45 results about "Ciprofloxacin lactate" patented technology

The invention discloses a fertilizer and pesticide combination reagent for preventing and killing bacterial canker of kiwifruit and a preparation method of the fertilizer and pesticide combination reagent. The fertilizer and pesticide combination reagent is prepared from the following raw materials in parts by weight: 200 parts of agricultural amino acid water soluble powder, 40-50 parts of anhydrous zinc chloride, 45-65 parts of anhydrous manganese chloride, 40-80 parts of a ciprofloxacin active compound or a ciprofloxacin active compound, 100-200 parts of a 14% methyl chloride isothiazolinone water agent, 100-150 parts of oxine-copper active compound, 0.1 part of forchlorfenuron, 0.1 part of a 5-nitroguaiacol sodium salt active compound, 0.5 part of an alpha-pimacol active compound, 350-450 parts of molasses microbial fermentation concentrate solution, 0.2-0.25 part of sodium polyacrylate powder, 50-60 parts of No.YD-7 liquid fertilizer synergia solution, 0.1-0.2 part of industrial alcohol and the balance of deionized water to supplement the raw materials to 1200-1250 parts. The fertilizer and pesticide combination reagent disclosed by the invention is a high-density liquid product with fertilizer and pesticide effects, has good affinity for both water and plants, mainly contact and kill plant bacteria, and can also kill pathogenic fungus. A layer of compact organic pesticide and fertilizer film is formed outside a tree body when the fertilizer and pesticide combination reagent is applied in large concentration, and a sustained release function is exerted.

The invention discloses ciprofloxacin thermo-sensitive type in-situ gel composition and belongs to the field of veterinary drug preparations. The thermo-sensitive type in-situ gel composition comprises, by weight volume (g / ml), 5%-10% of ciprofloxacin, 20%-26% of poloxamer 407, 0.5%-10% of poloxamer 188, 0.01%-0.04% of edetic acid, 0.009%-0.03% of bacteriostatic agent, and 0.1%-0.2% of antioxidant. Solvent of the composition is acetic acid - sodium acetate buffer solution. The invention further discloses a preparing method of the composition. The ciprofloxacin thermo-sensitive type in-situ gel composition is liquid at room temperature, jelling temperature is close to body temperature, and therefore dosing is convenient and jelling speed is high, jelling strength and adhering function are good, the dosing can be achieved with accurate positioning, and loss of drug is reduced. Furthermore, the ciprofloxacin thermo-sensitive type in-situ gel composition and the preparing method thereof have controlled-releasing and long-acting functions, dosage is low, the number of times of dosing is small, harm caused by implants normally used is avoided, and pain of patients is relieved.

The invention provides a method for preparing ciprofloxacin lactate sodium chloride injection, and belongs to the field of medicinal preparation. The method includes the steps: firstly, dissolving lactic acid and sodium hydroxide into water for injection to prepare lactic acid solution; secondly, sufficiently mixing ciprofloxacin serving as a raw material, edetate disodium, diluted hydrochloric acid and the water for injection to prepare ciprofloxacin solution; and finally, sufficiently mixing the prepared lactic acid solution and the prepared ciprofloxacin solution, adding sodium chloride for injection into the solution, mixing the sodium chloride with the solution, and adjusting the pH (potential of hydrogen) value, adjusting the volume, pre-filtering, degerming, filling and sealing and performing autoclaved sterilization, inspection and the like to prepare the ciprofloxacin lactate sodium chloride injection. The method has the advantages of simple and convenient process, no environmental pollution, low cost and the like, and the ciprofloxacin lactate sodium chloride injection prepared by the method is high in stability and quality.

A new type ciprofloxacin lactate injection preparation method is provided, which is characterized in that: dissolve water-soluble ciprofloxacin lactate raw material in water, add hydrophilic polymers such as polyethylene glycol, propanediol and polyvinylpyrrolidone, etc. to form colloidal solution; wrap the drug in the hydrophilic colloidal solution to prolong the absorption duration of liquid medicine after the injection; add 2L water for injection to ciprofloxacin lactate, mix them evenly, add 3.5L polyethylene glycol, mix till full dissolution, then add sodium bisulfite and EDTA-2Na to mix till full dissolution, add water for injection to 10L, check whether the pH value is within the required scope of 3.0 to 5.0, conduct fine filtering with a filter that has the aperture of 0.45um and is qualified in integrity testing, then fill and pack the finished products as per the required specification.

The invention belongs to the technical field of veterinary preparations and discloses a veterinary ciprofloxacin injection and preparation method thereof. The injection (per 1000ml) is composed of 25.5-127.5g of ciprofloxacin, 50-150g of PVP-K, 50-100g of nicotinamide, 5-15g of sodium chloride, 0.5-5g of sodium bisulfate, 2-10g of lactic acid and the rest of water for injection. The veterinary ciprofloxacin injection has the advantages that stability of the veterinary ciprofloxacin injection under the low-temperature condition (0-5 DEG C) can be improved, and action time of the ciprofloxacin can be prolonged.