereof
InactiveCN101926846AWide variety of sourcesLow priceAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateSophora Root
The invention belongs to the technical field of pullorum disease treatment and discloses a medicinal composition for treating pullorum disease and a preparation method thereof. The medicinal composition is prepared from the following raw material medicaments: 600 to 800 grams of common andrographis herb, 200 to 400 grams of lightyellow sophora root and 40 to 80 grams of ciprofloxacin lactate. In the invention, the ciprofloxacin lactate is directly added in an recommended amount to produce a remarkable treatment pullorum disease effect together with the common andrographis herb and lightyellow sophora root; and the ciprofloxacin lactate has high antibacterial activity, so the germ medicament resistance problem, which becomes increasingly serious nowadays, is solved. The medicament of the invention has the advantages that: the medicament materials are widely available and cheap; extraction solvent, which is water, is cheap; harm to chickens is avoided; the clinic symptoms of chickens infected with pullorum disease by human can be controlled effectively; and death rate of chickens is reduced obviously.
Owner:HENAN XINZHENGHAO BIO ENG
Compound ciprofloxacin injection for animal and its preparing process
InactiveCN1985827AImprove the bactericidal effectStrong effect on Gram-negative bacteriaAntibacterial agentsPill deliveryDiseaseIntestinal tract diseases
The present invention is compound ciprofloxacin injection for animal and its preparation. The compound ciprofloxacin injection consists of main medicine components comprising ciprofloxacin lactate or ciprofloxacin hydrochloride 2.5-10 wt% and mequindox 1-4 wt%; additive comprising antioxidant 0.1-0.2 wt% and metal complexing agent 0.01-0.02 wt%; and solvent in 86-96.5 wt%. The present invention provides one new veterinary medicine for treating animal's intestinal tract diseases and has the advantages of reasonable recipe, stable preparation, high bioavailability, determined curative effect, etc.
Owner:江西百思技术咨询有限公司
Fertilizer composition for preventing and curing kiwifruit canker and preparation method thereof
Owner:贵州三福生物科技有限公司 +1
Preparation method of ciprofloxacin lactate
The invention belongs to the technical field of medicine preparation and particularly relates to a preparation method of ciprofloxacin lactate. The method comprises the steps as follows: mixing ciprofloxacin hydrochloride with a solvent, adjusting pH with alkali, and performing cooling crystallization, filtration, drying and other steps to obtain ciprofloxacin; mixing ciprofloxacin with the solvent, adding a salt forming agent for a salt forming reaction, and then performing cooling crystallization, filtration, drying and other steps to obtain a finished product of ciprofloxacin lactate. The preparation method is simple to operate, the involved reaction condition is mild and easy to control, ciprofloxacin lactate is prepared in two steps, the refining process is omitted, the production cycle is shortened, the cost is greatly reduced, and the mass yield of ciprofloxacin lactate reaches 95% or higher, and the product purity can reach 99.5%.
Owner:HENAN KANGDA PHARMA
Preparation method for ciprofloxacin sodium chloride injection
InactiveCN108938636AAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateQuality control
The invention relates to the technical field of medical injection preparation and specially relates to a preparation method for a ciprofloxacin sodium chloride injection. The preparation method comprises the following preparation processes: preparing water for injection, weighting solute, preparing a concentrated solution, preparing a rare solution and encapsulating, sterilizing, inspecting with alamp, packaging, and the like. The dissolving uniformity of solutes in the water for injection is effectively increased under the mixing effect of special concentrated solution and rare solution andthrough the special preparation of the water for injection and the appropriate formula of ciprofloxacin injection; the purity of the processed ciprofloxacin injection is 99.0+ / -0.2%, through high-temperature and high-pressure sterilization, strict quality control and qualified packaging; the guarantee period is 24 months; no floccules or any visible suspended solids appear in the guarantee period;the medicinal value and the quality are both kept unchanged.
Owner:GUIZHOU TIANDI PHARMA
Compound injection for treating porcine diarrhea and preparation method thereof
InactiveCN101966330AReduce dosageImprove the immunityOrganic active ingredientsDigestive systemCiprofloxacin lactateSecondary Infections
The invention discloses a compound injection for treating porcine diarrhea and a preparation method thereof. Every 100ml of compound injection for treating the porcine diarrhea comprises the following components by weight: 5 to 15g of ciprofloxacin lactate, 3 to 10g of berberine, 2 to 5g of ginger, 1 to 5g of levamisole, 0.5 to 2g of mucosal repairing agent, 2 to 6g of organic cosolvent, 0.05 to 0.3g of antioxidant and the balance of injection water. The compound injection for treating the porcine diarrhea of the invention is prepared by combining the traditional Chinese medicine and foreign medicine, wherein the foreign medicine is formed by matching broad spectrum antibiotic and the levamisole serving as an immunoenhancement for quickly sterilizing, improving the resistance of the ill animals to bacteria and virus infection and preventing secondary infection of other virus diseases; and the traditional Chinese medicine is formed by matching berberine extracted from coptis and ginger juice for reducing the amount of used antibacterial, preventing the medicament resistance, reducing the residue of the medicament, effectively protecting gastrointestinal mucosa and simultaneously reducing the untoward reaction.
Owner:ZHENGZHOU HOUYI PHARMA
Preparation method of antibacterial spray containing electrostatic spinning fibers
InactiveCN113559062AGood biocompatibilityGood loading effectAntibacterial agentsOrganic active ingredientsFiberCiprofloxacin lactate
The invention discloses a preparation method of an antibacterial spray containing electrostatic spinning fibers. The preparation method comprises the following steps of preparing an electrostatic spinning solution containing ciprofloxacin lactate or norfloxacin; preparing an electrostatic spinning fiber containing the ciprofloxacin lactate or the norfloxacin; preparing electrostatic spinning short fibers containing the ciprofloxacin lactate or the norfloxacin; mixing the electrostatic spinning short fibers containing the ciprofloxacin lactate or the norfloxacin with 75% alcohol to obtain the spray with a long-acting antibacterial effect. According to the technical scheme, the durability of the antibacterial spray is improved, harm to a human body is avoided, and the defects of sprays or antibacterial nanoparticles with single components in a market are overcome.
Owner:THE FIFTH AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV
Ciprofloxacin thermo-sensitive type in-situ gel composition and preparing method thereof
ActiveCN103156805BNo medication dead endsImprove distributionAntibacterial agentsOrganic active ingredientsSodium acetateCiprofloxacin lactate
The invention discloses ciprofloxacin thermo-sensitive type in-situ gel composition and belongs to the field of veterinary drug preparations. The thermo-sensitive type in-situ gel composition comprises, by weight volume (g / ml), 5%-10% of ciprofloxacin, 20%-26% of poloxamer 407, 0.5%-10% of poloxamer 188, 0.01%-0.04% of edetic acid, 0.009%-0.03% of bacteriostatic agent, and 0.1%-0.2% of antioxidant. Solvent of the composition is acetic acid - sodium acetate buffer solution. The invention further discloses a preparing method of the composition. The ciprofloxacin thermo-sensitive type in-situ gel composition is liquid at room temperature, jelling temperature is close to body temperature, and therefore dosing is convenient and jelling speed is high, jelling strength and adhering function are good, the dosing can be achieved with accurate positioning, and loss of drug is reduced. Furthermore, the ciprofloxacin thermo-sensitive type in-situ gel composition and the preparing method thereof have controlled-releasing and long-acting functions, dosage is low, the number of times of dosing is small, harm caused by implants normally used is avoided, and pain of patients is relieved.
Owner:NANJING AGRICULTURAL UNIVERSITY +1
Method for preparing ciprofloxacin lactate sodium chloride injection
ActiveCN102716072BFix stability issuesSolve solubilityAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateHydrogen
The invention provides a method for preparing ciprofloxacin lactate sodium chloride injection, and belongs to the field of medicinal preparation. The method includes the steps: firstly, dissolving lactic acid and sodium hydroxide into water for injection to prepare lactic acid solution; secondly, sufficiently mixing ciprofloxacin serving as a raw material, edetate disodium, diluted hydrochloric acid and the water for injection to prepare ciprofloxacin solution; and finally, sufficiently mixing the prepared lactic acid solution and the prepared ciprofloxacin solution, adding sodium chloride for injection into the solution, mixing the sodium chloride with the solution, and adjusting the pH (potential of hydrogen) value, adjusting the volume, pre-filtering, degerming, filling and sealing and performing autoclaved sterilization, inspection and the like to prepare the ciprofloxacin lactate sodium chloride injection. The method has the advantages of simple and convenient process, no environmental pollution, low cost and the like, and the ciprofloxacin lactate sodium chloride injection prepared by the method is high in stability and quality.
Owner:GUANGZHOU NANXIN PHARMA
Dosing tank for production of ciprofloxacin lactate eye drops
PendingCN108636321AImprove stabilityAvoid vibrationChemical/physical/physico-chemical stationary reactorsCiprofloxacin lactateReaction rate
The invention discloses a dosing tank for production of ciprofloxacin lactate eye drops. The dosing tank comprises a tank body, a grinding hammer and a fixing ring, wherein a feeding pipe is mounted on the left side of the tank body; a drive motor is located on the right side of an aeration pump; a connecting shaft is mounted below the drive motor and connected with the upper end of a rotating shaft through a driving belt located on the outer side; a water inlet pipe is mounted on the left side of the tank body; the grinding hammer is located below a sleeve; a cutting net is mounted in the fixing ring and located on the outer side of the sleeve and above exhaust vents; scattering blades are arranged on the outer side of the fixing ring; a feed delivery pipe is mounted below the tank body.According to the dosing tank for production of the ciprofloxacin lactate eye drops, the raw material in the dosing tank is stirred by stirring blades, gas enters the liquid through the exhaust vents,so that liquid rolling rate is increased, material reaction is accelerated, and by means of the cutting net, bubble breakage is facilitated, and the reaction rate of gas and the material is increased.
Owner:JIANGSU XIANGRUI PHARMA CO LTD
Medicament for curing mixed infection of poultry and livestock and preparation method thereof
InactiveCN103127240AAvoid poor antagonismGood treatment effectOrganic active ingredientsAntiinfectivesCiprofloxacin lactateTherapeutic effect
The invention relates to a medicament for curing mixed infection of poultry and livestock. The medicament is composed of the following components: 3-7 parts of parisarc lactic acid ciprofloxacin, 8-12 parts of artemisin extracts, 3-8 parts of celandine extracts and 75-85 parts of excipients. According to the medicament, the parisarc lactic acid ciprofloxacin for curing the mixed infection is mixed with Chinese herb extracts, the parisarc lactic acid ciprofloxacin and the Chinese herb extracts are mixed fully and evenly, and then the several kinds of components are directly matched with each other to improve therapeutic effects. Meanwhile, the medicament avoids poor antagonistic actions between medicaments caused by simultaneous usage of the medicament and the other medicaments, and is low in cost and good in effects.
Owner:DINGZHENG ANIMAL PHARMA TIANJIN
Compound composition for treating bacterial diarrhoea of livestock and poultry
ActiveCN102488767BLow priceDelay drug resistanceAntibacterial agentsDigestive systemCiprofloxacin lactateDiarrhoea symptoms
The invention discloses a sticktight-containing compound composition for treating bacterial diarrhoea of livestock and poultry. The compound composition is characterized by comprising raw materials of, by weight, 3-15 parts of lactic acid ciprofloxacin, 0.02-0.2 part of atropine sulfate, 20-70 parts of sticktight, 20-40 parts of rhizoma atractylodis, 8-20 parts of dark plum and 5-10 parts of myrobalan. The compound composition is prepared by mixing well the raw materials according to the proportion. An addition into an animal fodder is 0.1%-0.8%. The composition of the invention can kill bacteria rapidly and alleviate diarrhoea symptom caused by bacteria rapidly, has good protective effect on intestinal tract and overcomes disadvantages of a simple western medicine, such as long curative effect, weak curative effect, slow symptom alleviation and disadvantage of slow effect performance of a simple traditional Chinese medicine; besides, usage of the composition has low medicine cost and creates high benefit for farmers. The composition can be prepared into a powder, an oral liquid, a particulate agent and a tablet.
Owner:广西南宁市桃源兽药厂
Veterinary ciprofloxacin lactate injection and preparation method thereof
InactiveCN107308106AEasy to useReduce stress responseAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateHydrogen
The invention discloses a veterinary ciprofloxacin lactate injection and belongs to the technical field of veterinary medicines. The injection comprises 25.5-127.5g ciprofloxacin lactate, 50-150g PVP (polyvinylpyrrolidone)-K30, 50-100g polyoxyethylene-40-hydrogenated castor oil, 5-15g sodium chloride, 0.5-5g sodium hydrogen sulfite and 2-10g lactic acid per 1000mL water for injection. A diffusion rate of the injection medicine is reduced significantly, so that the action time of ciprofloxacin lactate is prolonged.
Owner:山东中牧兽药有限公司
Novel technique of preparing lactic acid ciprofloxacin injection
ActiveCN100531735CStable release rateReduce labor intensity of injectionAntibacterial agentsOrganic active ingredientsHydrophilic polymersCiprofloxacin lactate
A new type ciprofloxacin lactate injection preparation method is provided, which is characterized in that: dissolve water-soluble ciprofloxacin lactate raw material in water, add hydrophilic polymers such as polyethylene glycol, propanediol and polyvinylpyrrolidone, etc. to form colloidal solution; wrap the drug in the hydrophilic colloidal solution to prolong the absorption duration of liquid medicine after the injection; add 2L water for injection to ciprofloxacin lactate, mix them evenly, add 3.5L polyethylene glycol, mix till full dissolution, then add sodium bisulfite and EDTA-2Na to mix till full dissolution, add water for injection to 10L, check whether the pH value is within the required scope of 3.0 to 5.0, conduct fine filtering with a filter that has the aperture of 0.45um and is qualified in integrity testing, then fill and pack the finished products as per the required specification.
Owner:PU LIKE BIO ENG +2
Veterinary-use lactic acid ciprofloxacin suppository and preparation method thereof
InactiveCN102836120BFully absorbedImprove bioavailabilityAntibacterial agentsOrganic active ingredientsDiseaseCiprofloxacin lactate
The invention discloses a veterinary-use lactic acid ciprofloxacin suppository and the preparation thereof. The suppository comprises, by weight, 1%-15% of lactic acid ciprofloxacin, 70%-98.5% of matrixes, and 0.5%-20% of sorbefacient. The veterinary-use lactic acid ciprofloxacin suppository improves the bioavailability of the lactic acid ciprofloxacin, enhances antibacterial effect of the lactic acid ciprofloxacin, and can be used to cure domestic-animal diseases such as endometritis and intestinal infection.
Owner:ZHENGZHOU HOUYI PHARMA
Preparation method of ciprofloxacin lactate sodium chloride injection
PendingCN114767627ANo need to adjust pHImprove stabilityAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateDisodium Edetate
The invention provides a preparation method of ciprofloxacin lactate sodium chloride injection, and belongs to the field of pharmaceutical preparations. The preparation method comprises the following steps: cleaning a liquid preparation system and a liquid medicine delivery pipeline by using an edetate disodium solution, then depolymerizing lactic acid under the acidic condition of hydrochloric acid, then fully stirring and uniformly mixing ciprofloxacin as a raw material with the acid-treated lactic acid, sodium chloride and water for injection, adjusting the volume of the prepared liquid, and performing freeze-drying to obtain the ciprofloxacin injection. Finally, the ciprofloxacin lactate sodium chloride injection can be prepared through the steps of ultrafiltration pyrogen removal, sterilization and filtration, potting, sealing performance detection, high-pressure sterilization, inspection and the like. The method has the advantages that the formula is simple, the prepared product does not contain edetate disodium, and the risk of complexing blood calcium is avoided; the pH value of the liquid medicine does not need to be adjusted; the process is simple; and pyrogen is removed by ultrafiltration, so that the medication safety of patients is ensured. The ciprofloxacin lactate sodium chloride injection prepared by the method is good in stability and excellent in product quality.
Owner:GUANGZHOU NUCIEN PHARM CO LTD +1
A kind of ciprofloxacin lactate injection for veterinary use and preparation method thereof
ActiveCN105147598BImprove stabilityNo precipitationAntibacterial agentsOrganic active ingredientsCiprofloxacin lactateSodium bisulfate
The invention belongs to the technical field of veterinary preparations and discloses a veterinary ciprofloxacin injection and preparation method thereof. The injection (per 1000ml) is composed of 25.5-127.5g of ciprofloxacin, 50-150g of PVP-K, 50-100g of nicotinamide, 5-15g of sodium chloride, 0.5-5g of sodium bisulfate, 2-10g of lactic acid and the rest of water for injection. The veterinary ciprofloxacin injection has the advantages that stability of the veterinary ciprofloxacin injection under the low-temperature condition (0-5 DEG C) can be improved, and action time of the ciprofloxacin can be prolonged.
Owner:浙江大飞龙动物保健品股份有限公司
Medicinal preparation for preventing and treating postpartum diseases of sows and preparation method thereof
InactiveCN105943685AReduce morbidityPromote healthy growthOrganic active ingredientsInorganic active ingredientsDiseasePuerperal disorder
The invention discloses a medicinal preparation for preventing and treating postpartum diseases of sows and a preparation method thereof. The medicinal preparation is prepared from the following components in parts by weight: 5-10 parts of lincomycin hydrochloride, 2-6 parts of ciprofloxacin lactate, 1-5 parts of sodium trimethoxypyrimidine lactate, 8-12 parts of lonicera japonica, 5-10 parts of houttuynia cordata, 1-5 parts of liquidambar formosana, 20-30 parts of medical stone, 2-5 parts of fructo-oligose and 0.5-2 parts of citric acid. The components are compatible and synergized to stimulate great appetite of sows, so that postpartum feed intake reduction and occurrence of postpartum diseases and mastitis can be effectively prevented, sow diestrus can be reduced, and sow utilization can be improved. Furthermore, the incidence rate of yellow and white scour of piglets can be reduced, healthy growth of piglets can be promoted, the ecological balance of intestinal flora can be regulated, and the side effect that intestinal intestine bacteria are disturbed by antibiotics can be greatly reduced. The medicinal preparation has a wide application prospect.
Owner:FUJIAN AONONG BIOLOGICAL TECH GRP CO LTD +1
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