Novel technique of preparing lactic acid ciprofloxacin injection

Abstract

A new type ciprofloxacin lactate injection preparation method is provided, which is characterized in that: dissolve water-soluble ciprofloxacin lactate raw material in water, add hydrophilic polymers such as polyethylene glycol, propanediol and polyvinylpyrrolidone, etc. to form colloidal solution; wrap the drug in the hydrophilic colloidal solution to prolong the absorption duration of liquid medicine after the injection; add 2L water for injection to ciprofloxacin lactate, mix them evenly, add 3.5L polyethylene glycol, mix till full dissolution, then add sodium bisulfite and EDTA-2Na to mix till full dissolution, add water for injection to 10L, check whether the pH value is within the required scope of 3.0 to 5.0, conduct fine filtering with a filter that has the aperture of 0.45um and is qualified in integrity testing, then fill and pack the finished products as per the required specification.

Description

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AI Technical Summary

Benefits of technology

The technology described by this inventor allows for better control over how much medication it dispenses with when injected into people's body compared to traditional methods like liquid or powder dosage forms that require manual administration. This results in improved patient compliance due to less effort required during treatment sessions.

Problems solved by technology

This patents describes how we have been working with certain substances called cloprofen (chemically known as 4-(pirimorpholin-4'-yl)-2H-1 -benzopyran), commonly referred to as an antiinflammatory agent, along with others like antibiotics and chemotherapy agents during veterinary medicine treatments. Clostridium perfrigerum has become one type of disease caused by bacterial growth, causing harmful symptoms including inflammation, fever, pain, swelling, dysfunctional gastrointestinal syndrome, necrosis, etc., especially when administered repeatedly throughout the lifetime of these subjects. To address this problem, researchers developed new techniques involving controllably releasing medicines from living organisms' bodies gradually without requiring multiple steps.